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N-Methyl-1-adamantylamine | CAS:3717-38-2
N-Methyl-1-adamantylamine
  • 名称:N-甲基-1-金刚烷胺 | N-Methyl-1-adamantylamine
  • CAS号:3717-38-2
  • 别名:N-Methyladamantanamine; N-Methyladamantine
  • 分子式:C11H19N
  • 分子量:165.28
  • EINESC号:

产品描述

物理化学性质

沸点 226.8±8.0 ºC (760 Torr
闪点 84.0±15.8 ºC, 计算值*
密度 1.00±0.1 g/cm3 (20 ºC

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New and forthcoming anti-epileptic drugs.Paolo Prunetti et al.Current opinion in neurology, 24(2), 159-164 (2011-02-09) Stiripentol, a putative antiepileptic drug, enhances the duration of opening of GABA-A receptor channels.Pascale P Quilichini et al.Epilepsia, 47(4), 704-716 (2006-05-03) Biphasic characteristic of interactions between stiripentol and carbamazepine in the mouse maximal electroshock-induced seizure model: a three-dimensional isobolographic analysis.Jarogniew J Luszczki et al.Naunyn-Schmiedeberg's archives of pharmacology, 374(1), 51-64 (2006-09-15) Acute hepatic injury in a child with Dravet syndrome: no protective effect of stiripentol.Joanne F Goorhuis et al.Seizure, 17(5), 477-478 (2008-04-11) Stiripentol in Dravet syndrome: results of a retrospective U.S. study.Elaine C Wirrell et al.Epilepsia, 54(9), 1595-1604 (2013-07-16) Efficacy of stiripentol in hyperthermia-induced seizures in a mouse model of Dravet syndrome.Dezhi Cao et al.Epilepsia, 53(7), 1140-1145 (2012-05-15) Ketogenic diet also benefits Dravet syndrome patients receiving stiripentol: a prospective pilot study.Rima Nabbout et al.Epilepsia, 52(7), e54-e57 (2011-05-17) New and forthcoming anti-epileptic drugs.Paolo Prunetti et al.Current opinion in neurology, 24(2), 159-164 (2011-02-09) Malignant migrating partial seizures of infancy controlled by stiripentol and clonazepam.Dana Merdariu et al.Brain & development, 35(2), 177-180 (2012-04-24) Stiripentol in childhood partial epilepsy: randomized placebo-controlled trial with enrichment and withdrawal design.Catherine Chiron et al.Journal of child neurology, 21(6), 496-502 (2006-09-05) Stiripentol. 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Drugs in R&D, 3(3), 220-222 (2002-07-09) Concentrations of stiripentol in children and adults with epilepsy: the influence of dose, age, and comedication.Theodor W May et al.Therapeutic drug monitoring, 34(4), 390-397 (2012-06-30) Ketogenic diet also benefits Dravet syndrome patients receiving stiripentol: a prospective pilot study.Rima Nabbout et al.Epilepsia, 52(7), e54-e57 (2011-05-17) Malignant migrating partial seizures of infancy controlled by stiripentol and clonazepam.Dana Merdariu et al.Brain & development, 35(2), 177-180 (2012-04-24) Topiramate in the treatment of highly refractory patients with Dravet syndrome.J Kröll-Seger et al.Neuropediatrics, 37(6), 325-329 (2007-03-16) Stiripentol: an example of antiepileptic drug development in childhood epilepsies.Rima Nabbout et al.European journal of paediatric neurology : EJPN : official journal of the European Paediatric Neurology Society, 16 Suppl 1, S13-S17 (2012-06-15) Exploring the potential of self-assembled mixed micelles in enhancing the stability and oral bioavailability of an acid-labile drug.Xingwang Zhang et al.European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences, 62, 301-308 (2014-06-24) [Clinical and genetic diagnosis of Dravet syndrome: report of 20 cases].Zsuzsa Siegler et al.Ideggyogyaszati szemle, 61(11-12), 402-408 (2008-12-17) Stiripentol. A novel antiepileptic drug.Michał K Trojnar et al.Pharmacological reports : PR, 57(2), 154-160 (2005-05-12) The effects of stiripentol on GABA(A) receptors.Janet L Fisher Epilepsia, 52 Suppl 2, 76-78 (2011-04-08) Vitamin C and Doxycycline: A synthetic lethal combination therapy targeting metabolic flexibility in cancer stem cells (CSCs).Ernestina Marianna De Francesco et al.Oncotarget, 8(40), 67269-67286 (2017-10-06) Characterization of the anticonvulsant, behavioral and pharmacokinetic interaction profiles of stiripentol in combination with clonazepam, ethosuximide, phenobarbital, and valproate using isobolographic analysis.Jarogniew J Luszczki et al.Epilepsia, 47(11), 1841-1854 (2006-11-23) The efficacy of bromides, stiripentol and levetiracetam in two patients with malignant migrating partial seizures in infancy.Milena Djuric et al.Epileptic disorders : international epilepsy journal with videotape, 13(1), 22-26 (2011-03-12) Identifying Drugs that Bind Selectively to Intersubunit General Anesthetic Sites in the α1β3γ2 GABAAR Transmembrane Domain.Selwyn S Jayakar et al.Molecular pharmacology, 95(6), 615-628 (2019-04-07) Screening of conventional anticonvulsants in a genetic mouse model of epilepsy.Hawkins NA, et al. 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Focus on flunarizine, fosphenytoin, midazolam and stiripentol.M Bebin et al.Drugs, 48(2), 153-171 (1994-08-01) Stiripentol.Catherine Chiron Expert opinion on investigational drugs, 14(7), 905-911 (2005-07-19) Stiripentol in severe myoclonic epilepsy in infancy: a randomised placebo-controlled syndrome-dedicated trial. STICLO study group.C Chiron et al.Lancet (London, England), 356(9242), 1638-1642 (2000-11-23) Stiripentol : in severe myoclonic epilepsy of infancy (dravet syndrome).Greg L Plosker CNS drugs, 26(11), 993-1001 (2012-09-29) Stiripentol.Catherine Chiron Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics, 4(1), 123-125 (2007-01-03) HIGHLY SENSITIVE SYNCHRONOUS SPECTROFLUORIMETRIC METHOD FOR DETERMINATION OF STIRIPENTOL IN CAPSULES AND HUMAN URINE: APPLICATION TO IN-VITRO DRUG RELEASE AND WEIGHT VARIATION TEST.Darwish HW, et al. 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