Roflumilast | CAS:162401-32-3
Roflumilast
- 名称:罗氟司特; 3-(环丙基甲氧基)-N-(3,5-二氯吡啶-4-基)-4-(二氟甲氧基)苯甲酰胺 | Roflumilast
- CAS号:162401-32-3
- 别名:3-(Cyclopropylmethoxy)-N-(3,5-dichloropyridin-4-yl)-4-(difluoromethoxy)benzamide
- 分子式:C17H14Cl2F2N2O3
- 分子量:403.21
- EINESC号:
产品描述
物理化学性质
没有数据 | 没有数据 |
---|
安全数据
没有数据 | 没有数据 |
---|
产品合成路线
更多
Related Intermediates
名称 | CAS号 | |
---|---|---|
4-Amino-3,5-dichloropyridine | 22889-78-7 | 查看 |
3-Cyclopropylmethoxy-4-difluoromethoxybenzoic acid | 162401-62-9 | 查看 |
3-(Cyclopropylmethoxy)-4-hydroxybenzoic acid methyl ester | 848574-60-7 | 查看 |
Methyl 3-(cyclopropylmethoxy)-4-(difluoromethoxy)benzoate | 680184-57-0 | 查看 |
3,4-Dihydroxybenzaldehyde | 139-85-5 | 查看 |
更多
文章
同行评议文献
Quantum dot-DNA aptamer conjugates coupled with capillary electrophoresis: A universal strategy for ratiometric detection of organophosphorus pesticides.Tingting Tang et al.Talanta, 146, 55-61 (2015-12-24)
Studies on heterocyclic compounds: 1,3-thiazolidin-4-ones from Schiff bases.E Piscopo et al.Bollettino della Societa italiana di biologia sperimentale, 64(2), 153-158 (1988-02-01)
Quantum dot-DNA aptamer conjugates coupled with capillary electrophoresis: A universal strategy for ratiometric detection of organophosphorus pesticides.Tingting Tang et al.Talanta, 146, 55-61 (2015-12-24)
Maternal Diabetes Leads to Adaptation in Embryonic Amino Acid Metabolism during Early Pregnancy.Jacqueline Gürke et al.PloS one, 10(5), e0127465-e0127465 (2015-05-29)
Determination of 2-mercaptopropionylglycine and its metabolite, 2-mercaptopropionic acid, in plasma by ion-pair reversed-phase high-performance liquid chromatography with post-column derivatization.P Leroy et al.Journal of chromatography, 564(1), 258-265 (1991-03-08)
Quantum dots-based fluorescent probes for turn-on and turn-off sensing of butyrylcholinesterase.Zhenzhen Chen et al.Biosensors & bioelectronics, 44, 204-209 (2013-02-23)
H/D exchange reactions in dinuclear iron thiolates as activity assay models of Fe-H2ase.X Zhao et al.Journal of the American Chemical Society, 123(39), 9710-9711 (2001-09-27)
The effect of phosphate on the nuclease activity of vanadium compounds.Nataliya Butenko et al.Journal of inorganic biochemistry, 147, 165-176 (2015-05-12)
The pharmacokinetics of tiopronin and its principal metabolite (2-mercaptopropionic acid) after oral administration to healthy volunteers.B Hercelin et al.European journal of clinical pharmacology, 43(1), 93-95 (1992-01-01)
Combined nitric oxide-releasing poly(vinyl alcohol) film/F127 hydrogel for accelerating wound healing.Fernanda Seabra Schanuel et al.Colloids and surfaces. B, Biointerfaces, 130, 182-191 (2015-04-25)
Studies on heterocyclic compounds: 1,3-thiazolidin-4-ones from Schiff bases.E Piscopo et al.Bollettino della Societa italiana di biologia sperimentale, 64(2), 153-158 (1988-02-01)
Identification, isolation, and characterization of cysteinate and thiolactate complexes of bismuth.Glen G Briand et al.Inorganic chemistry, 43(20), 6495-6500 (2004-09-28)
The pharmacokinetics of tiopronin and its principal metabolite (2-mercaptopropionic acid) after oral administration to healthy volunteers.B Hercelin et al.European journal of clinical pharmacology, 43(1), 93-95 (1992-01-01)
Kinetics of reactions of the Actinomadura R39 DD-peptidase with specific substrates.S A Adediran et al.Biochemistry, 50(3), 376-387 (2010-12-25)
Gold-mercaptopropionic acid-polyethylenimine composite based DNA sensor for early detection of rheumatic heart disease.Swati Singh et al.The Analyst, 139(14), 3600-3606 (2014-05-31)
DNA radiolysis by fast neutrons. II. Oxygen, thiols and ionic strength effects.M Spotheim-Maurizot et al.International journal of radiation biology, 59(6), 1313-1324 (1991-06-01)
Pharmacokinetics of tiopronin after repeated oral administration in rheumatoid arthritis.P Gillet et al.Fundamental & clinical pharmacology, 9(2), 205-206 (1995-01-01)
Mechanistic Scrutiny Identifies a Kinetic Role for Cytochrome b5 Regulation of Human Cytochrome P450c17 (CYP17A1, P450 17A1).Alexandr N Simonov et al.PloS one, 10(11), e0141252-e0141252 (2015-11-21)
Metabolism of fungicide diethofencarb in grape (Vitis vinifera L.): definitive identification of thiolactic acid conjugated metabolites.Takuo Fujisawa et al.Journal of agricultural and food chemistry, 51(18), 5329-5336 (2003-08-21)
Emission tunable, cyto/hemocompatible, near-IR-emitting Ag2S quantum dots by aqueous decomposition of DMSA.Ibrahim Hocaoglu et al.Nanoscale, 6(20), 11921-11931 (2014-09-02)
A carbohydrate biosensor surface for the detection of uropathogenic bacteria.K G Nilsson et al.Bio/technology (Nature Publishing Company), 12(13), 1376-1378 (1994-12-01)
Chemiluminescent determination of tiopronin and its metabolite, 2-mercaptopropionic acid, in urine by HPLC coupled with a flow injection set-up.Y Zhao et al.Biomedical chromatography : BMC, 11(2), 115-116 (1997-03-01)
Evidence for the formation of a mononuclear ferric-hydroperoxo complex via the reaction of dioxygen with an (N4S(thiolate))iron(II) complex.Yunbo Jiang et al.Chemical communications (Cambridge, England), (44)(44), 6828-6830 (2009-11-04)
Convenient test for screening metallo-beta-lactamase-producing gram-negative bacteria by using thiol compounds.Y Arakawa et al.Journal of clinical microbiology, 38(1), 40-43 (2000-01-05)
Interaction of digestive enzymes with tunable light emitting quantum dots: a thorough Spectroscopic investigation.Vaishnavi Ellappan et al.Luminescence : the journal of biological and chemical luminescence, 30(7), 978-989 (2015-02-11)
Rapid determination of glutamine in biological samples by high-performance liquid chromatography.T Teerlink et al.Clinica chimica acta; international journal of clinical chemistry, 218(2), 159-168 (1993-09-30)
Monitoring vigabatrin in head injury patients by cerebral microdialysis: obtaining pharmacokinetic measurements in a neurocritical care setting.Richard J Shannon et al.British journal of clinical pharmacology, 78(5), 981-995 (2014-05-08)
Ammonium thiolactate and thiolactic acid: important hairdressers' allergens?W Uter et al.Contact dermatitis, 46(4), 242-243 (2002-06-26)
Specificity studies of 3-Mercaptopyruvate sulfurtransferase.D W Porter et al.Journal of biochemical toxicology, 10(6), 287-292 (1995-12-01)
Ligand-controlled growth of ZnSe quantum dots in water during Ostwald ripening.Feng Jiang et al.Langmuir : the ACS journal of surfaces and colloids, 28(36), 12931-12940 (2012-08-14)
Near-infrared fluorescence probe for the determination of acid phosphatase and imaging of prostate cancer cells.Zihan Lin et al.The Analyst, 140(5), 1629-1636 (2015-01-30)
Prevalence of metallo-beta-lactamase among Pseudomonas aeruginosa and Acinetobacter baumannii in a Korean university hospital and comparison of screening methods for detecting metallo-beta-lactamase.Eun-Jee Oh et al.Journal of microbiological methods, 54(3), 411-418 (2003-07-05)
Highly luminescent and cytocompatible cationic Ag2S NIR-emitting quantum dots for optical imaging and gene transfection.Fatma Demir Duman et al.Nanoscale, 7(26), 11352-11362 (2015-06-13)
Synthesis and pharmacology of novel analogues of oxytocin and deaminooxytocin: directed methods for the construction of disulfide and trisulfide bridges in peptides.L Chen et al.Journal of medicinal chemistry, 40(6), 864-876 (1997-03-14)
Analyses of functional polymer-modified nanoparticles for protein sensing by surface-assisted laser desorption/ionization mass spectrometry coupled with HgTe nanomatrices.Hsiang-Yu Chang et al.Colloids and surfaces. B, Biointerfaces, 130, 157-163 (2015-04-22)
Quantitative analysis of thiols in consumer products on a microfluidic CE chip with fluorescence detection.Tobias Revermann et al.Electrophoresis, 28(7), 1154-1160 (2007-03-07)
Simple and sensitive progesterone detection in human serum using a CdSe/ZnS quantum dot-based direct binding assay.Sung-Duk Oh et al.Analytical biochemistry, 483, 54-61 (2015-05-13)
Development of tyrosinase biosensor based on quantum dots/chitosan nanocomposite for detection of phenolic compounds.En Han et al.Analytical biochemistry, 486, 102-106 (2015-07-15)
Occupational allergic contact dermatitis from thiolactic acid contained in 'ester-free' permanent-waving solutions.M Straube et al.Contact dermatitis, 34(3), 229-230 (1996-03-01)
Adhesion of quantum dots-induced membrane damage of Escherichia coli.Lu Lai et al.Journal of colloid and interface science, 389(1), 61-70 (2012-10-10)
Phosphorescent quantum dots/ethidium bromide nanohybrids based on photoinduced electron transfer for DNA detection.Lin Bi et al.Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy, 140, 479-483 (2015-02-02)
Quantification of total concentration of thiol functional groups in environmental samples by titration with monobromo(trimethylammonio)bimane and determination with tandem mass spectrometry.Khoa Huynh et al.Talanta, 218, 121109-121109 (2020-08-17)
备注
Products protected by valid patents are not offered for sale in countries where the sale of such products constitutes a patent infringement and its liability is at buyer's risk.
Products currently covered by valid US Patents are offered for R&D use in accordance with 35 USC 271 +A13(1).
Related Intermediates
名称 | CAS号 | |
---|---|---|
4-Amino-3,5-dichloropyridine | 22889-78-7 | 查看 |
3-Cyclopropylmethoxy-4-difluoromethoxybenzoic acid | 162401-62-9 | 查看 |
3-(Cyclopropylmethoxy)-4-hydroxybenzoic acid methyl ester | 848574-60-7 | 查看 |
Methyl 3-(cyclopropylmethoxy)-4-(difluoromethoxy)benzoate | 680184-57-0 | 查看 |
3,4-Dihydroxybenzaldehyde | 139-85-5 | 查看 |
相关产品
相关资讯
问
热门标签
询 单
请 填 写 相 关 信 息
- 请填写产品名称!
- CAS号
- 请正确填写公司名称!
- 请正确填写联系人!
- 请正确填写联系电话!
- 请正确填写联系邮箱!
- 请描述您的问题!