
Aurantimycin A | CAS:162478-50-4
Aurantimycin A
- 名称:Aurantimycin A | Aurantimycin A
- CAS号:162478-50-4
- 别名:
- 分子式:C38H64N8O14
- 分子量:856.96
- EINESC号:
产品描述
物理化学性质
密度 | 1.38±0.1 g/cm3 (20 ºC |
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Adoptive transfer of human gingiva-derived mesenchymal stem cells ameliorates collagen-induced arthritis via suppression of Th1 and Th17 cells and enhancement of regulatory T cell differentiation.Maogen Chen et al.Arthritis and rheumatism, 65(5), 1181-1193 (2013-02-13)
Extracellular ATP mediates the late phase of neutrophil recruitment to the lung in murine models of acute lung injury.Dilip Shah et al.American journal of physiology. Lung cellular and molecular physiology, 306(2), L152-L161 (2013-11-29)
Molecular characterization of six unrelated Italian patients affected by pyrimidine 5'-nucleotidase deficiency.Paola Bianchi et al.British journal of haematology, 122(5), 847-851 (2003-08-22)
Skeletal trauma generates systemic BMP2 activation that is temporally related to the mobilization of CD73+ cells.Richard Marsell et al.Journal of orthopaedic research : official publication of the Orthopaedic Research Society, 32(1), 17-23 (2013-09-11)
Mesenchymal stem cells and granulomas in Crohn's disease and intestinal tuberculosis: the way forward.Nayak Suprabha et al.Digestive diseases and sciences, 58(12), 3641-3641 (2013-10-29)
A quantitative atlas of mitotic phosphorylation.Noah Dephoure et al.Proceedings of the National Academy of Sciences of the United States of America, 105(31), 10762-10767 (2008-08-02)
Purification and properties of 5-nucleotidase.L A HEPPEL et al.The Journal of biological chemistry, 188(2), 665-676 (1951-02-01)
Etoposide and hypoxia do not activate apoptosis of multipotent mesenchymal stromal cells in vitro.J V Rylova et al.Bulletin of experimental biology and medicine, 154(1), 141-144 (2013-01-19)
5-Nucleotidase.J M Gulland et al.The Biochemical journal, 32(3), 597-601 (1938-03-01)
NMR structure in a membrane environment reveals putative amyloidogenic regions of the SEVI precursor peptide PAP(248-286).Ravi P R Nanga et al.Journal of the American Chemical Society, 131(49), 17972-17979 (2009-12-10)
Recruitment of beneficial M2 macrophages to injured spinal cord is orchestrated by remote brain choroid plexus.Ravid Shechter et al.Immunity, 38(3), 555-569 (2013-03-13)
Prostatic acid phosphatase expression in human tissues.Thomas J Graddis et al.International journal of clinical and experimental pathology, 4(3), 295-306 (2011-04-14)
Cloning and functional analysis of cDNAs with open reading frames for 300 previously undefined genes expressed in CD34+ hematopoietic stem/progenitor cells.Q H Zhang et al.Genome research, 10(10), 1546-1560 (2000-10-24)
Anti-human CD73 monoclonal antibody inhibits metastasis formation in human breast cancer by inducing clustering and internalization of CD73 expressed on the surface of cancer cells.Mikkel G Terp et al.Journal of immunology (Baltimore, Md. : 1950), 191(8), 4165-4173 (2013-09-18)
Dual, enzymatic and non-enzymatic, function of ecto-5'-nucleotidase (eN, CD73) in migration and invasion of A375 melanoma cells.Rafal Sadej et al.Acta biochimica Polonica, 59(4), 647-652 (2012-11-20)
Resistance revealed in acute lymphoblastic leukemia.Jon C Aster et al.Nature medicine, 19(3), 264-265 (2013-03-08)
The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).Daniela S Gerhard et al.Genome research, 14(10B), 2121-2127 (2004-10-19)
Nucleotide sequence of human prostatic acid phosphatase ACPP gene, including seven Alu repeats.F S Sharief et al.Biochemistry and molecular biology international, 33(3), 561-565 (1994-06-01)
Impaired Th1 immunity in ovarian cancer patients is mediated by TNFR2+ Tregs within the tumor microenvironment.Chindu Govindaraj et al.Clinical immunology (Orlando, Fla.), 149(1), 97-110 (2013-08-21)
Identification of Drosophila and human 7-methyl GMP-specific nucleotidases.Juliane Buschmann et al.The Journal of biological chemistry, 288(4), 2441-2451 (2012-12-12)
SLC28A3 genotype and gemcitabine rate of infusion affect dFdCTP metabolite disposition in patients with solid tumours.A Khatri et al.British journal of cancer, 110(2), 304-312 (2013-12-05)
Crystal structure of human cytosolic 5'-nucleotidase II: insights into allosteric regulation and substrate recognition.Karin Walldén et al.The Journal of biological chemistry, 282(24), 17828-17836 (2007-04-05)
Update in inclusion body myositis.Pedro Machado et al.Current opinion in rheumatology, 25(6), 763-771 (2013-09-27)
Purification, microsequencing, and immunolocalization of p36, a new interferon-alpha-induced protein that is associated with human lupus inclusions.S A Rich et al.The Journal of biological chemistry, 271(2), 1118-1126 (1996-01-12)
The main green tea polyphenol epigallocatechin-3-gallate counteracts semen-mediated enhancement of HIV infection.Ilona Hauber et al.Proceedings of the National Academy of Sciences of the United States of America, 106(22), 9033-9038 (2009-05-20)
CD73/5'-ecto-nucleotidase acts as a regulatory factor in osteo-/chondrogenic differentiation of mechanically stimulated mesenchymal stromal cells.A Ode et al.European cells & materials, 25, 37-47 (2013-01-10)
Human erythrocyte pyrimidine 5-nucleotidase, PN-I, is identical to p36, a protein associated to lupus inclusion formation in response to alpha-interferon.A Amici et al.Blood, 96(4), 1596-1598 (2000-08-15)
Human prostatic acid phosphatase, an authentic tyrosine phosphatase, dephosphorylates ErbB-2 and regulates prostate cancer cell growth.Tsai-Der Chuang et al.The Journal of biological chemistry, 285(31), 23598-23606 (2010-05-26)
Evaluation of molecular model-based discovery of ecto-5'-nucleotidase inhibitors on the basis of X-ray structures.Norbert Furtmann et al.Bioorganic & medicinal chemistry, 21(21), 6616-6622 (2013-09-10)
Nucleotide metabolic mismatches in mammalian hearts: implications for transplantation.Z Khalpey et al.Annals of the Royal College of Surgeons of England, 95(1), 9-14 (2013-01-16)
The DNA sequence and biological annotation of human chromosome 1.S G Gregory et al.Nature, 441(7091), 315-321 (2006-05-20)
Blockade of A2A receptors potently suppresses the metastasis of CD73+ tumors.Paul A Beavis et al.Proceedings of the National Academy of Sciences of the United States of America, 110(36), 14711-14716 (2013-08-22)
Prostatic acid phosphatase is not a prostate specific target.Ileana B Quintero et al.Cancer research, 67(14), 6549-6554 (2007-07-20)
Covalent modification and site-directed mutagenesis of an active site tryptophan of human prostatic acid phosphatase.Z Zhang et al.Acta biochimica Polonica, 44(4), 659-672 (1997-01-01)
Trypanosoma cruzi: effects of heat shock on ecto-ATPase activity.Naira Lígia Lima Giarola et al.Experimental parasitology, 133(4), 434-441 (2013-01-09)
Autoantibodies to cytosolic 5'-nucleotidase 1A in inclusion body myositis.Helma Pluk et al.Annals of neurology, 73(3), 397-407 (2013-03-06)
The high-resolution crystal structure of periplasmic Haemophilus influenzae NAD nucleotidase reveals a novel enzymatic function of human CD73 related to NAD metabolism.Silvia Garavaglia et al.The Biochemical journal, 441(1), 131-141 (2011-09-22)
Identification and characterization of inhibitors of cytoplasmic 5'-nucleotidase cN-II issued from virtual screening.Lars Petter Jordheim et al.Biochemical pharmacology, 85(4), 497-506 (2012-12-12)
Activating mutations in the NT5C2 nucleotidase gene drive chemotherapy resistance in relapsed ALL.Gannie Tzoneva et al.Nature medicine, 19(3), 368-371 (2013-02-05)
Integral and associated lysosomal membrane proteins.Bernd Schröder et al.Traffic (Copenhagen, Denmark), 8(12), 1676-1686 (2007-09-28)
Ecto-5'-nucleotidase (CD73) promotes tumor angiogenesis.Li Wang et al.Clinical & experimental metastasis, 30(5), 671-680 (2013-03-20)
Toward a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs.S Wiemann et al.Genome research, 11(3), 422-435 (2001-03-07)
Molecular basis of Japanese variants of pyrimidine 5'-nucleotidase deficiency.Hitoshi Kanno et al.British journal of haematology, 126(2), 265-271 (2004-07-09)
Relapse-specific mutations in NT5C2 in childhood acute lymphoblastic leukemia.Julia A Meyer et al.Nature genetics, 45(3), 290-294 (2013-02-05)
Rheumatoid factor B cell memory leads to rapid, switched antibody-forming cell responses.Rebecca A Sweet et al.Journal of immunology (Baltimore, Md. : 1950), 190(5), 1974-1981 (2013-02-01)
Anxiolytic effects of phosphodiesterase-2 inhibitors associated with increased cGMP signaling.Anbrin Masood et al.The Journal of pharmacology and experimental therapeutics, 331(2), 690-699 (2009-08-18)
The DNA sequence of human chromosome 7.Ladeana W Hillier et al.Nature, 424(6945), 157-164 (2003-07-11)
Crystal structure of the human ecto-5'-nucleotidase (CD73): insights into the regulation of purinergic signaling.Karen Knapp et al.Structure (London, England : 1993), 20(12), 2161-2173 (2012-11-13)
Diagnosis of pyrimidine 5'-nucleotidase deficiency suspected from a blood film.Hassan A Al-Jafar et al.American journal of hematology, 88(12), 1089-1089 (2013-07-31)
Lysine acetylation targets protein complexes and co-regulates major cellular functions.Chunaram Choudhary et al.Science (New York, N.Y.), 325(5942), 834-840 (2009-07-18)
Semen-derived amyloid fibrils drastically enhance HIV infection.Jan Münch et al.Cell, 131(6), 1059-1071 (2007-12-18)
Mass-spectrometric identification and relative quantification of N-linked cell surface glycoproteins.Bernd Wollscheid et al.Nature biotechnology, 27(4), 378-386 (2009-04-08)
Biomarkers of inclusion body myositis.Steven A Greenberg Current opinion in rheumatology, 25(6), 753-762 (2013-09-27)
Combining phenotypic and proteomic approaches to identify membrane targets in a 'triple negative' breast cancer cell type.Steven Rust et al.Molecular cancer, 12, 11-11 (2013-02-15)
The TCR ligand-inducible expression of CD73 marks γδ lineage commitment and a metastable intermediate in effector specification.Francis Coffey et al.The Journal of experimental medicine, 211(2), 329-343 (2014-02-05)
Evidence for essential catalytic determinants for human erythrocyte pyrimidine 5'-nucleotidase.A Amici et al.Cellular and molecular life sciences : CMLS, 62(14), 1613-1620 (2005-06-22)
The DNA sequence and comparative analysis of human chromosome 10.P Deloukas et al.Nature, 429(6990), 375-381 (2004-05-28)
Identification of novel markers for mouse CD4(+) T follicular helper cells.Smita S Iyer et al.European journal of immunology, 43(12), 3219-3232 (2013-09-14)
The sequence of the human genome.J C Venter et al.Science (New York, N.Y.), 291(5507), 1304-1351 (2001-02-22)
Signal sequence and keyword trap in silico for selection of full-length human cDNAs encoding secretion or membrane proteins from oligo-capped cDNA libraries.Tetsuji Otsuki et al.DNA research : an international journal for rapid publication of reports on genes and genomes, 12(2), 117-126 (2005-11-24)
Characterization of soluble vs membrane-bound human placental 5'-nucleotidase.M R Klemens et al.Biochemical and biophysical research communications, 172(3), 1371-1377 (1990-11-15)
TLR9 deficiency promotes CD73 expression in T cells and diabetes protection in nonobese diabetic mice.Ningwen Tai et al.Journal of immunology (Baltimore, Md. : 1950), 191(6), 2926-2937 (2013-08-21)
Standardization and safety of alveolar bone-derived stem cell isolation.S Mason et al.Journal of dental research, 93(1), 55-61 (2013-10-31)
Both MC5r and A2Ar are required for protective regulatory immunity in the spleen of post-experimental autoimmune uveitis in mice.Darren J Lee et al.Journal of immunology (Baltimore, Md. : 1950), 191(8), 4103-4111 (2013-09-18)
Nucleotide sequence of human prostatic acid phosphatase determined from a full-length cDNA clone.P G Tailor et al.Nucleic acids research, 18(16), 4928-4928 (1990-08-25)
Covalent structure, disulfide bonding, and identification of reactive surface and active site residues of human prostatic acid phosphatase.R L Van Etten et al.The Journal of biological chemistry, 266(4), 2313-2319 (1991-02-05)
Assessment of Anopheles salivary antigens as individual exposure biomarkers to species-specific malaria vector bites.Zakia M I Ali et al.Malaria journal, 11, 439-439 (2013-01-02)
Editorial: CD73 deficiency and immune dysregulation in HIV infection: cause or effect?Linda F Thompson Journal of leukocyte biology, 94(4), 545-547 (2013-10-02)
Molecular cloning of human cytosolic purine 5'-nucleotidase.J Oka et al.Biochemical and biophysical research communications, 205(1), 917-922 (1994-11-30)
Targeting CD73 enhances the antitumor activity of anti-PD-1 and anti-CTLA-4 mAbs.Bertrand Allard et al.Clinical cancer research : an official journal of the American Association for Cancer Research, 19(20), 5626-5635 (2013-08-29)
Structural origins of L(+)-tartrate inhibition of human prostatic acid phosphatase.M W LaCount et al.The Journal of biological chemistry, 273(46), 30406-30409 (1998-11-07)
Isolation and characterization of the promoter of the human 5'-nucleotidase (CD73)-encoding gene.K R Hansen et al.Gene, 167(1-2), 307-312 (1995-12-29)
Fibrils of prostatic acid phosphatase fragments boost infections with XMRV (xenotropic murine leukemia virus-related virus), a human retrovirus associated with prostate cancer.Seunghee Hong et al.Journal of virology, 83(14), 6995-7003 (2009-05-01)
Initial characterization of the human central proteome.Thomas R Burkard et al.BMC systems biology, 5, 17-17 (2011-01-29)
Loss of CD73-mediated actin polymerization promotes endometrial tumor progression.Jessica L Bowser et al.The Journal of clinical investigation, 126(1), 220-238 (2015-12-08)
5'-Nucleotidase of rat liver microsomes.H L SEGAL et al.The Journal of biological chemistry, 235, 471-474 (1960-02-01)
Glycoproteomics analysis of human liver tissue by combination of multiple enzyme digestion and hydrazide chemistry.Rui Chen et al.Journal of proteome research, 8(2), 651-661 (2009-01-23)
Elevated ecto-5'-nucleotidase-mediated increased renal adenosine signaling via A2B adenosine receptor contributes to chronic hypertension.Weiru Zhang et al.Circulation research, 112(11), 1466-1478 (2013-04-16)
Molecular cloning and sequence analysis of cDNA encoding human prostatic acid phosphatase.P Vihko et al.FEBS letters, 236(2), 275-281 (1988-08-29)
Complete sequencing and characterization of 21,243 full-length human cDNAs.Toshio Ota et al.Nature genetics, 36(1), 40-45 (2004-01-01)
Human cytosolic 5'-nucleotidase I: characterization and role in nucleoside analog resistance.S A Hunsucker et al.The Journal of biological chemistry, 276(13), 10498-10504 (2001-01-13)
Structure of human prostatic acid phosphatase gene.F S Sharief et al.Biochemical and biophysical research communications, 184(3), 1468-1476 (1992-05-15)
Cloning of a mouse cytosolic 5'-nucleotidase-I identifies a new gene related to human autoimmune infertility-related protein.G B Sala-Newby et al.Biochimica et biophysica acta, 1521(1-3), 12-18 (2001-11-03)
Expression of cell surface markers during self-renewal and differentiation of human adipose-derived stem cells.Tala Mohsen-Kanson et al.Biochemical and biophysical research communications, 430(3), 871-875 (2012-12-27)
Generation and annotation of the DNA sequences of human chromosomes 2 and 4.Ladeana W Hillier et al.Nature, 434(7034), 724-731 (2005-04-09)
Kindlin-2 regulates hemostasis by controlling endothelial cell-surface expression of ADP/AMP catabolic enzymes via a clathrin-dependent mechanism.Elzbieta Pluskota et al.Blood, 122(14), 2491-2499 (2013-07-31)
CD73 protein as a source of extracellular precursors for sustained NAD+ biosynthesis in FK866-treated tumor cells.Alessia Grozio et al.The Journal of biological chemistry, 288(36), 25938-25949 (2013-07-25)
Ecto-5'-nucleotidase, CD73, is an endothelium-derived hyperpolarizing factor synthase.Masanori Ohta et al.Arteriosclerosis, thrombosis, and vascular biology, 33(3), 629-636 (2013-01-05)
NT5E mutations and arterial calcifications.Cynthia St Hilaire et al.The New England journal of medicine, 364(5), 432-442 (2011-02-04)
Allosteric regulation and substrate activation in cytosolic nucleotidase II from Legionella pneumophila.Bharath Srinivasan et al.The FEBS journal, 281(6), 1613-1628 (2014-01-25)
Prostatic acid phosphatase degrades lysophosphatidic acid in seminal plasma.Masayuki Tanaka et al.FEBS letters, 571(1-3), 197-204 (2004-07-29)
DNA sequence of human chromosome 17 and analysis of rearrangement in the human lineage.Michael C Zody et al.Nature, 440(7087), 1045-1049 (2006-04-21)
Soluble ecto-5'-nucleotidase (5'-NT), alkaline phosphatase, and adenosine deaminase (ADA1) activities in neonatal blood favor elevated extracellular adenosine.Matthew Pettengill et al.The Journal of biological chemistry, 288(38), 27315-27326 (2013-07-31)
Genetic basis of hemolytic anemia caused by pyrimidine 5' nucleotidase deficiency.A M Marinaki et al.Blood, 97(11), 3327-3332 (2001-05-23)
The DNA sequence and analysis of human chromosome 6.A J Mungall et al.Nature, 425(6960), 805-811 (2003-10-24)
Crystallization and preliminary X-ray analysis of the open form of human ecto-5'-nucleotidase (CD73).Karen Maree Knapp et al.Acta crystallographica. Section F, Structural biology and crystallization communications, 68(Pt 12), 1545-1549 (2012-11-30)
Aminoquinoline surfen inhibits the action of SEVI (semen-derived enhancer of viral infection).Nadia R Roan et al.The Journal of biological chemistry, 285(3), 1861-1869 (2009-11-10)
Dengue virus type 2 modulates endothelial barrier function through CD73.Chinmay Patkar et al.The American journal of tropical medicine and hygiene, 88(1), 89-94 (2012-11-15)
Human prostatic acid phosphatase: cDNA cloning, gene mapping and protein sequence homology with lysosomal acid phosphatase.F S Sharief et al.Biochemical and biophysical research communications, 160(1), 79-86 (1989-04-14)
Contribution of the two domains of E. coli 5'-nucleotidase to substrate specificity and catalysis.Ulrike Krug et al.FEBS letters, 587(5), 460-466 (2013-01-22)
Crystal structure of human prostatic acid phosphatase .C G Jakob et al.The Prostate, 42(3), 211-218 (2000-01-19)
Crystal structures of human prostatic acid phosphatase in complex with a phosphate ion and alpha-benzylaminobenzylphosphonic acid update the mechanistic picture and offer new insights into inhibitor design.Eric Ortlund et al.Biochemistry, 42(2), 383-389 (2003-01-15)
Anti-CD73 therapy impairs tumor angiogenesis.Bertrand Allard et al.International journal of cancer, 134(6), 1466-1473 (2013-08-29)
CD73-dependent generation of adenosine and endothelial Adora2b signaling attenuate diabetic nephropathy.Eunyoung Tak et al.Journal of the American Society of Nephrology : JASN, 25(3), 547-563 (2013-11-23)
Host-derived CD4+ T cells attenuate stem cell-mediated transfer of autoimmune arthritis in lethally irradiated C57BL/6.g7 mice.Narendiran Rajasekaran et al.Arthritis and rheumatism, 65(3), 681-692 (2012-12-13)
Primary structure of human placental 5'-nucleotidase and identification of the glycolipid anchor in the mature form.Y Misumi et al.European journal of biochemistry, 191(3), 563-569 (1990-08-17)
Cytosolic 5'-nucleotidase 1A autoimmunity in sporadic inclusion body myositis.H Benjamin Larman et al.Annals of neurology, 73(3), 408-418 (2013-04-19)
Structures of the carbohydrate moieties of human prostatic acid phosphatase elucidated by H1 nuclear magnetic resonance spectroscopy.J M Risley et al.Archives of biochemistry and biophysics, 258(2), 404-412 (1987-11-01)
CD73 and adenosine generation in the creation of regulatory microenvironments.F S Regateiro et al.Clinical and experimental immunology, 171(1), 1-7 (2012-12-04)
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