询 单
请 填 写 相 关 信 息
产品信息
产品名称
别名
CAS号
结构式 上传
联系方式
公司
联系人
电话
邮箱
内容
提交
中文版 English
请输入产品名称、CAS式、分子式
Rilpivirine | CAS:500287-72-9
Rilpivirine
  • 名称:利匹韦林 | Rilpivirine
  • CAS号:500287-72-9
  • 别名:R 278474; TMC 278; 4-[[4-[[4-[(1E)-2-Cyanoethenyl]-2,6-dimethylphenyl]amino]-2-pyrimidinyl]amino]benzonitrile
  • 分子式:C22H18N6
  • 分子量:366.42
  • EINESC号:

产品描述

物理化学性质

熔点 245 ºC
密度 1.27

安全数据

没有数据没有数据

SDS

来源 SDS样本
Matrix 浏览或下载
Cayman 浏览或下载
产品合成路线
更多

Related Intermediates

名称 CAS号
(2Z)-3-(4-Amino-3,5-dimethylphenyl)-2-propenenitrile 661489-22-1 查看
4-Aminobenzonitrile 873-74-5 查看
4-[(4-Hydroxy-2-pyrimidinyl)amino]benzonitrile 189956-45-4 查看
4-[(4-Chloro-2-pyrimidinyl)amino]benzonitrile 244768-32-9 查看
4-Iodo-2,6-dimethylaniline 4102-53-8 查看
N-(4-Cyanophenyl)guanidine 5637-42-3 查看
(E)-3-(4-Amino-3,5-dimethylphenyl)-2-propenenitrile hydrochloride 661489-23-2 查看
4-Bromo-2,6-dimethylaniline 24596-19-8 查看
2-Amino-4-chloropyrimidine 3993-78-0 查看
更多
文章
同行评议文献
Population genetics of Haemophilus influenzae serotype a in three Canadian provinces.Raymond S W Tsang et al.Canadian journal of microbiology, 59(5), 362-364 (2013-05-08) Protective effect of secondary plant metabolites from Ipomoea aquatica Forsk. against carbofuran induced damages.Sanjukta Datta et al.Indian journal of experimental biology, 51(12), 1109-1119 (2014-03-04) [Influence of electroacupuncture intervention on free radical metabolism in athletes undergoing intensive endurance exercise].Jian-Yu Liu et al.Zhen ci yan jiu = Acupuncture research, 38(1), 48-51 (2013-05-09) Superoxide dismutase from escherichia coli B. A new manganese-containing enzyme.B B Keele et al.The Journal of biological chemistry, 245(22), 6176-6181 (1970-11-25) Electrochemistry and electrocatalytic activities of superoxide dismutases at gold electrodes modified with a self-assembled monolayer.Yang Tian et al.Analytical chemistry, 76(14), 4162-4168 (2004-07-16) Reply to Woodruff et al.: C1q and C3-dependent complement pathway activation does not contribute to disease in SOD1 mutant ALS mice.Christian S Lobsiger et al.Proceedings of the National Academy of Sciences of the United States of America, 111(1), E5-E5 (2014-02-21) [Protective effect of medicated serum prepared with taohong siwu tang on hydrogen peroxide-induced human umbilical vein endothelial cells].Zhu-Qing Liu et al.Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, 38(3), 402-406 (2013-05-15) Copper induced oxidative stress in tea (Camellia sinensis) leaves.D Saha et al.Journal of environmental biology, 33(5), 861-866 (2013-06-06) [Superoxide dismutase, malondialdehyde and proline as new quality criteria for Schizochytrium sp. fermentation].Li Zhang et al.Wei sheng wu xue bao = Acta microbiologica Sinica, 53(2), 136-144 (2013-05-01) Effects of depuration on oxidative biomarkers in tilapia (Oreochromis niloticus) after subchronic exposure to cyanobacterium producing cylindrospermopsin.R Guzmán-Guillén et al.Aquatic toxicology (Amsterdam, Netherlands), 149, 40-49 (2014-02-25) Anion binding properties of reduced and oxidized iron-containing superoxide dismutase reveal no requirement for tyrosine 34.Anne-Frances Miller et al.Biochemistry, 44(16), 5969-5981 (2005-04-20) Therapeutic effect of magnesium sulphate on carbon monoxide toxicity-mediated brain lipid peroxidation.Y Yavuz et al.European review for medical and pharmacological sciences, 17 Suppl 1, 28-33 (2013-04-26) [The antioxidant enzyme activity in mouse liver mitochondria after nanosecond pulsed periodic X-ray exposure].I R Kniazeva et al.Radiatsionnaia biologiia, radioecologiia, 53(2), 183-190 (2013-06-22) [Antioxidant properties of remaxol, reamberin, and ademetionine in patients with drug-induced liver injury on the background of antituberculous therapy].D S Sukhanov Eksperimental'naia i klinicheskaia farmakologiia, 76(4), 45-48 (2013-06-15) Myocardial toxicity of acute promyelocytic leukaemia drug-arsenic trioxide.V V Mathews et al.European review for medical and pharmacological sciences, 17 Suppl 1, 34-38 (2013-04-26) Superoxide dismutase from Streptococcus mutans. Isolation and characterization of two forms of the enzyme.P G Vance et al.The Journal of biological chemistry, 247(15), 4782-4786 (1972-08-10) Perinatal tobacco smoke exposure increases vascular oxidative stress and mitochondrial damage in non-human primates.David G Westbrook et al.Cardiovascular toxicology, 10(3), 216-226 (2010-07-30) [Protective effects of polysaccharides from Dendrobium huoshanense on CCl4-induced acute liver injury in mice].Jing Huang et al.Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, 38(4), 528-532 (2013-05-30) Characterization of differentially expressed stress-associated proteins in starch granule development under heat stress in wheat (Triticum aestivum L.).Ranjeet R Kumar et al.Indian journal of biochemistry & biophysics, 50(2), 126-138 (2013-06-01) [Advances of selenium supplementation in posttraumatic stress disorder risk group patients].V V Voĭtsekhovskis et al.Biomeditsinskaia khimiia, 60(1), 125-132 (2014-04-23) Decrease of reactive oxygen species-related biomarkers in the tissue-mimic 3D spheroid culture of human lung cells exposed to zinc oxide nanoparticles.Eunjoo Kim et al.Journal of nanoscience and nanotechnology, 14(5), 3356-3365 (2014-04-17) [Diabetes mellitus-related oxidative stress and its parameters in saliva].Dominika Bolesta et al.Polski merkuriusz lekarski : organ Polskiego Towarzystwa Lekarskiego, 35(209), 300-304 (2014-03-01) Association of dietary vitamin C and e intake and antioxidant enzymes in type 2 diabetes mellitus patients.Zahra Rafighi et al.Global journal of health science, 5(3), 183-187 (2013-04-27) Intercellular propagated misfolding of wild-type Cu/Zn superoxide dismutase occurs via exosome-dependent and -independent mechanisms.Leslie I Grad et al.Proceedings of the National Academy of Sciences of the United States of America, 111(9), 3620-3625 (2014-02-20) [Cytoplasmic superoxide dismutase activity is a sensitive indicator of the antioxidant status of the rat liver and brain].T V Sirota et al.Biomeditsinskaia khimiia, 60(1), 63-71 (2014-04-23) [Protective effect of different solvent extracts from platycladi cacumen carbonisatum on LPS-induced human umbilical vein endothelial cells damage].Li-Na Zhou et al.Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, 38(22), 3933-3938 (2014-02-25) [Hepatoprotective properties of isoflavonoids from roots of Maackia amurensis on experimental carbon tetrachloride-induced hepatic damage].N F Kushnerova et al.Eksperimental'naia i klinicheskaia farmakologiia, 77(2), 26-30 (2014-05-06) Taurine attenuates oxidative stress and alleviates cardiac failure in type I diabetic rats.Guo-guang Wang et al.Croatian medical journal, 54(2), 171-179 (2013-05-01) [Influence of transition metal compounds on superoxide dismutase activity of sulfur reducing Desulfuromonas acetoxidans bacteria].O M Vasyliv et al.Mikrobiolohichnyi zhurnal (Kiev, Ukraine : 1993), 75(2), 37-44 (2013-06-01) [Effect of cordyceps polysaccharide on lipid peroxidation of rats with dimethylnitrosamine-induced liver fibrosis].Jing-Hua Peng et al.Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, 38(3), 391-396 (2013-05-15) Extracellular superoxide dismutase, a potential extracellular biomarker candidate for prolactinoma.J Yang et al.The West Indian medical journal, 61(7), 665-669 (2013-04-30) Cloning, expression, and purification of a Cu/Zn superoxide dismutase from Jatropha curcas.Ou-Yang Chao et al.Zeitschrift fur Naturforschung. C, Journal of biosciences, 68(1-2), 60-69 (2013-05-11) Further characterization of bovine superoxide dismutase and its isolation from bovine heart.B B Keele et al.The Journal of biological chemistry, 246(9), 2875-2880 (1971-05-10) [Effect of acupuncture intervention on learning-memory ability and cerebral superoxide dismutase activity and malonaldehyde concentration in chronic fatigue syndrome rats].Chang-zheng Liu et al.Zhen ci yan jiu = Acupuncture research, 38(6), 478-481 (2014-03-04) [Development of Scotch pine seedlings and functioning of antioxidant systems under the chronic action of lead ions].Iu V Ivanov et al.Izvestiia Akademii nauk. Seriia biologicheskaia, (1)(1), 32-42 (2013-05-15) Sirtuin 1 attenuates oxidative stress via upregulation of superoxide dismutase 2 and catalase in astrocytes.Yi Cheng et al.Journal of neuroimmunology, 269(1-2), 38-43 (2014-02-26) Protective effect of alcoholic extract of Entada pursaetha DC. against CCl4-induced hepatotoxicity in rats.Gaurav Gupta et al.Indian journal of experimental biology, 52(3), 207-214 (2014-03-29) The antioxidant effects of pumpkin seed oil on subacute aflatoxin poisoning in mice.Gökhan Eraslan et al.Environmental toxicology, 28(12), 681-688 (2014-03-05) Preclinical research: Make mouse studies work.Steve Perrin Nature, 507(7493), 423-425 (2014-03-29) [Plasma levels of anti-oxidant markers during general anesthesia--a comparison between remifentanil- and epidural-based anesthesia].Kei Enohata et al.Masui. The Japanese journal of anesthesiology, 63(3), 328-332 (2014-04-15) The free radical scavenger, edaravone, ameliorates delayed neuropsychological sequelae after acute carbon monoxide poisoning in rabbits.Wang Qingsong et al.Undersea & hyperbaric medicine : journal of the Undersea and Hyperbaric Medical Society, Inc, 40(3), 223-229 (2013-06-26) The effects of resveratrol on oxidant/antioxidant systems and their cofactors in rats.Güzin Ozelçi Kavas et al.Advances in clinical and experimental medicine : official organ Wroclaw Medical University, 22(2), 151-155 (2013-05-28) Hypolipidemic and antioxidant activity of ethanolic extract of Symplocos racemosa Roxb. in hyperlipidemic rats: an evidence of participation of oxidative stress in hyperlipidemia.A M Durkar et al.Indian journal of experimental biology, 52(1), 36-45 (2014-03-13) Alteration of T-cell subpopulations and lipid peroxidation in the blood of patients with vulvar non-neoplastic epithelial disorder.G T Li et al.Clinical and experimental obstetrics & gynecology, 41(2), 174-176 (2014-05-02) [Construction of prokaryotic expression vector, expression and purification of ginseng Cu/Zn superoxide dismutase].Hong-Mei Lin et al.Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, 38(23), 4052-4055 (2014-05-06) Effects of hyperbaric oxygen on the expression of endogenous matrix metalloproteinase 9 in rat lung tissue.Pu You et al.Undersea & hyperbaric medicine : journal of the Undersea and Hyperbaric Medical Society, Inc, 41(1), 1-7 (2014-03-22) Direct detection of neuropeptide dynorphin A binding to the second extracellular loop of the κ opioid receptor using a soluble protein scaffold.Johannes Björnerås et al.The FEBS journal, 281(3), 814-824 (2014-03-13) Oxidative stress, antioxidant defenses and nitric oxide production following hyperoxic exposures.H G Gasier et al.Undersea & hyperbaric medicine : journal of the Undersea and Hyperbaric Medical Society, Inc, 40(2), 125-134 (2013-05-21) Small-molecule activator of glutamate transporter EAAT2 translation provides neuroprotection.Qiongman Kong et al.The Journal of clinical investigation, 124(3), 1255-1267 (2014-02-27) Microglia induce motor neuron death via the classical NF-κB pathway in amyotrophic lateral sclerosis.Ashley E Frakes et al.Neuron, 81(5), 1009-1023 (2014-03-13) Flexibility in monomeric Cu,Zn superoxide dismutase detected by limited proteolysis and molecular dynamics simulation.M Falconi et al.Proteins, 47(4), 513-520 (2002-05-10) Dynamics of rhizosphere properties and antioxidative responses in wheat (Triticum aestivum L.) under cadmium stress.Yonghua Li et al.Ecotoxicology and environmental safety, 102, 55-61 (2014-03-04) Protective effect of secondary plant metabolites from Ipomoea aquatica Forsk. against carbofuran induced damages.Sanjukta Datta et al.Indian journal of experimental biology, 51(12), 1109-1119 (2014-03-04) Effects of manganese superoxide dismutase (MnSOD) expression on regulation of esophageal cancer cell growth and apoptosis in vitro and in nude mice.Guogui Sun et al.Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine, 34(3), 1409-1419 (2013-05-08) Superoxide dismutase from escherichia coli B. A new manganese-containing enzyme.B B Keele et al.The Journal of biological chemistry, 245(22), 6176-6181 (1970-11-25) Perinatal tobacco smoke exposure increases vascular oxidative stress and mitochondrial damage in non-human primates.David G Westbrook et al.Cardiovascular toxicology, 10(3), 216-226 (2010-07-30) From mice to men: gene therapy's future for treatment of myocardial infarction.Brian G Kral et al.Circulation. Cardiovascular imaging, 6(3), 360-362 (2013-05-23) L-arginine attenuates oxidative stress condition during cardiomyopathy.Pratima Tripathi et al.Indian journal of biochemistry & biophysics, 50(2), 99-104 (2013-06-01) Preparation and physicochemical properties of green pea superoxide dismutase.Y Sawada et al.Biochimica et biophysica acta, 268(2), 305-312 (1972-05-12)
备注

Products protected by valid patents are not offered for sale in countries where the sale of such products constitutes a patent infringement and its liability is at buyer's risk.

Products currently covered by valid US Patents are offered for R&D use in accordance with 35 USC 271 +A13(1).

Related Intermediates
名称 CAS号
(2Z)-3-(4-Amino-3,5-dimethylphenyl)-2-propenenitrile 661489-22-1 查看
4-Aminobenzonitrile 873-74-5 查看
4-[(4-Hydroxy-2-pyrimidinyl)amino]benzonitrile 189956-45-4 查看
4-[(4-Chloro-2-pyrimidinyl)amino]benzonitrile 244768-32-9 查看
4-Iodo-2,6-dimethylaniline 4102-53-8 查看
N-(4-Cyanophenyl)guanidine 5637-42-3 查看
(E)-3-(4-Amino-3,5-dimethylphenyl)-2-propenenitrile hydrochloride 661489-23-2 查看
4-Bromo-2,6-dimethylaniline 24596-19-8 查看
2-Amino-4-chloropyrimidine 3993-78-0 查看

相关产品

相关资讯

热门标签
询 单
请 填 写 相 关 信 息
产品信息
产品名称
别名
CAS号
结构式 上传
联系方式
公司
联系人
电话
邮箱
内容
提交