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3-(4-Hydroxybutyl)-1H-indole-5-carbonitrile | CAS:914927-40-5
3-(4-Hydroxybutyl)-1H-indole-5-carbonitrile
  • 名称:3-(4-羟基丁基)-1H-吲哚-5-甲腈 | 3-(4-Hydroxybutyl)-1H-indole-5-carbonitrile
  • CAS号:914927-40-5
  • 别名:
  • 分子式:C13H14N2O
  • 分子量:214.26
  • EINESC号:

产品描述

物理化学性质

沸点 467 ºC
闪点 236 ºC
密度 1.21

安全数据

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SDS

来源 SDS样本
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Peptide amidating enzymes are present in cultured endothelial cells.C D Oldham et al.Biochemical and biophysical research communications, 184(1), 323-329 (1992-04-15) Peptidylglycine-alpha-hydroxylating monooxygenase generates two hydroxylated products from its mechanism-based suicide substrate, 4-phenyl-3-butenoic acid.W J Driscoll et al.Biochemistry, 39(27), 8007-8016 (2000-07-13) The phenylacetyl-CoA catabolon: a complex catabolic unit with broad biotechnological applications.J M Luengo et al.Molecular microbiology, 39(6), 1434-1442 (2001-03-22) Glycine-extended adrenomedullin exerts vasodilator effect through amidation in the rat aorta.Yuan-Ning Cao et al.Regulatory peptides, 113(1-3), 109-114 (2003-04-11) Oleic acid derived metabolites in mouse neuroblastoma N18TG2 cells.David J Merkler et al.Biochemistry, 43(39), 12667-12674 (2004-09-29) p38 MAPK activation, JNK inhibition, neoplastic growth inhibition, and increased gap junction communication in human lung carcinoma and Ras-transformed cells by 4-phenyl-3-butenoic acid.Diane F Matesic et al.Journal of cellular biochemistry, 113(1), 269-281 (2011-09-08) Probing the peptidylglycine alpha-hydroxylating monooxygenase active site with novel 4-phenyl-3-butenoic acid based inhibitors.Emma Langella et al.ChemMedChem, 5(9), 1568-1576 (2010-08-18) Fragrance material review on 4-phenyl-3-buten-2-ol.J Scognamiglio et al.Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 50 Suppl 2, S120-S123 (2011-10-29) Intracellular angiotensin II increases the long isoform of PDGF mRNA in rat hepatoma cells.Julia L Cook et al.Journal of molecular and cellular cardiology, 34(11), 1525-1537 (2002-11-15) Study of polarized IR spectra of the hydrogen bond system in crystals of styrylacetic acid.Henryk T Flakus et al.Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy, 65(2), 481-489 (2006-03-11) Anti-inflammatory effects of 4-phenyl-3-butenoic acid and 5-(acetylamino)-4-oxo-6-phenyl-2-hexenoic acid methyl ester, potential inhibitors of neuropeptide bioactivation.John D Bauer et al.The Journal of pharmacology and experimental therapeutics, 320(3), 1171-1177 (2006-12-02) Selective mechanism-based inactivation of peptidylglycine alpha-hydroxylating monooxygenase in serum and heart atrium vs. brain.F N Bolkenius et al.Biochemical pharmacology, 53(11), 1695-1702 (1997-06-01) Isolation and antifungal activity of 4-phenyl-3-butenoic acid from Streptomyces koyangensis strain VK-A60.Jee Yeon Lee et al.Journal of agricultural and food chemistry, 53(20), 7696-7700 (2005-09-30) In vivo inhibition of peptidylglycine-alpha-hydroxylating monooxygenase by 4-phenyl-3-butenoic acid.G P Mueller et al.The Journal of pharmacology and experimental therapeutics, 290(3), 1331-1336 (1999-08-24) Peptidyl-glycine alpha-amidating monooxygenase targeting and shaping of atrial secretory vesicles: inhibition by mutated N-terminal ProANP and PBA.Vénus Labrador et al.Circulation research, 95(12), e98-109 (2004-11-13) Reversal of the transformed phenotype and inhibition of peptidylglycine alpha-monooxygenase in Ras-transformed cells by 4-phenyl-3-butenoic acid.Jeffrey A Sunman et al.Molecular carcinogenesis, 41(4), 231-246 (2004-10-07) 4-Phenyl-3-butenoic acid, an in vivo inhibitor of peptidylglycine hydroxylase (peptide amidating enzyme).A F Bradbury et al.European journal of biochemistry, 189(2), 363-368 (1990-04-30) Autocrine growth loops dependent on peptidyl alpha-amidating enzyme as targets for novel tumor cell growth inhibitors.N Iwai et al.Lung cancer (Amsterdam, Netherlands), 23(3), 209-222 (1999-07-21) Vascular and endothelial actions of inhibitors of substance P amidation.G A Abou-Mohamed et al.Journal of cardiovascular pharmacology, 35(6), 871-880 (2000-06-03) Antiinflammatory and analgesic activity of an inhibitor of neuropeptide amidation.A A Ogonowski et al.The Journal of pharmacology and experimental therapeutics, 280(2), 846-853 (1997-02-01) Streptomyces koyangensis sp. nov., a novel actinomycete that produces 4-phenyl-3-butenoic acid.Jee Yeon Lee et al.International journal of systematic and evolutionary microbiology, 55(Pt 1), 257-262 (2005-01-18) Synthesis and antimalarial and antituberculosis activities of a series of natural and unnatural 4-methoxy-6-styryl-pyran-2-ones, dihydro analogues and photo-dimers.Stephen T McCracken et al.Bioorganic & medicinal chemistry, 20(4), 1482-1493 (2012-01-31) Enhanced neuropeptide Y synthesis during intermittent hypoxia in the rat adrenal medulla: role of reactive oxygen species-dependent alterations in precursor peptide processing.Gayatri Raghuraman et al.Antioxidants & redox signaling, 14(7), 1179-1190 (2010-09-15)
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