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1-Methyl-1H-indazole-4-carboxylic acid methyl ester | CAS:1071428-42-6
1-Methyl-1H-indazole-4-carboxylic acid methyl ester
  • 名称:1-甲基-1H-吲唑-4-羧酸甲酯 | 1-Methyl-1H-indazole-4-carboxylic acid methyl ester
  • CAS号:1071428-42-6
  • 别名:
  • 分子式:C10H10N2O2
  • 分子量:190.20
  • EINESC号:

产品描述

物理化学性质

密度 1.23±0.1 g/cm3 (20 ºC

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来源 SDS样本
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Degradation kinetics of metronidazole and olsalazine by bacteria in ascending colon and in feces of healthy adults.Maria Vertzoni et al.International journal of pharmaceutics, 413(1-2), 81-86 (2011-05-05) Role of mesalazine in acute and long-term treatment of ulcerative colitis and its complications.K W Schroeder Scandinavian journal of gastroenterology. Supplement, (236)(236), 42-47 (2002-11-01) Aminosalicylate therapy in the prevention of dysplasia and colorectal cancer in ulcerative colitis.David T Rubin et al.Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association, 4(11), 1346-1350 (2006-10-25) Treatment of ulcerative colitis with oral mesalamine: advances in drug formulation, efficacy expectations and dose response, compliance, and chemoprevention.William J Sandborn Reviews in gastroenterological disorders, 6(2), 97-105 (2006-05-16) Inhibition of human thiopurine S-methyltransferase by various nonsteroidal anti-inflammatory drugs in vitro: a mechanism for possible drug interactions.Kersti Oselin et al.Drug metabolism and disposition: the biological fate of chemicals, 35(9), 1452-1454 (2007-06-08) [Characterization of proteinuria in patients with ulcerative colitis and therapy with aminosalicylates].Lutz Buschhausen et al.Medizinische Klinik (Munich, Germany : 1983), 101(10), 791-795 (2006-10-14) Molecular nanofibers of olsalazine form supramolecular hydrogels for reductive release of an anti-inflammatory agent.Xinming Li et al.Journal of the American Chemical Society, 132(50), 17707-17709 (2010-12-03) Different therapy for different types of ulcerative colitis in China.Xue-Liang Jiang et al.World journal of gastroenterology, 10(10), 1513-1520 (2004-05-11) Study of the plasma pharmacokinetics and faecal excretion of the prodrug olsalazine and its metabolites after oral administration to horses.U Knoll et al.Journal of veterinary pharmacology and therapeutics, 25(2), 135-143 (2002-05-10) Thrombocytopenia associated with 5-aminosalicylate prodrug, olsalazine: is the devil still there?Yuefeng Rao et al.International journal of clinical pharmacy, 35(4), 529-531 (2013-04-30) Efficacy of drugs used in the treatment of IBD and combinations thereof in acute DSS-induced colitis in mice.Holger Sann et al.Life sciences, 92(12), 708-718 (2013-02-13) Treating TNBS-induced colitis in rats with probiotics.Yue-Meng Wan et al.The Turkish journal of gastroenterology : the official journal of Turkish Society of Gastroenterology, 22(5), 486-493 (2012-01-12) Comparison of the electrochemical properties of some colon-specific prodrugs of mesalazine.B Nigović et al.Die Pharmazie, 57(7), 468-470 (2002-08-10) Efficacy and tolerability of olsalazine (dipentum) in the treatment of patients with ulcerative colitis--results of a field study.M V Singer et al.Hepato-gastroenterology, 53(69), 317-321 (2006-06-27) When less is not more but at least equivalent.Stephen Holland Inflammatory bowel diseases, 10(6), 890-891 (2005-01-01) Comparative analysis of the in vitro prosecretory effects of balsalazide, sulfasalazine, olsalazine, and mesalamine in rabbit distal ileum.Keri A Kles et al.Inflammatory bowel diseases, 11(3), 253-257 (2005-03-01) Efficacy of a novel sphingosine kinase inhibitor in experimental Crohn's disease.Lynn W Maines et al.Inflammopharmacology, 18(2), 73-85 (2010-02-13) High thiopurine metabolite concentrations associated with lymphopenia in inflammatory bowel disease (IBD) pediatric patients receiving aminosalicylates combined with azathioprine.T-M-H Nguyen et al.International journal of clinical pharmacology and therapeutics, 48(4), 275-281 (2010-04-01) The short- and long-term safety of 5-aminosalicylate products in the treatment of ulcerative colitis.Danial E Baker et al.Reviews in gastroenterological disorders, 4(2), 86-91 (2004-06-10) [Oral therapy instead of enemas]. MMW Fortschritte der Medizin, 145(8), 56-56 (2003-03-29) The effect of 5-aminosalicylic acid-containing drugs on sulfide production by sulfate-reducing and amino acid-fermenting bacteria.Laurie M Edmond et al.Inflammatory bowel diseases, 9(1), 10-17 (2003-03-27) A prospective randomized observer-blind 2-year trial of azathioprine monotherapy versus azathioprine and olsalazine for the maintenance of remission of steroid-dependent ulcerative colitis.Gerassimos J Mantzaris et al.The American journal of gastroenterology, 99(6), 1122-1128 (2004-06-08) The specific type-4 phosphodiesterase inhibitor mesopram alleviates experimental colitis in mice.Florian Loher et al.The Journal of pharmacology and experimental therapeutics, 305(2), 549-556 (2003-02-28) New pH-sensitive glycopolymers for colon-specific drug delivery.M Mahkam Drug delivery, 14(3), 147-153 (2007-04-25) Systematic review: short-term adverse effects of 5-aminosalicylic acid agents in the treatment of ulcerative colitis.E V Loftus et al.Alimentary pharmacology & therapeutics, 19(2), 179-189 (2004-01-16)
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