
6-Chloro-2-(1,1-dimethylethyl)-N-methoxy-N-methyl-7-benzoxazolesulfonamide | CAS:1206896-20-9
6-Chloro-2-(1,1-dimethylethyl)-N-methoxy-N-methyl-7-benzoxazolesulfonamide
- 名称:6-氯-2-叔丁基-N-甲氧基-N-甲基-7-苯并恶唑磺酰胺 | 6-Chloro-2-(1,1-dimethylethyl)-N-methoxy-N-methyl-7-benzoxazolesulfonamide
- CAS号:1206896-20-9
- 别名:
- 分子式:C13H17ClN2O4S
- 分子量:332.80
- EINESC号:
产品描述
物理化学性质
密度 | 1.330±0.06 g/cm3 (20 º |
---|
安全数据
没有数据 | 没有数据 |
---|
SDS
来源 | SDS样本 |
---|---|
没有数据 | 没有数据 |
产品合成路线
名称 | CAS号 |
---|
更多
文章
同行评议文献
Selected drugs that inhibit DNA methylation can preferentially kill p53 deficient cells.Lan Yi et al.Oncotarget, 5(19), 8924-8936 (2014-09-23)
IMP-GMP specific cytosolic 5'-nucleotidase regulates nucleotide pool and prodrug metabolism.Federico Cividini et al.Biochimica et biophysica acta, 1850(7), 1354-1361 (2015-04-11)
Epigenetic Regulation of the Sex Determination Gene MeGI in Polyploid Persimmon.Takashi Akagi et al.The Plant cell, 28(12), 2905-2915 (2016-12-14)
Maternal Deprivation Enhances Contextual Fear Memory via Epigenetically Programming Second-Hit Stress-Induced Reelin Expression in Adult Rats.Run-Hua Wang et al.The international journal of neuropsychopharmacology, 21(11), 1037-1048 (2018-09-01)
Repair of DNA Damage Induced by the Cytidine Analog Zebularine Requires ATR and ATM in Arabidopsis.Chun-Hsin Liu et al.The Plant cell, 27(6), 1788-1800 (2015-05-30)
DNA methyltransferase inhibitor zebularine induces human cholangiocarcinoma cell death through alteration of DNA methylation status.Kazuaki Nakamura et al.PloS one, 10(3), e0120545-e0120545 (2015-03-24)
Promoter Methylation of Selected Genes in Non-Small-Cell Lung Cancer Patients and Cell Lines.Victoria Sarne et al.International journal of molecular sciences, 21(13) (2020-07-02)
Zebularine: a unique molecule for an epigenetically based strategy in cancer chemotherapy.Victor E Marquez et al.Annals of the New York Academy of Sciences, 1058, 246-254 (2006-01-06)
The reelin and GAD67 promoters are activated by epigenetic drugs that facilitate the disruption of local repressor complexes.Marija Kundakovic et al.Molecular pharmacology, 75(2), 342-354 (2008-11-26)
Different Schedule-Dependent Effects of Epigenetic Modifiers on Cytotoxicity by Anticancer Drugs in Colorectal Cancer Cells.Mika Hosokawa et al.Biological & pharmaceutical bulletin, 40(12), 2199-2204 (2017-09-29)
Creation of zebularine-resistant human cytidine deaminase mutants to enhance the chemoprotection of hematopoietic stem cells.Hongmei Ruan et al.Protein engineering, design & selection : PEDS, 29(12), 573-582 (2016-05-11)
Reactivation of hyperglycemia-induced hypocretin (HCRT) gene silencing by N-acetyl-d-mannosamine in the orexin neurons derived from human iPS cells.Koji Hayakawa et al.Epigenetics, 12(9), 764-778 (2017-08-02)
Zebularine induces replication-dependent double-strand breaks which are preferentially repaired by homologous recombination.Manuel Luis Orta et al.DNA repair, 57, 116-124 (2017-07-22)
Aberrant Retinoblastoma (RB)-E2F Transcriptional Regulation Defines Molecular Phenotypes of Osteosarcoma.Milcah C Scott et al.The Journal of biological chemistry, 290(47), 28070-28083 (2015-09-18)
Light signaling controls nuclear architecture reorganization during seedling establishment.Clara Bourbousse et al.Proceedings of the National Academy of Sciences of the United States of America, 112(21), E2836-E2844 (2015-05-13)
Telomere elongation upon transfer to callus culture reflects the reprogramming of telomere stability control in Arabidopsis.Pavla Polanská Sováková et al.Plant molecular biology, 98(1-2), 81-99 (2018-08-22)
The role of DNA methylation in the mechanisms of memory reconsolidation and development of amnesia.V P Nikitin et al.Behavioural brain research, 279, 148-154 (2014-12-03)
Zebularine: a unique molecule for an epigenetically based strategy in cancer chemotherapy. The magic of its chemistry and biology.Victor E Marquez et al.Nucleosides, nucleotides & nucleic acids, 24(5-7), 305-318 (2005-10-27)
Dnmts and Tet target memory-associated genes after appetitive olfactory training in honey bees.Stephanie D Biergans et al.Scientific reports, 5, 16223-16223 (2015-11-05)
First demonstration of olfactory learning and long-term memory in honey bee queens.Zhiwen Gong et al.The Journal of experimental biology, 221(Pt 14) (2018-05-20)
Zebularine-induced myeloma cell death is accompanied by decreased c-Myc expression.Patryk Krzeminski et al.Cellular oncology (Dordrecht), 43(4), 743-750 (2020-05-13)
Pyrimidinone: versatile Trojan horse in DNA photodamage?Mathias Micheel et al.Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology, 14(9), 1598-1606 (2015-07-15)
Zebularine significantly improves the preimplantation development of ovine somatic cell nuclear transfer embryos.Hui Cao et al.Reproduction, fertility, and development, 31(2), 357-365 (2018-09-11)
The potential of clofarabine in MLL-rearranged infant acute lymphoblastic leukaemia.Dominique J P M Stumpel et al.European journal of cancer (Oxford, England : 1990), 51(14), 2008-2021 (2015-07-21)
Neonatal Inhibition of DNA Methylation Alters Cell Phenotype in Sexually Dimorphic Regions of the Mouse Brain.Morgan Mosley et al.Endocrinology, 158(6), 1838-1848 (2017-04-12)
Prolonged febrile seizures induce inheritable memory deficits in rats through DNA methylation.Yun-Jian Dai et al.CNS neuroscience & therapeutics, 25(5), 601-611 (2019-01-23)
The SMC5/6 Complex Subunit NSE4A Is Involved in DNA Damage Repair and Seed Development.Mariana Díaz et al.The Plant cell, 31(7), 1579-1597 (2019-05-01)
Chromatin remodeling factor CHR18 interacts with replication protein RPA1A to regulate the DNA replication stress response in Arabidopsis.Jia-Jia Han et al.The New phytologist, 220(2), 476-487 (2018-07-06)
Hypomethylation of the aquatic invasive plant, Ludwigia grandiflora subsp. hexapetala mimics the adaptive transition into the terrestrial morphotype.Julien Genitoni et al.Physiologia plantarum, 170(2), 280-298 (2020-07-06)
Noradrenaline goes nuclear: epigenetic modifications during long-lasting synaptic potentiation triggered by activation of β-adrenergic receptors.Sabyasachi Maity et al.The Journal of physiology, 594(4), 863-881 (2015-11-18)
Zebularine Promotes Hepatic Differentiation of Rabbit Bone Marrow Mesenchymal Stem Cells by Interfering with p38 MAPK Signaling.Yong-Heng Luo et al.Stem cells international, 2018, 9612512-9612512 (2018-11-09)
Epigenetic inhibitor zebularine activates ear pinna wound closure in the mouse.Piotr Sass et al.EBioMedicine, 46, 317-329 (2019-07-16)
Zebularine: a new drug for epigenetic therapy.C B Yoo et al.Biochemical Society transactions, 32(Pt 6), 910-912 (2004-10-28)
Adenovirus assembly is impaired by BMI1-related histone deacetylase activity.Manli Na et al.Virology, 456-457, 227-237 (2014-06-04)
Epigenetic inheritance of circadian period in clonal cells.Yan Li et al.eLife, 9 (2020-05-28)
The Role of Epigenetic Alterations Involved in Sepsis: An Overview.Fatima Ismail Hassan et al.Current pharmaceutical design, 24(24), 2862-2869 (2018-09-05)
DNA Methylation Inhibitor Zebularine Confers Stroke Protection in Ischemic Rats.Hua Dock et al.Translational stroke research, 6(4), 296-300 (2015-04-01)
Inhibition of DNA Methylation With Zebularine Alters Lipopolysaccharide-Induced Sickness Behavior and Neuroinflammation in Mice.Stephanie M Matt et al.Frontiers in neuroscience, 12, 636-636 (2018-10-04)
Activation of SIRT6 by DNA hypomethylating agents and clinical consequences on combination therapy in leukemia.Hetty E Carraway et al.Scientific reports, 10(1), 10325-10325 (2020-06-27)
Within-plant heterogeneity in fecundity and herbivory induced by localized DNA hypomethylation in the perennial herb Helleborus foetidus.Carlos M Herrera et al.American journal of botany, 106(6), 798-806 (2019-06-04)
Neonatal Inhibition of DNA Methylation Disrupts Testosterone-Dependent Masculinization of Neurochemical Phenotype.Carla D Cisternas et al.Endocrinology, 161(1) (2019-11-20)
OCT4 maintains self-renewal and reverses senescence in human hair follicle mesenchymal stem cells through the downregulation of p21 by DNA methyltransferases.Yan Lu et al.Stem cell research & therapy, 10(1), 28-28 (2019-01-17)
Metabolic targeting of HIF-1α potentiates the therapeutic efficacy of oxaliplatin in colorectal cancer.Tzu-Tang Wei et al.Oncogene, 39(2), 414-427 (2019-09-04)
Dynamic regulation of H3K27 trimethylation during Arabidopsis differentiation.Marcel Lafos et al.PLoS genetics, 7(4), e1002040-e1002040 (2011-04-15)
Epidrug mediated re-expression of miRNA targeting the HMGA transcripts in pituitary cells.Mark O Kitchen et al.Pituitary, 18(5), 674-684 (2015-01-06)
An epigenetic screen unmasks metallothioneins as putative contributors to renal cell carcinogenesis.Imad Alkamal et al.Urologia internationalis, 94(1), 99-110 (2014-03-26)
Zebularine upregulates expression of CYP genes through inhibition of DNMT1 and PKR in HepG2 cells.Kazuaki Nakamura et al.Scientific reports, 7, 41093-41093 (2017-01-24)
Pharmacological Manipulation of DNA Methylation in Adult Female Rats Normalizes Behavioral Consequences of Early-Life Maltreatment.Samantha M Keller et al.Frontiers in behavioral neuroscience, 12, 126-126 (2018-07-17)
Inhibition of the HDAC/Suv39/G9a pathway restores the expression of DNA damage-dependent major histocompatibility complex class I-related chain A and B in cancer cells.Nakako Izumi Nakajima et al.Oncology reports, 38(2), 693-702 (2017-07-06)
Pan-Cancer Analysis Reveals the Functional Importance of Protein Lysine Modification in Cancer Development.Li Chen et al.Frontiers in genetics, 9, 254-254 (2018-08-02)
Cranial irradiation inhibits hippocampal neurogenesis via DNMT1 and DNMT3A.Shengjun Ji et al.Oncology letters, 15(3), 2899-2904 (2018-02-13)
Zebularine exerts its antiproliferative activity through S phase delay and cell death in human malignant mesothelioma cells.Yukitoshi Takemura et al.Bioscience, biotechnology, and biochemistry, 82(7), 1159-1164 (2018-04-25)
备注
Products protected by valid patents are not offered for sale in countries where the sale of such products constitutes a patent infringement and its liability is at buyer's risk.
Products currently covered by valid US Patents are offered for R&D use in accordance with 35 USC 271 +A13(1).
名称 | CAS号 |
---|

相关产品
相关资讯
问
热门标签
询 单
请 填 写 相 关 信 息
- 请填写产品名称!
- CAS号
- 请正确填写公司名称!
- 请正确填写联系人!
- 请正确填写联系电话!
- 请正确填写联系邮箱!
- 请描述您的问题!