
4-Chloro-1-methyl-3-(2-methylpropyl)-1H-pyrazolo[4,3-c]pyridine | CAS:1207175-16-3
4-Chloro-1-methyl-3-(2-methylpropyl)-1H-pyrazolo[4,3-c]pyridine
- 名称:4-氯-1-甲基-3-(2-甲基丙基)-1H-吡唑并[4,3-c]吡啶 | 4-Chloro-1-methyl-3-(2-methylpropyl)-1H-pyrazolo[4,3-c]pyridine
- CAS号:1207175-16-3
- 别名:
- 分子式:C11H14ClN3
- 分子量:223.70
- EINESC号:
产品描述
物理化学性质
密度 | 1.24 |
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Genistein enhances the efficacy of cabazitaxel chemotherapy in metastatic castration-resistant prostate cancer cells.Shumin Zhang et al.The Prostate, 73(15), 1681-1689 (2013-09-04)
Epigenetic alterations and decreasing insecticide sensitivity of the Asian tiger mosquito Aedes albopictus.A Oppold et al.Ecotoxicology and environmental safety, 122, 45-53 (2015-07-21)
Impact of induced fit on ligand binding to the androgen receptor: a multidimensional QSAR study to predict endocrine-disrupting effects of environmental chemicals.Markus A Lill et al.Journal of medicinal chemistry, 48(18), 5666-5674 (2005-09-02)
Effect of 7-difluoromethyl-5, 4'-dimethoxygenistein on aorta atherosclerosis in hyperlipidemia ApoE(-/-) mice induced by a cholesterol-rich diet.Yong Zhang et al.Drug design, development and therapy, 7, 233-242 (2013-04-17)
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Pleiotropic effects of genistein in metabolic, inflammatory, and malignant diseases.Ganji Purnachandra Nagaraju et al.Nutrition reviews, 71(8), 562-572 (2013-07-20)
Effect of flavonoids on androgen and glucocorticoid receptors based on in vitro reporter gene assay.Yosuke Nishizaki et al.Bioorganic & medicinal chemistry letters, 19(16), 4706-4710 (2009-07-14)
Antioxidant activity and anti-inflammatory activity of ethanol extract and fractions of Doenjang in LPS-stimulated RAW 264.7 macrophages.Chung Shil Kwak et al.Nutrition research and practice, 9(6), 569-578 (2015-12-04)
Phytoestrogens induce apoptosis through a mitochondria/caspase pathway in human breast cancer cells.F-P Chen et al.Climacteric : the journal of the International Menopause Society, 17(4), 385-392 (2013-12-05)
A chemical screen identifies small molecules that regulate hepcidin expression.Vera Gaun et al.Blood cells, molecules & diseases, 53(4), 231-240 (2014-07-08)
Isoflavones with unusually modified B-rings and their evaluation as antiproliferative agents.B Le S Tchize Ndejouong et al.Bioorganic & medicinal chemistry letters, 19(22), 6473-6476 (2009-10-13)
Subtle side-chain modifications of the hop phytoestrogen 8-prenylnaringenin result in distinct agonist/antagonist activity profiles for estrogen receptors alpha and beta.Frederik Roelens et al.Journal of medicinal chemistry, 49(25), 7357-7365 (2006-12-08)
Chemotaxonomic Metabolite Profiling of 62 Indigenous Plant Species and Its Correlation with Bioactivities.Sarah Lee et al.Molecules (Basel, Switzerland), 20(11), 19719-19734 (2015-11-06)
Exposure to genistein during gestation and lactation demasculinizes the reproductive system in rats.Amy B Wisniewski et al.The Journal of urology, 169(4), 1582-1586 (2003-03-12)
EGFR tyrosine kinase regulates human small-conductance Ca2+-activated K+ (hSKCa1) channels expressed in HEK-293 cells.Wei Wu et al.The Biochemical journal, 452(1), 121-129 (2013-03-19)
Genistein increases progesterone secretion by elevating related enzymes in chicken granulosa cells.Y Q Xiao et al.Poultry science, 98(4), 1911-1917 (2018-09-22)
Molecular genetics of naringenin biosynthesis, a typical plant secondary metabolite produced by Streptomyces clavuligerus.Rubén Álvarez-Álvarez et al.Microbial cell factories, 14, 178-178 (2015-11-11)
Reduced glutathione increases quercetin stimulatory effects on HDL- or apoA1-mediated cholesterol efflux from J774A.1 macrophages.M Rosenblat et al.Free radical research, 48(12), 1462-1472 (2014-09-11)
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The soy isoflavone, genistein, protects human cortical neuronal cells from oxidative stress.Manisha Sonee et al.Neurotoxicology, 25(5), 885-891 (2004-08-04)
High production of succinyl isoflavone glycosides by Bacillus licheniformis ZSP01 resting cells in aqueous miscible organic medium.Sen Zhang et al.Biotechnology and applied biochemistry, 62(2), 255-259 (2014-06-13)
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Cloning of oestrogen receptor beta from Old and New World primates: identification of splice variants and functional analysisSierens JE, et al. Journal of Molecular Endocrinology, 32(3), 703-718 (2004)
Urinary phytoestrogen levels related to idiopathic male infertility in Chinese men.Yankai Xia et al.Environment international, 59, 161-167 (2013-07-04)
Epigenetic alterations and decreasing insecticide sensitivity of the Asian tiger mosquito Aedes albopictus.A Oppold et al.Ecotoxicology and environmental safety, 122, 45-53 (2015-07-21)
Effect of 7-difluoromethyl-5, 4'-dimethoxygenistein on aorta atherosclerosis in hyperlipidemia ApoE(-/-) mice induced by a cholesterol-rich diet.Yong Zhang et al.Drug design, development and therapy, 7, 233-242 (2013-04-17)
Genistein and daidzein: different molecular effects on prostate cancer.Mawussi Adjakly et al.Anticancer research, 33(1), 39-44 (2012-12-26)
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Particle size influences fibronectin internalization and degradation by fibroblasts.Peter Bozavikov et al.Experimental cell research, 328(1), 172-185 (2014-07-06)
Intracellular distribution and biological effects of phytochemicals in a sex steroid- sensitive model of human prostate adenocarcinoma.Antonella Smeriglio et al.Anti-cancer agents in medicinal chemistry, 14(10), 1386-1396 (2014-06-26)
Genistein enhances the efficacy of cabazitaxel chemotherapy in metastatic castration-resistant prostate cancer cells.Shumin Zhang et al.The Prostate, 73(15), 1681-1689 (2013-09-04)
Asterolaurins A-F, xenicane diterpenoids from the Taiwanese soft coral Asterospicularia laurae.Yu-Chi Lin et al.Journal of natural products, 72(11), 1911-1916 (2009-10-30)
Impact of induced fit on ligand binding to the androgen receptor: a multidimensional QSAR study to predict endocrine-disrupting effects of environmental chemicals.Markus A Lill et al.Journal of medicinal chemistry, 48(18), 5666-5674 (2005-09-02)
Acute inhibition of the cystic fibrosis transmembrane conductance regulator (CFTR) Cl- channel by thyroid hormones involves multiple mechanisms.Zhiwei Cai et al.American journal of physiology. Cell physiology, 305(8), C817-C828 (2013-06-21)
Plasma Pharmacokinetics of Polyphenols in a Traditional Japanese Medicine, Jumihaidokuto, Which Suppresses Propionibacterium acnes-Induced Dermatitis in Rats.Takashi Matsumoto et al.Molecules (Basel, Switzerland), 20(10), 18031-18046 (2015-10-06)
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Azaphilones and p-terphenyls from the mangrove endophytic fungus Penicillium chermesinum (ZH4-E2) isolated from the South China Sea.Hongbo Huang et al.Journal of natural products, 74(5), 997-1002 (2011-04-23)
Effects of flavonoids on expression of genes involved in cell cycle regulation and DNA replication in human fibroblasts.Marta Moskot et al.Molecular and cellular biochemistry, 407(1-2), 97-109 (2015-05-25)
Adenylate Cyclase Toxin promotes bacterial internalisation into non phagocytic cells.César Martín et al.Scientific reports, 5, 13774-13774 (2015-09-09)
Genistein inhibits hepatocellular carcinoma cell migration by reversing the epithelial-mesenchymal transition: partial mediation by the transcription factor NFAT1.Weiqi Dai et al.Molecular carcinogenesis, 54(4), 301-311 (2013-11-19)
Modulatory effects of phytoestrogens on the expression of Fas ligand and the release of cytochrome C in normal and cancerous endometrial cells.Sutthasinee Poonyachoti et al.Journal of the Medical Association of Thailand = Chotmaihet thangphaet, 95 Suppl 12, S105-S112 (2013-03-22)
Synthesis of genistein derivatives and determination of their protective effects against vascular endothelial cell damages caused by hydrogen peroxide.Xiao-Hua Fu et al.Bioorganic & medicinal chemistry letters, 18(2), 513-517 (2007-12-11)
Metabolism of the soy isoflavones daidzein, genistein and glycitein in human subjects. Identification of new metabolites having an intact isoflavonoid skeleton.Satu Maarit Heinonen et al.The Journal of steroid biochemistry and molecular biology, 87(4-5), 285-299 (2003-12-31)
Fabrication of genistein-loaded biodegradable TPGS-b-PCL nanoparticles for improved therapeutic effects in cervical cancer cells.Hongling Zhang et al.International journal of nanomedicine, 10, 2461-2473 (2015-04-08)
Polyurethane Microstructures--a Good or Bad in vitro Partner for the Isoflavone Genistein?Corina Danciu et al.Natural product communications, 10(6), 951-954 (2015-07-23)
In vitro comparison of liposomal drug delivery systems targeting the oxytocin receptor: a potential novel treatment for obstetric complications.Susan Hua et al.International journal of nanomedicine, 14, 2191-2206 (2019-04-17)
Identification of urinary metabolites of the red clover isoflavones formononetin and biochanin A in human subjects.Satu-Maarit Heinonen et al.Journal of agricultural and food chemistry, 52(22), 6802-6809 (2004-10-28)
Sulfation of the isoflavones genistein and daidzein in human and rat liver and gastrointestinal tract.Martin J Ronis et al.Journal of medicinal food, 9(3), 348-355 (2006-09-29)
Autophagy-Lysosome Pathway in Renal Tubular Epithelial Cells Is Disrupted by Advanced Glycation End Products in Diabetic Nephropathy.Wei Jing Liu et al.The Journal of biological chemistry, 290(33), 20499-20510 (2015-06-24)
Carboxymethylated-kappa-casein: a convenient tool for the identification of polyphenolic inhibitors of amyloid fibril formation.John A Carver et al.Bioorganic & medicinal chemistry, 18(1), 222-228 (2009-11-26)
UHPLC-UV method for the determination of flavonoids in dietary supplements and for evaluation of their antioxidant activities.Sylwia Magiera et al.Journal of pharmaceutical and biomedical analysis, 102, 468-475 (2014-12-03)
Synthetic derivatives of genistein, their properties and possible applications.Aleksandra Rusin et al.Acta biochimica Polonica, 57(1), 23-34 (2010-03-11)
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Diarylheptanoids, new phytoestrogens from the rhizomes of Curcuma comosa: Isolation, chemical modification and estrogenic activity evaluation.Apichart Suksamrarn et al.Bioorganic & medicinal chemistry, 16(14), 6891-6902 (2008-06-17)
Molecular genetics of naringenin biosynthesis, a typical plant secondary metabolite produced by Streptomyces clavuligerus.Rubén Álvarez-Álvarez et al.Microbial cell factories, 14, 178-178 (2015-11-11)
Genistein inhibits hepatocellular carcinoma cell migration by reversing the epithelial-mesenchymal transition: partial mediation by the transcription factor NFAT1.Weiqi Dai et al.Molecular carcinogenesis, 54(4), 301-311 (2013-11-19)
Isoflavones with unusually modified B-rings and their evaluation as antiproliferative agents.B Le S Tchize Ndejouong et al.Bioorganic & medicinal chemistry letters, 19(22), 6473-6476 (2009-10-13)
The soy isoflavone, genistein, protects human cortical neuronal cells from oxidative stress.Manisha Sonee et al.Neurotoxicology, 25(5), 885-891 (2004-08-04)
Effect of flavonoids on androgen and glucocorticoid receptors based on in vitro reporter gene assay.Yosuke Nishizaki et al.Bioorganic & medicinal chemistry letters, 19(16), 4706-4710 (2009-07-14)
Antioxidant activity and anti-inflammatory activity of ethanol extract and fractions of Doenjang in LPS-stimulated RAW 264.7 macrophages.Chung Shil Kwak et al.Nutrition research and practice, 9(6), 569-578 (2015-12-04)
Phytoestrogens induce apoptosis through a mitochondria/caspase pathway in human breast cancer cells.F-P Chen et al.Climacteric : the journal of the International Menopause Society, 17(4), 385-392 (2013-12-05)
Pleiotropic effects of genistein in metabolic, inflammatory, and malignant diseases.Ganji Purnachandra Nagaraju et al.Nutrition reviews, 71(8), 562-572 (2013-07-20)
A chemical screen identifies small molecules that regulate hepcidin expression.Vera Gaun et al.Blood cells, molecules & diseases, 53(4), 231-240 (2014-07-08)
Exposure to genistein during gestation and lactation demasculinizes the reproductive system in rats.Amy B Wisniewski et al.The Journal of urology, 169(4), 1582-1586 (2003-03-12)
Genistein supplementation increases bone turnover but does not prevent alcohol-induced bone loss in male mice.Carrie S Yang et al.Experimental biology and medicine (Maywood, N.J.), 239(10), 1380-1389 (2014-05-30)
Genistein increases estrogen receptor beta expression in prostate cancer via reducing its promoter methylation.Abeer M Mahmoud et al.The Journal of steroid biochemistry and molecular biology, 152, 62-75 (2015-05-02)
Murine norovirus replication induces G0/G1 cell cycle arrest in asynchronously growing cells.Colin Davies et al.Journal of virology, 89(11), 6057-6066 (2015-03-27)
Effect of the isoflavone genistein on tumor size, metastasis potential and melanization in a B16 mouse model of murine melanoma.Corina Danciu et al.Natural product communications, 8(3), 343-346 (2013-05-18)
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Adenylate Cyclase Toxin promotes bacterial internalisation into non phagocytic cells.César Martín et al.Scientific reports, 5, 13774-13774 (2015-09-09)
EGFR tyrosine kinase regulates human small-conductance Ca2+-activated K+ (hSKCa1) channels expressed in HEK-293 cells.Wei Wu et al.The Biochemical journal, 452(1), 121-129 (2013-03-19)
Subtle side-chain modifications of the hop phytoestrogen 8-prenylnaringenin result in distinct agonist/antagonist activity profiles for estrogen receptors alpha and beta.Frederik Roelens et al.Journal of medicinal chemistry, 49(25), 7357-7365 (2006-12-08)
Genistein increases progesterone secretion by elevating related enzymes in chicken granulosa cells.Y Q Xiao et al.Poultry science, 98(4), 1911-1917 (2018-09-22)
[Chemical constituents from cell cultures of Morus alba].Xiao-Yu Tao et al.Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, 37(24), 3738-3742 (2013-05-01)
Natural ortho-dihydroxyisoflavone derivatives from aged Korean fermented soybean paste as potent tyrosinase and melanin formation inhibitors.Jun-Seong Park et al.Bioorganic & medicinal chemistry letters, 20(3), 1162-1164 (2009-12-22)
UHPLC-UV method for the determination of flavonoids in dietary supplements and for evaluation of their antioxidant activities.Sylwia Magiera et al.Journal of pharmaceutical and biomedical analysis, 102, 468-475 (2014-12-03)
Synthesis and characterization of 3-arylquinazolinone and 3-arylquinazolinethione derivatives as selective estrogen receptor beta modulators.Timur Güngör et al.Journal of medicinal chemistry, 49(8), 2440-2455 (2006-04-14)
Fabrication of genistein-loaded biodegradable TPGS-b-PCL nanoparticles for improved therapeutic effects in cervical cancer cells.Hongling Zhang et al.International journal of nanomedicine, 10, 2461-2473 (2015-04-08)
Daucane sesquiterpenes from Ferula hermonis.Amélie Lhuillier et al.Journal of natural products, 68(3), 468-471 (2005-03-25)
Polyurethane Microstructures--a Good or Bad in vitro Partner for the Isoflavone Genistein?Corina Danciu et al.Natural product communications, 10(6), 951-954 (2015-07-23)
In vitro comparison of liposomal drug delivery systems targeting the oxytocin receptor: a potential novel treatment for obstetric complications.Susan Hua et al.International journal of nanomedicine, 14, 2191-2206 (2019-04-17)
Identification of urinary metabolites of the red clover isoflavones formononetin and biochanin A in human subjects.Satu-Maarit Heinonen et al.Journal of agricultural and food chemistry, 52(22), 6802-6809 (2004-10-28)
[Genistein in chemoprevention and treatment].Michał Tarkowski et al.Polski merkuriusz lekarski : organ Polskiego Towarzystwa Lekarskiego, 34(199), 54-57 (2013-03-16)
In-silico fragment-based identification of novel angiogenesis inhibitors.Sivanesan Dakshanamurthy et al.Bioorganic & medicinal chemistry letters, 17(16), 4551-4556 (2007-06-27)
Synthesis, crystal structure and antimicrobial activity of deoxybenzoin derivatives from genistein.Huan-Qiu Li et al.European journal of medicinal chemistry, 43(3), 662-667 (2007-07-13)
Human monocyte response to S-nitrosoglutathione-loaded nanoparticles: uptake, viability, and transcriptome.Ramia Safar et al.Molecular pharmaceutics, 12(2), 554-561 (2014-12-24)
Genistein inhibits p38 map kinase activation, matrix metalloproteinase type 2, and cell invasion in human prostate epithelial cells.Xiaoke Huang et al.Cancer research, 65(8), 3470-3478 (2005-04-19)
Metabolomics Reveals that Dietary Xenoestrogens Alter Cellular Metabolism Induced by Palbociclib/Letrozole Combination Cancer Therapy.Benedikt Warth et al.Cell chemical biology, 25(3), 291-300 (2018-01-18)
A novel UHPLC method for the rapid and simultaneous determination of daidzein, genistein and equol in human urine.Begoña Redruello et al.Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 1005, 1-8 (2015-10-08)
Synthesis of genistein derivatives and determination of their protective effects against vascular endothelial cell damages caused by hydrogen peroxide.Xiao-Hua Fu et al.Bioorganic & medicinal chemistry letters, 18(2), 513-517 (2007-12-11)
Metabolism of the soy isoflavones daidzein, genistein and glycitein in human subjects. Identification of new metabolites having an intact isoflavonoid skeleton.Satu Maarit Heinonen et al.The Journal of steroid biochemistry and molecular biology, 87(4-5), 285-299 (2003-12-31)
Reduced histone deacetylase 7 activity restores function to misfolded CFTR in cystic fibrosis.Darren M Hutt et al.Nature chemical biology, 6(1), 25-33 (2009-12-08)
Constituents of Dalbergia sissoo Roxb. leaves with osteogenic activity.Preety Dixit et al.Bioorganic & medicinal chemistry letters, 22(2), 890-897 (2012-01-04)
Effect of cigarette smoke condensate on gene promoter methylation in human lung cells.Lascelles Lyn-Cook et al.Tobacco induced diseases, 12(1), 15-15 (2014-09-13)
Genistein Induces Adipogenic and Autophagic Effects in Rainbow Trout (Oncorhynchus mykiss) Adipose Tissue: In Vitro and In Vivo Models.Sara Balbuena-Pecino et al.International journal of molecular sciences, 21(16) (2020-08-23)
Kallistatin treatment attenuates lethality and organ injury in mouse models of established sepsis.Pengfei Li et al.Critical care (London, England), 19, 200-200 (2015-05-02)
Role of protein tyrosine kinase in the effect of IP6 on IL-8 secretion in intestinal epithelial cells.Joanna Wawszczyk et al.Acta poloniae pharmaceutica, 70(1), 79-86 (2013-04-25)
Estrogen receptor beta selective ligands: discovery and SAR of novel heterocyclic ligands.Richard Chesworth et al.Bioorganic & medicinal chemistry letters, 15(24), 5562-5566 (2005-10-13)
Direct cellular delivery of human proteasomes to delay tau aggregation.Dong Hoon Han et al.Nature communications, 5, 5633-5633 (2014-12-06)
Fluorinated ΔF508-CFTR correctors and potentiators for PET imaging.Holly R Davison et al.Bioorganic & medicinal chemistry letters, 22(4), 1602-1605 (2012-01-28)
Isoflavonoids and other compounds from Psorothamnus arborescens with antiprotozoal activities.Manar M Salem et al.Journal of natural products, 69(1), 43-49 (2006-01-31)
Genistein inhibits p38 map kinase activation, matrix metalloproteinase type 2, and cell invasion in human prostate epithelial cells.Xiaoke Huang et al.Cancer research, 65(8), 3470-3478 (2005-04-19)
Genistein Induces Adipogenic and Autophagic Effects in Rainbow Trout (Oncorhynchus mykiss) Adipose Tissue: In Vitro and In Vivo Models.Sara Balbuena-Pecino et al.International journal of molecular sciences, 21(16) (2020-08-23)
Kallistatin treatment attenuates lethality and organ injury in mouse models of established sepsis.Pengfei Li et al.Critical care (London, England), 19, 200-200 (2015-05-02)
Role of protein tyrosine kinase in the effect of IP6 on IL-8 secretion in intestinal epithelial cells.Joanna Wawszczyk et al.Acta poloniae pharmaceutica, 70(1), 79-86 (2013-04-25)
Effect of Genistein on vasculogenic mimicry formation by human uveal melanoma cells.Rihong Cong et al.Journal of experimental & clinical cancer research : CR, 28, 124-124 (2009-09-09)
Direct cellular delivery of human proteasomes to delay tau aggregation.Dong Hoon Han et al.Nature communications, 5, 5633-5633 (2014-12-06)
Fluorinated ΔF508-CFTR correctors and potentiators for PET imaging.Holly R Davison et al.Bioorganic & medicinal chemistry letters, 22(4), 1602-1605 (2012-01-28)
Natural ortho-dihydroxyisoflavone derivatives from aged Korean fermented soybean paste as potent tyrosinase and melanin formation inhibitors.Jun-Seong Park et al.Bioorganic & medicinal chemistry letters, 20(3), 1162-1164 (2009-12-22)
Estrogen receptor beta selective ligands: discovery and SAR of novel heterocyclic ligands.Richard Chesworth et al.Bioorganic & medicinal chemistry letters, 15(24), 5562-5566 (2005-10-13)
Constituents of Dalbergia sissoo Roxb. leaves with osteogenic activity.Preety Dixit et al.Bioorganic & medicinal chemistry letters, 22(2), 890-897 (2012-01-04)
Molecular effects of ER alpha- and beta-selective agonists on regulation of energy homeostasis in obese female Wistar rats.Carmen Weigt et al.Molecular and cellular endocrinology, 377(1-2), 147-158 (2013-07-23)
An efficient and economical MTT assay for determining the antioxidant activity of plant natural product extracts and pure compounds.Yunbao Liu et al.Journal of natural products, 73(7), 1193-1195 (2010-06-23)
Metabolomic fingerprinting of saffron by LC/MS: novel authenticity markers.Miguel Guijarro-Díez et al.Analytical and bioanalytical chemistry, 407(23), 7197-7213 (2015-07-23)
Reduced histone deacetylase 7 activity restores function to misfolded CFTR in cystic fibrosis.Darren M Hutt et al.Nature chemical biology, 6(1), 25-33 (2009-12-08)
Effect of cigarette smoke condensate on gene promoter methylation in human lung cells.Lascelles Lyn-Cook et al.Tobacco induced diseases, 12(1), 15-15 (2014-09-13)
Quantitative determination of acetyl glucoside isoflavones and their metabolites in human urine using combined liquid chromatography-mass spectrometry.Lijuan Chen et al.Journal of chromatography. A, 1154(1-2), 103-110 (2007-05-15)
Phenolic constituents of the rhizomes of the Thai medicinal plant Belamcanda chinensis with proliferative activity for two breast cancer cell lines.Orawan Monthakantirat et al.Journal of natural products, 68(3), 361-364 (2005-03-25)
Genistein downregulates onco-miR-1260b and inhibits Wnt-signalling in renal cancer cells.H Hirata et al.British journal of cancer, 108(10), 2070-2078 (2013-04-18)
HIV-1 latency in actively dividing human T cell lines.Rienk E Jeeninga et al.Retrovirology, 5, 37-37 (2008-04-29)
Design, characterization, and in vitro cellular inhibition and uptake of optimized genistein-loaded NLC for the prevention of posterior capsular opacification using response surface methodology.Wenji Zhang et al.International journal of pharmaceutics, 454(1), 354-366 (2013-07-24)
Synthesis, crystal structure and antimicrobial activity of deoxybenzoin derivatives from genistein.Huan-Qiu Li et al.European journal of medicinal chemistry, 43(3), 662-667 (2007-07-13)
Metabolomics Reveals that Dietary Xenoestrogens Alter Cellular Metabolism Induced by Palbociclib/Letrozole Combination Cancer Therapy.Benedikt Warth et al.Cell chemical biology, 25(3), 291-300 (2018-01-18)
Biophysical characterization of genistein-membrane interaction and its correlation with biological effect on cells - The case of EYPC liposomes and human erythrocyte membranes.Bożena Pawlikowska-Pawlęga et al.Biochimica et biophysica acta, 1838(8), 2127-2138 (2014-05-13)
Modification of Prenylated Stilbenoids in Peanut (Arachis hypogaea) Seedlings by the Same Fungi That Elicited Them: The Fungus Strikes Back.Siti Aisyah et al.Journal of agricultural and food chemistry, 63(42), 9260-9268 (2015-10-16)
Genetic Inhibition Of The Ubiquitin Ligase Rnf5 Attenuates Phenotypes Associated To F508del Cystic Fibrosis Mutation.Valeria Tomati et al.Scientific reports, 5, 12138-12138 (2015-07-18)
Endothelial cell heparanase taken up by cardiomyocytes regulates lipoprotein lipase transfer to the coronary lumen after diabetes.Ying Wang et al.Diabetes, 63(8), 2643-2655 (2014-03-13)
Transcription factor cyclic adenosine monophosphate responsive element binding protein negatively regulates tumor necrosis factor alpha-induced protein 1 expression.Ning Liu et al.Molecular medicine reports, 12(5), 7763-7769 (2015-09-24)
Simultaneous determination of isoflavones and resveratrols for adulteration detection of soybean and peanut oils by mixed-mode SPE LC-MS/MS.Xin Zhao et al.Food chemistry, 176, 465-471 (2015-01-28)
Tuning the buffering capacity of polyethylenimine with glycerol molecules for efficient gene delivery: staying in or out of the endosomes.Bijay Singh et al.Macromolecular bioscience, 15(5), 622-635 (2015-01-13)
In vitro investigation of antioxidant, anti-Inflammatory, and antiplatelet adhesion properties of genistein-modified poly(ethersulfone)/poly(vinylpyrrolidone) hemodialysis membranes.Teng Chang et al.Journal of biomedical materials research. Part B, Applied biomaterials, 103(3), 539-547 (2014-06-18)
Phytochemicals perturb membranes and promiscuously alter protein function.Helgi I Ingólfsson et al.ACS chemical biology, 9(8), 1788-1798 (2014-06-06)
Modification of Prenylated Stilbenoids in Peanut (Arachis hypogaea) Seedlings by the Same Fungi That Elicited Them: The Fungus Strikes Back.Siti Aisyah et al.Journal of agricultural and food chemistry, 63(42), 9260-9268 (2015-10-16)
Genetic Inhibition Of The Ubiquitin Ligase Rnf5 Attenuates Phenotypes Associated To F508del Cystic Fibrosis Mutation.Valeria Tomati et al.Scientific reports, 5, 12138-12138 (2015-07-18)
Identifying off-target effects and hidden phenotypes of drugs in human cells.Marnie L MacDonald et al.Nature chemical biology, 2(6), 329-337 (2006-05-09)
Biophysical characterization of genistein-membrane interaction and its correlation with biological effect on cells - The case of EYPC liposomes and human erythrocyte membranes.Bożena Pawlikowska-Pawlęga et al.Biochimica et biophysica acta, 1838(8), 2127-2138 (2014-05-13)
Endothelial cell heparanase taken up by cardiomyocytes regulates lipoprotein lipase transfer to the coronary lumen after diabetes.Ying Wang et al.Diabetes, 63(8), 2643-2655 (2014-03-13)
Transcription factor cyclic adenosine monophosphate responsive element binding protein negatively regulates tumor necrosis factor alpha-induced protein 1 expression.Ning Liu et al.Molecular medicine reports, 12(5), 7763-7769 (2015-09-24)
Simultaneous determination of isoflavones and resveratrols for adulteration detection of soybean and peanut oils by mixed-mode SPE LC-MS/MS.Xin Zhao et al.Food chemistry, 176, 465-471 (2015-01-28)
Tuning the buffering capacity of polyethylenimine with glycerol molecules for efficient gene delivery: staying in or out of the endosomes.Bijay Singh et al.Macromolecular bioscience, 15(5), 622-635 (2015-01-13)
Anti-inflammatory effects of genistein via suppression of the toll-like receptor 4-mediated signaling pathway in lipopolysaccharide-stimulated BV2 microglia.Jin-Woo Jeong et al.Chemico-biological interactions, 212, 30-39 (2014-02-05)
ERbeta ligands. Part 5: synthesis and structure-activity relationships of a series of 4'-hydroxyphenyl-aryl-carbaldehyde oxime derivatives.Richard E Mewshaw et al.Bioorganic & medicinal chemistry letters, 17(4), 902-906 (2006-12-26)
Reliability of bond dissociation enthalpy calculated by the PM6 method and experimental TEAC values in antiradical QSAR of flavonoids.Dragan Amić et al.Bioorganic & medicinal chemistry, 18(1), 28-35 (2009-12-01)
Chemoenzymatic syntheses of prenylated aromatic small molecules using Streptomyces prenyltransferases with relaxed substrate specificities.Takuto Kumano et al.Bioorganic & medicinal chemistry, 16(17), 8117-8126 (2008-08-07)
Autophagy-lysosome pathway in renal tubular epithelial cells is disrupted by advanced glycation end products in diabetic nephropathyLiu WJ, et al. The Journal of Biological Chemistry, jbc-M115 (2015)
Association between precocious puberty and some endocrine disruptors in human plasma.Taewoo Yum et al.Journal of environmental science and health. Part A, Toxic/hazardous substances & environmental engineering, 48(8), 912-917 (2013-03-15)
Resveratrol and genistein inhibition of rat isolated gastrointestinal contractions and related mechanisms.Li-Xue Zhang et al.World journal of gastroenterology, 20(41), 15335-15342 (2014-11-12)
Antileukemic activity of genistein, a major isoflavone present in soy products.Noël J-M Raynal et al.Journal of natural products, 71(1), 3-7 (2008-01-01)
17β-Estradiol and genistein acute treatments improve some cerebral cortex homeostasis aspects deteriorated by aging in female rats.Javier Morán et al.Experimental gerontology, 48(4), 414-421 (2013-02-20)
Frajunolides E-K, briarane diterpenes from Junceella fragilis.Chia-Ching Liaw et al.Journal of natural products, 71(9), 1551-1556 (2008-09-09)
Genista sessilifolia DC. extracts induce apoptosis across a range of cancer cell lines.P Bontempo et al.Cell proliferation, 46(2), 183-192 (2013-03-21)
Genistein downregulates onco-miR-1260b and inhibits Wnt-signalling in renal cancer cells.H Hirata et al.British journal of cancer, 108(10), 2070-2078 (2013-04-18)
The HPV16 and MusPV1 papillomaviruses initially interact with distinct host components on the basement membrane.Patricia M Day et al.Virology, 481, 79-94 (2015-03-17)
QSAR study of flavonoids and biflavonoids as influenza H1N1 virus neuraminidase inhibitors.Andrew G Mercader et al.European journal of medicinal chemistry, 45(5), 1724-1730 (2010-02-02)
Inhibitory effect of phloretin and biochanin A on IgE-mediated allergic responses in rat basophilic leukemia RBL-2H3 cells.Mi Ja Chung et al.Life sciences, 93(9-11), 401-408 (2013-08-03)
Genistein inhibits rotavirus replication and upregulates AQP4 expression in rotavirus-infected Caco-2 cells.Haohai Huang et al.Archives of virology, 160(6), 1421-1433 (2015-04-17)
Discovery of nonsteroidal 17beta-hydroxysteroid dehydrogenase 1 inhibitors by pharmacophore-based screening of virtual compound libraries.Daniela Schuster et al.Journal of medicinal chemistry, 51(14), 4188-4199 (2008-06-07)
Bioavailability and pharmacokinetics of genistein: mechanistic studies on its ADME.Zhen Yang et al.Anti-cancer agents in medicinal chemistry, 12(10), 1264-1280 (2012-05-16)
Docking and 3D-QSAR (quantitative structure activity relationship) studies of flavones, the potent inhibitors of p-glycoprotein targeting the nucleotide binding domain.Gugan Kothandan et al.European journal of medicinal chemistry, 46(9), 4078-4088 (2011-07-05)
In vitro investigation of antioxidant, anti-Inflammatory, and antiplatelet adhesion properties of genistein-modified poly(ethersulfone)/poly(vinylpyrrolidone) hemodialysis membranes.Teng Chang et al.Journal of biomedical materials research. Part B, Applied biomaterials, 103(3), 539-547 (2014-06-18)
Design, characterization, and in vitro cellular inhibition and uptake of optimized genistein-loaded NLC for the prevention of posterior capsular opacification using response surface methodology.Wenji Zhang et al.International journal of pharmaceutics, 454(1), 354-366 (2013-07-24)
Protective effects of germinated and fermented soybean extract against tert-butyl hydroperoxide-induced hepatotoxicity in HepG2 cells and in rats.Eun Young Kim et al.Food & function, 6(11), 3512-3521 (2015-08-25)
Fhit regulates EMT targets through an EGFR/Src/ERK/Slug signaling axis in human bronchial cells.Audrey Joannes et al.Molecular cancer research : MCR, 12(5), 775-783 (2014-01-28)
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