Primaquine diphosphate | CAS:63-45-6
Primaquine diphosphate
- 名称:磷酸伯安喹; N4-(6-甲氧基-8-喹啉基)-1-戊二胺二磷酸盐 | Primaquine diphosphate
- CAS号:63-45-6
- 别名:Primaquine bisphosphate; 8-(4-Amino-1-methylbutylamino)-6-methoxyquinoline diphosphate
- 分子式:C15H21N3O.2(H3PO4)
- 分子量:455.34
- EINESC号:200-560-8
产品描述
物理化学性质
熔点 | 199-205 ºC |
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水溶性 | moderately 溶解 |
安全数据
危险品标志 | T |
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危险类别码 | R25 |
安全说明书 | S45 |
SDS
来源 | SDS样本 |
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没有数据 | 没有数据 |
产品合成路线
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Reengineering rate-limiting, millisecond enzyme motions by introduction of an unnatural amino acid.Eric D Watt et al.Biophysical journal, 101(2), 411-420 (2011-07-20)
Intramolecular proton shuttle supports not only catalytic but also noncatalytic function of carbonic anhydrase II.Holger M Becker et al.Proceedings of the National Academy of Sciences of the United States of America, 108(7), 3071-3076 (2011-02-02)
Effects of 4-methylimidazole on cerebral glutamate decarboxylase activity and specific GABA receptor binding in mice.Tore Sivertsen et al.Toxicology mechanisms and methods, 19(3), 214-218 (2009-09-05)
Simultaneous quantitation of 2-acetyl-4-tetrahydroxybutylimidazole, 2- and 4-methylimidazoles, and 5-hydroxymethylfurfural in beverages by ultrahigh-performance liquid chromatography-tandem mass spectrometry.Jinyuan Wang et al.Journal of agricultural and food chemistry, 60(4), 917-921 (2012-01-10)
A DFT study of the 67Zn, 14N and 2H electric field gradient tensors in Zinc(II)-4-MeIm complexes and extrapolation to superoxide dismutase.S Javadian et al.Journal of molecular graphics & modelling, 27(5), 620-627 (2008-12-03)
Formation of carcinogenic 4(5)-methylimidazole in caramel model systems: a role of sulphite.Kwang-Geun Lee et al.Food chemistry, 136(3-4), 1165-1168 (2012-12-01)
Carcinogenicity and regulation of caramel colorings.Michael F Jacobson International journal of occupational and environmental health, 18(3), 254-259 (2012-10-03)
Completely N1-selective palladium-catalyzed arylation of unsymmetric imidazoles: application to the synthesis of nilotinib.Satoshi Ueda et al.Journal of the American Chemical Society, 134(1), 700-706 (2011-12-01)
Proton transfer from exogenous donors in catalysis by human carbonic anhydrase II.Ileana Elder et al.Archives of biochemistry and biophysics, 437(1), 106-114 (2005-04-12)
Three-dimensional networks in bis(imidazolium) 2,2'-dithiodibenzoate and 4-methylimidazolium 2-[(2-carboxyphenyl)disulfanyl]benzoate.Linheng Wei et al.Acta crystallographica. Section C, Crystal structure communications, 65(Pt 9), o453-o456 (2009-09-04)
Rapid chemiluminescent sandwich enzyme immunoassay capable of consecutively quantifying multiple tumor markers in a sample.Julie Kim et al.Talanta, 129, 106-112 (2014-08-17)
Quantification of short chain amines in aqueous matrices using liquid chromatography electrospray ionization tandem mass spectrometry.Jyrki Viidanoja Journal of chromatography. A, 1480, 106-111 (2016-12-21)
Induction of thyroid lesions in 14-week toxicity studies of 2 and 4-methylimidazole in Fischer 344/N rats and B6C3F1 mice.Po Chan et al.Archives of toxicology, 80(3), 169-180 (2005-09-24)
Protonation and hydrogen-bonding state of the distal histidine in the CO complex of horseradish peroxidase as studied by ultraviolet resonance Raman spectroscopy.Shinji Hashimoto et al.Biochemistry, 45(32), 9660-9667 (2006-08-09)
Toxicity and carcinogenicity studies of 4-methylimidazole in F344/N rats and B6C3F1 mice.P C Chan et al.Archives of toxicology, 82(1), 45-53 (2007-07-11)
Structures of human cytochrome P-450 2E1. Insights into the binding of inhibitors and both small molecular weight and fatty acid substrates.Patrick R Porubsky et al.The Journal of biological chemistry, 283(48), 33698-33707 (2008-09-27)
Comparative analysis of mutant tyrosine kinase chemical rescue.Kathryn E Muratore et al.Biochemistry, 48(15), 3378-3386 (2009-03-06)
Toxicology and carcinogenesis studies of 4-methylimidazole (Cas No. 822-36-6) in F344/N rats and B6C3F1 mice (feed studies). National Toxicology Program technical report series, (535)(535), 1-274 (2007-03-08)
The WNT/β-catenin pathway is a transcriptional regulator of CYP2E1, CYP1A2, and aryl hydrocarbon receptor gene expression in primary human hepatocytes.Sabine Gerbal-Chaloin et al.Molecular pharmacology, 86(6), 624-634 (2014-09-18)
Gas chromatographic-mass spectrometric quantification of 4-(5-)methylimidazole in roasted coffee after ion-pair extraction.S Casal et al.Journal of chromatography. A, 976(1-2), 285-291 (2002-12-05)
Does 4-methylimidazole have tumor preventive activity in the rat?F Jay Murray Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 49(1), 320-322 (2010-11-16)
Proton transfer pathways in the mutant His-64-Ala of human carbonic anhydrase II.Arijit Roy et al.Biopolymers, 82(6), 623-630 (2006-03-25)
Supercritical fluid extraction (SFE) of 4(5)-methylimidazole (4-MeI) and 2-acetyl-4(5)-(1,2,3,4)-tetrahydroxybutyl-imidazole (THI) from ground-coffee with high-performance liquid chromatographic-electrospray mass spectrometric quantification (HPLC/ESI-MS).L Lojková et al.Food additives and contaminants, 23(10), 963-973 (2006-09-20)
Determination of 4(5)-methylimidazole in soy sauce and other foods by LC-MS/MS after solid-phase extraction.Hitomi Yamaguchi et al.Journal of agricultural and food chemistry, 59(18), 9770-9775 (2011-09-02)
Quantification of 4-methylimidazole in class III and IV caramel colors: validation of a new method based on heart-cutting two-dimensional liquid chromatography (LC-LC).Cédric Moretton et al.Journal of agricultural and food chemistry, 59(8), 3544-3550 (2011-03-09)
Formation of carcinogenic 4(5)-methylimidazole in Maillard reaction systems.Joon-Kwan Moon et al.Journal of agricultural and food chemistry, 59(2), 615-618 (2010-12-29)
Determination of 4(5)-methylimidazole in carbonated beverages by isotope-dilution liquid chromatography-tandem mass spectrometry.Geemitha Ratnayake et al.Food additives & contaminants. Part A, Chemistry, analysis, control, exposure & risk assessment, 32(7), 1075-1082 (2015-05-23)
Carcinogenic 4(5)-methylimidazole found in beverages, sauces, and caramel colors: chemical properties, analysis, and biological activities.Matt Hengel et al.Journal of agricultural and food chemistry, 61(4), 780-789 (2013-01-09)
Microfluidic device capable of sensing ultrafast chemiluminescence.Young-Teck Kim et al.Talanta, 78(3), 998-1003 (2009-03-10)
Different protonation equilibria of 4-methylimidazole and acetic acid.Wei Gu et al.Chemphyschem : a European journal of chemical physics and physical chemistry, 8(17), 2445-2451 (2007-10-27)
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Products currently covered by valid US Patents are offered for R&D use in accordance with 35 USC 271 +A13(1).
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