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1,1,1-Tris(hydroxymethyl)ethane | CAS:77-85-0
1,1,1-Tris(hydroxymethyl)ethane
  • 名称:1,1,1-三(羟甲基)乙烷; 2-羟甲基-2-甲基-1,3-丙二醇; 三羟甲基乙烷 | 1,1,1-Tris(hydroxymethyl)ethane
  • CAS号:77-85-0
  • 别名:1,1,1-Trimethanolethane; 2-(Hydroxymethyl)-2-methyl-1,3-propanediol; Trimethylolethane
  • 分子式:C5H12O3
  • 分子量:120.15
  • EINESC号:201-063-9

产品描述

物理化学性质

熔点 200-203 ºC
水溶性 溶解

安全数据

安全说明书 S24/25

SDS

来源 SDS样本
没有数据没有数据
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Prostatic acid phosphatase is required for the antinociceptive effects of thiamine and benfotiamine.Julie K Hurt et al.PloS one, 7(10), e48562-e48562 (2012-11-03) Long-Term Cognitive Improvement After Benfotiamine Administration in Patients with Alzheimer's Disease.Xiaoli Pan et al.Neuroscience bulletin, 32(6), 591-596 (2016-10-04) PP2A contributes to endothelial death in high glucose: inhibition by benfotiamine.Y Du et al.American journal of physiology. Regulatory, integrative and comparative physiology, 299(6), R1610-R1617 (2010-10-01) Protective role of benfotiamine, a fat-soluble vitamin B1 analogue, in lipopolysaccharide-induced cytotoxic signals in murine macrophages.Umesh C S Yadav et al.Free radical biology & medicine, 48(10), 1423-1434 (2010-03-12) Benfotiamine, a synthetic S-acyl thiamine derivative, has different mechanisms of action and a different pharmacological profile than lipid-soluble thiamine disulfide derivatives.Marie-Laure Volvert et al.BMC pharmacology, 8, 10-10 (2008-06-14) A double-blind, randomized, placebo-controlled clinical trial on benfotiamine treatment in patients with diabetic nephropathy.Alaa Alkhalaf et al.Diabetes care, 33(7), 1598-1601 (2010-04-24) Benfotiamine improves functional recovery of the infarcted heart via activation of pro-survival G6PD/Akt signaling pathway and modulation of neurohormonal response.Rajesh Katare et al.Journal of molecular and cellular cardiology, 49(4), 625-638 (2010-06-15) The multifaceted therapeutic potential of benfotiamine.Pitchai Balakumar et al.Pharmacological research, 61(6), 482-488 (2010-03-02) Human pericyte-endothelial cell interactions in co-culture models mimicking the diabetic retinal microvascular environment.Sonia Tarallo et al.Acta diabetologica, 49 Suppl 1, S141-S151 (2012-04-25) Inhibition of macrophage oxidative stress prevents the reduction of ABCA-1 transporter induced by advanced glycated albumin.Raphael de Souza Pinto et al.Lipids, 47(5), 443-450 (2012-01-25) [Cochleovestibular disorders: approaches to diagnostics and treatment].O V Zaĭtseva Vestnik otorinolaringologii, (5)(5), 55-58 (2012-02-16) [The role of neurotropic therapy in the treatment of acute sensorineural impairment of hearing following a viral infection].A G Atanesian et al.Vestnik otorinolaringologii, (5)(5), 52-54 (2012-12-20) d-Ribose as a Contributor to Glycated Haemoglobin.Xixi Chen et al.EBioMedicine, 25, 143-153 (2017-10-17) Pine bark (Pinus spp.) extract for treating chronic disorders.Nina U Robertson et al.The Cochrane database of systematic reviews, 9, CD008294-CD008294 (2020-09-30) The effect of benfotiamine on mu-opioid receptor mediated antinociception in experimental diabetes.C Nacitarhan et al.Experimental and clinical endocrinology & diabetes : official journal, German Society of Endocrinology [and] German Diabetes Association, 122(3), 173-178 (2014-03-20) [A relationship between analgesic and neurotropic effects by the example of milgamma].M V Zhuravleva et al.Terapevticheskii arkhiv, 84(12), 131-134 (2012-01-01) The multifaceted therapeutic potential of benfotiamineBalakumar P, et al. Pharmacological Research, 61(6), 482-488 (2010) Liver, plasma and erythrocyte levels of thiamine and its phosphate esters in rats with acute ethanol intoxication: a comparison of thiamine and benfotiamine administration.Guilherme Vannucchi Portari et al.European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences, 48(4-5), 799-802 (2013-02-02) Advanced glycation end-products inhibition improves endothelial dysfunction in rheumatoid arthritis.Ashit Syngle et al.International journal of rheumatic diseases, 15(1), 45-55 (2012-02-14) A new thiamine derivative, S-benzoylthiamine O-monophosphate.T WADA et al.Science (New York, N.Y.), 134(3473), 195-196 (1961-07-21) Biokinetic parameters and metabolism of S-benzoylthiamine-O-monophosphate.M Ziems et al.BioFactors (Oxford, England), 11(1-2), 109-110 (2000-03-08) Benfotiamine, a synthetic S-acyl thiamine derivative, has different mechanisms of action and a different pharmacological profile than lipid-soluble thiamine disulfide derivativesVolvert M L, et al. BioMed Central Pharmacology, 8(1), 10-10 (2008) The effects of long-term oral benfotiamine supplementation on peripheral nerve function and inflammatory markers in patients with type 1 diabetes: a 24-month, double-blind, randomized, placebo-controlled trial.David A Fraser et al.Diabetes care, 35(5), 1095-1097 (2012-03-27) Benfotiamine protects against peritoneal and kidney damage in peritoneal dialysis.Lars P Kihm et al.Journal of the American Society of Nephrology : JASN, 22(5), 914-926 (2011-04-23) The Effect of Benfothiamin and Vitamin D in Ischemia/Reperfusion Model of Rat Skeletal MuscleKeskin O The American Journal of Cardiology, 121(8), e4-e4 (2018) [Pathomechanism of diabetic neuropathy: background of the pathogenesis-oriented therapy].Gábor Winkler et al.Orvosi hetilap, 151(24), 971-981 (2010-06-04) Effect of benfotiamine on advanced glycation endproducts and markers of endothelial dysfunction and inflammation in diabetic nephropathy.Alaa Alkhalaf et al.PloS one, 7(7), e40427-e40427 (2012-07-14) [The importance of the pharmaceutical form and the routes of administration of B-group vitamins for the efficacious treatment of neurosensorial hearing loss].V F Antoniv et al.Vestnik otorinolaringologii, (2)(2), 57-60 (2012-07-20) Antiglycation activity of thiamin-HCl and benfotiamine in diabetic condition.Samina Kousar et al.JPMA. The Journal of the Pakistan Medical Association, 62(10), 1033-1038 (2013-07-23) Proteomic analysis of peripheral blood polymorphonuclear cells (PBMCs) reveals alteration of neutrophil extracellular trap (NET) components in uncontrolled diabetes.J Soongsathitanon et al.Molecular and cellular biochemistry, 461(1-2), 1-14 (2019-07-06) [Neuropathy pain: tactic of treatment].N K Murashko Likars'ka sprava, (6)(6), 106-113 (2013-02-05) [Sensorineural hearing loss: New prospects for therapy].A M Kornienko et al.Vestnik otorinolaringologii, (2)(2), 46-48 (2011-04-23) Boosting the pentose phosphate pathway restores cardiac progenitor cell availability in diabetes.Rajesh Katare et al.Cardiovascular research, 97(1), 55-65 (2012-09-22) Benfotiamine prevents increased β-amyloid production in HEK cells induced by high glucose.Xiao-Jing Sun et al.Neuroscience bulletin, 28(5), 561-566 (2012-09-11) [Diabetic neuropathies and angiopathies. Compensating for thiamine deficiency]. MMW Fortschritte der Medizin, 152(24), 44-45 (2010-08-03) Thiamine and benfotiamine improve cognition and ameliorate GSK-3β-associated stress-induced behaviours in mice.Nataliia Markova et al.Progress in neuro-psychopharmacology & biological psychiatry, 75, 148-156 (2016-11-09) [Prevention of complications in diabetes mellitus. Interdisciplinary collaboration to control sequelae]. MMW Fortschritte der Medizin, 153(36), 54-55 (2011-09-22) [The optimization of the treatment of the vertebrogenic pain syndrome: neurotrophic treatment potentiates the effect of nonsteroidal anti-inflammatory drugs].M G Zhestikova Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova, 112(11), 59-60 (2012-12-22) Anti-inflammatory effects of benfotiamine are mediated through the regulation of the arachidonic acid pathway in macrophages.Mohammad Shoeb et al.Free radical biology & medicine, 52(1), 182-190 (2011-11-10) Thiamine and benfotiamine prevent stress-induced suppression of hippocampal neurogenesis in mice exposed to predation without affecting brain thiamine diphosphate levels.Julie Vignisse et al.Molecular and cellular neurosciences, 82, 126-136 (2017-05-17) The detrimental effects of acute hyperglycemia on myocardial glucose uptake.Danzil Joseph et al.Life sciences, 105(1-2), 31-42 (2014-04-22) Regulation of growth, intestinal microflora composition and expression of immune-related genes by dietary supplementation of Streptococcus faecalis in blunt snout bream (Megalobrama amblycephala).Chao Xu et al.Fish & shellfish immunology, 105, 195-202 (2020-07-12)
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