熔点	-78 ºC
水溶性	不溶
沸点	158-159 ºC
闪点	29 ºC
密度	0.896
折射率	1.391-1.393

危险类别码	R10
安全说明书	S16

来源	SDS样本
没有数据	没有数据

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Bulletin of Faculty of Pharmacy, Cairo University , 54(2), 145-156 (2016) Psychiatric Side Effects of Prescription and Over-the-counter Medications: Recognition and Management (1998) Efficacy of a low-dose regimen of cyclobenzaprine hydrochloride in acute skeletal muscle spasm: results of two placebo-controlled trialsBorenstein DG and Korn S Clinical Therapeutics, 25(4), 1056-1073 (2003) Steady-state pharmacokinetics of once-daily cyclobenzaprine extended release: a randomized, double-blind, 2-period crossover study in healthy volunteers.Mona Darwish et al.Clinical therapeutics, 33(6), 746-753 (2011-06-28) Microsized graphite sensors for potentiometric determination of cyclobenzaprine hydrochloride in pure powder, tablets, and plasma.Nesrin K Ramadan et al.Journal of AOAC International, 94(6), 1807-1814 (2012-02-11) Linking pharmacology to clinical reports: cyclobenzaprine and its possible association with serotonin syndrome.J Mestres et al.Clinical pharmacology and therapeutics, 90(5), 662-665 (2011-10-07) Torticollis under cyclobenzaprine.Reinhard Reuss et al.Pharmacology, 84(2), 91-92 (2009-07-11)

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