熔点	7 ºC
密度	0.915
折射率	1.447-1.449

危险品标志	T
危险类别码	R25;R36/37/38
安全说明书	S26;S36/37/39;S45

来源	SDS样本
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Mechanisms of constitutive and ATP-evoked ATP release in neonatal mouse olfactory epithelium.Sébastien Hayoz et al.BMC neuroscience, 13, 53-53 (2012-05-30) Differential sensitivity of brainstem versus cortical astrocytes to changes in pH reveals functional regional specialization of astroglia.Vitaliy Kasymov et al.The Journal of neuroscience : the official journal of the Society for Neuroscience, 33(2), 435-441 (2013-01-11) Complete clearance of reticular erythematous mucinosis with quinacrine monotherapy.Laura Susok et al.Archives of dermatology, 148(6), 768-769 (2012-06-20) Effective endothelial cell and human pluripotent stem cell interactions generate functional insulin-producing beta cells.Dodanim Talavera-Adame et al.Diabetologia, 59(11), 2378-2386 (2016-08-29) Impedance biosensor for real-time monitoring and prediction of thrombotic individual profile in flowing blood.Denise De Zanet et al.PloS one, 12(9), e0184941-e0184941 (2017-09-19) Identification of compounds inhibiting prion replication and toxicity by removing PrPC from the cell surface.Silvia Biggi et al.Journal of neurochemistry, 152(1), 136-150 (2019-07-03) Anti-Prion Screening for Acridine, Dextran, and Tannic Acid using Real Time-Quaking Induced Conversion: A Comparison with PrPSc-Infected Cell Screening.Jae Wook Hyeon et al.PloS one, 12(1), e0170266-e0170266 (2017-01-18) Prion protein-coated magnetic beads: synthesis, characterization and development of a new ligands screening method.Marcela Cristina de Moraes et al.Journal of chromatography. 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