3-Methylsalicylic acid | CAS:83-40-9
3-Methylsalicylic acid
- 名称:3-甲基水杨酸; 3-甲基-2-羟基苯甲酸; 2-羟基-3-甲基苯甲酸; 邻甲基水杨酸 | 3-Methylsalicylic acid
- CAS号:83-40-9
- 别名:2-Hydroxy-3-methylbenzoic acid; Cresotic acid; Hydroxytoluic acid
- 分子式:C8H8O3
- 分子量:152.15
- EINESC号:201-473-8
产品描述
物理化学性质
熔点 | 164-167 ºC |
---|---|
水溶性 | 1.5 g/L (20 ºC) |
安全数据
危险品标志 | Xn |
---|---|
危险类别码 | R22;R41 |
安全说明书 | S22;S26 |
SDS
来源 | SDS样本 |
---|---|
没有数据 | 没有数据 |
产品合成路线
更多
名称 | CAS号 |
---|
更多
文章
同行评议文献
Mixed lignan-neolignans from Tarenna attenuata.Xian-Wen Yang et al.Journal of natural products, 70(4), 521-525 (2007-03-09)
The free-radical scavenger edaravone accelerates thrombolysis with alteplase in an experimental thrombosis model.Tsutomu Yamashita et al.Thrombosis research, 135(6), 1209-1213 (2015-04-25)
Synthesis, biological evaluation of prenylflavonoids as vasorelaxant and neuroprotective agents.Xiaowu Dong et al.Bioorganic & medicinal chemistry letters, 19(12), 3196-3198 (2009-05-16)
Edaravone ameliorates oxidative stress associated cholinergic dysfunction and limits apoptotic response following focal cerebral ischemia in rat.Ajmal Ahmad et al.Molecular and cellular biochemistry, 367(1-2), 215-225 (2012-06-01)
Melatonin receptor agonist ramelteon attenuates mouse acute and chronic ischemic brain injury.Xiao-Li Wu et al.Acta pharmacologica Sinica, 41(8), 1016-1024 (2020-02-29)
Influence of the labeling group on ionization and fragmentation of carbohydrates in mass spectrometry.Erika Lattová et al.Journal of the American Society for Mass Spectrometry, 16(5), 683-696 (2005-05-03)
Protective effects of MCI-186 on transplantation of bone marrow stromal cells in rat ischemic stroke model.L H Shen et al.Neuroscience, 223, 315-324 (2012-08-14)
Study on the interaction of plasma protein binding rate between edaravone and taurine in human plasma based on HPLC analysis coupled with ultrafiltration technique.Dao-quan Tang et al.Biomedical chromatography : BMC, 29(8), 1137-1145 (2014-12-30)
Separation of one-pot procedure released O-glycans as 1-phenyl-3-methyl-5-pyrazolone derivatives by hydrophilic interaction and reversed-phase liquid chromatography followed by identification using electrospray mass spectrometry and tandem mass spectrometry.Chengjian Wang et al.Journal of chromatography. A, 1274, 107-117 (2013-01-01)
Antioxidant treatment with edaravone or taurine ameliorates diabetes-induced testicular dysfunction in the rat.Panagiota Tsounapi et al.Molecular and cellular biochemistry, 369(1-2), 195-204 (2012-07-06)
Oxidative stress interferes with white matter renewal after prolonged cerebral hypoperfusion in mice.Nobukazu Miyamoto et al.Stroke, 44(12), 3516-3521 (2013-09-28)
Antioxidant treatment enhances human mesenchymal stem cell anti-stress ability and therapeutic efficacy in an acute liver failure model.Wen Zeng et al.Scientific reports, 5, 11100-11100 (2015-06-10)
Edaravone, a novel free radical scavenger, prevents steroid-induced osteonecrosis in rabbits.Guang-Yi Li et al.Rheumatology (Oxford, England), 52(3), 438-447 (2012-11-23)
Pericyte protection by edaravone after tissue plasminogen activator treatment in rat cerebral ischemia.Kentaro Deguchi et al.Journal of neuroscience research, 92(11), 1509-1519 (2014-06-19)
Beneficial effects of edaravone on the expression of serum matrix metalloproteinase-9 after cerebral hemorrhage.Fahui Zhao et al.Neurosciences (Riyadh, Saudi Arabia), 19(2), 106-110 (2014-04-18)
Separation of one-pot procedure released O-glycans as 1-phenyl-3-methyl-5-pyrazolone derivatives by hydrophilic interaction and reversed-phase liquid chromatography followed by identification using electrospray mass spectrometry and tandem mass spectrometry.Chengjian Wang et al.Journal of chromatography. A, 1274, 107-117 (2013-01-01)
Phase I clinical study of edaravone in healthy Chinese volunteers: safety and pharmacokinetics of single or multiple intravenous infusions.Hao Li et al.Drugs in R&D, 12(2), 65-70 (2012-07-06)
Capillary zone electrophoresis of reducing mono-and oligo-saccharides as the borate complexes of their 3-methyl-1-phenyl-2-pyrazolin-5-one derivativesHonda S, et al. Carbohydrate Research, 215(1), 193-198 (1991)
Protective effect of edaravone against Alzheimer's disease-relevant insults in neuroblastoma N2a cells.Yufang Yan et al.Neuroscience letters, 531(2), 160-165 (2012-11-07)
What is the role of free radical scavengers in acute stroke?Muhammad Faisal Wadiwala et al.JPMA. The Journal of the Pakistan Medical Association, 62(5), 512-513 (2012-07-05)
Neurodegenerative evidence in mice brains with cecal ligation and puncture-induced sepsis: preventive effect of the free radical scavenger edaravone.Hiroki Yokoo et al.PloS one, 7(12), e51539-e51539 (2012-12-14)
Characterization of physicochemical properties and antioxidant activity of polysaccharides from shoot residues of bamboo (Chimonobambusa quadrangularis): Effect of drying procedures.Guangjing Chen et al.Food chemistry, 292, 281-293 (2019-05-06)
Andrographolide ameliorates intracerebral hemorrhage induced secondary brain injury by inhibiting neuroinflammation induction.Xiang Li et al.Neuropharmacology, 141, 305-315 (2018-09-16)
Edaravone protects HT22 neurons from H2O2-induced apoptosis by inhibiting the MAPK signaling pathway.Zhong-Yan Zhao et al.CNS neuroscience & therapeutics, 19(3), 163-169 (2012-12-21)
Effect of a free radical scavenger on nitric oxide release in microvessels.Tsutomu Yamashita et al.Vascular pharmacology, 58(1-2), 134-139 (2012-10-31)
Protective effects of combined treatment with mild hypothermia and edaravone against cerebral ischemia/reperfusion injury via oxidative stress and Nrf2 pathway regulation.Hang Yu et al.International journal of oncology, 57(2), 500-508 (2020-07-07)
Edaravone derivatives containing NO-donor functions.Konstantin Chegaev et al.Journal of medicinal chemistry, 52(2), 574-578 (2008-12-31)
Ellipticine induces apoptosis in T-cell lymphoma via oxidative DNA damage.Cecilia Savorani et al.Leukemia & lymphoma, 56(3), 739-747 (2014-06-06)
Targeting reactive oxygen species by edaravone inhalation in a rat hyperoxic lung injury model: role of inflammasome.Chen Wang et al.Undersea & hyperbaric medicine : journal of the Undersea and Hyperbaric Medical Society, Inc, 40(6), 505-511 (2014-01-01)
Neuroprotective xanthone glycosides from Swertia punicea.Xin-Gang Du et al.Journal of natural products, 73(8), 1422-1426 (2010-08-04)
Edaravone alleviates hypoxia-acidosis/reoxygenation-induced neuronal injury by activating ERK1/2.Guibin Wang et al.Neuroscience letters, 543, 72-77 (2013-04-09)
Protective effects of edaravone combined puerarin on inhalation lung injury induced by black gunpowder smog.Zhengguan Wang et al.International immunopharmacology, 26(1), 125-132 (2015-03-11)
Attenuation of axonal injury and oxidative stress by edaravone protects against cognitive impairments after traumatic brain injury.Manabu Ohta et al.Brain research, 1490, 184-192 (2012-09-18)
Aminophylline, administered at usual doses for rodents in pharmacological studies, induces hippocampal neuronal cell injury under low tidal volume hypoxic conditions in guinea-pigs.Tomoko Somekawa-Kondo et al.The Journal of pharmacy and pharmacology, 65(1), 102-114 (2012-12-12)
Antioxidative and thrombolytic TMP nitrone for treatment of ischemic stroke.Yewei Sun et al.Bioorganic & medicinal chemistry, 16(19), 8868-8874 (2008-09-16)
Role of nitric oxide in the onset of facial nerve palsy by HSV-1 infection.Naohito Hato et al.JAMA otolaryngology-- head & neck surgery, 139(12), 1339-1342 (2013-11-10)
Reactive oxygen species and the MEK/ERK pathway are involved in the toxicity of clostridium perfringens α-toxin, a prototype bacterial phospholipase C.Laura Monturiol-Gross et al.The Journal of infectious diseases, 206(8), 1218-1226 (2012-08-21)
[Treatment of acute ischemic stroke: tissue clock and reperfusion].Shinichi Takahashi Masui. The Japanese journal of anesthesiology, 61 Suppl, S11-S22 (2013-03-22)
Pure sensory deficit at the T3 sensory level as an isolated manifestation of lateral medullary infarction.Cheng Xia et al.Neurology India, 61(3), 327-328 (2013-07-19)
Edaravone may be an efficacious adjunctive therapeutic agent for decompression sickness: an editorial perspective.Guoyang Huang et al.Undersea & hyperbaric medicine : journal of the Undersea and Hyperbaric Medical Society, Inc, 40(3), 215-217 (2013-06-26)
The free radical scavenger, edaravone, ameliorates delayed neuropsychological sequelae after acute carbon monoxide poisoning in rabbits.Wang Qingsong et al.Undersea & hyperbaric medicine : journal of the Undersea and Hyperbaric Medical Society, Inc, 40(3), 223-229 (2013-06-26)
The neuroprotective properties of the superoxide dismutase mimetic tempol correlate with its ability to reduce pathological glutamate release in a rodent model of stroke.Preeti Dohare et al.Free radical biology & medicine, 77, 168-182 (2014-09-17)
New series of antiprion compounds: pyrazolone derivatives have the potent activity of inhibiting protease-resistant prion protein accumulation.Ayako Kimata et al.Journal of medicinal chemistry, 50(21), 5053-5056 (2007-09-14)
Qualitative and Quantitative Characterization of Monosaccharide Components of Salvia miltiorrhiza, Liguspyragine Hydrochloride, and Glucose Injection.Fa-Huan Ge et al.Journal of analytical methods in chemistry, 2017, 9245620-9245620 (2017-05-11)
Edaravone increases regional cerebral blood flow after traumatic brain injury in mice.Kazuyuki Miyamoto et al.Acta neurochirurgica. Supplement, 118, 103-109 (2013-07-24)
Hydroxyl radical scavenging by edaravone derivatives: Efficient scavenging by 3-methyl-1-(pyridin-2-yl)-5-pyrazolone with an intramolecular base.Hidehiko Nakagawa et al.Bioorganic & medicinal chemistry letters, 16(23), 5939-5942 (2006-09-26)
Perfluorocarbon-facilitated CNS oxygen toxicity in rats: reversal by edaravone.Shulin Liu et al.Brain research, 1471, 56-65 (2012-07-12)
Ultrasound-promoted greener synthesis of novel trifurcate 3-substituted-chroman-2,4-dione derivatives and their drug-likeness evaluation.Chengyuan Liang et al.Molecules (Basel, Switzerland), 17(12), 14146-14158 (2012-11-30)
Edaravone protect against retinal damage in streptozotocin-induced diabetic mice.Dongqing Yuan et al.PloS one, 9(6), e99219-e99219 (2014-06-05)
Excess iodide induces an acute inhibition of the sodium/iodide symporter in thyroid male rat cells by increasing reactive oxygen species.Alejandro A Arriagada et al.Endocrinology, 156(4), 1540-1551 (2015-01-17)
Totarol prevents neuronal injury in vitro and ameliorates brain ischemic stroke: Potential roles of Akt activation and HO-1 induction.Yuanxue Gao et al.Toxicology and applied pharmacology, 289(2), 142-154 (2015-10-07)
In vivo and in vitro treatment with edaravone promotes proliferation of neural progenitor cells generated following neuronal loss in the mouse dentate gyrus.Maho Kikuta et al.Journal of pharmacological sciences, 121(1), 74-83 (2012-12-28)
Edaravone - citicoline comparative study in acute ischemic stroke (ECCS-AIS).Manish Mitta et al.The Journal of the Association of Physicians of India, 60, 36-38 (2013-06-19)
Influence of the labeling group on ionization and fragmentation of carbohydrates in mass spectrometryLattova E, et al. Journal of the American Society For Mass Spectrometry, 16(5), 683-696 (2005)
Edaravone protects cortical neurons from apoptosis by inhibiting the translocation of BAX and Increasing the interaction between 14-3-3 and p-BAD.Jin Fan et al.The International journal of neuroscience, 122(11), 665-674 (2012-07-05)
[Case of spontaneous cervical internal carotid artery dissection with embolic stroke after a job-change].Yu-Ichi Aoyama et al.Journal of UOEH, 36(4), 289-294 (2014-12-17)
Edaravone inhibits apoptosis caused by ischemia/reperfusion injury in a porcine hepatectomy model.Mitsugi Shimoda et al.World journal of gastroenterology, 18(27), 3520-3526 (2012-07-25)
Nanofiber-coated drug eluting stent for the stabilization of mast cells.Byeongtaek Oh et al.Pharmaceutical research, 31(9), 2463-2478 (2014-03-26)
备注
Products protected by valid patents are not offered for sale in countries where the sale of such products constitutes a patent infringement and its liability is at buyer's risk.
Products currently covered by valid US Patents are offered for R&D use in accordance with 35 USC 271 +A13(1).
名称 | CAS号 |
---|
相关产品
相关资讯
问
热门标签
询 单
请 填 写 相 关 信 息
- 请填写产品名称!
- CAS号
- 请正确填写公司名称!
- 请正确填写联系人!
- 请正确填写联系电话!
- 请正确填写联系邮箱!
- 请描述您的问题!