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Phenothiazine | CAS:92-84-2
Phenothiazine
  • 名称:吩噻嗪 | Phenothiazine
  • CAS号:92-84-2
  • 别名:Thiodiphenylamine; Dibenzo-p-thiazine; Dibenzo-1,4-thiazine
  • 分子式:C12H9NS
  • 分子量:199.27
  • EINESC号:202-196-5

产品描述

物理化学性质

熔点 182-187 ºC
水溶性 2 mg/L (25 ºC)
沸点 371 ºC
密度 1.362
折射率 1.6353

安全数据

危险品标志 Xi;N
危险类别码 R36/38;R43;R51/53
安全说明书 S26;S29;S36/37/39;S61

SDS

来源 SDS样本
没有数据没有数据
产品合成路线
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Exploiting protein fluctuations at the active-site gorge of human cholinesterases: further optimization of the design strategy to develop extremely potent inhibitors.Stefania Butini et al.Journal of medicinal chemistry, 51(11), 3154-3170 (2008-05-16) Japanese quail acute exposure to methamidophos: experimental design, lethal, sub-lethal effects and cholinesterase biochemical and histochemical expression.Manousos Foudoulakis et al.The Science of the total environment, 450-451, 334-347 (2012-11-14) Otoprotection in guinea pigs exposed to pesticides and ginkgo biloba.Andréa Dulor Finkler et al.Brazilian journal of otorhinolaryngology, 78(3), 122-128 (2012-06-21) Japanese quail acute exposure to methamidophos: experimental design, lethal, sub-lethal effects and cholinesterase biochemical and histochemical expression.Manousos Foudoulakis et al.The Science of the total environment, 450-451, 334-347 (2012-11-14) Effect of different oximes on rat and human cholinesterases inhibited by methamidophos: a comparative in vitro and in silico study.Thiago Henrique Lugokenski et al.Basic & clinical pharmacology & toxicology, 111(6), 362-370 (2012-06-19) Simultaneous analysis of acephate and methamidophos in human serum by improved extraction and GC-MS.Adachi N, et al. Forensic Toxicology, 26(2), 76-76 (2008) Chlorpyrifos is associated with slower serum cholinesterase recovery in acute organophosphate-poisoned patients.C H Chaou et al.Clinical toxicology (Philadelphia, Pa.), 51(5), 402-408 (2013-04-18) Mineralization of acephate, a recalcitrant organophosphate insecticide is initiated by a pseudomonad in environmental samples.Aleem Basha Pinjari et al.PloS one, 7(4), e31963-e31963 (2012-04-13) Development of a more specific and accurate multiple reaction monitoring method based on GC-EI/MS/MS for simultaneously monitoring and determining 34 kinds of pesticides in Qianjinzhidai pills.Yunbin Jiang et al.Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 983-984, 47-54 (2015-01-27) Semipreparative enantioseparation of methamidophos by HPLC-UV and preliminary in vitro study of butyrylcholinesterase inhibition.Guilherme L Emerick et al.Environmental toxicology and chemistry, 31(2), 239-245 (2011-11-03) Biochemical, histopathological and clinical evaluation of delayed effects caused by methamidophos isoforms and TOCP in hens: ameliorative effects using control of calcium homeostasis.Guilherme L Emerick et al.Toxicology, 302(1), 88-95 (2012-09-15) Association of methamidophos and sleep loss on reproductive toxicity of male mice.Lucas O Maia et al.Environmental toxicology and pharmacology, 32(2), 155-161 (2011-08-17) Avoidance behaviour of Eisenia fetida to carbofuran, chlorpyrifos, mancozeb and metamidophos in natural soils from the highlands of Colombia.Glenda García-Santos et al.Chemosphere, 84(5), 651-656 (2011-04-15) Visual detection of organophosphorus pesticides represented by mathamidophos using Au nanoparticles as colorimetric probe.Hongkun Li et al.Talanta, 87, 93-99 (2011-11-22) Enantioselective effects of methamidophos on the coelomocytes lysosomal membrane stability of Eisenia fetida.Linhua Chen et al.Bulletin of environmental contamination and toxicology, 89(6), 1161-1164 (2012-10-18) Selective solid-phase extraction using molecularly imprinted polymer for analysis of methamidophos in water and soil samples.Zhong-Lan Shen et al.Bioscience, biotechnology, and biochemistry, 75(3), 473-479 (2011-03-11) Concentration-mortality responses of Myzus persicae and natural enemies to selected insecticides.Leandro Bacci et al.Journal of environmental science and health. Part A, Toxic/hazardous substances & environmental engineering, 47(12), 1930-1937 (2012-07-05) Isatin-3-N4-benzilthiosemicarbazone, a non-toxic thiosemicarbazone derivative, protects and reactivates rat and human cholinesterases inhibited by methamidophos in vitro and in silico.Rômulo Pillon Barcelos et al.Toxicology in vitro : an international journal published in association with BIBRA, 26(6), 1030-1039 (2012-05-01) Pharmacokinetics and effects on serum cholinesterase activities of organophosphorus pesticides acephate and chlorpyrifos in chimeric mice transplanted with human hepatocytes.Hiroshi Suemizu et al.Regulatory toxicology and pharmacology : RTP, 70(2), 468-473 (2014-08-27) Influence of pesticides on the pH regulatory enzyme, carbonic anhydrase, from European Seabass liver and bovine erythrocytes.Ramazan Demirdağ et al.Environmental toxicology and pharmacology, 34(2), 218-222 (2012-05-09) IR, Raman and SERS spectral analysis and DFT calculations on the Herbicide O,S-Dimethyl phosphoramidothioate, metamidophos.Guillermo Diaz Fleming et al.Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy, 114, 120-128 (2013-06-13) [The assessment of hemoperfusion for the treatment of acute methamidophos poisoning].Deng-Pan Lai et al.Zhonghua lao dong wei sheng zhi ye bing za zhi = Zhonghua laodong weisheng zhiyebing zazhi = Chinese journal of industrial hygiene and occupational diseases, 29(6), 440-442 (2011-11-22) Acute exposure to the insecticide O,S-dimethyl phosphoramidothioate (methamidophos) leads to impairment of cardiovascular reflexes in rats.Gabriella Xavier Maretto et al.Ecotoxicology and environmental safety, 80, 203-207 (2012-04-03) Survey of resistance to four insecticides and their associated mechanisms in different genotypes of the green peach aphid (Hemiptera: Aphididae) from Chile.Eduardo Fuentes-Contreras et al.Journal of economic entomology, 106(1), 400-407 (2013-03-02) Biological monitoring for exposure to methamidophos: a human oral dosing study.F Garner et al.Toxicology letters, 231(2), 277-281 (2014-10-15) SulE, a sulfonylurea herbicide de-esterification esterase from Hansschlegelia zhihuaiae S113.Bao-Jian Hang et al.Applied and environmental microbiology, 78(6), 1962-1968 (2012-01-17) Assessment of long-term and recent pesticide exposure among rural school children in Nicaragua.Teresa Rodríguez et al.Occupational and environmental medicine, 69(2), 119-125 (2011-07-05) Evaluation of male-mediated reproductive toxic effects of methamidophos in the mouse.A T Farag et al.Andrologia, 44(2), 116-124 (2011-04-14) Detections of eleven organophosphorus insecticides and one herbicide threatening Pacific salmonids, Oncorhynchus spp., in California, 1991-2010.Emily B Lisker et al.Bulletin of environmental contamination and toxicology, 87(4), 355-360 (2011-06-29) Comparative in vitro study of the inhibition of human and hen esterases by methamidophos enantiomers.Guilherme L Emerick et al.Toxicology, 292(2-3), 145-150 (2011-12-27) [Survey of pesticide residues in imported frozen vegetables and fruits (1989.4~2008.3)].Maki Kobayashi et al.Shokuhin eiseigaku zasshi. Journal of the Food Hygienic Society of Japan, 52(2), 121-129 (2011-04-26) Exposure to methamidophos at adulthood adversely affects serotonergic biomarkers in the mouse brain.Carla S Lima et al.Neurotoxicology, 32(6), 718-724 (2011-08-30)
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