5-Norbornene-2-methylamine | CAS:95-10-3
5-Norbornene-2-methylamine
- 名称:降冰片烯-2-甲胺; 1-双环[2.2.1]庚-5-烯-2-基甲胺 | 5-Norbornene-2-methylamine
- CAS号:95-10-3
- 别名:1-Bicyclo[2.2.1]hept-5-en-2-ylmethanamine
- 分子式:C8H13N
- 分子量:123.20
- EINESC号:
产品描述
物理化学性质
没有数据 | 没有数据 |
---|
安全数据
没有数据 | 没有数据 |
---|
SDS
来源 | SDS样本 |
---|---|
没有数据 | 没有数据 |
产品合成路线
更多
名称 | CAS号 |
---|
更多
文章
同行评议文献
Simple and sensitive screening and quantitative determination of 88 psychoactive drugs and their metabolites in blood through LC-MS/MS: application on postmortem samples.Cristina Sempio et al.Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 970, 1-7 (2014-09-15)
Structure-Based Screen Identifies a Potent Small Molecule Inhibitor of Stat5a/b with Therapeutic Potential for Prostate Cancer and Chronic Myeloid Leukemia.Zhiyong Liao et al.Molecular cancer therapeutics, 14(8), 1777-1793 (2015-05-31)
A selective USP1-UAF1 inhibitor links deubiquitination to DNA damage responses.Qin Liang et al.Nature chemical biology, 10(4), 298-304 (2014-02-18)
Multiple sclerosis-associated IL2RA polymorphism controls GM-CSF production in human TH cells.Felix J Hartmann et al.Nature communications, 5, 5056-5056 (2014-10-04)
Effect of GnRHa, pimozide and Ovaprim on ovulation and plasma sex steroid hormones in African catfish Clarias gariepinus.S M Sharaf Theriogenology, 77(8), 1709-1716 (2012-03-01)
Delusions of parasitosis: ethical and clinical considerations.Stephanie Fabbro et al.Journal of the American Academy of Dermatology, 69(1), 156-159 (2013-06-19)
The STAT5 inhibitor pimozide decreases survival of chronic myelogenous leukemia cells resistant to kinase inhibitors.Erik A Nelson et al.Blood, 117(12), 3421-3429 (2011-01-15)
The role of pimozide in clinical psychiatry: a review.L A Opler et al.The Journal of clinical psychiatry, 52(5), 221-233 (1991-05-01)
Assessment of STAT5 as a potential therapy target in enzalutamide-resistant prostate cancer.Holger H H Erb et al.PloS one, 15(8), e0237248-e0237248 (2020-08-14)
Metabolic effects of aripiprazole and pimozide in children with Tourette syndrome.Renata Rizzo et al.Pediatric neurology, 47(6), 419-422 (2012-11-07)
Pimozide: a review of its pharmacological properties and therapeutic uses in psychiatry.R M Pinder et al.Drugs, 12(1), 1-40 (1976-01-01)
Depletion of STAT5 blocks TEL-SYK-induced APMF-type leukemia with myelofibrosis and myelodysplasia in mice.C Sprissler et al.Blood cancer journal, 4, e240-e240 (2014-08-26)
Non-antiepileptic drugs for trigeminal neuralgia.Mi Yang et al.The Cochrane database of systematic reviews, (1)(1), CD004029-CD004029 (2011-01-21)
Progesterone downregulation of miR-141 contributes to expansion of stem-like breast cancer cells through maintenance of progesterone receptor and Stat5a.J Finlay-Schultz et al.Oncogene, 34(28), 3676-3687 (2014-09-23)
A human ether-á-go-go-related (hERG) ion channel atomistic model generated by long supercomputer molecular dynamics simulations and its use in predicting drug cardiotoxicity.Anwar Anwar-Mohamed et al.Toxicology letters, 230(3), 382-392 (2014-08-17)
USP1 (ubiquitin specific peptidase 1) targets ULK1 and regulates its cellular compartmentalization and autophagy.Marzia Raimondi et al.Autophagy, 15(4), 613-630 (2018-10-20)
Cardiovascular safety of aripiprazole and pimozide in young patients with Tourette syndrome.Mariangela Gulisano et al.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology, 32(6), 1213-1217 (2011-07-07)
Pimozide treatment of tic and Tourette disorders.A K Shapiro et al.Pediatrics, 79(6), 1032-1039 (1987-06-01)
Distributed Plasticity Drives Visual Habituation Learning in Larval Zebrafish.Owen Randlett et al.Current biology : CB, 29(8), 1337-1345 (2019-04-09)
Efficacy of Helicobacter pylori eradication for the 1st line treatment of immune thrombocytopenia patients with moderate thrombocytopenia.Hawk Kim et al.Annals of hematology, 94(5), 739-746 (2014-12-17)
Identification of thioridazine, an antipsychotic drug, as an antiglioblastoma and anticancer stem cell agent using public gene expression data.H-W Cheng et al.Cell death & disease, 6, e1753-e1753 (2015-05-08)
Effects of in vivo treatment with the dopamine antagonist pimozide and gonadotropin-releasing hormone agonist (GnRHa) on the reproductive axis of Senegalese sole (Solea senegalensis).José M Guzmán et al.Comparative biochemistry and physiology. Part A, Molecular & integrative physiology, 158(2), 235-245 (2010-11-30)
A pharmacologically validated, high-capacity, functional thallium flux assay for the human Ether-à-go-go related gene potassium channel.William A Schmalhofer et al.Assay and drug development technologies, 8(6), 714-726 (2010-12-17)
Activity Profile of an FDA-Approved Compound Library against Schistosoma mansoni.Gordana Panic et al.PLoS neglected tropical diseases, 9(7), e0003962-e0003962 (2015-08-01)
Clinical uses of pimozide.M J Tueth et al.Southern medical journal, 86(3), 344-349 (1993-03-01)
Automated high-content live animal drug screening using C. elegans expressing the aggregation prone serpin α1-antitrypsin Z.Sager J Gosai et al.PloS one, 5(11), e15460-e15460 (2010-11-26)
Management of status dystonicus in children. Cases report and review.Salvatore Grosso et al.European journal of paediatric neurology : EJPN : official journal of the European Paediatric Neurology Society, 16(4), 390-395 (2012-01-17)
The efficacy of anticonvulsants on orofacial pain: a systematic review.Wilhelmus J J M Martin et al.Oral surgery, oral medicine, oral pathology, oral radiology, and endodontics, 111(5), 627-633 (2011-04-19)
Pimozide for schizophrenia or related psychoses.J Rathbone et al.The Cochrane database of systematic reviews, (3)(3), CD001949-CD001949 (2007-07-20)
The efficacy of anticonvulsants on orofacial pain: a systematic review.Wilhelmus J J M Martin et al.Oral surgery, oral medicine, oral pathology, oral radiology, and endodontics, 111(5), 627-633 (2011-04-19)
Screening of DUB activity and specificity by MALDI-TOF mass spectrometry.Maria Stella Ritorto et al.Nature communications, 5, 4763-4763 (2014-08-28)
Pimozide augmentation of clozapine inpatients with schizophrenia and schizoaffective disorder unresponsive to clozapine monotherapy.Joseph I Friedman et al.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 36(6), 1289-1295 (2011-02-25)
Selective and cell-active inhibitors of the USP1/ UAF1 deubiquitinase complex reverse cisplatin resistance in non-small cell lung cancer cells.Junjun Chen et al.Chemistry & biology, 18(11), 1390-1400 (2011-11-29)
Aripiprazole as a viable alternative for treating delusions of parasitosis.Barry Ladizinski et al.Journal of drugs in dermatology : JDD, 9(12), 1531-1532 (2010-12-02)
Pimozide: use in Tourette's syndrome.C L Colvin et al.Drug intelligence & clinical pharmacy, 19(6), 421-424 (1985-06-01)
Sustained inhibition of STAT5, but not JAK2, is essential for TKI-induced cell death in chronic myeloid leukemia.L Schafranek et al.Leukemia, 29(1), 76-85 (2014-05-13)
Efficacy of pimozide augmentation for clozapine partial responders with schizophrenia.Handan Gunduz-Bruce et al.Schizophrenia research, 143(2-3), 344-347 (2012-12-12)
FLT3-ITD confers resistance to the PI3K/Akt pathway inhibitors by protecting the mTOR/4EBP1/Mcl-1 pathway through STAT5 activation in acute myeloid leukemia.Ayako Nogami et al.Oncotarget, 6(11), 9189-9205 (2015-04-01)
Pimozide in dermatologic practice: a comprehensive review.Cynthia R Lorenzo et al.American journal of clinical dermatology, 5(5), 339-349 (2004-11-24)
Two structurally different T-type Ca 2+ channel inhibitors, mibefradil and pimozide, protect CA1 neurons from delayed death after global ischemia in rats.M Bancila et al.Fundamental & clinical pharmacology, 25(4), 469-478 (2010-11-03)
CYP2D6 genotype information to guide pimozide treatment in adult and pediatric patients: basis for the U.S. Food and Drug Administration's new dosing recommendations.Hobart L Rogers et al.The Journal of clinical psychiatry, 73(9), 1187-1190 (2012-10-13)
Pimozide for schizophrenia or related psychoses.Meghana Mothi et al.The Cochrane database of systematic reviews, 11(11), CD001949-CD001949 (2013-11-07)
The effect of nutrition on the neural mechanisms potentially involved in melatonin-stimulated LH secretion in female Mediterranean goats.Luis A Zarazaga et al.The Journal of endocrinology, 211(3), 263-272 (2011-09-10)
Adrenal fasciculata cells express T-type and rapidly and slowly activating L-type Ca2+ channels that regulate cortisol secretion.John J Enyeart et al.American journal of physiology. Cell physiology, 308(11), C899-C918 (2015-03-20)
Pimozide for schizophrenia or related psychoses.A Sultana et al.The Cochrane database of systematic reviews, (2)(2), CD001949-CD001949 (2000-05-05)
Pharmacological treatment of tic disorders and Tourette Syndrome.Veit Roessner et al.Neuropharmacology, 68, 143-149 (2012-06-26)
The novel adenosine A2A antagonist Lu AA47070 reverses the motor and motivational effects produced by dopamine D2 receptor blockade.Lyndsey E Collins et al.Pharmacology, biochemistry, and behavior, 100(3), 498-505 (2011-11-01)
Signal transducer and activator of transcription 5a inhibited by pimozide may regulate survival of goat mammary gland epithelial cells by regulating parathyroid hormone-related protein.Hui Li et al.Gene, 551(2), 279-289 (2014-09-10)
Pimozide: use in dermatology.Willem A van Vloten Dermatology online journal, 9(2), 3-3 (2003-03-18)
Phosphorylated STAT3 (Tyr705) as a biomarker of response to pimozide treatment in triple-negative breast cancer.Sundee Dees et al.Cancer biology & therapy, 21(6), 506-521 (2020-03-14)
Integrating constitutive gene expression and chemoactivity: mining the NCI60 anticancer screen.David G Covell PloS one, 7(10), e44631-e44631 (2012-10-12)
Pimozide for tics in Tourette's syndrome.Tamara Pringsheim et al.The Cochrane database of systematic reviews, (2)(2), CD006996-CD006996 (2009-04-17)
Dual inhibition of Jak2 and STAT5 enhances killing of myeloproliferative neoplasia cells.M Bar-Natan et al.Leukemia, 26(6), 1407-1410 (2011-12-03)
Induction and activation of human Th17 by targeting antigens to dendritic cells via dectin-1.Dorothée Duluc et al.Journal of immunology (Baltimore, Md. : 1950), 192(12), 5776-5788 (2014-05-20)
Factors influencing crystal growth rates from undercooled liquids of pharmaceutical compounds.Niraj S Trasi et al.The journal of physical chemistry. B, 118(33), 9974-9982 (2014-07-31)
Intraspinal administration of interleukin-7 promotes neuronal apoptosis and limits functional recovery through JAK/STAT5 pathway following spinal cord injury.Xiaochen Yuan et al.Biochemical and biophysical research communications, 514(3), 1023-1029 (2019-05-10)
Pimozide for schizophrenia or related psychoses.A Sultana et al.The Cochrane database of systematic reviews, (3)(3), CD001949-CD001949 (2000-07-25)
Successful treatment of Morgellons disease with pimozide therapy.Erika Elise Reid et al.Archives of dermatology, 146(10), 1191-1193 (2010-10-20)
Changes in the product label for pimozide illustrate both the promises and the challenges of personalized medicine.Sheldon H Preskorn The Journal of clinical psychiatry, 73(9), 1191-1193 (2012-10-13)
Serotonin 5-HT7 receptors mediate relaxation of porcine pial veins.Ishine, T. American Journal of Physiology. Heart and Circulatory Physiology, 278 (2000)
IL-3 synergises with basophil-derived IL-4 and IL-13 to promote the alternative activation of human monocytes.Francesco Borriello et al.European journal of immunology, 45(7), 2042-2051 (2015-04-01)
Pimozide.Robert Smyj et al.Profiles of drug substances, excipients, and related methodology, 37, 287-311 (2012-04-04)
备注
Products protected by valid patents are not offered for sale in countries where the sale of such products constitutes a patent infringement and its liability is at buyer's risk.
Products currently covered by valid US Patents are offered for R&D use in accordance with 35 USC 271 +A13(1).
名称 | CAS号 |
---|
相关产品
相关资讯
问
热门标签
询 单
请 填 写 相 关 信 息
- 请填写产品名称!
- CAS号
- 请正确填写公司名称!
- 请正确填写联系人!
- 请正确填写联系电话!
- 请正确填写联系邮箱!
- 请描述您的问题!