熔点	43-45 ºC
水溶性	起反应
沸点	276 ºC
闪点	180 ºC

危险品标志	C
危险类别码	R34
安全说明书	S24/25;S7/8

来源	SDS样本
没有数据	没有数据

产品合成路线

更多

名称	CAS号

更多

文章

同行评议文献

Dexamethasone and rosiglitazone are sufficient and necessary for producing functional adipocytes from mesenchymal stem cells.David Contador et al.Experimental biology and medicine (Maywood, N.J.), 240(9), 1235-1246 (2015-01-18) GW9662, a potent antagonist of PPARgamma, inhibits growth of breast tumour cells and promotes the anticancer effects of the PPARgamma agonist rosiglitazone, independently of PPARgamma activationSeargent JM, et al. British Journal of Pharmacology, 143(8), 933-937 (2004) c-Flip KO fibroblasts display lipid accumulation associated with endoplasmic reticulum stress.Claudia Giampietri et al.Biochimica et biophysica acta, 1851(7), 929-936 (2015-03-10) Conjugated linoleic acid induces an atheroprotective macrophage MΦ2 phenotype and limits foam cell formation.Monica de Gaetano et al.Journal of inflammation (London, England), 12, 15-15 (2015-02-28) Peroxisome proliferator activated receptor gamma is not necessary for the development of LPS-induced tolerance in macrophages.Basilia Zingarelli et al.Immunology, 124(1), 51-57 (2007-11-22) Expression of 15-Hydroxyprostaglandin Dehydrogenase in Human Chorion Is Associated with Peroxisome Proliferator-Activated Receptor Isoform Expression in Term Labor.Ping He et al.The American journal of pathology, 185(7), 1981-1990 (2015-06-22) Immunometabolic modulation of retinal inflammation by CD36 ligand.Katia Mellal et al.Scientific reports, 9(1), 12903-12903 (2019-09-11) Adipose PD-L1 Modulates PD-1/PD-L1 Checkpoint Blockade Immunotherapy Efficacy in Breast Cancer.Bogang Wu et al.Oncoimmunology, 7(11), e1500107-e1500107 (2018-11-06) HIF-1A and C/EBPs transcriptionally regulate adipogenic differentiation of bone marrow-derived MSCs in hypoxia.Chen Jiang et al.Stem cell research & therapy, 6, 21-21 (2015-04-19) Lipopolysaccharide Downregulates 11β-Hydroxysteroid Dehydrogenase 2 Expression through Inhibiting Peroxisome Proliferator-Activated Receptor-γ in Placental Trophoblasts.Lin Fu et al.Journal of immunology (Baltimore, Md. : 1950), 203(5), 1198-1207 (2019-07-19) Curcumin protects neurons against oxygen-glucose deprivation/reoxygenation-induced injury through activation of peroxisome proliferator-activated receptor-γ function.Zun-Jing Liu et al.Journal of neuroscience research, 92(11), 1549-1559 (2014-07-01) Suppression of multidrug resistance by rosiglitazone treatment in human ovarian cancer cells through downregulation of FZD1 and MDR1 genes.Hui Zhang et al.Anti-cancer drugs, 26(7), 706-715 (2015-06-09) Rosiglitzone suppresses angiotensin II-induced production of KLF5 and cell proliferation in rat vascular smooth muscle cells.Dengfeng Gao et al.PloS one, 10(4), e0123724-e0123724 (2015-04-16) Duration and magnitude of extracellular signal-regulated protein kinase phosphorylation determine adipogenesis or osteogenesis in human bone marrow-derived stem cells.Ho Sun Jung et al.Yonsei medical journal, 52(1), 165-172 (2010-12-15) Novel Mechanism of Cholesterol Transport by ABCA5 in Macrophages and Its Role in Dyslipidemia.Aleepta Guha Ray et al.Journal of molecular biology, 432(17), 4922-4941 (2020-07-21) LECT2, a Ligand for Tie1, Plays a Crucial Role in Liver Fibrogenesis.Meng Xu et al.Cell, 178(6), 1478-1492 (2019-09-03) The PPAR-gamma antagonist GW9662 elicits differentiation of M2c-like cells and upregulation of the MerTK/Gas6 axis: a key role for PPAR-gamma in human macrophage polarizationZizzo G and Cohen PL Journal of Inflammation, 12(1), 36-36 (2015) Sesamin suppresses macrophage-derived chemokine expression in human monocytes via epigenetic regulation.Chong-Chao Hsieh et al.Food & function, 5(10), 2494-2500 (2014-08-15) Combination Treatment with PPARgamma Ligand and Its Specific Inhibitor GW9662 Downregulates BIS and 14-3-3 Gamma, Inhibiting Stem-Like Properties in Glioblastoma CellsIm CN BioMed Research International, 2017(1), 36-36 (2017) Angiotensin-(1-7) stimulates cholesterol efflux from angiotensin II-treated cholesterol-loaded THP-1 macrophages through the suppression of p38 and c-Jun N-terminal kinase signaling.Hui-Yu Yang et al.Molecular medicine reports, 12(1), 1387-1392 (2015-03-18) Voluntary exercise protects against ulcerative colitis by up-regulating glucocorticoid-mediated PPAR-γ activity in the colon in mice.W-X Liu et al.Acta physiologica (Oxford, England), 215(1), 24-36 (2015-06-03) p38 MAPK-inhibited dendritic cells induce superior antitumour immune responses and overcome regulatory T-cell-mediated immunosuppression.Yong Lu et al.Nature communications, 5, 4229-4229 (2014-06-25) Activation of PPAR gamma receptors reduces levodopa-induced dyskinesias in 6-OHDA-lesioned rats.A A Martinez et al.Neurobiology of disease, 74, 295-304 (2014-12-09) Proapoptotic PEDF functional peptides inhibit prostate tumor growth--a mechanistic study.Qing Gong et al.Biochemical pharmacology, 92(3), 425-437 (2014-09-28) Arsenic trioxide inhibits liver cancer stem cells and metastasis by targeting SRF/MCM7 complex.Hai-Yang Wang et al.Cell death & disease, 10(6), 453-453 (2019-06-13) The synergistic enhancement of cloning efficiency in individualized human pluripotent stem cells by peroxisome proliferative-activated receptor-gamma (PPARgamma) activation and rho-associated kinase (ROCK) inhibitionKajabadi NS, et al. The Journal of Biological Chemistry, 290(43), 26303-26313 (2015) Hepatic circadian-clock system altered by insulin resistance, diabetes and insulin sensitizer in mice.Huey-Ling Tseng et al.PloS one, 10(3), e0120380-e0120380 (2015-03-24) Aquaporin 7 involved in GINSENOSIDE-RB1-mediated anti-obesity via peroxisome proliferator-activated receptor gamma pathway.Rong Guo et al.Nutrition & metabolism, 17, 69-69 (2020-08-22) TLR4-mediated inflammation promotes foam cell formation of vascular smooth muscle cell by upregulating ACAT1 expression.Y W Yin et al.Cell death & disease, 5, e1574-e1574 (2014-12-19) Curcumin retunes cholesterol transport homeostasis and inflammation response in M1 macrophage to prevent atherosclerosis.Fang-Yuan Chen et al.Biochemical and biophysical research communications, 467(4), 872-878 (2015-10-17) Autonomous inhibition of apoptosis correlates with responsiveness of colon carcinoma cell lines to ciglitazone.David M Baron et al.PloS one, 9(12), e114158-e114158 (2014-12-17) The synergistic enhancement of cloning efficiency in individualized human pluripotent stem cells by peroxisome proliferative-activated receptor-gamma (PPARgamma) activation and rho-associated kinase (ROCK) inhibitionKajabadi NS, et al. The Journal of Biological Chemistry, 290(43), 26303-26313 (2015) Exercise Alleviates Obesity-Induced Metabolic Dysfunction via Enhancing FGF21 Sensitivity in Adipose Tissues.Leiluo Geng et al.Cell reports, 26(10), 2738-2752 (2019-03-07) The effect of pioglitazone on aldosterone and cortisol production in HAC15 human adrenocortical carcinoma cells.Zhi-qiang Pan et al.Molecular and cellular endocrinology, 394(1-2), 119-128 (2014-07-20) Bezafibrate attenuates pressure overload-induced cardiac hypertrophy and fibrosisXu SC, et al. PPAR Research, 2017(43), 26303-26313 (2017) Celecoxib suppresses hepatoma stemness and progression by up-regulating PTEN.Tian-Huei Chu et al.Oncotarget, 5(6), 1475-1490 (2014-04-12) Additive Renoprotection by Pioglitazone and Fenofibrate against Inflammatory, Oxidative and Apoptotic Manifestations of Cisplatin Nephrotoxicity: Modulation by PPARs.Mai M Helmy et al.PloS one, 10(11), e0142303-e0142303 (2015-11-05) Oxidized low-density lipoprotein suppresses expression of prostaglandin E receptor subtype EP3 in human THP-1 macrophages.Xuxia Sui et al.PloS one, 9(10), e110828-e110828 (2014-10-22) Telmisartan attenuated LPS-induced neuroinflammation in human IMR-32 neuronal cell line via SARM in AT1R independent mechanism.Prathab Balaji Saravanan et al.Life sciences, 130, 88-96 (2015-03-31) Manganese superoxide dismutase deficiency triggers mitochondrial uncoupling and the Warburg effect.Y Xu et al.Oncogene, 34(32), 4229-4237 (2014-11-05) Molecules involve in the self-protection of neurons against glucose-oxygen-serum deprivation (GOSD)-induced cell damage.Chen-Hsuan Wang et al.Brain research bulletin, 79(3-4), 169-176 (2009-05-12) Antinociceptive and antidiarrheal effects of pioglitazone in a rat model of diarrhoea-predominant irritable bowel syndrome: role of nitric oxide.Pedram Paragomi et al.Clinical and experimental pharmacology & physiology, 41(2), 118-126 (2014-01-30) Inhibition of peroxisome proliferator-activated receptor gamma prevents the melanogenesis in murine B16/F10 melanoma cells.Jiun-Han Chen et al.BioMed research international, 2014, 695797-695797 (2014-09-25) Krüppel-like factor 4 modulates the migration and invasion of hepatoma cells by suppressing TIMP-1 and TIMP-2.Ming-Ta Sung et al.Oncology reports, 34(1), 439-446 (2015-05-09) Mechanisms of Nifedipine-Downregulated CD40L/sCD40L Signaling in Collagen Stimulated Human Platelets.Tso-Hsiao Chen et al.PloS one, 10(5), e0127054-e0127054 (2015-05-15) Regulation of neural crest cell fate by the retinoic acid and Pparg signalling pathways.Nan Li et al.Development (Cambridge, England), 137(3), 389-394 (2010-01-19) The peroxisome proliferator activated receptor gamma agonist pioglitazone increases functional expression of the glutamate transporter excitatory amino acid transporter 2 (EAAT2) in human glioblastoma cells.Jared Ching et al.Oncotarget, 6(25), 21301-21314 (2015-06-06) Lysophosphatidic acid enhances survival of human CD34(+) cells in ischemic conditions.Ivana Kostic et al.Scientific reports, 5, 16406-16406 (2015-11-11) Functional consequences of cysteine modification in the ligand binding sites of peroxisome proliferator activated receptors by GW9662Leesnitzer LM, et al. Biochemistry, 41(21), 6640-6650 (2002) Mechanistic investigation of PPARγ-facilitated anti-asthmatic effects of Galangin (Norizalpinin): Insights from in silico and in vivo analyses.Linda Jeeva Kumari Henry et al.Biochemical and biophysical research communications, 526(3), 833-840 (2020-04-11) CD36-mediated uptake of myelin debris by macrophages and microglia reduces neuroinflammation.Elien Grajchen et al.Journal of neuroinflammation, 17(1), 224-224 (2020-07-29) Rosiglitazone suppresses HIV-1 Tat-induced vascular inflammation via Akt signaling.Wen Huang et al.Molecular and cellular biochemistry, 407(1-2), 173-179 (2015-06-07) Cooperative therapeutic action of retinoic acid receptor and retinoid x receptor agonists in a mouse model of Alzheimer's disease.Kohichi Kawahara et al.Journal of Alzheimer's disease : JAD, 42(2), 587-605 (2014-06-12) Cardiomyocyte-specific expression of CYP2J2 prevents development of cardiac remodelling induced by angiotensin II.Zuowen He et al.Cardiovascular research, 105(3), 304-317 (2015-01-27) Estrogen modulation properties of mangiferin and quercetin and the mangiferin metabolite norathyriol.Ashley S Wilkinson et al.Food & function, 6(6), 1847-1854 (2015-05-06) Mevastatin ameliorates sphingosine 1-phosphate-induced COX-2/PGE2-dependent cell migration via FoxO1 and CREB phosphorylation and translocation.Chih-Kai Hsu et al.British journal of pharmacology, 172(22), 5360-5376 (2015-09-12) Cardioprotective Effects of Atorvastatin Are Mediated Through PPARγ in Paraquat-Exposed Rats.Mojtaba Malekinejad et al.Journal of cardiovascular pharmacology, 74(5), 400-408 (2019-08-20) Telmisartan activates endothelial nitric oxide synthase via Ser1177 phosphorylation in vascular endothelial cells.Masahiro Myojo et al.PloS one, 9(5), e96948-e96948 (2014-05-16) CINPA1 is an inhibitor of constitutive androstane receptor that does not activate pregnane X receptor.Milu T Cherian et al.Molecular pharmacology, 87(5), 878-889 (2015-03-13) FMR1 Reactivating Treatments in Fragile X iPSC-Derived Neural Progenitors In Vitro and In Vivo.Dan Vershkov et al.Cell reports, 26(10), 2531-2539 (2019-03-07) Novel thiazolidinedione mitoNEET ligand-1 acutely improves cardiac stem cell survival under oxidative stress.Suzanna J Logan et al.Basic research in cardiology, 110(2), 19-19 (2015-03-03) Rosiglitazone attenuates insulin-like growth factor 1 receptor survival signaling in PC-3 cells.Efstathia Papageorgiou et al.Molecular medicine (Cambridge, Mass.), 14(7-8), 403-411 (2008-05-14) Protective effect of telmisartan against oxidative damage induced by high glucose in neuronal PC12 cell.Habib Eslami et al.Neuroscience letters, 558, 31-36 (2013-11-12) Inhibition of COX-2-mediated eicosanoid production plays a major role in the anti-inflammatory effects of the endocannabinoid N-docosahexaenoylethanolamine (DHEA) in macrophages.Jocelijn Meijerink et al.British journal of pharmacology, 172(1), 24-37 (2014-05-02)

备注