熔点	-99 ºC
水溶性	3 g/100 mL (20 ºC)
沸点	111-112 ºC
闪点	16 ºC
密度	0.87
折射率	1.388-1.39

危险品标志	F
危险类别码	R11;R66
安全说明书	S16;S23;S25;S29;S33

来源	SDS样本
没有数据	没有数据

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[Research on the preparative method of Arctigenin].Li-Ying Zhang et al.Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials, 35(3), 467-470 (2012-08-11) Herba epimedii flavonoids suppress osteoclastic differentiation and bone resorption by inducing G2/M arrest and apoptosis.Dawei Zhang et al.Biochimie, 94(12), 2514-2522 (2012-07-17) [Progress of pharmacological research on icariin].Li Li et al.Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, 33(23), 2727-2732 (2009-03-06) Inhibition of Th1/Th17 responses via suppression of STAT1 and STAT3 activation contributes to the amelioration of murine experimental colitis by a natural flavonoid glucoside icariin.Feifei Tao et al.Biochemical pharmacology, 85(6), 798-807 (2012-12-25) The beneficial effect of Icariin on bone is diminished in osteoprotegerin-deficient mice.Dong Zheng et al.Bone, 51(1), 85-92 (2012-05-04) A systematic review of the efficacy and pharmacological profile of Herba Epimedii in osteoporosis therapy.Yuan-Kun Zhai et al.Die Pharmazie, 68(9), 713-722 (2013-10-24) Icariin promotes histone acetylation and attenuates post-stroke cognitive impairment in the central cholinergic circuits of mice.X Wang et al.Neuroscience, 236, 281-288 (2013-02-02) Metabolite profiles of icariin in rat plasma by ultra-fast liquid chromatography coupled to triple-quadrupole/time-of-flight mass spectrometry.Qian Qian et al.Journal of pharmaceutical and biomedical analysis, 66, 392-398 (2012-04-24) Icariin attenuates hypoxia-induced oxidative stress and apoptosis in osteoblasts and preserves their osteogenic differentiation potential in vitro.H-P Ma et al.Cell proliferation, 47(6), 527-539 (2014-10-31) mGluR5 stimulating Homer-PIKE formation initiates icariin induced cardiomyogenesis of mouse embryonic stem cells by activating reactive oxygen species.Limin Zhou et al.Experimental cell research, 319(10), 1505-1514 (2013-03-26) Enhancement of epimedium fried with suet oil based on in vivo formation of self-assembled flavonoid compound nanomicelles.Li Cui et al.Molecules (Basel, Switzerland), 17(11), 12984-12996 (2012-11-03) [Icariin and its pharmaceutical efficacy: research progress of molecular mechanism].Yang Chen et al.Zhong xi yi jie he xue bao = Journal of Chinese integrative medicine, 9(11), 1179-1184 (2011-11-18) Icariin improves cognitive deficits and activates quiescent neural stem cells in aging rats.Bin Wu et al.Journal of ethnopharmacology, 142(3), 746-753 (2012-06-13) Inhibitory effect of icariin on Ti-induced inflammatory osteoclastogenesis.Jingfu Cui et al.The Journal of surgical research, 192(2), 447-453 (2014-06-28) Icariin: a potential promoting compound for cartilage tissue engineering.D Li et al.Osteoarthritis and cartilage, 20(12), 1647-1656 (2012-08-25) [Effect of icariin on learning and memory abilities and activity of cholinergic system of senescence-accelerated mice SAMP10].Linna Gao et al.Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, 37(14), 2117-2121 (2012-11-07) Icariin Attenuates Amyloid-β (Aβ)-Induced Neuronal Insulin Resistance Through PTEN Downregulation.Xiaomei Zou et al.Frontiers in pharmacology, 11, 880-880 (2020-06-26) High-performance liquid chromatography-based multivariate analysis to predict the estrogenic activity of an Epimedium koreanum extract.M Nurul Islam et al.Bioscience, biotechnology, and biochemistry, 76(5), 923-927 (2012-06-29) [Effects of icariin and genistein on peak bone mass in rats].Kui Cheng et al.Zhongguo yi xue ke xue yuan xue bao. Acta Academiae Medicinae Sinicae, 35(5), 542-546 (2013-11-05) Impaired hypothalamic insulin signaling in CUMS rats: restored by icariin and fluoxetine through inhibiting CRF system.Ying Pan et al.Psychoneuroendocrinology, 38(1), 122-134 (2012-06-06) Icariin inhibits corticosterone-induced apoptosis in hypothalamic neurons via the PI3-K/Akt signaling pathway.Hongying Zhang et al.Molecular medicine reports, 6(5), 967-972 (2012-08-28) Icariin Ameliorates Palmitate-Induced Insulin Resistance Through Reducing Thioredoxin-Interacting Protein (TXNIP) and Suppressing ER Stress in C2C12 Myotubes.Mingxin Li et al.Frontiers in pharmacology, 9, 1180-1180 (2018-11-22) [Variation of icariin and total flavonoid of Epimedium acuminatum in different parts and habitats].Tao Zhou et al.Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, 37(13), 1917-1921 (2012-10-02) Icariin delays homocysteine-induced endothelial cellular senescence involving activation of the PI3K/AKT-eNOS signaling pathway.Duan Xiao-Hong et al.Pharmaceutical biology, 51(4), 433-440 (2013-01-23) Icariin: does it have an osteoinductive potential for bone tissue engineering?Xin Zhang et al.Phytotherapy research : PTR, 28(4), 498-509 (2013-07-05) Icariin promotes bone formation via the BMP-2/Smad4 signal transduction pathway in the hFOB 1.19 human osteoblastic cell line.Wenna Liang et al.International journal of molecular medicine, 30(4), 889-895 (2012-07-31) Functions and action mechanisms of flavonoids genistein and icariin in regulating bone remodeling.Lei-Guo Ming et al.Journal of cellular physiology, 228(3), 513-521 (2012-07-11) Changes in the intestinal absorption mechanism of icariin in the nanocavities of cyclodextrins.Ye Zhang et al.International journal of nanomedicine, 7, 4239-4249 (2012-08-21) Variation of medicinal components in a unique geographical accession of horny goat weed Epimedium sagittatum Maxim. (Berberidaceae).Qiong Liang et al.Molecules (Basel, Switzerland), 17(11), 13345-13356 (2012-11-10) Immunoadjuvant activity of icariin that induces Th1-type antibody in mice.Ki Yon Rhew et al.Archives of pharmacal research, 35(9), 1685-1691 (2012-10-12) [Comparative study on chemical quality of main species of epimedium].Sun Han et al.Yao xue xue bao = Acta pharmaceutica Sinica, 47(4), 502-507 (2012-07-17) Icariin from Epimedium brevicornum Maxim promotes the biosynthesis of estrogen by aromatase (CYP19).Lijuan Yang et al.Journal of ethnopharmacology, 145(3), 715-721 (2012-12-25) Icariin protects against titanium particle-induced osteolysis and inflammatory response in a mouse calvarial model.Hongguo Shao et al.Biomaterials, 60, 92-99 (2015-05-20) [Icariin reduces mitochondrial oxidative stress injury in diabetic rat hearts].Huilan Bao et al.Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, 36(11), 1503-1507 (2012-07-12) Icariin associated with exercise therapy is an effective treatment for postmenopausal osteoporosis.Meng Liu et al.Chinese medical journal, 125(10), 1784-1789 (2012-07-18)

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