询 单
请 填 写 相 关 信 息
产品信息
产品名称
别名
CAS号
结构式 上传
联系方式
公司
联系人
电话
邮箱
内容
提交
中文版 English
请输入产品名称、CAS式、分子式
6-Hydroxycortisol | CAS:3078-34-0
6-Hydroxycortisol
  • 名称:6-羟基皮质醇 | 6-Hydroxycortisol
  • CAS号:3078-34-0
  • 别名:(11beta)-6,11,17,21-Tetrahydroxypregn-4-ene-3,20-dione
  • 分子式:C21H30O6
  • 分子量:378.46
  • EINESC号:

产品描述

物理化学性质

密度 1.35±0.1 g/cm3 (20 ºC

安全数据

没有数据没有数据

SDS

来源 SDS样本
没有数据没有数据
产品合成路线
更多

名称 CAS号
更多
文章
同行评议文献
A derivative of L-allo threonine alleviates 2,4-dinitrofluorobenzene-induced atopic dermatitis indications.Jin-Chul Heo et al.Bioscience, biotechnology, and biochemistry, 76(11), 2021-2025 (2012-11-08) Effects of Ixeris dentata water extract and caffeic acid on allergic inflammation in vivo and in vitro.Yong-Deok Jeon et al.BMC complementary and alternative medicine, 15, 196-196 (2015-06-25) Rutin suppresses atopic dermatitis and allergic contact dermatitis.Jin Kyeong Choi et al.Experimental biology and medicine (Maywood, N.J.), 238(4), 410-417 (2013-06-14) Histone deacetylases inhibitor Trichostatin A ameliorates DNFB-induced allergic contact dermatitis and reduces epidermal Langerhans cells in mice.Yu-Ling Shi et al.Journal of dermatological science, 68(2), 99-107 (2012-09-25) Vascular endothelial growth factor c/vascular endothelial growth factor receptor 3 signaling regulates chemokine gradients and lymphocyte migration from tissues to lymphatics.Daiki Iwami et al.Transplantation, 99(4), 668-677 (2015-01-22) β-arrestin 2 inhibits proinflammatory chemokine production and attenuates contact allergic inflammation in the skin.Evelyn Gaffal et al.The Journal of investigative dermatology, 134(8), 2131-2137 (2014-03-01) P-selectin-mediated monocyte-cerebral endothelium adhesive interactions link peripheral organ inflammation to sickness behaviors.Charlotte D'Mello et al.The Journal of neuroscience : the official journal of the Society for Neuroscience, 33(37), 14878-14888 (2013-09-13) Distinct photorespiratory reactions are preferentially catalyzed by glutamate:glyoxylate and serine:glyoxylate aminotransferases in rice.Zhisheng Zhang et al.Journal of photochemistry and photobiology. B, Biology, 142, 110-117 (2014-12-22) Differential expression of cell surface markers in response to 2,4-dinitrofluorobenzene in RAW 264.7 and primary immune cells.Dongbum Kim et al.BMB reports, 45(9), 538-543 (2012-09-27) Tetrahydrocannabinol Reduces Hapten-Driven Mast Cell Accumulation and Persistent Tactile Sensitivity in Mouse Model of Allergen-Provoked Localized Vulvodynia.Beebie Boo et al.International journal of molecular sciences, 20(9) (2019-05-06) Functional peptide nanocarriers for delivery of novel anti-RelA RNA interference agents as a topical treatment of atopic dermatitis.Takanori Kanazawa et al.International journal of pharmaceutics, 489(1-2), 261-267 (2015-05-10) MicroRNA 150 in humans and murine contact sensitivity.Joel Wolf et al.Journal of drugs in dermatology : JDD, 11(10), 1152-1152 (2013-01-05) Tryptanthrin ameliorates atopic dermatitis through down-regulation of TSLP.Na-Ra Han et al.Archives of biochemistry and biophysics, 542, 14-20 (2013-12-04) IL-1β-dependent activation of dendritic epidermal T cells in contact hypersensitivity.Morten M Nielsen et al.Journal of immunology (Baltimore, Md. : 1950), 192(7), 2975-2983 (2014-03-07) A20-deficient mast cells exacerbate inflammatory responses in vivo.Klaus Heger et al.PLoS biology, 12(1), e1001762-e1001762 (2014-01-24) Cigarette smoke exposure inhibits contact hypersensitivity via the generation of platelet-activating factor agonists.Ravi P Sahu et al.Journal of immunology (Baltimore, Md. : 1950), 190(5), 2447-2454 (2013-01-29) Microbial Genetics (2014) Glutamine suppresses DNFB-induced contact dermatitis by deactivating p38 mitogen-activated protein kinase via induction of MAPK phosphatase-1.Otgonzaya Ayush et al.The Journal of investigative dermatology, 133(3), 723-731 (2012-10-19) Self-assembled polymeric nanoparticles for percutaneous co-delivery of hydrocortisone/hydroxytyrosol: an ex vivo and in vivo study using an NC/Nga mouse model.Zahid Hussain et al.International journal of pharmaceutics, 444(1-2), 109-119 (2013-01-23) Cutting edge: CD69 interference with sphingosine-1-phosphate receptor function regulates peripheral T cell retention.Laura K Mackay et al.Journal of immunology (Baltimore, Md. : 1950), 194(5), 2059-2063 (2015-01-28) Effects of intestinal bacteria-derived p-cresyl sulfate on Th1-type immune response in vivo and in vitro.Takahiro Shiba et al.Toxicology and applied pharmacology, 274(2), 191-199 (2013-10-29) Linoleoyl ethanolamide reduces lipopolysaccharide-induced inflammation in macrophages and ameliorates 2,4-dinitrofluorobenzene-induced contact dermatitis in mice.Tsukasa Ishida et al.European journal of pharmacology, 699(1-3), 6-13 (2012-12-04) Modifications of mesenteric adipose tissue during moderate experimental colitis in mice.Isabelle Olivier et al.Life sciences, 94(1), 1-7 (2013-11-13) A natural dye, Niram improves atopic dermatitis through down-regulation of TSLP.Na-Ra Han et al.Environmental toxicology and pharmacology, 38(3), 982-990 (2014-12-03) Lymphatic Function Regulates Contact Hypersensitivity Dermatitis in Obesity.Ira L Savetsky et al.The Journal of investigative dermatology, 135(11), 2742-2752 (2015-07-16) Imaging protective mast cells in living mice during severe contact hypersensitivityReber LL, et al. JCI insight, 2(9), e92900-e92900 (2017) Immune response against 2,4-dinitrofluorobenzene-induced atopic dermatitis-like clinical manifestation is suppressed by spermidine in NC/Nga mice.G-D Kim et al.Scandinavian journal of immunology, 81(4), 221-228 (2015-02-04) Spinal IL-33/ST2 signaling mediates chronic itch in mice through the astrocytic JAK2-STAT3 cascade.Lixia Du et al.Glia, 67(9), 1680-1693 (2019-05-16) Depletion of regulatory T cells in a hapten-induced inflammation model results in prolonged and increased inflammation driven by T cells.A D Christensen et al.Clinical and experimental immunology, 179(3), 485-499 (2014-10-11) Downregulation of immunological mediators in 2,4-dinitrofluorobenzene-induced atopic dermatitis-like skin lesions by hydrocortisone-loaded chitosan nanoparticles.Zahid Hussain et al.International journal of nanomedicine, 9, 5143-5156 (2014-11-15) Development and Use a Novel combined in-vivo and in-vitro Assay for Anti-inflammatory and Immunosuppressive Agents.Tan Li et al.Iranian journal of pharmaceutical research : IJPR, 12(3), 445-455 (2013-11-20) Antagonistic effect of the inflammasome on thymic stromal lymphopoietin expression in the skin.Sonia Schuepbach-Mallepell et al.The Journal of allergy and clinical immunology, 132(6), 1348-1357 (2013-08-21) Hydrogel-gauze dressing for moderate-to-severe atopic dermatitis: development and efficacy study on atopic dermatitis-like skin lesions in NC/Nga mice.Shiow-Fern Ng et al.Drug development and industrial pharmacy, 40(11), 1538-1546 (2013-09-13) Cross-linking protein glutathionylation mediated by O2-arylated bis-diazeniumdiolate "Double JS-K".Ryan J Holland et al.Chemical research in toxicology, 25(12), 2670-2677 (2012-10-31) Immunopontentiating and antitumor activities of a polysaccharide from Pulsatilla chinensis (Bunge) Regel.Tong Liu et al.International journal of biological macromolecules, 54, 225-229 (2012-12-19) Double domain swapping in bovine seminal RNase: formation of distinct N- and C-swapped tetramers and multimers with increasing biological activities.Giovanni Gotte et al.PloS one, 7(10), e46804-e46804 (2012-10-17) Phenolic composition and effects on allergic contact dermatitis of phenolic extracts Sapium sebiferum (L.) Roxb. leaves.Rao Fu et al.Journal of ethnopharmacology, 162, 176-180 (2015-01-13) Topical tacrolimus treatment does not facilitate photocarcinogenesis in cancer-prone mice.Takeo Shiga et al.Journal of dermatological science, 68(2), 112-115 (2012-09-18) Bamboo salt suppresses skin inflammation in mice with 2, 4-dinitrofluorobenzene-induced atopic dermatitisYoou MS, et al. Chinese Journal of Natural Medicines, 16(2), 97-104 (2018) Glutathione metabolism in the HaCaT cell line as a model for the detoxification of the model sensitisers 2,4-dinitrohalobenzenes in human skin.Sandrine Jacquoilleot et al.Toxicology letters, 237(1), 11-20 (2015-05-30) Sphingolipids as new biomarkers for assessment of delayed-type hypersensitivity and response to triptolide.Feng Qu et al.PloS one, 7(12), e52454-e52454 (2013-01-10) Topical Lyogel Containing Corticosteroid Decreases IgE Expression and Enhances the Therapeutic Efficacy Against Atopic Eczema.Shiow-Fern Ng et al.AAPS PharmSciTech, 16(3), 656-663 (2014-12-17) DOCK8 regulates lymphocyte shape integrity for skin antiviral immunity.Qian Zhang et al.The Journal of experimental medicine, 211(13), 2549-2566 (2014-11-26) Tac1-Expressing Neurons in the Periaqueductal Gray Facilitate the Itch-Scratching Cycle via Descending RegulationGao ZR, et al. Neuron, 101(9), 45-59 (2018) Skin sensitization induced Langerhans' cell mobilization: variable requirements for tumour necrosis factor-α.Laura H Eaton et al.Immunology, 144(1), 139-148 (2014-07-22) CCR10 regulates balanced maintenance and function of resident regulatory and effector T cells to promote immune homeostasis in the skin.Mingcan Xia et al.The Journal of allergy and clinical immunology, 134(3), 634-644 (2014-04-29) Effects of astaxanthin on dinitrofluorobenzene-induced contact dermatitis in mice.Hyungwoo Kim et al.Molecular medicine reports, 12(3), 3632-3638 (2015-06-06) Silymarin inhibits ultraviolet radiation-induced immune suppression through DNA repair-dependent activation of dendritic cells and stimulation of effector T cells.Mudit Vaid et al.Biochemical pharmacology, 85(8), 1066-1076 (2013-02-12) Successful development of methodology for detection of hapten-specific contact hypersensitivity (CHS) memory in swine.E J Putz et al.PloS one, 14(10), e0223483-e0223483 (2019-10-10) 1,5-Disubstituted benzimidazoles that direct cardiomyocyte differentiation from mouse embryonic stem cells.Karl J Okolotowicz et al.Bioorganic & medicinal chemistry, 23(17), 5282-5292 (2015-08-19) Therapeutic potential of B and T lymphocyte attenuator expressed on CD8+ T cells for contact hypersensitivity.Daiki Nakagomi et al.The Journal of investigative dermatology, 133(3), 702-711 (2012-11-30) Improvement of derivatized amino acid detection sensitivity in micellar electrokinetic capillary chromatography by means of acid-induced pH-mediated stacking technique.Szymon Dziomba et al.Analytical and bioanalytical chemistry, 406(26), 6713-6721 (2014-08-26) NKG2D-dependent activation of dendritic epidermal T cells in contact hypersensitivity.Morten M Nielsen et al.The Journal of investigative dermatology, 135(5), 1311-1319 (2015-01-31) Effects of baicalin cream in two mouse models: 2,4-dinitrofluorobenzene-induced contact hypersensitivity and mouse tail test for psoriasis.Jie Wu et al.International journal of clinical and experimental medicine, 8(2), 2128-2137 (2015-05-02) Inducible deletion of the Blimp-1 gene in adult epidermis causes granulocyte-dominated chronic skin inflammation in mice.Ming-Feng Chiang et al.Proceedings of the National Academy of Sciences of the United States of America, 110(16), 6476-6481 (2013-04-12) CCR8 regulates contact hypersensitivity by restricting cutaneous dendritic cell migration to the draining lymph nodes.Rikio Yabe et al.International immunology, 27(4), 169-181 (2014-10-27) Synergistic action of dendritic mitochondria and creatine kinase maintains ATP homeostasis and actin dynamics in growing neuronal dendrites.Kansai Fukumitsu et al.The Journal of neuroscience : the official journal of the Society for Neuroscience, 35(14), 5707-5723 (2015-04-10) Binding of WIP to actin is essential for T cell actin cytoskeleton integrity and tissue homing.Michel J Massaad et al.Molecular and cellular biology, 34(23), 4343-4354 (2014-09-24) Cannabinoid 1 receptors in keratinocytes modulate proinflammatory chemokine secretion and attenuate contact allergic inflammation.Evelyn Gaffal et al.Journal of immunology (Baltimore, Md. : 1950), 190(10), 4929-4936 (2013-04-16) Lack of transglutaminase 2 diminished T-cell responses in mice.Jin-Hee Kim et al.Immunology, 142(3), 506-516 (2014-03-19) The inhibitory effect of naringenin on atopic dermatitis induced by DNFB in NC/Nga mice.Tae-Ho Kim et al.Life sciences, 93(15), 516-524 (2013-08-13) CCR7 Chemokine Receptor-Inducible lnc-Dpf3 Restrains Dendritic Cell Migration by Inhibiting HIF-1α-Mediated Glycolysis.Juan Liu et al.Immunity, 50(3), 600-615 (2019-03-03) Rivastigmine alleviates experimentally induced colitis in mice and rats by acting at central and peripheral sites to modulate immune responses.Helena Shifrin et al.PloS one, 8(2), e57668-e57668 (2013-03-08) Prospective phospholipid markers for skin sensitization prediction in keratinocytes: a phospholipidomic approach.Deolinda R Santinha et al.Archives of biochemistry and biophysics, 533(1-2), 33-41 (2013-03-12) CXCR3 deficiency prolongs Th1-type contact hypersensitivity.Hiraku Suga et al.Journal of immunology (Baltimore, Md. : 1950), 190(12), 6059-6070 (2013-05-10) Local Mast Cell Activation Promotes Neovascularization.Ilze Bot et al.Cells, 9(3) (2020-03-18) Amorphous silicon dioxide nanoparticles modulate immune responses in a model of allergic contact dermatitis.Brian C Palmer et al.Scientific reports, 9(1), 5085-5085 (2019-03-27) Natural killer T cells are essential for the development of contact hypersensitivity in BALB/c mice.Chihiro Shimizuhira et al.The Journal of investigative dermatology, 134(11), 2709-2718 (2014-04-24) Physicochemical changes in phosphorylase kinase induced by its cationic activator Mg(2+).Weiya Liu et al.Protein science : a publication of the Protein Society, 22(4), 444-454 (2013-01-30) Local and systemic effects of co-stimulatory blockade using cytotoxic T lymphocyte antigen-4-immunoglobulin in dinitrofluorobenzene- and oxazolone-induced contact hypersensitivity in mice.A D Christensen et al.Clinical and experimental immunology, 171(2), 220-230 (2013-01-05) Complementary methods for contact hypersensitivity (CHS) evaluation in mice.Magdalena Zemelka-Wiącek et al.Journal of immunological methods, 387(1-2), 270-275 (2012-11-28) [Study on the immunocompetence of polysaccharide extracted from root of Salvia miltiorrhiza].Xiang-Dong Zhang et al.Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials, 35(6), 949-952 (2012-12-15)
备注

Products protected by valid patents are not offered for sale in countries where the sale of such products constitutes a patent infringement and its liability is at buyer's risk.

Products currently covered by valid US Patents are offered for R&D use in accordance with 35 USC 271 +A13(1).

名称 CAS号

相关产品

相关资讯

热门标签
询 单
请 填 写 相 关 信 息
产品信息
产品名称
别名
CAS号
结构式 上传
联系方式
公司
联系人
电话
邮箱
内容
提交