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1-Chlorobutane | CAS:109-69-3
1-Chlorobutane
  • 名称:1-氯丁烷; 氯代正丁烷; 正丁基氯 | 1-Chlorobutane
  • CAS号:109-69-3
  • 别名:n-Butyl chloride
  • 分子式:C4H9Cl
  • 分子量:92.57
  • EINESC号:203-696-6

产品描述

物理化学性质

熔点 -123 ºC
水溶性 0.5 g/L (20 ºC)
沸点 77-78 ºC
闪点 -12 ºC
密度 0.886
折射率 1.4014-1.4034

安全数据

危险品标志 F
危险类别码 R11
安全说明书 S16;S29;S9

SDS

来源 SDS样本
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Potential benefits of supplementation with auraptene in cystic fibrosis.Amirhossein Sahebkar Clinical nutrition (Edinburgh, Scotland), 30(2), 259-260 (2010-09-25) Anti-inflammatory and neuroprotective effects of auraptene, a citrus coumarin, following cerebral global ischemia in mice.Satoshi Okuyama et al.European journal of pharmacology, 699(1-3), 118-123 (2012-12-12) Auraptene-induced cytotoxicity mechanisms in human malignant glioblastoma (U87) cells: role of reactive oxygen species (ROS).Amir R Afshari et al.EXCLI journal, 18, 576-590 (2019-10-16) Auraptene and its effects on the re-emergence of colon cancer stem cells.Francesco Epifano et al.Phytotherapy research : PTR, 27(5), 784-786 (2012-07-05) Variation in Key Flavonoid Biosynthetic Enzymes and Phytochemicals in 'Rio Red' Grapefruit (Citrus paradisi Macf.) during Fruit Development.Priyanka R Chaudhary et al.Journal of agricultural and food chemistry, 64(47), 9022-9032 (2016-11-04) A natural propenoic acid derivative activates peroxisome proliferator-activated receptor-beta/delta (PPARbeta/delta).Salvatore Genovese et al.Life sciences, 86(13-14), 493-498 (2010-02-16) Citrus compounds inhibit inflammation- and obesity-related colon carcinogenesis in mice.Takuji Tanaka et al.Nutrition and cancer, 60 Suppl 1, 70-80 (2008-11-15) Behavioral and molecular effects of intrahippocampal infusion of auraptene, resveratrol, and curcumin on H-89-induced deficits on spatial memory acquisition and retention in Morris water maze.K Tabrizian et al.Human & experimental toxicology, 38(7), 775-784 (2019-04-05) Novel prodrugs for the treatment of colonic diseases based on 5-aminosalicylic acid, 4'-geranyloxyferulic acid, and auraptene: biological activities and analytical assays.Francesco Epifano et al.Current drug delivery, 9(2), 112-121 (2012-01-31) Suppression of mitochondrial respiration with auraptene inhibits the progression of renal cell carcinoma: involvement of HIF-1α degradation.Yunseon Jang et al.Oncotarget, 6(35), 38127-38138 (2015-10-17) Semisynthetic studies identify mitochondria poisons from botanical dietary supplements--geranyloxycoumarins from Aegle marmelos.Jun Li et al.Bioorganic & medicinal chemistry, 21(7), 1795-1803 (2013-02-26) A new approach to examining the extraction process of Zhishi and Zhiqiao considering the synergistic effect of complex mixtures by PAMPA.Hui Li et al.Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 1099, 10-17 (2018-09-22) Citrus auraptene: a potential multifunctional therapeutic agent for nonalcoholic fatty liver disease.Amirhossein Sahebkar Annals of hepatology, 10(4), 575-577 (2011-09-14) Integrated and global pseudotargeted metabolomics strategy applied to screening for quality control markers of Citrus TCMs.Yisong Shu et al.Analytical and bioanalytical chemistry, 409(20), 4849-4865 (2017-07-12) Citrus nobiletin suppresses bone loss in ovariectomized ddY mice and collagen-induced arthritis in DBA/1J mice: possible involvement of receptor activator of NF-kappaB ligand (RANKL)-induced osteoclastogenesis regulation.Akira Murakami et al.BioFactors (Oxford, England), 30(3), 179-192 (2008-06-06) Regulation of Human Platelet Activation and Prevention of Arterial Thrombosis in Mice by Auraptene through Inhibition of NF-κB Pathway.Chih-Wei Hsia et al.International journal of molecular sciences, 21(13) (2020-07-11) Auraptene from Ferula szowitsiana protects human peripheral lymphocytes against oxidative stress.Fatemeh Soltani et al.Phytotherapy research : PTR, 24(1), 85-89 (2009-05-16) Effects of selected food phytochemicals in reducing the toxic actions of TCDD and p,p'-DDT in U937 macrophages.Eric M Sciullo et al.Archives of toxicology, 84(12), 957-966 (2010-09-25) Suppression of CD74 expression and Helicobacter pylori adhesion by auraptene targeting serum starvation-activated ERK1/2 in NCI-N87 gastric carcinoma cells.Hirotaka Sekiguchi et al.Bioscience, biotechnology, and biochemistry, 74(5), 1018-1024 (2010-05-13) Characterization of three small molecule inhibitors of enterovirus 71 identified from screening of a library of natural products.Guiming Li et al.Antiviral research, 143, 85-96 (2017-04-17) Chemoprevention with phytochemicals targeting inducible nitric oxide synthase.Akira Murakami Forum of nutrition, 61, 193-203 (2009-04-16) Preparation and quantification of the total phenolic products in Citrus fruit using solid-phase extraction coupled with high-performance liquid chromatography with diode array and UV detection.Honglian Zeng et al.Journal of separation science, 39(19), 3806-3817 (2016-08-06) Auraptene induces apoptosis via myeloid cell leukemia 1-mediated activation of caspases in PC3 and DU145 prostate cancer cellsLee J C, et al. Phytotherapy Research, 31(6), 891-898 (2017) Auraptene: a natural biologically active compound with multiple targets.Salvatore Genovese et al.Current drug targets, 12(3), 381-386 (2010-10-20) Auraptene and Its Role in Chronic Diseases Drug Discovery from Mother Nature, 399-407 (2016) Auraptene Mitigates Parkinson's Disease-Like Behavior by Protecting Inhibition of Mitochondrial Respiration and Scavenging Reactive Oxygen Species.Yunseon Jang et al.International journal of molecular sciences, 20(14) (2019-07-25) The plant coumarins auraptene and lacinartin as potential multifunctional therapeutic agents for treating periodontal disease.Annie Marquis et al.BMC complementary and alternative medicine, 12, 80-80 (2012-06-30) Methyl galbanate, a novel inhibitor of nitric oxide production in mouse macrophage RAW264.7 cells.Susumu Kohno et al.Journal of natural medicines, 65(2), 353-359 (2011-01-20) Development of a quantitative bioassay to assess preventive compounds against inflammation-based carcinogenesis.Kunishige Onuma et al.Nitric oxide : biology and chemistry, 25(2), 183-194 (2011-02-25) Synergy between Auraptene, Ionizing Radiation, and Anticancer Drugs in Colon Adenocarcinoma Cells.Mahdi Moussavi et al.Phytotherapy research : PTR, 31(9), 1369-1375 (2017-07-05) Auraptene attenuates gastritis via reduction of Helicobacter pylori colonization and pro-inflammatory mediator production in C57BL/6 mice.Hirotaka Sekiguchi et al.Journal of medicinal food, 15(7), 658-663 (2012-04-05) Effects of ATRA combined with citrus and ginger-derived compounds in human SCC xenografts.Heather E Kleiner-Hancock et al.BMC cancer, 10, 394-394 (2010-07-28) Auraptene regulates gene expression involved in lipid metabolism through PPARα activation in diabetic obese mice.Nobuyuki Takahashi et al.Molecular nutrition & food research, 55(12), 1791-1797 (2011-11-01) Aggressive mammary carcinoma progression in Nrf2 knockout mice treated with 7,12-dimethylbenz[a]anthracene.Lisa Becks et al.BMC cancer, 10, 540-540 (2010-10-12) Systematic Detection and Identification of Bioactive Ingredients from Citrus aurantium L. var. amara Using HPLC-Q-TOF-MS Combined with a Screening Method.Liuyi Yu et al.Molecules (Basel, Switzerland), 25(2) (2020-01-19) Identification, synthesis and quantification of process-related impurities in auraptene.Yan-Gang Li et al.Journal of pharmaceutical and biomedical analysis, 56(2), 191-199 (2011-06-28)
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Products currently covered by valid US Patents are offered for R&D use in accordance with 35 USC 271 +A13(1).

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