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Fumaric acid | CAS:110-17-8
Fumaric acid
  • 名称:富马酸; 反丁烯二酸 | Fumaric acid
  • CAS号:110-17-8
  • 别名:(E)-2-Butenedioic acid; Butenedioic acid; (E)-1,2-Ethenedicarboxylic acid; TMEDA
  • 分子式:C4H4O4
  • 分子量:116.07
  • EINESC号:203-743-0

产品描述

物理化学性质

熔点 295-300 ºC
水溶性 0.63 g/100 mL (25 ºC)
闪点 230 ºC
密度 1.625

安全数据

危险品标志 Xi
危险类别码 R36
安全说明书 S26

SDS

来源 SDS样本
没有数据没有数据
产品合成路线
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The amino acid residue at position 95 and the third CDR region in the H chain determine the ceiling affinity and the maturation pathway of an anti-(4-hydroxy-3-nitrophenyl)acetyl antibody.Akikazu Murakami et al.Molecular immunology, 48(1-3), 48-58 (2010-10-22) IgM-mediated signaling is required for the development of a normal B cell memory response.Linjie Guo et al.Molecular immunology, 45(4), 1071-1077 (2007-09-11) Escherichia coli NsrR regulates a pathway for the oxidation of 3-nitrotyramine to 4-hydroxy-3-nitrophenylacetate.Linda D Rankin et al.Journal of bacteriology, 190(18), 6170-6177 (2008-07-29) Enhancing effect of 4-hydroxy-3-nitrophenylacetic acid on transcription of the ice nucleation-active gene of Xanthomonas campestris.M Watanabe et al.Bioscience, biotechnology, and biochemistry, 58(12), 2269-2270 (1994-12-01) IL-21 receptor is critical for the development of memory B cell responses.Andrew L Rankin et al.Journal of immunology (Baltimore, Md. : 1950), 186(2), 667-674 (2010-12-21) Defining the immunological phenotype of Fc receptor-like B (FCRLB) deficient mice: Confounding role of the inhibitory FcγRIIb.Keiji Masuda et al.Cellular immunology, 266(1), 24-31 (2010-09-28) Recirculating CD4 memory T cells mount rapid secondary responses without major contributions from follicular CD4 effectors and B cells.Sanjiv A Luther et al.European journal of immunology, 37(6), 1476-1484 (2007-05-17) Nitric oxide regulates BAFF expression and T cell-independent antibody responses.Daniela Giordano et al.Journal of immunology (Baltimore, Md. : 1950), 193(3), 1110-1120 (2014-06-22) Early B blasts acquire a capacity for Ig class switch recombination that is lost as they become plasmablasts.Jennifer L Marshall et al.European journal of immunology, 41(12), 3506-3512 (2011-09-21) Augmented antibody response with premature germinal center regression in CD40L transgenic mice.Yusuke Kishi et al.Journal of immunology (Baltimore, Md. : 1950), 185(1), 211-219 (2010-05-28) Structural elucidation of the mechanistic basis of degeneracy in the primary humoral response.Tarique Khan et al.Journal of immunology (Baltimore, Md. : 1950), 188(4), 1819-1827 (2012-01-24) PLC-gamma2 is essential for formation and maintenance of memory B cells.Masaki Hikida et al.The Journal of experimental medicine, 206(3), 681-689 (2009-03-11) B cells in T follicular helper cell development and function: separable roles in delivery of ICOS ligand and antigen.Jason S Weinstein et al.Journal of immunology (Baltimore, Md. : 1950), 192(7), 3166-3179 (2014-03-13) Urinary excretion of the nitrotyrosine metabolite 3-nitro-4-hydroxyphenylacetic acid in preterm and term infants.Thomas Hoehn et al.Neonatology, 93(2), 73-76 (2007-08-09) Quinoline-3-carboxamides modulate primary T cell-dependent B cell responses but do not inhibit functional immunity.E Källberg et al.Scandinavian journal of immunology, 79(4), 237-243 (2014-01-05) Correction of age-associated deficiency in germinal center response by immunization with immune complexes.Biao Zheng et al.Clinical immunology (Orlando, Fla.), 124(2), 131-137 (2007-06-15) Antigen-induced B cell apoptosis is independent of complement C4.K B Faust et al.Clinical and experimental immunology, 150(1), 132-139 (2007-07-25) A role for DRAK2 in the germinal center reaction and the antibody response.Ahmed Al-Qahtani et al.Autoimmunity, 41(5), 341-352 (2008-06-24) Characterization of memory B cells responsible for affinity maturation of anti- (4-hydroxy-3-nitrophenyl)acetyl (NP) antibodies.Miyuki Nishimura et al.International immunology, 23(4), 271-285 (2011-03-23) The affinity maturation of anti-4-hydroxy-3-nitrophenylacetyl mouse monoclonal antibody. A calorimetric study of the antigen-antibody interaction.H Torigoe et al.The Journal of biological chemistry, 270(38), 22218-22222 (1995-09-22) B cell antigen extraction is regulated by physical properties of antigen-presenting cells.Katelyn M Spillane et al.The Journal of cell biology, 216(1), 217-230 (2016-12-08) H2-O, a MHC class II-like protein, sets a threshold for B-cell entry into germinal centers.Nicole A Draghi et al.Proceedings of the National Academy of Sciences of the United States of America, 107(38), 16607-16612 (2010-09-03) Intraclonal competition inhibits the formation of high-affinity antibody-secreting cells.Thuc-vy L Le et al.Journal of immunology (Baltimore, Md. : 1950), 181(9), 6027-6037 (2008-10-23) Preferential localization of IgG memory B cells adjacent to contracted germinal centers.Yuichi Aiba et al.Proceedings of the National Academy of Sciences of the United States of America, 107(27), 12192-12197 (2010-06-16) Innate retroviral restriction by Apobec3 promotes antibody affinity maturation in vivo.Mario L Santiago et al.Journal of immunology (Baltimore, Md. : 1950), 185(2), 1114-1123 (2010-06-23) Re-utilization of germinal centers in multiple Peyer's patches results in highly synchronized, oligoclonal, and affinity-matured gut IgA responses.P Bergqvist et al.Mucosal immunology, 6(1), 122-135 (2012-07-13) ICOS, CD40, and lymphotoxin beta receptors signal sequentially and interdependently to initiate a germinal center reaction.Frances Vu et al.Journal of immunology (Baltimore, Md. : 1950), 180(4), 2284-2293 (2008-02-06) A role for lysosomal-associated protein transmembrane 5 in the negative regulation of surface B cell receptor levels and B cell activation.Rika Ouchida et al.Journal of immunology (Baltimore, Md. : 1950), 185(1), 294-301 (2010-06-04) The pericyte and stromal cell marker CD248 (endosialin) is required for efficient lymph node expansion.Siân Lax et al.European journal of immunology, 40(7), 1884-1889 (2010-05-01) CD4 T Follicular Helper Cells Prevent Depletion of Follicular B Cells in Response to Cecal Ligation and Puncture.Matthew D Taylor et al.Frontiers in immunology, 11, 1946-1946 (2020-09-10) Effects of antibody affinity and antigen valence on molecular forms of immune complexes.Masayuki Oda et al.Molecular immunology, 47(2-3), 357-364 (2009-10-06) Thymus-independent class switch recombination is affected by APRIL.Gijs Hardenberg et al.Immunology and cell biology, 86(6), 530-534 (2008-03-26)
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