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1-Acetyl-2-phenylhydrazine | CAS:114-83-0
1-Acetyl-2-phenylhydrazine
  • 名称:1-乙酰基-2-苯基肼; N-乙酰苯肼 | 1-Acetyl-2-phenylhydrazine
  • CAS号:114-83-0
  • 别名:2-Phenylacetohydrazide
  • 分子式:C8H10N2O
  • 分子量:150.18
  • EINESC号:204-055-3

产品描述

物理化学性质

熔点 128-132 ºC

安全数据

危险品标志 Xn
危险类别码 R22;R36/37/38;R43
安全说明书 S22;S26;S36

SDS

来源 SDS样本
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Investigation on the mechanisms of genotoxicity of butadiene, styrene and their combination in human lymphocytes using the Comet assay.Eduardo Cemeli et al.Mutation research, 664(1-2), 69-76 (2009-05-12) Point mutations induced by 1,2-epoxy-3-butene N1 deoxyinosine adducts.D A Rodriguez et al.Environmental and molecular mutagenesis, 38(4), 292-296 (2002-01-05) Reaction kinetic studies for comparison of mutagenic potency between butadiene monoxide and glycidamide.Hitesh V Motwani et al.Chemico-biological interactions, 288, 57-64 (2018-04-14) In vivo doses of butadiene epoxides as estimated from in vitro enzyme kinetics by using cob(I)alamin and measured hemoglobin adducts: an inter-species extrapolation approach.Hitesh V Motwani et al.Toxicology and applied pharmacology, 281(3), 276-284 (2014-12-03) Mutational spectrum of 1,3-butadiene and metabolites 1,2-epoxybutene and 1,2,3,4-diepoxybutane to assess mutagenic mechanisms.L Recio et al.Chemico-biological interactions, 135-136, 325-341 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adduct, originating from 1,2-epoxy-3,4-butanediol, is the major DNA adduct after exposure to [2,3-(14)C]-1,3-butadiene,[4-(14)C]-1,2-epoxy-3-butane.P J Boogaard et al.Chemico-biological interactions, 135-136, 687-693 (2001-06-09) Some insights into the mode of action of butadiene by examining the genotoxicity of its metabolites.A D Kligerman et al.Chemico-biological interactions, 166(1-3), 132-139 (2006-05-16) In vitro genotoxicity testing of (1-chloroethenyl)oxirane, a metabolite of beta-chloroprene.M W Himmelstein et al.Chemico-biological interactions, 135-136, 703-713 (2001-06-09) Structure of an oligodeoxynucleotide containing a butadiene oxide-derived N1 beta-hydroxyalkyl deoxyinosine adduct in the human N-ras codon 61 sequence.Tandace A Scholdberg et al.Biochemistry, 44(9), 3327-3337 (2005-03-02) Stereospecific uncatalyzed alpha-O-glycosylation and alpha-C-glycosidation by means of a new D-Gulal-derived alpha vinyl oxirane.Valeria Di Bussolo et al.The Journal of organic chemistry, 69(21), 7383-7386 (2004-10-09) 3,4-Epoxy-1-butene, a reactive metabolite of 1,3-butadiene, induces somatic mutations in Xpc-null mice.J K Wickliffe et al.Environmental and molecular mutagenesis, 47(1), 67-70 (2005-08-12) Reactive metabolites of 1,3-butadiene: DNA and hemoglobin adduct formation and potential roles in carcinogenicity.A A Elfarra et al.Advances in experimental medicine and biology, 500, 93-103 (2002-01-05) Advances in the mass spectrometry of hemoglobin adducts: global analysis of the covalent binding of butadiene monoxide.T S Moll et al.Chemico-biological interactions, 135-136, 667-674 (2001-06-09) Stereoselective ring expansion of vinyl oxiranes: mechanistic insights and natural product total synthesis.Matthew Brichacek et al.Angewandte Chemie (International ed. in English), 49(9), 1648-1651 (2010-02-06) Palladium-catalyzed DYKAT of butadiene monoepoxide: enantioselective total synthesis of (+)-DMDP, (-)-bulgecinine, and (+)-broussonetine G.Barry M Trost et al.Chemistry (Weinheim an der Bergstrasse, Germany), 12(25), 6607-6620 (2006-06-30) Synthesis of DNA oligodeoxynucleotides containing structurally defined N6-(2-hydroxy-3-buten-1-yl)-adenine adducts of 3,4-epoxy-1-butene.Danaè Quirk Dorr et al.Chemico-biological interactions, 166(1-3), 104-111 (2006-06-13) Mutagenicity of stereochemical configurations of 1,2-epoxybutene and 1,2:3,4-diepoxybutane in human lymphblastoid cells.Quanxin Meng et al.Chemico-biological interactions, 166(1-3), 207-218 (2006-07-21) Quantitative analysis of N-terminal valine peptide adducts specific for 1,2-epoxy-3-butene.Nadia I Georgieva et al.Chemico-biological interactions, 166(1-3), 219-225 (2006-07-25) Copper-catalyzed rearrangement of vinyl oxiranes.Lindsay A Batory et al.Journal of the American Chemical Society, 128(50), 16054-16055 (2006-12-15) Inhibitory potency of 4-carbon alkanes and alkenes toward CYP2E1 activity.Jessica H Hartman et al.Toxicology, 318, 51-58 (2014-02-25) Hemoglobin adducts and micronuclei in rodents after treatment with isoprene monoxide or butadiene monoxide.Charlotta Fred et al.Mutation research, 585(1-2), 21-32 (2005-06-01) Alternative reagents for chemical noise reduction in liquid chromatography-mass spectrometry using selective ion-molecule reactions.Xinghua Guo et al.Journal of the American Society for Mass Spectrometry, 20(1), 105-111 (2008-10-25) Dose responses for DNA adduct formation in tissues of rats and mice exposed by inhalation to low concentrations of 1,3-[2,3-[(14)C]-butadiene.Ewan D Booth et al.Chemico-biological interactions, 147(2), 195-211 (2004-03-12)
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