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N-(2,6-Dimethylphenyl)-4-methylbenzenesulfonamide | CAS:4703-15-5
N-(2,6-Dimethylphenyl)-4-methylbenzenesulfonamide
  • 名称:N-(2,6-二甲基苯基)-4-甲基苯磺酰胺 | N-(2,6-Dimethylphenyl)-4-methylbenzenesulfonamide
  • CAS号:4703-15-5
  • 别名:N-(p-Toluenesulfonyl)-2,6-dimethylaniline; N-Tosyl-2,6-dimethylaniline; NSC 97146
  • 分子式:C15H17NO2S
  • 分子量:275.37
  • EINESC号:

产品描述

物理化学性质

熔点 137 ºC (ethanol )**
密度 1.211±0.06 g/cm3 (20 º

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来源 SDS样本
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Induction of neuronal damage in guinea pig brain by intratracheal infusion of 2-chloroethyl ethyl sulfide, a mustard gas analog.Jessica Gadsden-Gray et al.Journal of biochemical and molecular toxicology, 26(1), 23-30 (2011-09-08) Tissue factor pathway inhibitor prevents airway obstruction, respiratory failure and death due to sulfur mustard analog inhalation.Raymond C Rancourt et al.Toxicology and applied pharmacology, 272(1), 86-95 (2013-06-04) Biological and molecular mechanisms of sulfur mustard analogue-induced toxicity in JB6 and HaCaT cells: possible role of ataxia telangiectasia-mutated/ataxia telangiectasia-Rad3-related cell cycle checkpoint pathway.Neera Tewari-Singh et al.Chemical research in toxicology, 23(6), 1034-1044 (2010-05-18) Airway tissue factor-dependent coagulation activity in response to sulfur mustard analog 2-chloroethyl ethyl sulfide.Raymond C Rancourt et al.American journal of physiology. Lung cellular and molecular physiology, 302(1), L82-L92 (2011-10-04) The immunomodulatory effects of mesenchymal stem cells on long term pulmonary complications in an animal model exposed to a sulfur mustard analog.Somaye Sadeghi et al.International immunopharmacology, 80, 105879-105879 (2019-11-27) Detection of vesicant-induced upper airway mucosa damage in the hamster cheek pouch model using optical coherence tomography.Marie J Hammer-Wilson et al.Journal of biomedical optics, 15(1), 016017-016017 (2010-03-10) Ameliorating effect of S-2(ω-aminoalkylamino) alkylaryl sulfide (DRDE-07) on sulfur mustard analogue, 2-chloroethyl ethyl sulfide-induced oxidative stress and inflammation.Shekhar D Sawale et al.Toxicology mechanisms and methods, 23(9), 702-710 (2013-09-13) Investigation of anticholinergic and non-steroidal anti-inflammatory prodrugs which reduce chemically induced skin inflammation.Sherri C Young et al.Journal of applied toxicology : JAT, 32(2), 135-141 (2011-02-15) Modified immunoslotblot assay to detect hemi and sulfur mustard DNA adducts.Kai Kehe et al.Chemico-biological interactions, 206(3), 523-528 (2013-08-13) Sulfur mustard analog, 2-chloroethyl ethyl sulfide-induced skin injury involves DNA damage and induction of inflammatory mediators, in part via oxidative stress, in SKH-1 hairless mouse skin.Anil K Jain et al.Toxicology letters, 205(3), 293-301 (2011-07-05) Selective targeting of selenocysteine in thioredoxin reductase by the half mustard 2-chloroethyl ethyl sulfide in lung epithelial cells.Yi-Hua Jan et al.Chemical research in toxicology, 23(6), 1045-1053 (2010-03-30) Research on the interaction of hydrogen-bond acidic polymer sensitive sensor materials with chemical warfare agents simulants by inverse gas chromatography.Liu Yang et al.Sensors (Basel, Switzerland), 15(6), 12884-12890 (2015-06-05) Protection against 2-chloroethyl ethyl sulfide (CEES)-induced cytotoxicity in human keratinocytes by an inducer of the glutathione detoxification pathway.Erika L Abel et al.Toxicology and applied pharmacology, 255(2), 176-183 (2011-07-05) Comparative toxicity of mono- and bifunctional alkylating homologues of sulphur mustard in human skin keratinocytes.Thomas W Sawyer et al.Toxicology, 382, 36-46 (2017-03-13) Efficacy of scalp hair decontamination following exposure to vapours of sulphur mustard simulants 2-chloroethyl ethyl sulphide and methyl salicylate.Marie Spiandore et al.Chemico-biological interactions, 267, 74-79 (2016-08-06) An improved method for retrospective quantification of sulfur mustard exposure by detection of its albumin adduct using ultra-high pressure liquid chromatography-tandem mass spectrometry.ChangCai Liu et al.Analytical and bioanalytical chemistry, 407(23), 7037-7046 (2015-07-15) 2,6-Dithiopurine, a nucleophilic scavenger, protects against mutagenesis in mouse skin treated in vivo with 2-(chloroethyl) ethyl sulfide, a mustard gas analog.Stephen Boulware et al.Toxicology and applied pharmacology, 263(2), 203-209 (2012-06-27) Mechanisms of Skin Toxicity Associated with Metabotropic Glutamate Receptor 5 Negative Allosteric Modulators.Falgun Shah et al.Cell chemical biology, 24(7), 858-869 (2017-07-04) Facility monitoring of chemical warfare agent simulants in air using an automated, field-deployable, miniature mass spectrometer.Jonell N Smith et al.Rapid communications in mass spectrometry : RCM, 25(10), 1437-1444 (2011-04-20) Extracellular nucleic acid scavenging rescues rats from sulfur mustard analog-induced lung injury and mortality.Nithya Mariappan et al.Archives of toxicology, 94(4), 1321-1334 (2020-03-12) Physics-based agent to simulant correlations for vapor phase mass transport.Matthew P Willis et al.Journal of hazardous materials, 263 Pt 2, 479-485 (2013-11-15) Metabolism of F18, a Derivative of Calanolide A, in Human Liver Microsomes and Cytosol.Xiangmeng Wu et al.Frontiers in pharmacology, 8, 479-479 (2017-08-05) Inhibition of NADPH cytochrome P450 reductase by the model sulfur mustard vesicant 2-chloroethyl ethyl sulfide is associated with increased production of reactive oxygen species.Joshua P Gray et al.Toxicology and applied pharmacology, 247(2), 76-82 (2010-06-22) Analysis of chemical warfare agents by portable Raman spectrometer with both 785nm and 1064nm excitation.Tomohide Kondo et al.Forensic science international, 291, 23-38 (2018-08-21) Role of TNFR1 in lung injury and altered lung function induced by the model sulfur mustard vesicant, 2-chloroethyl ethyl sulfide.Vasanthi R Sunil et al.Toxicology and applied pharmacology, 250(3), 245-255 (2010-11-13) Antioxidant liposomes protect against CEES-induced lung injury by decreasing SAF-1/MAZ-mediated inflammation in the guinea pig lung.Sutapa Mukhopadhyay et al.Journal of biochemical and molecular toxicology, 24(3), 187-194 (2010-06-29) Silibinin attenuates sulfur mustard analog-induced skin injury by targeting multiple pathways connecting oxidative stress and inflammation.Neera Tewari-Singh et al.PloS one, 7(9), e46149-e46149 (2012-10-03) Ion mobility spectrometers and electron capture detector - A comparison of detection capabilities.Edyta Budzyńska et al.Talanta, 194, 259-265 (2019-01-06) Antifibrinolytic mechanisms in acute airway injury after sulfur mustard analog inhalation.Raymond C Rancourt et al.American journal of respiratory cell and molecular biology, 51(4), 559-567 (2014-05-07) A mass spectrometric platform for the quantitation of sulfur mustard-induced nucleic acid adducts as mechanistically relevant biomarkers of exposure.Tabea Zubel et al.Archives of toxicology, 93(1), 61-79 (2018-10-17) Role of reactive oxygen and nitrogen species in olfactory epithelial injury by the sulfur mustard analogue 2-chloroethyl ethyl sulfide.Heidi C O'Neill et al.American journal of respiratory cell and molecular biology, 45(2), 323-331 (2011-06-07) The influence of N-acetyl-L-cysteine on oxidative stress and nitric oxide synthesis in stimulated macrophages treated with a mustard gas analogue.Victor Paromov et al.BMC cell biology, 9, 33-33 (2008-06-24) Sodium pyruvate modulates cell death pathways in HaCaT keratinocytes exposed to half-mustard gas.Victor Paromov et al.International journal of toxicology, 30(2), 197-206 (2011-02-09) Treatment with the catalytic metalloporphyrin AEOL 10150 reduces inflammation and oxidative stress due to inhalation of the sulfur mustard analog 2-chloroethyl ethyl sulfide.Heidi C O'Neill et al.Free radical biology & medicine, 48(9), 1188-1196 (2010-02-09) Significance of porous structure on degradatin of 2,2' dichloro diethyl sulphide and 2 chloroethyl ethyl sulphide on the surface of vanadium oxide nanostructure.Beer Singh et al.Journal of hazardous materials, 190(1-3), 1053-1057 (2011-03-30) Efficacy of glutathione in ameliorating sulfur mustard analog-induced toxicity in cultured skin epidermal cells and in SKH-1 mouse skin in vivo.Neera Tewari-Singh et al.The Journal of pharmacology and experimental therapeutics, 336(2), 450-459 (2010-10-27) Expression of proliferative and inflammatory markers in a full-thickness human skin equivalent following exposure to the model sulfur mustard vesicant, 2-chloroethyl ethyl sulfide.Adrienne T Black et al.Toxicology and applied pharmacology, 249(2), 178-187 (2010-09-16) Role of reactive nitrogen species generated via inducible nitric oxide synthase in vesicant-induced lung injury, inflammation and altered lung functioning.Vasanthi R Sunil et al.Toxicology and applied pharmacology, 261(1), 22-30 (2012-03-27) Mechanisms of sulfur mustard analog 2-chloroethyl ethyl sulfide-induced DNA damage in skin epidermal cells and fibroblasts.Swetha Inturi et al.Free radical biology & medicine, 51(12), 2272-2280 (2011-09-17) 2-Chloroethyl ethyl sulfide causes microvesication and inflammation-related histopathological changes in male hairless mouse skin.Anil K Jain et al.Toxicology, 282(3), 129-138 (2011-02-08) Inhibition of inducible Nitric Oxide Synthase by a mustard gas analog in murine macrophages.Min Qui et al.BMC cell biology, 7, 39-39 (2006-12-02) Intratracheal heparin improves plastic bronchitis due to sulfur mustard analog.Paul R Houin et al.Pediatric pulmonology, 50(2), 118-126 (2014-04-03) Regulation of Hsp27 and Hsp70 expression in human and mouse skin construct models by caveolae following exposure to the model sulfur mustard vesicant, 2-chloroethyl ethyl sulfide.Adrienne T Black et al.Toxicology and applied pharmacology, 253(2), 112-120 (2011-04-05) Sulforaphane induces phase II detoxication enzymes in mouse skin and prevents mutagenesis induced by a mustard gas analog.E L Abel et al.Toxicology and applied pharmacology, 266(3), 439-442 (2012-12-04)
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