询 单
请 填 写 相 关 信 息
产品信息
产品名称
别名
CAS号
结构式 上传
联系方式
公司
联系人
电话
邮箱
内容
提交
中文版 English
请输入产品名称、CAS式、分子式
(+)-Griseofulvin | CAS:126-07-8
(+)-Griseofulvin
  • 名称:(+)-灰黄霉素; 6'-甲基-2',4,6-三甲氧基-7-氯螺[苯并呋喃-2(3H),1'-[2]环己烯]-3,4'-二酮 | (+)-Griseofulvin
  • CAS号:126-07-8
  • 别名:(2S)-trans-7-Chloro-2',4,6-trimethoxy-6'-methylspiro(benzofuran-2[3H],1'-[2]cyclohexene)-3,4'-dione
  • 分子式:C17H17ClO6
  • 分子量:352.77
  • EINESC号:204-767-4

产品描述

物理化学性质

熔点 217-224 ºC
比旋光度 354 º (c=1, dimethylform)
水溶性 几乎不溶

安全数据

危险品标志 T
危险类别码 R60;R61;R40;R43
安全说明书 S53;S22;S36/37/39;S45

SDS

来源 SDS样本
没有数据没有数据
产品合成路线
更多

名称 CAS号
更多
文章
同行评议文献
Nuclear Entry of CRTC1 as Druggable Target of Acquired Pigmentary Disorder.Cheong-Yong Yun et al.Theranostics, 9(3), 646-660 (2019-02-28) Egr2-guided histone H2B monoubiquitination is required for peripheral nervous system myelination.Hannah M Wüst et al.Nucleic acids research, 48(16), 8959-8976 (2020-07-17) Minocycline inhibits D-amphetamine-elicited action potential bursts in a central snail neuron.Y-H Chen et al.Neuroscience, 223, 412-428 (2012-06-30) Hsv-1 Endocytic Entry into a Human Oligodendrocytic Cell Line is Mediated by Clathrin and Dynamin but Not Caveolin.Beatriz Praena et al.Viruses, 12(7) (2020-07-11) Renin knockout rat: control of adrenal aldosterone and corticosterone synthesis in vitro and adrenal gene expression.Hershel Raff et al.American journal of physiology. Regulatory, integrative and comparative physiology, 308(1), R73-R77 (2014-11-15) Combined Experimental and System-Level Analyses Reveal the Complex Regulatory Network of miR-124 during Human Neurogenesis.Lisa K Kutsche et al.Cell systems, 7(4), 438-452 (2018-10-08) The atypical Guanine-nucleotide exchange factor, dock7, negatively regulates schwann cell differentiation and myelination.Junji Yamauchi et al.The Journal of neuroscience : the official journal of the Society for Neuroscience, 31(35), 12579-12592 (2011-09-02) Circadian changes in long noncoding RNAs in the pineal gland.Steven L Coon et al.Proceedings of the National Academy of Sciences of the United States of America, 109(33), 13319-13324 (2012-08-07) Structure-function relationships of HDL in diabetes and coronary heart disease.Mathias Cardner et al.JCI insight, 5(1) (2019-12-13) Amidic derivatives of valproic acid, valpromide and valnoctamide, inhibit HSV-1 infection in oligodendrocytes.B Praena et al.Antiviral research, 168, 91-99 (2019-05-28) Transcriptional control of cell cycle-dependent kinase 4 by Smad proteins--implications for Alzheimer's disease.Uwe Ueberham et al.Neurobiology of aging, 33(12), 2827-2840 (2012-03-16) cAMP stimulates the ubiquitin/proteasome pathway in rat spinal cord neurons.Natura Myeku et al.Neuroscience letters, 527(2), 126-131 (2012-09-18) Effects of β₂-agonists on force during and following anoxia in rat extensor digitorum longus muscle.A Fredsted et al.Journal of applied physiology (Bethesda, Md. : 1985), 112(12), 2057-2067 (2012-04-12) Blood Outgrowth Endothelial Cells as a Cellular Carrier for Oncolytic Vesicular Stomatitis Virus Expressing Interferon-β in Preclinical Models of Non-Small Cell Lung Cancer.Manish R Patel et al.Translational oncology, 13(7), 100782-100782 (2020-05-19) Human-iPSC-Derived Cardiac Stromal Cells Enhance Maturation in 3D Cardiac Microtissues and Reveal Non-cardiomyocyte Contributions to Heart Disease.Elisa Giacomelli et al.Cell stem cell, 26(6), 862-879 (2020-05-28) Implication of multiple signaling pathways in the regulation of angiotensin II induced enhanced expression of Giα proteins in vascular smooth muscle cells.Yuan Li et al.Canadian journal of physiology and pharmacology, 90(8), 1105-1116 (2012-07-13) Premature polyadenylation-mediated loss of stathmin-2 is a hallmark of TDP-43-dependent neurodegeneration.Ze'ev Melamed et al.Nature neuroscience, 22(2), 180-190 (2019-01-16) Calpain-1 knockout reveals broad effects on erythrocyte deformability and physiology.Adam Wieschhaus et al.The Biochemical journal, 448(1), 141-152 (2012-08-09) Immature mDA neurons ameliorate motor deficits in a 6-OHDA Parkinson's disease mouse model and are functional after cryopreservation.Dominique Leitner et al.Stem cell research, 41, 101617-101617 (2019-11-16) Transcriptome Engineering with RNA-Targeting Type VI-D CRISPR Effectors.Silvana Konermann et al.Cell, 173(3), 665-676 (2018-03-20) Activity of translation regulator eukaryotic elongation factor-2 kinase is increased in Parkinson disease brain and its inhibition reduces alpha synuclein toxicity.Asad Jan et al.Acta neuropathologica communications, 6(1), 54-54 (2018-07-03) Glutamate-glutamine homeostasis is perturbed in neurons and astrocytes derived from patient iPSC models of frontotemporal dementia.Blanca I Aldana et al.Molecular brain, 13(1), 125-125 (2020-09-16) Mechanisms of action of hormone-sensitive lipase in mouse Leydig cells: its role in the regulation of the steroidogenic acute regulatory protein.Pulak R Manna et al.The Journal of biological chemistry, 288(12), 8505-8518 (2013-01-31) Transplantation of human retinal pigment epithelium cells in the treatment for Parkinson disease.Feng Yin et al.CNS neuroscience & therapeutics, 18(12), 1012-1020 (2012-11-30) Phosphorylation of cortactin by cyclin-dependent kinase 5 modulates actin bundling by the dynamin 1-cortactin ring-like complex and formation of filopodia and lamellipodia in NG108-15 glioma-derived cells.Tadashi Abe et al.International journal of oncology, 54(2), 550-558 (2018-12-21) Uric acid-dependent inhibition of AMP kinase induces hepatic glucose production in diabetes and starvation: evolutionary implications of the uricase loss in hominids.Christina Cicerchi et al.FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 28(8), 3339-3350 (2014-04-24) cAMP-mediated stabilization of fusion pores in cultured rat pituitary lactotrophs.Ana Isabel Calejo et al.The Journal of neuroscience : the official journal of the Society for Neuroscience, 33(18), 8068-8078 (2013-05-03) Angiotensin-(1-7) in paraventricular nucleus modulates sympathetic activity and cardiac sympathetic afferent reflex in renovascular hypertensive rats.Ying Han et al.PloS one, 7(11), e48966-e48966 (2012-11-10) Downregulation of PMCA2 or PMCA3 reorganizes Ca(2+) handling systems in differentiating PC12 cells.Tomasz Boczek et al.Cell calcium, 52(6), 433-444 (2012-08-28) Dynamic alterations in the expression and localization of ACTL7a during capacitation in mouse spermatozoa.Jun Fu et al.Fertility and sterility, 99(3), 882-888 (2012-12-06) cAMP prevents TNF-induced apoptosis through inhibiting DISC complex formation in rat hepatocytes.Rajesh Bhattacharjee et al.Biochemical and biophysical research communications, 423(1), 85-90 (2012-05-29) Fish Macrophages Show Distinct Metabolic Signatures Upon Polarization.Annelieke S Wentzel et al.Frontiers in immunology, 11, 152-152 (2020-03-12) Macrophage mitochondrial damage from StAR transport of 7-hydroperoxycholesterol: implications for oxidative stress-impaired reverse cholesterol transport.Witold Korytowski et al.FEBS letters, 588(1), 65-70 (2013-11-26) Alpha7 nicotinic acetylcholine receptors and neural network synaptic transmission in human induced pluripotent stem cell-derived neurons.Hjalte M Larsen et al.Stem cell research, 41, 101642-101642 (2019-11-11) Insulin-like growth factor 1 partially rescues early developmental defects caused by SHANK2 knockdown in human neurons.Shu-Ting Chen et al.Neural regeneration research, 15(12), 2335-2343 (2020-07-01) TC-E 5003, a protein methyltransferase 1 inhibitor, activates the PKA-dependent thermogenic pathway in primary murine and human subcutaneous adipocytes.Min-Jung Park et al.FEBS letters, 594(17), 2923-2930 (2020-08-09) Embryotoxic impact of Zika virus in a rhesus macaque in vitro implantation model†.Lindsey N Block et al.Biology of reproduction, 102(4), 806-816 (2020-01-05) Mechanisms of carbon monoxide attenuation of tubuloglomerular feedback.Yilin Ren et al.Hypertension (Dallas, Tex. : 1979), 59(6), 1139-1144 (2012-04-18) Roles of promoter and 3' untranslated motifs in expression of the human C5a receptor.Elizabeth Palmer et al.Molecular immunology, 52(2), 88-95 (2012-05-23) FTO Intronic SNP Strongly Influences Human Neck Adipocyte Browning Determined by Tissue and PPARγ Specific Regulation: A Transcriptome Analysis.Beáta B Tóth et al.Cells, 9(4) (2020-04-23) Cell Type-Specific In Vitro Gene Expression Profiling of Stem Cell-Derived Neural Models.James A Gregory et al.Cells, 9(6) (2020-06-11) H4 histamine receptors inhibit steroidogenesis and proliferation in Leydig cells.Adriana María Belén Abiuso et al.The Journal of endocrinology, 223(3), 241-253 (2014-09-26) Action of db-cAMP on the bystander effect and chemosensitivity through connexin 43 and Bcl-2-mediated pathways in medulloblastoma cells.Peixin Sun et al.Oncology reports, 28(3), 969-976 (2012-07-07) [Cellular and molecular mechanisms in drug-induced nephrotoxicity and its prevention].Takahisa Yano Nihon yakurigaku zasshi. Folia pharmacologica Japonica, 142(4), 172-177 (2013-10-11) A Tissue-Engineered 3D Microvessel Model Reveals the Dynamics of Mosaic Vessel Formation in Breast Cancer.Vanesa L Silvestri et al.Cancer research, 80(19), 4288-4301 (2020-07-16) Absence of the long noncoding RNA H19 results in aberrant ovarian STAR and progesterone production.Yong Chen et al.Molecular and cellular endocrinology, 490, 15-20 (2019-03-30) Mps one binder 2 gene upregulation in the stellation of astrocytes induced by cAMP-dependent pathway.Kuan-Min Fang et al.Journal of cellular biochemistry, 113(9), 3019-3028 (2012-05-09) Defective protein kinase A and C pathways are common causes of disordered zona pellucida (ZP)--induced acrosome reaction in normozoospermic infertile men with normal sperm-ZP binding.De-Yi Liu et al.Fertility and sterility, 99(1), 86-91 (2012-09-19) Nitrite Protects Neurons Against Hypoxic Damage Through S-nitrosylation of Caspase-6.Yen-Jung Chen et al.Antioxidants & redox signaling, 31(2), 109-126 (2018-11-13) Differentiation and maturation of oligodendrocytes in human three-dimensional neural cultures.Rebecca M Marton et al.Nature neuroscience, 22(3), 484-491 (2019-01-30) Transcriptome sequencing supports a conservation of macrophage polarization in fish.Annelieke S Wentzel et al.Scientific reports, 10(1), 13470-13470 (2020-08-12) Extracellular ATP induces intracellular alpha-synuclein accumulation via P2X1 receptor-mediated lysosomal dysfunction.Ming Gan et al.Neurobiology of aging, 36(2), 1209-1220 (2014-12-07) Critical period for dopaminergic neuroprotection by hormonal replacement in menopausal rats.Ana I Rodriguez-Perez et al.Neurobiology of aging, 36(2), 1194-1208 (2014-11-30) Analysis of Motor Neurons Differentiated from Human Induced Pluripotent Stem Cells for the Use in Cell-Based Botulinum Neurotoxin Activity Assays.Maren Schenke et al.Toxins, 12(5) (2020-04-30) HeLa human cervical cancer cell migration is inhibited by treatment with dibutyryl-cAMP.Jae-Wook Lee et al.Anticancer research, 34(7), 3447-3455 (2014-07-02) The secretogranin II gene is a signal integrator of glutamate and dopamine inputs.Katsuro Iwase et al.Journal of neurochemistry, 128(2), 233-245 (2013-10-12) Tulp3 Regulates Renal Cystogenesis by Trafficking of Cystoproteins to Cilia.Sun-Hee Hwang et al.Current biology : CB, 29(5), 790-802 (2019-02-26) Clearance of activity-evoked K+ transients and associated glia cell swelling occur independently of AQP4: A study with an isoform-selective AQP4 inhibitor.Trine Lisberg Toft-Bertelsen et al.Glia, 69(1), 28-41 (2020-06-09) Inhibition of the microglial response is essential for the neuroprotective effects of Rho-kinase inhibitors on MPTP-induced dopaminergic cell death.Ana Borrajo et al.Neuropharmacology, 85, 1-8 (2014-06-01) Moderate superoxide production is an early promoter of mitochondrial biogenesis in differentiating N2a neuroblastoma cells.T Valero et al.Neurochemistry international, 61(8), 1333-1343 (2012-10-02) Differential expression of the 5-HT(3A) and 5-HT(3B) receptor in differentiated NG108-15 cells.Hajime Asano et al.Neurochemical research, 37(8), 1738-1746 (2012-04-27) Regulatory mechanisms of acetylcholine synthesis and release by T cells.Takeshi Fujii et al.Life sciences, 91(21-22), 981-985 (2012-05-10) β-Adrenergic stimulation increases Cav3.1 activity in cardiac myocytes through protein kinase A.Yingxin Li et al.PloS one, 7(7), e39965-e39965 (2012-07-19) Regulation of NADPH oxidase gene expression with PKA and cytokine IL-4 in neurons and microglia.Valentina L Savchenko Neurotoxicity research, 23(3), 201-213 (2012-05-09) Pre-conditioning induces the precocious differentiation of neonatal astrocytes to enhance their neuroprotective properties.Sen E, Basu A, Willing LB, et al. ASN Neuro, 26 (2011) Forskolin increases neuregulin receptors in human Schwann cells without increasing receptor mRNA.Nevis L Fregien et al.Glia, 49(1), 24-35 (2004-09-25) Distinct VIP and PACAP Functions in the Distal Nerve Stump During Peripheral Nerve Regeneration.Patricia K Woodley et al.Frontiers in neuroscience, 13, 1326-1326 (2020-01-11) Transient Internalization and Microtubule-Dependent Trafficking of a Ciliary Signaling Receptor from the Plasma Membrane to the Cilium.Peeyush Ranjan et al.Current biology : CB, 29(17), 2942-2947 (2019-08-20) GATA6 and FOXA2 regulate Wnt6 expression during extraembryonic endoderm formation.Jason T K Hwang et al.Stem cells and development, 21(17), 3220-3232 (2012-05-23) Interaction between nonviral reprogrammed fibroblast stem cells and trophic factors for brain repair.G Liu et al.Molecular neurobiology, 50(2), 673-684 (2014-03-29) Cerebrospinal fluid levels of a 20-22 kDa NH2 fragment of human tau provide a novel neuronal injury biomarker in Alzheimer's disease and other dementias.Giuseppina Amadoro et al.Journal of Alzheimer's disease : JAD, 42(1), 211-226 (2014-05-24) Bradykinin inhibits the transient outward K+ current in mouse Schwann cells via the cAMP/PKA pathway.Man Zhang et al.American journal of physiology. Cell physiology, 296(6), C1364-C1372 (2009-04-03)
备注

Products protected by valid patents are not offered for sale in countries where the sale of such products constitutes a patent infringement and its liability is at buyer's risk.

Products currently covered by valid US Patents are offered for R&D use in accordance with 35 USC 271 +A13(1).

名称 CAS号

相关产品

相关资讯

热门标签
询 单
请 填 写 相 关 信 息
产品信息
产品名称
别名
CAS号
结构式 上传
联系方式
公司
联系人
电话
邮箱
内容
提交