熔点	-79 ºC
水溶性	0.6 g/100 mL
沸点	289 ºC
闪点	146 ºC
密度	0.979
折射率	1.423-1.425

危险品标志	Xn
危险类别码	R22;R38;R40
安全说明书	S36/37;S46

来源	SDS样本
没有数据	没有数据

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Microbial hydroxylation of sclareol by Rhizopus stolonifer.D Díez et al.Molecules (Basel, Switzerland), 10(8), 1005-1009 (2007-11-17) Bioactive constituents of Salvia chrysophylla Stapf.Burcu Çulhaoğlu et al.Natural product research, 27(4-5), 438-447 (2012-11-07) Cytotoxic and antitumor activity of liposome-incorporated sclareol against cancer cell lines and human colon cancer xenografts.Sophia Hatziantoniou et al.Pharmacological research, 53(1), 80-87 (2005-10-29) Sclareol induces apoptosis in human HCT116 colon cancer cells in vitro and suppression of HCT116 tumor growth in immunodeficient mice.Konstantinos Dimas et al.Apoptosis : an international journal on programmed cell death, 12(4), 685-694 (2007-01-30) Fragrance material review on sclareol.S P Bhatia et al.Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 46 Suppl 11, S270-S274 (2008-07-22) Discovery and functional characterization of two diterpene synthases for sclareol biosynthesis in Salvia sclarea (L.) and their relevance for perfume manufacture.Caniard A, et al. BMC plant biology, 12(1), 119-119 (2012) First enantiospecific synthesis of the antitumor marine sponge metabolite (-)-15-oxopuupehenol from (-)-sclareol.E J Alvarez-Manzaneda et al.Organic letters, 7(8), 1477-1480 (2005-04-09) Parallel dual secondary column-dual detection: a further way of enhancing the informative potential of two-dimensional comprehensive gas chromatography.Luca Nicolotti et al.Journal of chromatography. A, 1360, 264-274 (2014-08-19) Antimicrobial evaluation of diterpenes from Copaifera langsdorffii oleoresin against periodontal anaerobic bacteria.Ariana B Souza et al.Molecules (Basel, Switzerland), 16(11), 9611-9619 (2011-11-22) Extracellular localization of the diterpene sclareol in clary sage (Salvia sclarea L., Lamiaceae).Jean-Claude Caissard et al.PloS one, 7(10), e48253-e48253 (2012-11-08) Sclareol exhibits anti-inflammatory activity in both lipopolysaccharide-stimulated macrophages and the λ-carrageenan-induced paw edema model.Guan-Jhong Huang et al.Journal of natural products, 75(1), 54-59 (2012-01-19) Antibacterial and cytotoxic activity of the acetone extract of the flowers of Salvia sclarea and some natural products.Edziri Hayet et al.Pakistan journal of pharmaceutical sciences, 20(2), 146-148 (2007-04-10) Toward a biosynthetic route to sclareol and amber odorants.Michel Schalk et al.Journal of the American Chemical Society, 134(46), 18900-18903 (2012-11-02) Sclareol modulates the Treg intra-tumoral infiltrated cell and inhibits tumor growth in vivo.Shokoofe Noori et al.Cellular immunology, 263(2), 148-153 (2010-04-23) Liposomes modify the subcellular distribution of sclareol uptake by HCT-116 cancer cell lines.Agnès Paradissis et al.Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 61(2-3), 120-124 (2007-02-03) Mitochondria-targeted liposomes improve the apoptotic and cytotoxic action of sclareol.Niravkumar R Patel et al.Journal of liposome research, 20(3), 244-249 (2009-11-04) Structure elucidation and antibacterial activity of new fungal metabolites of sclareol.M Iqbal Choudhary et al.Chemistry & biodiversity, 3(1), 54-61 (2006-12-29) Conversion of sclareol into (+)-galanolactone and (+)-labdienedial.Jung M, et al. Tetrahedron Letters, 38(16), 2871-2874 (1997) A short efficient synthesis of ambraketal (four steps) and epiambraketal (five steps) from Sclareol.Martres P, et al. Tetrahedron Letters, 35(1), 97-98 (1994) Structure elucidation and antibacterial activity of new fungal metabolites of sclareol.M Iqbal Choudhary et al.Chemistry & biodiversity, 3(1), 54-61 (2006-12-29) Mitochondria-targeted liposomes improve the apoptotic and cytotoxic action of sclareol.Niravkumar R Patel et al.Journal of liposome research, 20(3), 244-249 (2009-11-04) Liposomes modify the subcellular distribution of sclareol uptake by HCT-116 cancer cell lines.Agnès Paradissis et al.Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 61(2-3), 120-124 (2007-02-03) Discovery and functional characterization of two diterpene synthases for sclareol biosynthesis in Salvia sclarea (L.) and their relevance for perfume manufacture.Anne Caniard et al.BMC plant biology, 12, 119-119 (2012-07-28) The labdane diterpene sclareol (labd-14-ene-8, 13-diol) induces apoptosis in human tumor cell lines and suppression of tumor growth in vivo via a p53-independent mechanism of action.Louisa G Mahaira et al.European journal of pharmacology, 666(1-3), 173-182 (2011-05-31) The effect of sclareol on growth and cell cycle progression of human leukemic cell lines.Dimas K, et al. Leukemia Research, 23(3), 217-234 (1999) Hemisynthesis of two marine cheilanthane sesterterpenes from (-)-sclareol: first enantioselective synthesis of petrosaspongiolide R.Leticia Ferreiro-Mederos et al.Natural product research, 23(3), 256-263 (2009-02-24) NpPDR1, a pleiotropic drug resistance-type ATP-binding cassette transporter from Nicotiana plumbaginifolia, plays a major role in plant pathogen defense.Yvan Stukkens et al.Plant physiology, 139(1), 341-352 (2005-08-30) Synthesis of ambergris fragrance chemicals from sclareol, involving palladium catalysed key steps.Coste-Maniere IC, et al. Tetrahedron Letters, 29(9), 1017-1020 (1988) Hemisynthesis of new labdane derivatives from (-)-sclareol.Abdel Waheb Fekih et al.Natural product research, 20(10), 887-895 (2006-07-21) Identification of natural diterpenes that inhibit bacterial wilt disease in tobacco, tomato and Arabidopsis.Shigemi Seo et al.Plant & cell physiology, 53(8), 1432-1444 (2012-06-12) Sclareol-loaded lipid nanoparticles improved metabolic profile in obese mice.Gabriela Cavazza Cerri et al.Life sciences, 218, 292-299 (2019-01-06) Synthesis of ent-thallusin.Xiaolei Gao et al.Organic letters, 8(10), 2123-2126 (2006-05-05) Labdane diterpenoids from Salvia reuterana.Mahdi Moridi Farimani et al.Phytochemistry, 108, 264-269 (2014-09-23)

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