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Thioridazine hydrochloride | CAS:130-61-0
Thioridazine hydrochloride
  • 名称:盐酸硫利达嗪; 甲硫达嗪盐酸盐; 10-[2-(1-甲基-2-哌啶基)乙基]-2-(甲硫基)-10H-吩噻嗪盐酸盐 | Thioridazine hydrochloride
  • CAS号:130-61-0
  • 别名:10-[2-(1-Methyl-2-piperidyl)ethyl]-2-(methylthio)-10H-phenothiazine hydrochloride
  • 分子式:C21H26N2S2.HCl
  • 分子量:407.03
  • EINESC号:204-992-8

产品描述

物理化学性质

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安全数据

危险品标志 Xn;N
危险类别码 R22;R36/37/38;R50/53
安全说明书 S26;S36;S60;S61

SDS

来源 SDS样本
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Evaluation of Antibacterial Activity of 3?Butenyl, 4?Pentenyl, 2?Phenylethyl, and Benzyl Isothiocyanate in Brassica VegetablesJang M, et al. Journal of Food Science, 75(7) (2010) Phenethyl isothiocyanate-induced cytoskeletal changes and cell death in lung cancer cells.Andrzej Pawlik et al.Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 50(10), 3577-3594 (2012-08-01) Differential induction of apoptosis in human breast cancer cell lines by phenethyl isothiocyanate, a glutathione depleting agent.Sharifah S Syed Alwi et al.Cell stress & chaperones, 17(5), 529-538 (2012-02-22) Antitumor activity of phenethyl isothiocyanate in HER2-positive breast cancer models.Parul Gupta et al.BMC medicine, 10, 80-80 (2012-07-25) In vitro metabolic conversion of the organic breakdown products of glucosinolate to goitrogenic thiocyanate anion.Juyoung Lee et al.Journal of the science of food and agriculture, 95(11), 2244-2251 (2014-10-02) Macrophage migration inhibitory factor covalently complexed with phenethyl isothiocyanate.Joel D A Tyndall et al.Acta crystallographica. Section F, Structural biology and crystallization communications, 68(Pt 9), 999-1002 (2012-09-06) Effects of indole-3-carbinol and phenethyl isothiocyanate on bile and pancreatic juice excretion in rats.Hiroki Ishibashi et al.The journal of medical investigation : JMI, 59(3-4), 246-252 (2012-10-06) Inhibition of EGFR-AKT axis results in the suppression of ovarian tumors in vitro and in preclinical mouse model.Sivakumar Loganathan et al.PloS one, 7(8), e43577-e43577 (2012-09-07) Antibacterial activity and synergistic effect between watercress extracts, 2?phenylethyl isothiocyanate and antibiotics against 11 isolates of Escherichia coli from clinical and animal source.Freitas E, et al. Letters in Applied Microbiology, 57(4), 266-273 (2013) ID helix-loop-helix proteins as determinants of cell survival in B-cell chronic lymphocytic leukemia cells in vitro.Sarah Weiler et al.Molecular cancer, 14, 30-30 (2015-02-04) Isothiocyanates ameliorate the symptom of heart dysfunction and mortality in a murine AIDS model by inhibiting apoptosis in the left ventricle.Jin-Nyoung Ho et al.Journal of medicinal food, 15(9), 781-787 (2012-08-29) Differential effects of phenethyl isothiocyanate and D,L-sulforaphane on TLR3 signaling.Jianzhong Zhu et al.Journal of immunology (Baltimore, Md. : 1950), 190(8), 4400-4407 (2013-03-20) Molecular and life-history effects of a natural toxin on herbivorous and non-target soil arthropods.A E Elaine van Ommen Kloeke et al.Ecotoxicology (London, England), 21(4), 1084-1093 (2012-02-09) Chaetocin antileukemia activity against chronic myelogenous leukemia cells is potentiated by bone marrow stromal factors and overcomes innate imatinib resistance.L Truitt et al.Oncogenesis, 3, e122-e122 (2014-10-21) Phenethyl isothiocyanate regulates inflammation through suppression of the TRIF-dependent signaling pathway of Toll-like receptors.Park HJ, Kim SJ, Park SJ, et al. Life Sciences, 92(13), 793-798 (2013) Phenethyl isothiocyanate, a naturally occurring phytochemical, is an antagonist of the aryl hydrocarbon receptor.Ahmad F Abdull Razis et al.Molecular nutrition & food research, 56(3), 425-434 (2011-12-17) Biomarkers of phenethyl isothiocyanate-mediated mammary cancer chemoprevention in a clinically relevant mouse model.Shivendra V Singh et al.Journal of the National Cancer Institute, 104(16), 1228-1239 (2012-08-04) Glutathionyl-hydroquinone reductases from poplar are plastidial proteins that deglutathionylate both reduced and oxidized glutathionylated quinones.Pierre-Alexandre Lallement et al.FEBS letters, 589(1), 37-44 (2014-12-03) β-phenylethyl isothiocyanate reverses platinum resistance by a GSH-dependent mechanism in cancer cells with epithelial-mesenchymal transition phenotype.Wen-jing Wu et al.Biochemical pharmacology, 85(4), 486-496 (2012-12-12) Proteomic analysis of covalent modifications of tubulins by isothiocyanates.Zhen Xiao et al.The Journal of nutrition, 142(7), 1377S-1381S (2012-06-01) Antibacterial activity and mode of action of selected glucosinolate hydrolysis products against bacterial pathogens.Anabela Borges et al.Journal of food science and technology, 52(8), 4737-4748 (2015-08-06) Reduced susceptibility of Brassica napus to Pratylenchus neglectus in plants with elevated root levels of 2-phenylethyl glucosinolate.Potter MJ, et al. Journal of Nematology, 31(3), 291-291 (1999) Development and application of a method for identification of isothiocyanate-targeted molecules in colon cancer cells.Noriyuki Miyoshi et al.Analytical biochemistry, 429(2), 124-131 (2012-07-28) Transcriptomic alterations in human prostate cancer cell LNCaP tumor xenograft modulated by dietary phenethyl isothiocyanate.Robert W Li et al.Molecular carcinogenesis, 52(6), 426-437 (2012-02-07) Natural product-derived antitumor compound phenethyl isothiocyanate inhibits mTORC1 activity via TSC2.Breeze E Cavell et al.Journal of natural products, 75(6), 1051-1057 (2012-05-23) Phenethyl isothiocyanate upregulates death receptors 4 and 5 and inhibits proliferation in human cancer stem-like cells.Dan Wang et al.BMC cancer, 14, 591-591 (2014-08-17) miR-141 modulates androgen receptor transcriptional activity in human prostate cancer cells through targeting the small heterodimer partner protein.Jing Xiao et al.The Prostate, 72(14), 1514-1522 (2012-02-09) Synthesis, DNA Binding, and Antiproliferative Activity of Novel Acridine-Thiosemicarbazone Derivatives.Sinara Mônica Vitalino de Almeida et al.International journal of molecular sciences, 16(6), 13023-13042 (2015-06-13) Time-related survival effects of two gluconasturtiin hydrolysis products on the terrestrial isopod Porcellio scaber.A E Elaine van Ommen Kloeke et al.Chemosphere, 89(9), 1084-1090 (2012-06-16) Aberrant activation of M phase proteins by cell proliferation-evoking carcinogens after 28-day administration in rats.Atsunori Yafune et al.Toxicology letters, 219(3), 203-210 (2013-03-29) Chemopreventive and anti-angiogenic effects of dietary phenethyl isothiocyanate in an N-methyl nitrosourea-induced breast cancer animal model.Urvi Aras et al.Biopharmaceutics & drug disposition, 34(2), 98-106 (2012-11-10) Effect of phenethyl isothiocyanate on Ca2+ movement and viability in MDCK canine renal tubular cells.I S Chen et al.Human & experimental toxicology, 31(12), 1251-1261 (2012-06-02) Prostate cancer chemopreventive activity of phenethyl isothiocyanate through epigenetic regulation (review).Long G Wang et al.International journal of oncology, 37(3), 533-539 (2010-07-29) Molecular targets of dietary phenethyl isothiocyanate and sulforaphane for cancer chemoprevention.Ka Lung Cheung et al.The AAPS journal, 12(1), 87-97 (2009-12-17) Tumor regression by phenethyl isothiocyanate involves DDB2.Nilotpal Roy et al.Cancer biology & therapy, 14(2), 108-116 (2012-11-02) β-Phenethyl isothiocyanate induces death receptor 5 to induce apoptosis in human oral cancer cells via p38.L D Huong et al.Oral diseases, 18(5), 513-519 (2012-02-09) In vitro inhibition of soil microorganisms by 2?phenylethyl isothiocyanate.Smith BJ & Kirkegaard JA Plant Pathology, 51(5), 585-593 (2002) Inhibition of androgen-responsive LNCaP prostate cancer cell tumor xenograft growth by dietary phenethyl isothiocyanate correlates with decreased angiogenesis and inhibition of cell attachment.Tamaro S Hudson et al.International journal of oncology, 40(4), 1113-1121 (2012-01-24)
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