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2,2',4,4'-Tetrahydroxybenzophenone | CAS:131-55-5
2,2',4,4'-Tetrahydroxybenzophenone
  • 名称:2,2',4,4'-四羟基二苯甲酮 | 2,2',4,4'-Tetrahydroxybenzophenone
  • CAS号:131-55-5
  • 别名:Di(2,4-dihydroxyphenyl)methanone; Bis(2,4-dihydroxyphenyl)methanone
  • 分子式:C13H10O5
  • 分子量:246.22
  • EINESC号:205-028-9

产品描述

物理化学性质

熔点 199-204 ºC

安全数据

危险品标志 Xn
危险类别码 R22;R36/37/38
安全说明书 S26;S37/39

SDS

来源 SDS样本
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high-performance liquid chromatography with electrospray ionization tandem mass spectrometry.Panpan Guo et al.Journal of separation science, 38(7), 1156-1163 (2015-01-27) [Studies on flavones from Flos Chrysanthemi Indici].Yi Tang et al.Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials, 32(10), 1532-1534 (2010-02-02) Bioactivity of diosmetin glycosides isolated from the epicarp of date fruits, Phoenix dactylifera, on the biochemical profile of alloxan diabetic male rats.Helana Naguib Michael et al.Phytotherapy research : PTR, 27(5), 699-704 (2012-07-05) Stimulatory constituents of Eclipta prostrata on mouse osteoblast differentiation.Mi Kyeong Lee et al.Phytotherapy research : PTR, 23(1), 129-131 (2008-08-08) Protective effects of diosmetin extracted from Galium verum L. on the thymus of U14-bearing mice.Rui Zhao et al.Canadian journal of physiology and pharmacology, 89(9), 665-673 (2011-08-20) 7-Hydroxy-benzopyran-4-one derivatives: a novel pharmacophore of peroxisome proliferator-activated receptor alpha and -gamma (PPARalpha and gamma) dual agonists.Azadeh Matin et al.Journal of medicinal chemistry, 52(21), 6835-6850 (2009-10-08) The flavonoids diosmetin and luteolin exert synergistic cytostatic effects in human hepatoma HepG2 cells via CYP1A-catalyzed metabolism, activation of JNK and ERK and P53/P21 up-regulation.Vasilis P Androutsopoulos et al.The Journal of nutritional biochemistry, 24(2), 496-504 (2012-07-04) Inhibition of cytochrome P450 2C8-mediated drug metabolism by the flavonoid diosmetin.Luigi Quintieri et al.Drug metabolism and pharmacokinetics, 26(6), 559-568 (2011-07-28) Selective inhibition of methoxyflavonoids on human CYP1B1 activity.Hitomi Takemura et al.Bioorganic & medicinal chemistry, 18(17), 6310-6315 (2010-08-11) The efflux of flavonoids morin, isorhamnetin-3-O-rutinoside and diosmetin-7-O-beta-D-xylopyranosyl-(1-6) -beta-D-glucopyranoside in the human intestinal cell line caco-2.Xiaojuan Tian et al.Pharmaceutical research, 23(8), 1721-1728 (2006-07-13) Iron deficiency enhances bioactive phenolics in lemon juice.Carmen D Mellisho et al.Journal of the science of food and agriculture, 91(12), 2132-2139 (2011-05-12) Quercitrin and taxifolin stimulate osteoblast differentiation in MC3T3-E1 cells and inhibit osteoclastogenesis in RAW 264.7 cells.María Satué et al.Biochemical pharmacology, 86(10), 1476-1486 (2013-09-26) Effect of diosmetin on airway remodeling in a murine model of chronic asthma.Ai Ge et al.Acta biochimica et biophysica Sinica, 47(8), 604-611 (2015-06-03) Flavonoid glycosides in bergamot juice (Citrus bergamia Risso).Giuseppe Gattuso et al.Journal of agricultural and food chemistry, 54(11), 3929-3935 (2006-05-25) Anticancer effects of the flavonoid diosmetin on cell cycle progression and proliferation of MDA-MB 468 breast cancer cells due to CYP1 activation.Vasilis P Androutsopoulos et al.Oncology reports, 21(6), 1525-1528 (2009-05-09) Flavonoids are inhibitors of human organic anion transporter 1 (OAT1)-mediated transport.Guohua An et al.Drug metabolism and disposition: the biological fate of chemicals, 42(9), 1357-1366 (2014-07-09) New features on the fragmentation and differentiation of C-glycosidic flavone isomers by positive electrospray ionization and triple quadrupole mass spectrometry.Beatriz Abad-García et al.Rapid communications in mass spectrometry : RCM, 22(12), 1834-1842 (2008-05-13) Different flavonoids present in the micronized purified flavonoid fraction (Daflon 500 mg) contribute to its anti-hyperpermeability effect in the hamster cheek pouch microcirculation.J Paysant et al.International angiology : a journal of the International Union of Angiology, 27(1), 81-85 (2008-02-16) Electrospinning of diosmin from aqueous solutions for improved dissolution and oral absorption.Petr Vrbata et al.International journal of pharmaceutics, 473(1-2), 407-413 (2014-07-30) Simultaneous determination of diosmin and diosmetin in human plasma by ion trap liquid chromatography-atmospheric pressure chemical ionization tandem mass spectrometry: Application to a clinical pharmacokinetic study.Miguel Angel Campanero et al.Journal of pharmaceutical and biomedical analysis, 51(4), 875-881 (2009-10-06) [Chemical constituents contained in seeds of Notopterygium franchetii].Yanxia Zhang et al.Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, 37(7), 941-945 (2012-07-17) Flavonoid glycosides inhibit oral cancer cell proliferation--role of cellular uptake and hydrolysis to the aglycones.Alyson M Browning et al.The Journal of pharmacy and pharmacology, 57(8), 1037-1042 (2005-08-17) Flavonoids diosmetin and hesperetin are potent inhibitors of cytochrome P450 2C9-mediated drug metabolism in vitro.Luigi Quintieri et al.Drug metabolism and pharmacokinetics, 25(5), 466-476 (2010-09-30) Comparative CYP1A1 and CYP1B1 substrate and inhibitor profile of dietary flavonoids.Vasilis P Androutsopoulos et al.Bioorganic & 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