1,6-Naphthyridine | CAS:253-72-5
1,6-Naphthyridine
- 名称:1,6-二氮萘; 1,6-二氮杂萘; 1,6-萘啶 | 1,6-Naphthyridine
- CAS号:253-72-5
- 别名:
- 分子式:C8H6N2
- 分子量:130.15
- EINESC号:
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Evaluation of rumen temperature as a novel indicator of meat quality: Rumen temperature and haematological indicators of stress during the pre-slaughter period as predictors of instrumental meat quality in bulls.N H Rutherford et al.Meat science, 158, 107913-107913 (2019-08-21)
The neuroprotective effect of nicotine in Parkinson's disease models is associated with inhibiting PARP-1 and caspase-3 cleavage.Justin Y D Lu et al.PeerJ, 5, e3933-e3933 (2017-10-25)
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Robust Neuritogenesis-Promoting Activity by Bis(heptyl)-Cognitin Through the Activation of alpha7-Nicotinic Acetylcholine Receptor/ERK Pathway.Sheng-Quan Hu et al.CNS neuroscience & therapeutics, 21(6), 520-529 (2015-04-29)
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Paired nanoinjection and electrophysiology assay to screen for bioactivity of compounds using the Drosophila melanogaster giant fiber system.Monica Mejia et al.Journal of visualized experiments : JoVE, (62)(62), doi:10-doi:10 (2012-04-25)
Confirming a Role for α9nAChRs and SK Potassium Channels in Type II Hair Cells of the Turtle Posterior Crista.Xiaorong Xu Parks et al.Frontiers in cellular neuroscience, 11, 356-356 (2017-12-05)
Differential modulation of GABAA and NMDA receptors by α7-nicotinic receptor desensitization in cultured rat hippocampal neurons.Lei Shen et al.Acta pharmacologica Sinica, 37(3), 312-321 (2016-01-26)
Perioperative activation of spinal α7 nAChR promotes recovery from preoperative stress-induced prolongation of postsurgical pain.Rao Sun et al.Brain, behavior, and immunity, 79, 294-308 (2019-02-24)
Neoatherosclerosis assessed with optical coherence tomography in restenotic bare metal and first- and second-generation drug-eluting stents.Lei Song et al.The international journal of cardiovascular imaging, 33(8), 1115-1124 (2017-03-11)
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The neuroprotective effects of SIRT1 in mice carrying the APP/PS1 double-transgenic mutation and in SH-SY5Y cells over-expressing human APP670/671 may involve elevated levels of α7 nicotinic acetylcholine receptors.Kun Cao et al.Aging, 12(2), 1792-1807 (2020-02-01)
Effects of preconditioning on the resistance to acute hypobaric hypoxia and their correction with selective antagonists of nicotinic receptors.E I Zakharova et al.Bulletin of experimental biology and medicine, 151(2), 179-182 (2012-01-13)
The α7 nicotinic acetylcholine receptor ligands methyllycaconitine, NS6740 and GTS-21 reduce lipopolysaccharide-induced TNF-α release from microglia.Morten S Thomsen et al.Journal of neuroimmunology, 251(1-2), 65-72 (2012-08-14)
The role of α7 nicotinic acetylcholine receptor in modulation of heart rate dynamics in endotoxemic rats.Roham Mazloom et al.PloS one, 8(12), e82251-e82251 (2013-12-18)
Lipid mediators in platelet concentrate and extracellular vesicles: Molecular mechanisms from membrane glycerophospholipids to bioactive molecules.Sami Valkonen et al.Biochimica et biophysica acta. Molecular and cell biology of lipids, 1864(8), 1168-1182 (2019-04-14)
Somatic integration of single ion channel responses of α7 nicotinic acetylcholine receptors enhanced by PNU-120596.Victor V Uteshev PloS one, 7(3), e32951-e32951 (2012-04-06)
Activation of Cholinergic Anti-Inflammatory Pathway in Peripheral Immune Cells Involved in Therapeutic Actions of α-Mangostin on Collagen-Induced Arthritis in Rats.Qin Yin et al.Drug design, development and therapy, 14, 1983-1993 (2020-06-18)
Intravaginal pressure profile of continent and incontinent women.Licia P Cacciari et al.Journal of biomechanics, 99, 109572-109572 (2020-01-15)
Nicotine enhances both excitatory and inhibitory synaptic inputs to inspiratory-activated airway vagal preganglionic neurons.Xujiao Zhou et al.Experimental physiology, 98(1), 67-80 (2012-07-04)
Immunophenotyping of a Stromal Vascular Fraction from Microfragmented Lipoaspirate Used in Osteoarthritis Cartilage Treatment and Its Lipoaspirate Counterpart.Denis Polancec et al.Genes, 10(6) (2019-06-27)
α7 Nicotinic receptor-mediated astrocytic gliotransmitter release: Aβ effects in a preclinical Alzheimer's mouse model.Tiina Maria Pirttimaki et al.PloS one, 8(11), e81828-e81828 (2013-12-07)
PHA-543613 preserves blood-brain barrier integrity after intracerebral hemorrhage in mice.Paul R Krafft et al.Stroke, 44(6), 1743-1747 (2013-04-25)
Nicotinic Acetylcholine Receptors Mediate the Suppressive Effect of an Injection of Diluted Bee Venom into the GV3 Acupoint on Oxaliplatin-Induced Neuropathic Cold Allodynia in Rats.Heera Yoon et al.Biological & pharmaceutical bulletin, 38(5), 710-714 (2015-03-11)
Antioxidant responses in cyanobacterium Microcystis aeruginosa caused by two commonly used UV filters, benzophenone-1 and benzophenone-3, at environmentally relevant concentrations.Feijian Mao et al.Journal of hazardous materials, 396, 122587-122587 (2020-04-27)
3D surface morphology imaging of opaque microstructures via light-field microscopy.Yong Da Sie et al.Scientific reports, 8(1), 10505-10505 (2018-07-14)
Hippocampal α7 nicotinic ACh receptors contribute to modulation of depression-like behaviour in C57BL/6J mice.Yann S Mineur et al.British journal of pharmacology, 175(11), 1903-1914 (2017-03-07)
Disparities in child mortality trends: what is the evidence from disadvantaged states in India? the case of Orissa and Madhya Pradesh.Kim-Huong Nguyen et al.International journal for equity in health, 12, 45-45 (2013-06-28)
Cotinine, a major nicotine metabolite, induces cell proliferation on urothelium in vitro and in vivo.Shugo Suzuki et al.Toxicology, 429, 152325-152325 (2019-11-05)
Blockade of nicotinic currents in hippocampal neurons defines methyllycaconitine as a potent and specific receptor antagonist.M Alkondon et al.Molecular pharmacology, 41(4), 802-808 (1992-04-01)
Allosteric modulation of nicotinic and GABARyan F Yoshimura et al.Neuropharmacology, 126, 38-47 (2017-08-27)
Galantamine Inhibits Aβ1-42-Induced Neurotoxicity by Enhancing α7nAChR Expression as a Cargo Carrier for LC3 Binding and Aβ1-42 Engulfment During Autophagic Degradation.Ming-Wei Lin et al.Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics, 17(2), 676-689 (2019-12-12)
Plaque Rupture in Coronary Atherosclerosis Is Associated With Increased Plaque Structural Stress.Charis Costopoulos et al.JACC. Cardiovascular imaging, 10(12), 1472-1483 (2017-07-25)
Wnt/β-catenin signaling plays an essential role in α7 nicotinic receptor-mediated neuroprotection of dopaminergic neurons in a mouse Parkinson's disease model.Yuan Liu et al.Biochemical pharmacology, 140, 115-123 (2017-05-30)
The nicotinic acetylcholine receptor-mediated reciprocal effects of the tobacco nitrosamine NNK and SLURP-1 on human mammary epithelial cells.Mina Kalantari-Dehaghi et al.International immunopharmacology, 29(1), 99-104 (2015-05-20)
Effect of plano-valgus foot posture on midfoot kinematics during barefoot walking in an adolescent population.Paolo Caravaggi et al.Journal of foot and ankle research, 11, 55-55 (2018-10-12)
Nicotine-induced enhancement of responding for conditioned reinforcement in rats: role of prior nicotine exposure and α4β2 nicotinic receptors.Elizabeth Glenn Guy et al.Psychopharmacology, 225(2), 429-440 (2012-08-14)
Stimulation of Retinal Pigment Epithelium With an α7 nAChR Agonist Leads to Müller Glia Dependent Neurogenesis in the Adult Mammalian Retina.Mark K Webster et al.Investigative ophthalmology & visual science, 60(2), 570-579 (2019-02-06)
Brain protection against ischemic stroke using choline as a new molecular bypass treatment.Xin Jin et al.Acta pharmacologica Sinica, 36(12), 1416-1425 (2015-11-17)
Prospective Randomized Comparison of Fractional Flow Reserve Versus Optical Coherence Tomography to Guide Revascularization of Intermediate Coronary Stenoses: One-Month Results.Antonio Maria Leone et al.Journal of the American Heart Association, 8(15), e012772-e012772 (2019-07-25)
Detailed optical modelling and light-management of thin-film organic solar cells with consideration of small-area effects.Benjamin Lipovšek et al.Optics express, 25(4), A176-A190 (2017-03-01)
Inhibition of alpha7 nicotinic receptors in the ventral hippocampus selectively attenuates reinstatement of morphine-conditioned place preference and associated changes in AMPA receptor binding.Victoria L Wright et al.Addiction biology, 24(4), 590-603 (2018-04-19)
Nicotinic receptor activation contrasts pathophysiological bursting and neurodegeneration evoked by glutamate uptake block on rat hypoglossal motoneurons.Silvia Corsini et al.The Journal of physiology, 594(22), 6777-6798 (2016-07-05)
Galantamine improves enhanced impulsivity, impairments of attention and long-term potentiation induced by prenatal nicotine exposure to mice.Takayoshi Mamiya et al.Biochemical pharmacology, 180, 114139-114139 (2020-07-12)
Alpha-7 nicotinic receptor allosteric modulator PNU120596 prevents lipopolysaccharide-induced anxiety, cognitive deficit and depression-like behaviors in mice.Sami Alzarea et al.Behavioural brain research, 366, 19-28 (2019-03-17)
Donepezil suppresses intracellular CaYoshinori Haraguchi et al.Journal of neuroinflammation, 14(1), 258-258 (2017-12-24)
Electroacupuncture attenuates learning and memory impairment via activation of α7nAChR-mediated anti-inflammatory activity in focal cerebral ischemia/reperfusion injured rats.Jiao Liu et al.Experimental and therapeutic medicine, 14(2), 939-946 (2017-08-16)
Activation of the alpha-7 nicotinic acetylcholine receptor (α7 nAchR) reverses referred mechanical hyperalgesia induced by colonic inflammation in mice.Robson Costa et al.Neuropharmacology, 63(5), 798-805 (2012-06-23)
Nicotine Evoked Currents in Human Primary Sensory Neurons.Xiulin Zhang et al.The journal of pain : official journal of the American Pain Society, 20(7), 810-818 (2019-01-20)
Effect of alpha-7 nicotinic acetylcholine receptor activation on beta-amyloid induced recognition memory impairment. Possible role of neurovascular function.Saeed Sadigh-Eteghad et al.Acta cirurgica brasileira, 30(11), 736-742 (2015-12-10)
Combined administration of SHP2 inhibitor SHP099 and the α7nAChR agonist PNU282987 protect mice against DSS‑induced colitis.Junhua Xiao et al.Molecular medicine reports, 22(3), 2235-2244 (2020-07-25)
Tunable microlens array fabricated by a silicone oil-induced swelled polydimethylsiloxane (PDMS) membrane bonded to a micro-milled microfluidic chip.Pin-Chuan Chen et al.Optics express, 28(20), 29815-29828 (2020-10-30)
Cholinergic Enhancement of Cell Proliferation in the Postnatal Neurogenic Niche of the Mammalian Spinal Cord.Laura F Corns et al.Stem cells (Dayton, Ohio), 33(9), 2864-2876 (2015-06-04)
Effect of α₇ nicotinic acetylcholine receptor agonists and antagonists on motor function in mice.Kevin D Welch et al.Toxicology and applied pharmacology, 266(3), 366-374 (2012-12-12)
Nicotinic receptors in the dorsal and ventral hippocampus differentially modulate contextual fear conditioning.Justin W Kenney et al.Hippocampus, 22(8), 1681-1690 (2012-01-25)
A behavioral economic analysis of the value-enhancing effects of nicotine and varenicline and the role of nicotinic acetylcholine receptors in male and female rats.Scott T Barrett et al.Behavioural pharmacology, 29(6), 493-502 (2018-04-11)
Voltage- and Temperature-Dependent Allosteric Modulation of α7 Nicotinic Receptors by PNU120596.Fabrio Sitzia et al.Frontiers in pharmacology, 2, 81-81 (2011-12-31)
[Nicotine effects on mitochondria membrane potential: participation of nicotinic acetylcholine receptors].G L Gergalova et al.Ukrains'kyi biokhimichnyi zhurnal (1999 ), 83(5), 13-21 (2012-01-27)
Alpha7 nicotinic acetylcholine receptor is required for blood-brain barrier injury-related CNS disorders caused by Cryptococcus neoformans and HIV-1 associated comorbidity factors.Bao Zhang et al.BMC infectious diseases, 15, 352-352 (2015-08-20)
Fractional Flow Reserve or Optical Coherence Tomography to Guide Management of Angiographically Intermediate Coronary Stenosis: A Single-Center Trial.Francesco Burzotta et al.JACC. Cardiovascular interventions, 13(1), 49-58 (2020-01-11)
Choline induces opposite changes in pyramidal neuron excitability and synaptic transmission through a nicotinic receptor-independent process in hippocampal slices.E Albiñana et al.Pflugers Archiv : European journal of physiology, 469(5-6), 779-795 (2017-02-09)
Recycling of iron and titanium resources from early tailings: From fundamental work to industrial application.Jihua Zhai et al.Chemosphere, 242, 125178-125178 (2019-11-02)
Modulation of the MAPKs pathways affects Aβ-induced cognitive deficits in Alzheimer's disease via activation of α7nAChR.Ke-Wei Chang et al.Neurobiology of learning and memory, 168, 107154-107154 (2020-01-07)
Activation of α7 nAChR by PNU-282987 improves synaptic and cognitive functions through restoring the expression of synaptic-associated proteins and the CaM-CaMKII-CREB signaling pathway.Xiao-Ling Wang et al.Aging, 12(1), 543-570 (2020-01-07)
Changes in Nicotinic Neurotransmission during Enteric Nervous System Development.Jaime Pei Pei Foong et al.The Journal of neuroscience : the official journal of the Society for Neuroscience, 35(18), 7106-7115 (2015-05-08)
Effects of acute and chronic nicotine on catecholamine neurons of the nucleus of the solitary tract.Stephen J Page et al.American journal of physiology. Regulatory, integrative and comparative physiology, 316(1), R38-R49 (2018-10-26)
Novel instrumented probe for measuring 3D pressure distribution along the vaginal canal.Licia P Cacciari et al.Journal of biomechanics, 58, 139-146 (2017-05-28)
Low molecular weight heparin for prevention of central venous catheter-related thrombosis in children.Marie-Claude Pelland-Marcotte et al.The Cochrane database of systematic reviews, 6, CD005982-CD005982 (2020-06-20)
Effects of age and sex on the single-dose pharmacokinetics and pharmacodynamics of apixaban.Charles E Frost et al.Clinical pharmacokinetics, 54(6), 651-662 (2015-01-13)
Pemphigus vulgaris antibodies target the mitochondrial nicotinic acetylcholine receptors that protect keratinocytes from apoptolysis.Alex Chernyavsky et al.International immunopharmacology, 29(1), 76-80 (2015-05-24)
Differential processing of thalamic information via distinct striatal interneuron circuits.Maxime Assous et al.Nature communications, 8, 15860-15860 (2017-06-13)
Nicotine exposure and the progression of chronic kidney disease: role of the α7-nicotinic acetylcholine receptor.Gabriel Rezonzew et al.American journal of physiology. Renal physiology, 303(2), F304-F312 (2012-05-04)
Activation of α7 nAChR by PNU-282987 improves synaptic and cognitive functions through restoring the expression of synaptic-associated proteins and the CaM-CaMKII-CREB signaling pathway.Xiao-Ling Wang et al.Aging, 12(1), 543-570 (2020-01-07)
Changes in Nicotinic Neurotransmission during Enteric Nervous System Development.Jaime Pei Pei Foong et al.The Journal of neuroscience : the official journal of the Society for Neuroscience, 35(18), 7106-7115 (2015-05-08)
Low molecular weight heparin for prevention of central venous catheter-related thrombosis in children.Marie-Claude Pelland-Marcotte et al.The Cochrane database of systematic reviews, 6, CD005982-CD005982 (2020-06-20)
A potentially novel nicotinic receptor in Aplysia neuroendocrine cells.Sean H White et al.Journal of neurophysiology, 112(2), 446-462 (2014-04-18)
Presynaptic α4β2 nicotinic acetylcholine receptors increase glutamate release and serotonin neuron excitability in the dorsal raphe nucleus.Julieta Garduño et al.The Journal of neuroscience : the official journal of the Society for Neuroscience, 32(43), 15148-15157 (2012-10-27)
Nicotinic Receptor Subunit Distribution in Auditory Cortex: Impact of Aging on Receptor Number and Function.Madan Ghimire et al.The Journal of neuroscience : the official journal of the Society for Neuroscience, 40(30), 5724-5739 (2020-06-17)
Effects of sazetidine-A, a selective α4β2* nicotinic receptor desensitizing agent, on body temperature regulation in mice and rats.Amir H Rezvani et al.European journal of pharmacology, 682(1-3), 110-117 (2012-03-06)
TRPV1 regulates excitatory innervation of OLM neurons in the hippocampus.Joaquin I Hurtado-Zavala et al.Nature communications, 8, 15878-15878 (2017-07-20)
Study on the Influence of Measuring AE Sensor Type on the Effectiveness of OLTC Defect Classification.Daria Wotzka et al.Sensors (Basel, Switzerland), 20(11) (2020-06-04)
Lipid mediators in platelet concentrate and extracellular vesicles: Molecular mechanisms from membrane glycerophospholipids to bioactive molecules.Sami Valkonen et al.Biochimica et biophysica acta. Molecular and cell biology of lipids, 1864(8), 1168-1182 (2019-04-14)
Plasticity of prefrontal attention circuitry: upregulated muscarinic excitability in response to decreased nicotinic signaling following deletion of α5 or β2 subunits.Michael K Tian et al.The Journal of neuroscience : the official journal of the Society for Neuroscience, 31(45), 16458-16463 (2011-11-11)
Somatic integration of single ion channel responses of α7 nicotinic acetylcholine receptors enhanced by PNU-120596.Victor V Uteshev PloS one, 7(3), e32951-e32951 (2012-04-06)
Activation of Cholinergic Anti-Inflammatory Pathway in Peripheral Immune Cells Involved in Therapeutic Actions of α-Mangostin on Collagen-Induced Arthritis in Rats.Qin Yin et al.Drug design, development and therapy, 14, 1983-1993 (2020-06-18)
Single particle tracking of alpha7 nicotinic AChR in hippocampal neurons reveals regulated confinement at glutamatergic and GABAergic perisynaptic sites.Thomas Bürli et al.PloS one, 5(7), e11507-e11507 (2010-07-17)
Acute Activation of α7-Nicotinic Receptors by Nicotine Improves Rodent Skin Flap Survival Through Nitrergic System.Ali Abbaszadeh-Kasbi et al.Annals of plastic surgery, 83(2), 211-216 (2019-03-08)
Activation of alpha7 acetylcholine receptors reduces neuropathic pain by decreasing dynorphin A release from microglia.Liu Ji et al.Brain research, 1715, 57-65 (2019-03-23)
Combination of NMR Methods To Reveal the Interfacial Structure of a Pharmaceutical Nanocrystal and Nanococrystal in the Suspended State.Taro Kojima et al.Molecular pharmaceutics, 15(9), 3901-3908 (2018-07-31)
Dual role of serotonin in the pathogenesis of indomethacin-induced small intestinal ulceration: pro-ulcerogenic action via 5-HT3 receptors and anti-ulcerogenic action via 5-HT4 receptors.Shinichi Kato et al.Pharmacological research, 66(3), 226-234 (2012-06-16)
Cognitive improvements in a mouse model with substituted 1,2,3-triazole agonists for nicotinic acetylcholine receptors.Kuntarat Arunrungvichian et al.ACS chemical neuroscience, 6(8), 1331-1340 (2015-05-16)
Plaque Characterization to Inform the Prediction and Prevention of Periprocedural Myocardial Infarction During Percutaneous Coronary Intervention: The CANARY Trial (Coronary Assessment by Near-infrared of Atherosclerotic Rupture-prone Yellow).Gregg W Stone et al.JACC. Cardiovascular interventions, 8(7), 927-936 (2015-05-25)
Membrane-dependent Activities of Human 15-LOX-2 and Its Murine Counterpart: IMPLICATIONS FOR MURINE MODELS OF ATHEROSCLEROSIS.Gunes Bender et al.The Journal of biological chemistry, 291(37), 19413-19424 (2016-07-21)
Activation of α7-nAChRs protects SH-SY5Y cells from 1-methyl-4-phenylpyridinium-induced apoptotic cell death via ERK/p53 signaling pathway.Shi Xu et al.Journal of cellular physiology, 234(10), 18480-18491 (2019-03-27)
α7-Nicotine acetylcholine receptor mediated nicotine induced cell survival and cisplatin resistance in oral cancer.Chia-Chen Hsu et al.Archives of oral biology, 111, 104653-104653 (2020-01-15)
Advanced characterization of IGCC slag by automated SEM-EDS analysis.Bokyeong Lee et al.Waste management (New York, N.Y.), 116, 140-146 (2020-08-18)
Genetic toxicity studies of glycolipids from Dacryopinax spathularia.Jens Bitzer et al.Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 123, 162-168 (2018-10-24)
Antinociception of the spirocyclopiperazinium salt compound LXM-15 via activating α7 nAChR and M4 mAChR and inhibiting CaMKIIα/cAMP/CREB/CGRP signalling pathway in mice.Hua Yang et al.Regulatory toxicology and pharmacology : RTP, 94, 108-114 (2018-01-22)
Cloning and Expression of Cockroach α7 Nicotinic Acetylcholine Receptor Subunit.Alison Cartereau et al.Frontiers in physiology, 11, 418-418 (2020-05-28)
The inimitable kynurenic acid: the roles of different ionotropic receptors in the action of kynurenic acid at a spinal level.Gabor Tuboly et al.Brain research bulletin, 112, 52-60 (2015-02-14)
Microarray analysis of juvenile hormone response in Drosophila melanogaster S2 cells.David K Willis et al.Journal of insect science (Online), 10, 66-66 (2010-08-03)
Cognitive improvements in a mouse model with substituted 1,2,3-triazole agonists for nicotinic acetylcholine receptors.Kuntarat Arunrungvichian et al.ACS chemical neuroscience, 6(8), 1331-1340 (2015-05-16)
α7-nAChR agonist enhances neural plasticity in the hippocampus via a GABAergic circuit.Matthew Townsend et al.Journal of neurophysiology, 116(6), 2663-2675 (2016-09-23)
The discriminative stimulus effects of epibatidine in C57BL/6J mice.Fernando B de Moura et al.Behavioural pharmacology, 31(6), 565-573 (2020-03-27)
Intravascular Ultrasound Assessment of In-Stent Restenosis in Saphenous Vein Grafts.Rafal Wolny et al.The American journal of cardiology, 123(7), 1052-1059 (2019-01-16)
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