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Structural insights into the dual substrate specificities of mammalian and Dictyostelium dihydropteridine reductases toward two stereoisomers of quinonoid dihydrobiopterin.Cong Chen et al.FEBS letters, 585(17), 2640-2646 (2011-08-09) Increasing dihydrobiopterin causes dysfunction of endothelial nitric oxide synthase in rats in vivo.Katsuhiko Noguchi et al.American journal of physiology. Heart and circulatory physiology, 301(3), H721-H729 (2011-05-31) Increased production of superoxide anion contributes to dysfunction of the arteriovenous fistula.Mykola V Tsapenko et al.American journal of physiology. 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Lung cellular and molecular physiology, 302(6), L616-L626 (2011-12-27) Emission properties of dihydropterins in aqueous solutions.Mariana P Serrano et al.Physical chemistry chemical physics : PCCP, 13(16), 7419-7425 (2011-03-17) Human endothelial dihydrofolate reductase low activity limits vascular tetrahydrobiopterin recycling.Jennifer Whitsett et al.Free radical biology & medicine, 63, 143-150 (2013-05-28) Accelerating Drug Discovery Efforts for Trypanosomatidic Infections Using an Integrated Transnational Academic Drug Discovery Platform.Carolina B Moraes et al.SLAS discovery : advancing life sciences R & D, 24(3), 346-361 (2019-02-21) Tetrahydrobiopterin is present in high quantity in human milk and has a vasorelaxing effect on newborn rat mesenteric arteries.Angela Weinmann et al.Pediatric research, 69(4), 325-329 (2010-12-24) Kinetics of acid-induced degradation of tetra- and dihydrobiopterin in relation to their relevance as biomarkers of endothelial function.Alan Mortensen et al.Biomarkers : biochemical indicators of exposure, response, and susceptibility to chemicals, 18(1), 55-62 (2012-10-17) Inhibition of nitric oxide synthase uncoupling by sepiapterin improves left ventricular function in streptozotocin-induced diabetic mice.Hiromi Jo et al.Clinical and experimental pharmacology & physiology, 38(8), 485-493 (2011-05-11) Characterization and reactivity of photodimers of dihydroneopterin and dihydrobiopterin.Mariana Vignoni et al.Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology, 11(6), 979-987 (2012-02-01) Endothelial nitric oxide synthase impairment is restored by clofibrate treatment in an animal model of hypertension.Luz Graciela Cervantes-Pérez et al.European journal of pharmacology, 685(1-3), 108-115 (2012-05-01) Cell type-specific recycling of tetrahydrobiopterin by dihydrofolate reductase explains differential effects of 7,8-dihydrobiopterin on endothelial nitric oxide synthase uncoupling.Kurt Schmidt et al.Biochemical pharmacology, 90(3), 246-253 (2014-05-28) Synthesis and recycling of tetrahydrobiopterin in endothelial function and vascular disease.Mark J Crabtree et al.Nitric oxide : biology and chemistry, 25(2), 81-88 (2011-05-10)

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