Spermine hydrochloride | CAS:306-67-2
Spermine hydrochloride
- 名称:精胺盐酸盐 | Spermine hydrochloride
- CAS号:306-67-2
- 别名:N1,N4-Bis(3-aminopropyl)-1,4-butanediamine hydrochloride; Spermine tetrahydrochloride
- 分子式:C10H26N4.4(HCl)
- 分子量:348.19
- EINESC号:206-189-8
产品描述
物理化学性质
熔点 | 310-311 ºC (dec.) |
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安全数据
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SDS
来源 | SDS样本 |
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没有数据 | 没有数据 |
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Over-expression of GAPDH in human colorectal carcinoma as a preferred target of 3-bromopyruvate propyl ester.Zhenjie Tang et al.Journal of bioenergetics and biomembranes, 44(1), 117-125 (2012-02-22)
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Aerosolized 3-bromopyruvate inhibits lung tumorigenesis without causing liver toxicity.Qi Zhang et al.Cancer prevention research (Philadelphia, Pa.), 5(5), 717-725 (2012-03-10)
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The extreme hyper-reactivity of Cys94 in lysozyme avoids its amorphous aggregation.Alessio Bocedi et al.Scientific reports, 8(1), 16050-16050 (2018-10-31)
Glutamine deprivation enhances antitumor activity of 3-bromopyruvate through the stabilization of monocarboxylate transporter-1.Simone Cardaci et al.Cancer research, 72(17), 4526-4536 (2012-07-10)
D-Amino acid oxidase-induced oxidative stress, 3-bromopyruvate and citrate inhibit angiogenesis, exhibiting potent anticancer effects.S M El Sayed et al.Journal of bioenergetics and biomembranes, 44(5), 513-523 (2012-07-18)
Human hepatocellular carcinoma in a mouse model: assessment of tumor response to percutaneous ablation by using glyceraldehyde-3-phosphate dehydrogenase antagonists.Shanmugasundaram Ganapathy-Kanniappan et al.Radiology, 262(3), 834-845 (2012-02-24)
Insights into the carboxyltransferase reaction of pyruvate carboxylase from the structures of bound product and intermediate analogs.Adam D Lietzan et al.Biochemical and biophysical research communications, 441(2), 377-382 (2013-10-26)
Enhancement of hexokinase II inhibitor-induced apoptosis in hepatocellular carcinoma cells via augmenting ER stress and anti-angiogenesis by protein disulfide isomerase inhibition.Su Jong Yu et al.Journal of bioenergetics and biomembranes, 44(1), 101-115 (2012-02-22)
3-Bromopyruvate alleviates the development of monocrotaline-induced rat pulmonary arterial hypertension by decreasing aerobic glycolysis, inducing apoptosis, and suppressing inflammation.Jie Liu et al.Chinese medical journal, 133(1), 49-60 (2020-01-11)
Blockade of N-Glycosylation Promotes Antitumor Immune Response of T Cells.Shigemi Sasawatari et al.Journal of immunology (Baltimore, Md. : 1950), 204(5), 1373-1385 (2020-01-24)
3-Bromopyruvate: a novel antifungal agent against the human pathogen Cryptococcus neoformans.Mariusz Dyląg et al.Biochemical and biophysical research communications, 434(2), 322-327 (2013-04-02)
Nitrogen Trapping as a Therapeutic Strategy in Tumors with Mitochondrial Dysfunction.Hanumantha Rao Madala et al.Cancer research, 80(17), 3492-3506 (2020-07-12)
Regulation of the proliferation of colon cancer cells by compounds that affect glycolysis, including 3-bromopyruvate, 2-deoxyglucose and biguanides.Michael A Lea et al.Anticancer research, 33(2), 401-407 (2013-02-09)
Inhibition of glucose turnover by 3-bromopyruvate counteracts pancreatic cancer stem cell features and sensitizes cells to gemcitabine.Orkhan Isayev et al.Oncotarget, 5(13), 5177-5189 (2014-07-13)
Regulation of death induction and chemosensitizing action of 3-bromopyruvate in myeloid leukemia cells: energy depletion, oxidative stress, and protein kinase activity modulation.Eva Calviño et al.The Journal of pharmacology and experimental therapeutics, 348(2), 324-335 (2013-12-07)
Fully automated continuous flow synthesis of highly functionalized imidazo[1,2-a] heterocycles.Ananda Herath et al.Organic letters, 12(3), 412-415 (2009-12-30)
Vitamin K2 promotes PI3K/AKT/HIF-1α-mediated glycolysis that leads to AMPK-dependent autophagic cell death in bladder cancer cells.Fengsen Duan et al.Scientific reports, 10(1), 7714-7714 (2020-05-10)
Science to practice: what do molecular biologic studies in rodent models add to our understanding of interventional oncologic procedures including percutaneous ablation by using glyceraldehyde-3-phosphate dehydrogenase antagonists?S Nahum Goldberg Radiology, 262(3), 737-739 (2012-02-24)
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Bromopyruvate mediates autophagy and cardiolipin degradation to monolyso-cardiolipin in GL15 glioblastoma cells.Magdalena Davidescu et al.Journal of bioenergetics and biomembranes, 44(1), 51-60 (2012-02-10)
Ultra-rapid glutathionylation of chymotrypsinogen in its molten globule-like conformation: A comparison to archaeal proteins.Alessio Bocedi et al.Scientific reports, 10(1), 8943-8943 (2020-06-04)
Experimental results using 3-bromopyruvate in mesothelioma: in vitro and in vivo studies.Philippe Icard et al.Journal of bioenergetics and biomembranes, 44(1), 81-90 (2012-02-11)
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3-Bromopyruvate inhibits calcium uptake by sarcoplasmic reticulum vesicles but not SERCA ATP hydrolysis activity.Douglas Jardim-Messeder et al.The international journal of biochemistry & cell biology, 44(5), 801-807 (2012-02-22)
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Glycolysis inhibitors as a potential therapeutic option to treat aggressive neuroblastoma expressing GLUT1.Kohei Matsushita et al.Journal of pediatric surgery, 47(7), 1323-1330 (2012-07-21)
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Peroxiredoxin 6 is the primary antioxidant enzyme for the maintenance of viability and DNA integrity in human spermatozoa.Maria C Fernandez et al.Human reproduction (Oxford, England) (2018-06-19)
MCT1-mediated transport of a toxic molecule is an effective strategy for targeting glycolytic tumors.Kivanç Birsoy et al.Nature genetics, 45(1), 104-108 (2012-12-04)
Repeated cisplatin treatment can lead to a multiresistant tumor cell population with stem cell features and sensitivity to 3-bromopyruvate.My Wintzell et al.Cancer biology & therapy, 13(14), 1454-1462 (2012-09-08)
Targeting aerobic glycolysis: 3-bromopyruvate as a promising anticancer drug.Simone Cardaci et al.Journal of bioenergetics and biomembranes, 44(1), 17-29 (2012-02-14)
3-Bromopyruvate (3BP) a fast acting, promising, powerful, specific, and effective "small molecule" anti-cancer agent taken from labside to bedside: introduction to a special issue.Peter L Pedersen Journal of bioenergetics and biomembranes, 44(1), 1-6 (2012-03-03)
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Products protected by valid patents are not offered for sale in countries where the sale of such products constitutes a patent infringement and its liability is at buyer's risk.
Products currently covered by valid US Patents are offered for R&D use in accordance with 35 USC 271 +A13(1).
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