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4-Hydroxy-4'-fluorobiphenyl | CAS:324-94-7
4-Hydroxy-4'-fluorobiphenyl
  • 名称:4-氟-4'-羟基联苯 | 4-Hydroxy-4'-fluorobiphenyl
  • CAS号:324-94-7
  • 别名:4-(4'-Fluorophenyl)phenol; 4'-Fluoro[1,1'-biphenyl]-4-ol
  • 分子式:C12H9FO
  • 分子量:188.20
  • EINESC号:

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物理化学性质

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Hydroxychavicol: a new phenolic antimutagen from betel leaf.A J Amonkar et al.Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 24(12), 1321-1324 (1986-12-01) Inhibition of TNF-α, and NF-κB and JNK pathways accounts for the prophylactic action of the natural phenolic, allylpyrocatechol against indomethacin gastropathy.Sudhir K Yadav et al.Biochimica et biophysica acta, 1830(6), 3776-3786 (2013-03-26) Hydroxychavicol: a potent xanthine oxidase inhibitor obtained from the leaves of betel, Piper betle.Kazuya Murata et al.Journal of natural medicines, 63(3), 355-359 (2009-04-24) Hydroxychavicol inhibits immune responses to mitigate cognitive dysfunction in rats.Anjali Pandey et al.Journal of neuroimmunology, 226(1-2), 48-58 (2010-07-08) Biochemical mechanism of healing activity of the natural phenolic, allylpyrocatechol against indomethacin-induced gastric ulceration in mice.Banerjee D Digestive Diseases and Sciences, 53(11), 2868-2877 (2008) Biotransformation and cytotoxic effects of hydroxychavicol, an intermediate of safrole metabolism, in isolated rat hepatocytes.Yoshio Nakagawa et al.Chemico-biological interactions, 180(1), 89-97 (2009-05-12) Piper betel leaf extract: anticancer benefits and bio-guided fractionation to identify active principles for prostate cancer management.Rutugandha Paranjpe et al.Carcinogenesis, 34(7), 1558-1566 (2013-02-23) Inducing the cell cycle arrest and apoptosis of oral KB carcinoma cells by hydroxychavicol: roles of glutathione and reactive oxygen species.M C Chang et al.British journal of pharmacology, 135(3), 619-630 (2002-02-09) Hydroxychavicol modulates benzo[a]pyrene-induced genotoxicity through induction of dihydrodiol dehydrogenase.Deh-Wei Tang et al.Toxicology letters, 152(3), 235-243 (2004-08-28) Protective effect of hydroxychavicol, a phenolic component of betel leaf, against the tobacco-specific carcinogens.A J Amonkar et al.Mutation research, 210(2), 249-253 (1989-02-01) Role of oxidative DNA damage in hydroxychavicol-induced genotoxicity.S F Lee-Chen et al.Mutagenesis, 11(5), 519-523 (1996-09-01) Elevated expression of cyclooxygenase (COX)-2 in oral squamous cell carcinoma--evidence for COX-2 induction by areca quid ingredients in oral keratinocytes.Deh-Wei Tang et al.Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology, 32(9), 522-529 (2003-09-13) Hydroxychavicol, a Piper betle leaf component, induces apoptosis of CML cells through mitochondrial reactive oxygen species-dependent JNK and endothelial nitric oxide synthase activation and overrides imatinib resistance.Jayashree B Chakraborty et al.Cancer science, 103(1), 88-99 (2011-09-29) Hydroxychavicol, a novel betel leaf component, inhibits platelet aggregation by suppression of cyclooxygenase, thromboxane production and calcium mobilization.M C Chang et al.British journal of pharmacology, 152(1), 73-82 (2007-07-21) Evaluation of the antimicrobial, antioxidant, and anti-inflammatory activities of hydroxychavicol for its potential use as an oral care agent.Sandeep Sharma et al.Antimicrobial agents and chemotherapy, 53(1), 216-222 (2008-06-25) In vitro antifungal activity of hydroxychavicol isolated from Piper betle L.Intzar Ali et al.Annals of clinical microbiology and antimicrobials, 9, 7-7 (2010-02-05) Hydroxychavicol: a new anti-nitrosating phenolic compound from betel leaf.M Nagabhushan et al.Mutagenesis, 4(3), 200-204 (1989-05-01) Reactive oxygen species are crucial for hydroxychavicol toxicity toward KB epithelial cells.J H Jeng et al.Cellular and molecular life sciences : CMLS, 61(1), 83-96 (2004-01-06) Enhanced hydroxychavicol-induced cytotoxic effects in glutathione-depleted HepG2 cells.C L Chen et al.Cancer letters, 155(1), 29-35 (2000-05-18) Modulation of Th1/Th2 cytokines and inflammatory mediators by hydroxychavicol in adjuvant induced arthritic tissues.Anjali Pandey et al.Cytokine, 49(1), 114-121 (2009-09-29) Transcriptome analysis reveals the molecular mechanisms of combined gamma-tocotrienol and hydroxychavicol in preventing the proliferation of 1321N1, SW1783, and LN18 glioma cancer cells.Amirah Abdul Rahman et al.Journal of physiology and biochemistry, 75(4), 499-517 (2019-08-16) TLC?bioautography-guided isolation, HPTLC and GC?MS-assisted analysis of bioactives of Piper betle leaf extract obtained from various extraction techniques: in vitro evaluation of phenolic content, antioxidant and antimicrobial activities.Annegowda, H. V., et al. Food Analytical Methods, 6.3, 715-726 (2013) Simultaneous estimation of hydroxychavicol and chlorogenic acid from Piper betel L. through RP-HPLC.Niladri Maity et al.Natural product research, 26(20), 1939-1941 (2011-09-20) A new hydroxychavicol dimer from the roots of Piper betle.Chwan-Fwu Lin et al.Molecules (Basel, Switzerland), 18(3), 2563-2570 (2013-02-28) Hydroxychavicol: A phytochemical targeting cutaneous fungal infections.Intzar Ali et al.Scientific reports, 6, 37867-37867 (2016-11-30) Identification of hydroxychavicol and its dimers, the lipase inhibitors contained in the Indonesian spice, Eugenia polyantha.Eisuke Kato et al.Food chemistry, 136(3-4), 1239-1242 (2012-12-01)
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