Difluoroacetonitrile | CAS:359-12-6
Difluoroacetonitrile
- 名称:二氟乙腈 | Difluoroacetonitrile
- CAS号:359-12-6
- 别名:2,2-Difluoroacetonitrile
- 分子式:C2HF2N
- 分子量:77.03
- EINESC号:
产品描述
物理化学性质
沸点 | 22.8-23.4 ºC** |
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闪点 | -46.3±23.2 ºC, 计算值* |
密度 | 1.1130 g/cm3 (14.5 ºC)** |
安全数据
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SDS
来源 | SDS样本 |
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没有数据 | 没有数据 |
产品合成路线
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Study of the cytotoxicity and particle action in human cancer cells of titanocene-functionalized materials with potential application against tumors.Alberto García-Peñas et al.Journal of inorganic biochemistry, 106(1), 100-110 (2011-11-25)
Titanocene difluorides with improved cytotoxic activity.Silvia Eger et al.Inorganic chemistry, 49(4), 1292-1294 (2010-01-09)
Water-soluble titanocene complexes with sulfur-containing amino acids: synthesis, spectroscopic, electrochemical and Ti(IV)-transferrin interaction studies.Yajaira Pérez et al.Journal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry, 10(2), 94-104 (2004-12-25)
Relationship between chemotherapy with paclitaxel, cisplatin, vinorelbine and titanocene dichloride and expression of proliferation markers and tumour suppressor gene p53 in human ovarian cancer xenografts in nude mice.H C Kolberg et al.European journal of gynaecological oncology, 26(4), 398-402 (2005-08-27)
Reconsideration of serum Ti(IV) transport: albumin and transferrin trafficking of Ti(IV) and its complexes.Arthur D Tinoco et al.Journal of the American Chemical Society, 130(7), 2262-2270 (2008-01-30)
Inclusion complexes of the antitumour metallocenes Cp(2)MCl(2) (M = Mo, Ti) with cucurbit[n]urils.Damian P Buck et al.Dalton transactions (Cambridge, England : 2003), (17)(17), 2328-2334 (2008-04-17)
Enhancement of the cytotoxicity of titanocene dichloride by aging in organic co-solvent.Mauro Ravera et al.Journal of inorganic biochemistry, 99(12), 2264-2269 (2005-10-08)
Stereospecific synthesis of highly functionalized tricyclic beta-lactams by radical cyclizations using titanocene monochloride.Gema Ruano et al.The Journal of organic chemistry, 67(23), 8243-8246 (2002-11-09)
Antitumor titanium compounds.Francesco Caruso et al.Mini reviews in medicinal chemistry, 4(1), 49-60 (2004-02-03)
Hyaluronic acid-drug conjugate modified core-shell MOFs as pH responsive nanoplatform for multimodal therapy of glioblastoma.Abhijeet Pandey et al.International journal of pharmaceutics, 588, 119735-119735 (2020-08-09)
A controlled release system of titanocene dichloride by electrospun fiber and its antitumor activity in vitro.Ping Chen et al.European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V, 76(3), 413-420 (2010-09-22)
Active cytotoxic reagents based on non-metallocene non-diketonato well-defined C2-symmetrical titanium complexes of tetradentate bis(phenolato) ligands.Michal Shavit et al.Journal of the American Chemical Society, 129(40), 12098-12099 (2007-09-20)
Evolved gas analysis of Ti(C5H5)2Cl2 by means of Li+ ion attachment mass spectrometry.Seiji Takahashi et al.The journal of physical chemistry. A, 116(2), 865-869 (2011-12-22)
Pharmaceutical formulation affects titanocene transferrin interactions.Katherine M Buettner et al.Dalton transactions (Cambridge, England : 2003), 40(37), 9580-9588 (2011-08-19)
Radical promoted Wagner-Meerwein-type rearrangement of epoxides in camphoric systems using a Ti(III) radical source.Samaresh Jana et al.The Journal of organic chemistry, 70(20), 8252-8254 (2005-11-10)
Structure-activity studies of Ti(IV) complexes: aqueous stability and cytotoxic properties in colon cancer HT-29 cells.Ramón Hernández et al.Journal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry, 13(5), 685-692 (2008-02-22)
Binding and hydrolysis studies of antitumoural titanocene dichloride and Titanocene Y with phosphate diesters.Andrea Erxleben et al.Journal of inorganic biochemistry, 104(4), 390-396 (2009-12-29)
Synthesis, Ti(IV) intake by apotransferrin and cytotoxic properties of functionalized titanocene dichlorides.Li Ming Gao et al.Journal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry, 12(7), 959-967 (2007-06-15)
Effects of titanocene dichloride derivatives on prostate cancer cells, specifically DNA damage-induced apoptosis.Sandra Cuffe et al.The Prostate, 71(2), 111-124 (2010-07-29)
The blood-testis barrier as a target of some chemotherapeutic agents.M L Pereira et al.Chemotherapy, 53(6), 446-448 (2007-10-25)
[Determination of organometallic antitumor crude drug titanocene dichloride by NP-HPLC].Yunlan Li et al.Se pu = Chinese journal of chromatography, 25(2), 282-283 (2007-06-22)
Tetrahedron Letters, 48, 3205-3205 (2007)
On the mechanism and kinetics of radical reactions of epoxyketones and epoxynitriles induced by titanocene chloride.A Fernandez-Mateos et al.The Journal of organic chemistry, 72(26), 9973-9982 (2007-11-30)
Titanium(IV) complexes: cytotoxicity and cellular uptake of titanium(IV) complexes on caco-2 cell line.Ramón Hernández et al.Toxicology in vitro : an international journal published in association with BIBRA, 24(1), 178-183 (2009-09-24)
The addition of a pregnenolone pendant group enhances the anticancer properties of titanocene dichloride in a mcf-7 xenograft model.Gladiany Ramos et al.Anticancer research, 34(4), 1609-1615 (2014-04-03)
Titanocene(III) chloride mediated radical induced allylation of aldimines: formal synthesis of C-linked 4'-deoxy aza-disaccharide.Sumit Saha et al.The Journal of organic chemistry, 76(17), 7229-7234 (2011-07-29)
A proposed mechanism for the inhibitory effect of the anticancer agent titanocene dichloride on tumour gelatinases and other proteolytic enzymes.Maria Pavlaki et al.Journal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry, 14(6), 947-957 (2009-04-25)
Enhancement of natural killer cell function by titanocenes in mice bearing Ehrlich ascites tumour.Marize C Valadares et al.European journal of pharmacology, 473(2-3), 191-196 (2003-08-02)
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