询 单
请 填 写 相 关 信 息
产品信息
产品名称
别名
CAS号
结构式 上传
联系方式
公司
联系人
电话
邮箱
内容
提交
中文版 English
请输入产品名称、CAS式、分子式
2,2,3,3-Tetrafluoro-3-(trifluoromethoxy)propanoic acid | CAS:377-73-1
2,2,3,3-Tetrafluoro-3-(trifluoromethoxy)propanoic acid
  • 名称:2,2,3,3-四氟-3-(三氟甲氧基)丙酸 | 2,2,3,3-Tetrafluoro-3-(trifluoromethoxy)propanoic acid
  • CAS号:377-73-1
  • 别名:
  • 分子式:C4HF7O3
  • 分子量:230.04
  • EINESC号:

产品描述

物理化学性质

沸点 126 ºC**
闪点 29.1±27.3 ºC, 计算值*
密度 1.718±0.06 g/cm3 (20 º
折射率 1.286 (589.3 nm 25 ºC)**

安全数据

没有数据没有数据

SDS

来源 SDS样本
没有数据没有数据
产品合成路线
更多

名称 CAS号
更多
文章
同行评议文献
Elevated COUP-TFII expression in dopaminergic neurons accelerates the progression of Parkinson's disease through mitochondrial dysfunction.Chung-Yang Kao et al.PLoS genetics, 16(6), e1008868-e1008868 (2020-06-25) Genome-wide microarray analysis identifies a potential role for striatal retrograde endocannabinoid signaling in the pathogenesis of experimental L-DOPA-induced dyskinesia.Yong Wang et al.Synapse (New York, N.Y.), 68(8), 332-343 (2014-03-07) Dopamine-dependent desensitization of dopaminergic signaling in the developing mouse striatum.Douglas S Kim et al.The Journal of neuroscience : the official journal of the Society for Neuroscience, 22(22), 9841-9849 (2002-11-13) Effects of repeated methyl levodopa administration on apomorphine sensitivity of rotational behavior and striatal Fos expression of rats with unilateral 6-OHDA lesions.K Kashihara et al.Neuroscience research, 38(3), 273-279 (2000-11-09) Intranasal administration of the dopaminergic agonists L-DOPA, amphetamine, and cocaine increases dopamine activity in the neostriatum: a microdialysis study in the rat.M A De Souza Silva et al.Journal of neurochemistry, 68(1), 233-239 (1997-01-01) L-dopa modulates motor cortex excitability in Alzheimer's disease patients.Alessandro Martorana et al.Journal of neural transmission (Vienna, Austria : 1996), 115(9), 1313-1319 (2008-07-03) Sodium tanshinone IIA silate increases melanin synthesis by activating the MAPK and PKA pathways and protects melanocytes from H2 O2-induced oxidative stressZhong H, et al. Royal Society of Chemistry Advances, 9(33), 18747-18757 (2019) L-dopa methyl ester attenuates amblyopia-induced neuronal injury in visual cortex of amblyopic cat.Rong Li et al.Gene, 527(1), 115-122 (2013-06-19) Melevodopa/carbidopa effervescent formulation in the treatment of motor fluctuations in advanced Parkinson's disease.Fabrizio Stocchi et al.Movement disorders : official journal of the Movement Disorder Society, 25(12), 1881-1887 (2010-07-30) 3-O-Methyldopa inhibits astrocyte-mediated dopaminergic neuroprotective effects of l-DOPAAsanuma M and Miyazaki I BMC Neuroscience, 17(1), 52-52 (2016) Pharmacokinetic evaluation of formulated levodopa methyl ester nasal delivery systems.Yeon Hong Lee et al.European journal of drug metabolism and pharmacokinetics, 39(4), 237-242 (2013-12-24) Effects of short- and long-acting dopamine agonists on sensitized dopaminergic neurotransmission in rats with unilateral 6-OHDA lesions.K Kashihara et al.Life sciences, 70(9), 1095-1100 (2002-02-28) Effects of l-dopa methyl ester on visual cortex injury induced by amblyopia and its underlying mechanism.Rong Li et al.Neuroscience letters, 508(2), 95-100 (2011-12-31) Clinical efficacy of a single afternoon dose of effervescent levodopa-carbidopa preparation (CHF 1512) in fluctuating Parkinson disease.Fabrizio Stocchi et al.Clinical neuropharmacology, 30(1), 18-24 (2007-02-03) The effects of central dopamine function of chronic L-DOPA (methyl ester hydrochloride) treatment of miceTabar J, et al. Pharmacology, Biochemistry, and Behavior, 33(1), 139-146 (1989) Determination, purity assessment and chiral separation of levodopa methyl ester in bulk and formulation pharmaceuticals.Jie Wang et al.Biomedical chromatography : BMC, 20(9), 904-910 (2006-01-04) Arachidonyl-2'-chloroethylamide (ACEA), a synthetic agonist of cannabinoid receptor, increases CB1R gene expression and reduces dyskinesias in a rat model of Parkinson's disease.Melissa Leija-Salazar et al.Pharmacology, biochemistry, and behavior, 194, 172950-172950 (2020-05-16) Daily motor performance after switching levodopa to melevodopa: an open-label on advanced Parkinson's disease with "delayed-on" and/or"wearing-off".D Bosco et al.Minerva medica, 102(2), 125-132 (2011-04-13) Striatal But Not Extrastriatal Dopamine Receptors Are Critical to Dopaminergic Motor Stimulation.Yuhan Wang et al.Frontiers in pharmacology, 8, 935-935 (2018-01-10) In vitro and in vivo antimycobacterial activity of an antihypertensive agent methyl-L-DOPA.Noton Kumar Dutta et al.In vivo (Athens, Greece), 19(3), 539-545 (2005-05-07) Nicotine alone and in combination with L-DOPA methyl ester or the D(2) agonist N-0923 in MPTP-induced chronic hemiparkinsonian monkeys.E F Domino et al.Experimental neurology, 158(2), 414-421 (1999-07-23) ALDH1A1 regulates postsynaptic μ-opioid receptor expression in dorsal striatal projection neurons and mitigates dyskinesia through transsynaptic retinoic acid signaling.Jing Pan et al.Scientific reports, 9(1), 3602-3602 (2019-03-07) Clinical efficacy of a single afternoon dose of effervescent levodopa-carbidopa preparation (CHF 1512) in fluctuating Parkinson disease.Fabrizio Stocchi et al.Clinical neuropharmacology, 30(1), 18-24 (2007-02-03) Opposite modulation of regulators of G protein signalling-2 RGS2 and RGS4 expression by dopamine receptors in the rat striatum.Muriel Geurts et al.Neuroscience letters, 333(2), 146-150 (2002-11-07) Increased excitability in serotonin neurons in the dorsal raphe nucleus in the 6-OHDA mouse model of Parkinson's disease.Alexander Prinz et al.Experimental neurology, 248, 236-245 (2013-07-03) Controlled-release levodopa methyl ester/benserazide-loaded nanoparticles ameliorate levodopa-induced dyskinesia in rats.Xinxin Yang et al.International journal of nanomedicine, 7, 2077-2086 (2012-05-24) Deep brain stimulation of the globus pallidus internus in the parkinsonian primate: local entrainment and suppression of low-frequency oscillations.Kevin W McCairn et al.Journal of neurophysiology, 101(4), 1941-1960 (2009-01-24) An L-dopaergic relay from the posterior hypothalamic nucleus to the rostral ventrolateral medulla and its cardiovascular function in anesthetized rats.M Nishihama et al.Neuroscience, 92(1), 123-135 (1999-07-07) Influence of layer position on in vitro and in vivo release of levodopa methyl ester and carbidopa from three-layer matrix tablets.R Bettini et al.European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V, 53(2), 227-232 (2002-03-07) 3-O-Methyldopa inhibits astrocyte-mediated dopaminergic neuroprotective effects of l-DOPAAsanuma M and Miyazaki I BMC Neuroscience, 17(1), 52-52 (2016) Pharmacokinetic evaluation of formulated levodopa methyl ester nasal delivery systems.Yeon Hong Lee et al.European journal of drug metabolism and pharmacokinetics, 39(4), 237-242 (2013-12-24) Elevated COUP-TFII expression in dopaminergic neurons accelerates the progression of Parkinson's disease through mitochondrial dysfunction.Chung-Yang Kao et al.PLoS genetics, 16(6), e1008868-e1008868 (2020-06-25) Effects of l-dopa methyl ester on visual cortex injury induced by amblyopia and its underlying mechanism.Rong Li et al.Neuroscience letters, 508(2), 95-100 (2011-12-31) L-Dopa methyl ester as a new antitumour agentWick MM Nature, 269(5628), 512-513 (1977) The effects of central dopamine function of chronic L-DOPA (methyl ester hydrochloride) treatment of miceTabar J, et al. Pharmacology, Biochemistry, and Behavior, 33(1), 139-146 (1989) Determination, purity assessment and chiral separation of levodopa methyl ester in bulk and formulation pharmaceuticals.Jie Wang et al.Biomedical chromatography : BMC, 20(9), 904-910 (2006-01-04) Arachidonyl-2'-chloroethylamide (ACEA), a synthetic agonist of cannabinoid receptor, increases CB1R gene expression and reduces dyskinesias in a rat model of Parkinson's disease.Melissa Leija-Salazar et al.Pharmacology, biochemistry, and behavior, 194, 172950-172950 (2020-05-16) Daily motor performance after switching levodopa to melevodopa: an open-label on advanced Parkinson's disease with "delayed-on" and/or"wearing-off".D Bosco et al.Minerva medica, 102(2), 125-132 (2011-04-13) Striatal But Not Extrastriatal Dopamine Receptors Are Critical to Dopaminergic Motor Stimulation.Yuhan Wang et al.Frontiers in pharmacology, 8, 935-935 (2018-01-10) In vitro and in vivo antimycobacterial activity of an antihypertensive agent methyl-L-DOPA.Noton Kumar Dutta et al.In vivo (Athens, Greece), 19(3), 539-545 (2005-05-07) Nicotine alone and in combination with L-DOPA methyl ester or the D(2) agonist N-0923 in MPTP-induced chronic hemiparkinsonian monkeys.E F Domino et al.Experimental neurology, 158(2), 414-421 (1999-07-23) ALDH1A1 regulates postsynaptic μ-opioid receptor expression in dorsal striatal projection neurons and mitigates dyskinesia through transsynaptic retinoic acid signaling.Jing Pan et al.Scientific reports, 9(1), 3602-3602 (2019-03-07) Intranasal administration of the dopaminergic agonists L-DOPA, amphetamine, and cocaine increases dopamine activity in the neostriatum: a microdialysis study in the ratDe Souza Silva MA, et al. Journal of Neurochemistry, 68(1), 233-239 (1997)
备注

Products protected by valid patents are not offered for sale in countries where the sale of such products constitutes a patent infringement and its liability is at buyer's risk.

Products currently covered by valid US Patents are offered for R&D use in accordance with 35 USC 271 +A13(1).

名称 CAS号

相关产品

相关资讯

热门标签
询 单
请 填 写 相 关 信 息
产品信息
产品名称
别名
CAS号
结构式 上传
联系方式
公司
联系人
电话
邮箱
内容
提交