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Light exposure at night disrupts host/cancer circadian regulatory dynamics: impact on the Warburg effect, lipid signaling and tumor growth prevention.David E Blask et al.PloS one, 9(8), e102776-e102776 (2014-08-08) Interaction of pituitary hormones and expression of clock genes modulated by bone morphogenetic protein-4 and melatonin.Naoko Tsukamoto-Yamauchi et al.Biochemical and biophysical research communications, 459(1), 172-177 (2015-03-03) Melatonin in Arabidopsis thaliana acts as plant growth regulator at low concentrations and preserves seed viability at high concentrations.Ismaél Gatica Hernández et al.Plant physiology and biochemistry : PPB, 94, 191-196 (2015-06-27) Potential impact of silymarin in combination with chlorogenic acid and/or melatonin in combating cardiomyopathy induced by carbon tetrachloride.Nouf M Al-Rasheed et al.Saudi journal of biological sciences, 21(3), 265-274 (2014-06-24) An interlaboratory comparison between similar methods for determination of melatonin, cortisol and testosterone in saliva.Marie A Jensen et al.Scandinavian journal of clinical and laboratory investigation, 74(5), 454-461 (2014-04-15) Synthesis, structure, theoretical and experimental in vitro antioxidant/pharmacological properties of α-aryl, N-alkyl nitrones, as potential agents for the treatment of cerebral ischemia.Abdelouahid Samadi et al.Bioorganic & medicinal chemistry, 19(2), 951-960 (2010-12-31) Diffused Intra-Oocyte Hydrogen Peroxide Activates Myeloperoxidase and Deteriorates Oocyte Quality.Sana N Khan et al.PloS one, 10(7), e0132388-e0132388 (2015-07-22) Identification of oxidative stress-related Xdh gene as a di(2-ethylhexyl)phthalate (DEHP) target and the use of melatonin to alleviate the DEHP-induced impairments in newborn mouse ovaries.Jing-Cai Liu et al.Journal of pineal research, 67(1), e12577-e12577 (2019-04-03) Ceramide metabolism regulates autophagy and apoptotic cell death induced by melatonin in liver cancer cells.Raquel Ordoñez et al.Journal of pineal research, 59(2), 178-189 (2015-05-16) Mobile phone radiation induces mode-dependent DNA damage in a mouse spermatocyte-derived cell line: a protective role of melatonin.Chuan Liu et al.International journal of radiation biology, 89(11), 993-1001 (2013-08-21) Melatonin mediates seasonal transitions in aggressive behavior and circulating androgen profiles in male Siberian hamsters.Kathleen M Munley et al.Hormones and behavior, 117, 104608-104608 (2019-11-02) Assessment of the relationship between melatonin, hormones of the pituitary-ovarian, -thyroid and -adrenocortical axes, and osteoprotegerin and its ligand sRANKL in girls with anorexia nervosa.Zofia Ostrowska et al.Postepy higieny i medycyny doswiadczalnej (Online), 67, 433-441 (2013-06-12) Melatonin reduces ulcerative colitis-associated local and systemic damage in mice: investigation on possible mechanisms.P P Trivedi et al.Digestive diseases and sciences, 58(12), 3460-3474 (2013-08-27) The pineal regulation of the immune system: 40 years since the discovery.György Csaba Acta microbiologica et immunologica Hungarica, 60(2), 77-91 (2013-07-06) Synthesis and in vitro evaluation of melatonin entrapped PLA nanoparticles: an oxidative stress and T-cell response using golden hamster.Sanjeev K Pandey et al.Journal of biomedical materials research. Part A, 103(9), 3034-3044 (2015-03-03) [Protective action of melatonin in experimental glaucoma in rats].I M Mykheĭtseva Fiziolohichnyi zhurnal (Kiev, Ukraine : 1994), 59(1), 78-83 (2013-05-30) Antioxidant activity of benzoxazolinonic and benzothiazolinonic derivatives in the LDL oxidation model.Ismaël Yekini et al.Bioorganic & medicinal chemistry, 17(22), 7823-7830 (2009-10-13) The protective effect of melatonin on neural stem cell against LPS-induced inflammation.Juhyun Song et al.BioMed research international, 2015, 854359-854359 (2015-02-24) Synthesis and in vivo anti-mutagenic activity of novel melatonin derivatives.Gamal A Elmegeed et al.European journal of medicinal chemistry, 43(4), 763-770 (2007-08-21) 1,6-Dihydro-2H-indeno[5,4-b]furan derivatives: design, synthesis, and pharmacological characterization of a novel class of highly potent MT₂-selective agonists.Tatsuki Koike et al.Journal of medicinal chemistry, 54(9), 3436-3444 (2011-04-09) Potent neuroprotective role of novel melatonin derivatives for management of central neuropathy induced by acrylamide in rats.Hanaa H Ahmed et al.European journal of medicinal chemistry, 45(11), 5452-5459 (2010-09-28) The effects of aminoguanidine, methylprednisolone, and melatonin on nerve recovery in peripheral facial nerve neurorrhaphy.Muhammed Yanilmaz et al.The Journal of craniofacial surgery, 26(3), 667-672 (2015-05-02) Nuclear redox imbalance affects circadian oscillation in HaCaT keratinocytes.Danilo Ranieri et al.The international journal of biochemistry & cell biology, 65, 113-124 (2015-06-02) Chemical genetics reveals a complex functional ground state of neural stem cells.Phedias Diamandis et al.Nature chemical biology, 3(5), 268-273 (2007-04-10) Effects of starvation, re-feeding and timing of food supply on daily rhythm features of gut melatonin in carp (Catla catla).Sourav Mukherjee et al.Chronobiology international, 32(9), 1264-1277 (2015-10-30) Co-expression of two subtypes of melatonin receptor on rat M1-type intrinsically photosensitive retinal ganglion cells.Wen-Long Sheng et al.PloS one, 10(2), e0117967-e0117967 (2015-02-26) Application of optimized dispersive liquid-liquid microextraction for determination of melatonin by HPLC-UV in plasma samples.M S Talebianpoor et al.Journal of chromatography. 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Subtype selective ligands based on beta-substituted N-acyl-5-methoxytryptamines and beta-substituted N-acyl-5-methoxy-1-methyltryptamines.Andrew Tsotinis et al.Journal of medicinal chemistry, 49(12), 3509-3519 (2006-06-09) [The activity of glutathione antioxidant system at melaksen and valdoxan action under experimental hyperthyroidism in rats].M V Gorbenko et al.Biomeditsinskaia khimiia, 59(5), 541-549 (2014-02-01) Contribution of nitric oxide-dependent guanylate cyclase and reactive oxygen species signaling pathways to desensitization of μ-opioid receptors in the rat locus coeruleus.Patricia Pablos et al.Neuropharmacology, 99, 422-431 (2015-08-10) (2-Benzyl-2,3,4,5-tetrahydro-1H-pyrido[4,3-b]indol-8-yl)-acetic acid: an aldose reductase inhibitor and antioxidant of zwitterionic nature.Milan Stefek et al.Bioorganic & medicinal chemistry, 19(23), 7181-7185 (2011-11-01) Melatonin receptors trigger cAMP production and inhibit chloride movements in nonpigmented ciliary epithelial cells.Fernando Huete-Toral et al.The Journal of pharmacology and experimental therapeutics, 352(1), 119-128 (2014-10-26) Melatonin prevents retinal oxidative stress and vascular changes in diabetic rats.G Ozdemir et al.Eye (London, England), 28(8), 1020-1027 (2014-06-14) Perioperative melatonin: not ready for prime time.L P H Andersen et al.British journal of anaesthesia, 112(1), 7-8 (2013-12-10) A predictive ligand-based Bayesian model for human drug-induced liver injury.Sean Ekins et al.Drug metabolism and disposition: the biological fate of chemicals, 38(12), 2302-2308 (2010-09-17) Cigarette smoke exposure impairs lipid metabolism by decreasing low-density lipoprotein receptor expression in hepatocytes.Baitao Ma et al.Lipids in health and disease, 19(1), 88-88 (2020-05-10) [Night shift work and prolactin as a breast cancer risk factor].Agnieszka Bukowska et al.Medycyna pracy, 64(2), 245-257 (2013-07-09) The circadian timing system and reproduction in mammals.B D Goldman Steroids, 64(9), 679-685 (1999-09-30) Angelman syndrome in adulthood.Anna M Larson et al.American journal of medical genetics. Part A, 167A(2), 331-344 (2014-11-28) Melatonin alleviates vascular calcification and ageing through exosomal miR-204/miR-211 cluster in a paracrine manner.Feng Xu et al.Journal of pineal research, 68(3), e12631-e12631 (2020-01-17) Circadian phase and its relationship to nighttime sleep in toddlers.Monique K LeBourgeois et al.Journal of biological rhythms, 28(5), 322-331 (2013-10-18) NADPH oxidase inhibitor, apocynin, improves renal glutathione status in Zucker diabetic fatty rats: a comparison with melatonin.Katarzyna Winiarska et al.Chemico-biological interactions, 218, 12-19 (2014-05-07) A novel quantitative structure-activity relationship method to predict the affinities of MT3 melatonin binding site.Hongying Du et al.European journal of medicinal chemistry, 43(12), 2861-2869 (2008-04-11) Development and validation of a high throughput direct radioimmunoassay for the quantitative determination of serum and plasma melatonin (N-acetyl-5-methoxytryptamine) in mice.André Welp et al.Journal of immunological methods, 358(1-2), 1-8 (2010-04-07) Melatonin regulation as a possible mechanism for probiotic (VSL#3) in irritable bowel syndrome: a randomized double-blinded placebo study.Reuben K Wong et al.Digestive diseases and sciences, 60(1), 186-194 (2014-08-06) The potential therapeutic effects of THC on Alzheimer's disease.Chuanhai Cao et al.Journal of Alzheimer's disease : JAD, 42(3), 973-984 (2014-07-16) [Universal therapeutic properties of melatonin].É B Arushanian Klinicheskaia meditsina, 91(2), 4-8 (2013-05-31) Melatonin acts through MT1/MT2 receptors to activate hypothalamic Akt and suppress hepatic gluconeogenesis in rats.Juliana A Faria et al.American journal of physiology. Endocrinology and metabolism, 305(2), E230-E242 (2013-05-23) Melatonin/polydopamine nanostructures for collective neuroprotection-based Parkinson's disease therapy.Anup K Srivastava et al.Biomaterials science, 8(5), 1345-1363 (2020-01-09) Clock-Controlled Regulation of the Acute Effects of Norepinephrine on Chick Pineal Melatonin Rhythms.Ye Li et al.Journal of biological rhythms, 30(6), 519-532 (2015-10-09) Melatonin administration alters nicotine preference consumption via signaling through high-affinity melatonin receptors.William J Horton et al.Psychopharmacology, 232(14), 2519-2530 (2015-02-24) GIRK Channels Mediate the Nonphotic Effects of Exogenous Melatonin.Lauren M Hablitz et al.The Journal of neuroscience : the official journal of the Society for Neuroscience, 35(45), 14957-14965 (2015-11-13) 1,6-Dihydro-2H-indeno[5,4-b]furan derivatives: design, synthesis, and pharmacological characterization of a novel class of highly potent MT₂-selective agonists.Tatsuki Koike et al.Journal of medicinal chemistry, 54(9), 3436-3444 (2011-04-09) Contribution of nitric oxide-dependent guanylate cyclase and reactive oxygen species signaling pathways to desensitization of μ-opioid receptors in the rat locus coeruleus.Patricia Pablos et al.Neuropharmacology, 99, 422-431 (2015-08-10) Effects of melatonin on nervous system aging: neurogenesis and neurodegeneration.Golmaryam Sarlak et al.Journal of pharmacological sciences, 123(1), 9-24 (2013-08-30) [The activity of glutathione antioxidant system at melaksen and valdoxan action under experimental hyperthyroidism in rats].M V Gorbenko et al.Biomeditsinskaia khimiia, 59(5), 541-549 (2014-02-01) Melatonin ameliorates the advanced maternal age-associated meiotic defects in oocytes through the SIRT2-dependent H4K16 deacetylation pathway.Congyang Li et al.Aging, 12(2), 1610-1623 (2020-01-26) Mapping the melatonin receptor. 7. Subtype selective ligands based on beta-substituted N-acyl-5-methoxytryptamines and beta-substituted N-acyl-5-methoxy-1-methyltryptamines.Andrew Tsotinis et al.Journal of medicinal chemistry, 49(12), 3509-3519 (2006-06-09) [Night shift work and prolactin as a breast cancer risk factor].Agnieszka Bukowska et al.Medycyna pracy, 64(2), 245-257 (2013-07-09) Synthesis and characterization of novel indole derivatives reveal improved therapeutic agents for treatment of ischemia/reperfusion (I/R) injury.Wei Bi et al.Journal of medicinal chemistry, 53(18), 6763-6767 (2010-08-25) Advances in the research of melatonin in autism spectrum disorders: literature review and new perspectives.Sylvie Tordjman et al.International journal of molecular sciences, 14(10), 20508-20542 (2013-10-17) Melatonin regulates the autophagic flux via activation of alpha-7 nicotinic acetylcholine receptors.Jae-Kyo Jeong et al.Journal of pineal research, 59(1), 24-37 (2015-03-27) Melatonin induces apoptosis of colorectal cancer cells through HDAC4 nuclear import mediated by CaMKII inactivation.Jia-Yi Wei et al.Journal of pineal research, 58(4), 429-438 (2015-03-11) (2-Benzyl-2,3,4,5-tetrahydro-1H-pyrido[4,3-b]indol-8-yl)-acetic acid: an aldose reductase inhibitor and antioxidant of zwitterionic nature.Milan Stefek et al.Bioorganic & medicinal chemistry, 19(23), 7181-7185 (2011-11-01) Melatonin receptors trigger cAMP production and inhibit chloride movements in nonpigmented ciliary epithelial cells.Fernando Huete-Toral et al.The Journal of pharmacology and experimental therapeutics, 352(1), 119-128 (2014-10-26) Melatonin prevents retinal oxidative stress and vascular changes in diabetic rats.G Ozdemir et al.Eye (London, England), 28(8), 1020-1027 (2014-06-14) Cigarette smoke exposure impairs lipid metabolism by decreasing low-density lipoprotein receptor expression in hepatocytes.Baitao Ma et al.Lipids in health and disease, 19(1), 88-88 (2020-05-10) Melatonin: Quantum-chemical and biochemical investigation of antioxidant activity.Zhivko A Velkov et al.European journal of medicinal chemistry, 44(7), 2834-2839 (2009-01-27) Angelman syndrome in adulthood.Anna M Larson et al.American journal of medical genetics. Part A, 167A(2), 331-344 (2014-11-28) The circadian timing system and reproduction in mammals.B D Goldman Steroids, 64(9), 679-685 (1999-09-30) Synthesis, inhibitory activity of cholinesterases, and neuroprotective profile of novel 1,8-naphthyridine derivatives.Cristóbal de Los Ríos et al.Journal of medicinal chemistry, 53(14), 5129-5143 (2010-06-26) Perioperative melatonin: not ready for prime time.L P H Andersen et al.British journal of anaesthesia, 112(1), 7-8 (2013-12-10) A predictive ligand-based Bayesian model for human drug-induced liver injury.Sean Ekins et al.Drug metabolism and disposition: the biological fate of chemicals, 38(12), 2302-2308 (2010-09-17) Melatonin is protective against 6-hydroxydopamine-induced oxidative stress in a hemiparkinsonian rat model.O Ozsoy et al.Free radical research, 49(8), 1004-1014 (2015-03-21) Melatonin alleviates meiotic defects in fetal mouse oocytes induced by Di (2-ethylhexyl) phthalate in vitro.Zhong-Yi Sun et al.Aging, 10(12), 4175-4187 (2018-12-29) Melatonin alleviates the deterioration of oocytes from mice subjected to repeated superovulation.Peng Xiao et al.Journal of cellular physiology, 234(8), 13413-13422 (2019-01-05) Pharmacological characterization of a highly selective and potent partial agonist of the MT₂ melatonin receptor.Taku Sakurai et al.Pharmacology, 93(5-6), 244-252 (2014-07-26) Effects of caffeine on the human circadian clock in vivo and in vitro.Tina M Burke et al.Science translational medicine, 7(305), 305ra146-305ra146 (2015-09-18) Melatonin potentiates the anti-tumour effect of pravastatin in rat mammary gland carcinoma model.Peter Orendáš et al.International journal of experimental pathology, 95(6), 401-410 (2014-10-02) Melatonin administration alters nicotine preference consumption via signaling through high-affinity melatonin receptors.William J Horton et al.Psychopharmacology, 232(14), 2519-2530 (2015-02-24) Poricoic acid A enhances melatonin inhibition of AKI-to-CKD transition by regulating Gas6/AxlNFκB/Nrf2 axis.Dan-Qian Chen et al.Free radical biology & medicine, 134, 484-497 (2019-02-05) Pharmacological characterization of a highly selective and potent partial agonist of the MT₂ melatonin receptor.Taku Sakurai et al.Pharmacology, 93(5-6), 244-252 (2014-07-26) Melatonin blunts the mitochondrial/NLRP3 connection and protects against radiation-induced oral mucositis.Francisco Ortiz et al.Journal of pineal research, 58(1), 34-49 (2014-11-13) A combined effect of dextromethorphan and melatonin on neuropathic pain behavior in rats.Shuxing Wang et al.Brain research, 1288, 42-49 (2009-07-15) Decreased melatonin secretion is associated with increased intestinal permeability and marker of endotoxemia in alcoholics.Garth R Swanson et al.American journal of physiology. 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course of expression of the Nox family in the brain in a rat experimental cerebral ischemia and reperfusion model: effects of melatonin.Haiying Li et al.Journal of pineal research, 57(1), 110-119 (2014-05-29) Melatonin/polydopamine nanostructures for collective neuroprotection-based Parkinson's disease therapy.Anup K Srivastava et al.Biomaterials science, 8(5), 1345-1363 (2020-01-09) Clock-Controlled Regulation of the Acute Effects of Norepinephrine on Chick Pineal Melatonin Rhythms.Ye Li et al.Journal of biological rhythms, 30(6), 519-532 (2015-10-09) Doxorubicin resistance in breast cancer is driven by light at night-induced disruption of the circadian melatonin signal.Shulin Xiang et al.Journal of pineal research, 59(1), 60-69 (2015-04-11) Developing structure-activity relationships for the prediction of hepatotoxicity.Nigel Greene et al.Chemical research in toxicology, 23(7), 1215-1222 (2010-06-18) Mitigation of Radiation-Induced Lung Pneumonitis and Fibrosis Using Metformin and Melatonin: A Histopathological Study.Bagher Farhood et al.Medicina (Kaunas, Lithuania), 55(8) (2019-08-02) Inhibition of VEGF expression through blockade of Hif1α and STAT3 signalling mediates the anti-angiogenic effect of melatonin in HepG2 liver cancer cells.S Carbajo-Pescador et al.British journal of cancer, 109(1), 83-91 (2013-06-13) Melatonin analgesia is associated with improvement of the descending endogenous pain-modulating system in fibromyalgia: a phase II, randomized, double-dummy, controlled trial.Simone Azevedo de Zanette et al.BMC pharmacology & toxicology, 15, 40-40 (2014-07-24) Melatonin supplementation during controlled ovarian stimulation for women undergoing assisted reproductive technology: systematic review and meta-analysis of randomized controlled trials.Ludimila M D Seko et al.Fertility and sterility, 101(1), 154-161 (2013-11-05) Melatonin Orchestrates Lipid Homeostasis through the Hepatointestinal Circadian Clock and Microbiota during Constant Light 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Federation of American Societies for Experimental Biology, 13(14), 1930-1938 (1999-11-02) Melatonin attenuates hypoxic pulmonary hypertension by inhibiting the inflammation and the proliferation of pulmonary arterial smooth muscle cells.Haifeng Jin et al.Journal of pineal research, 57(4), 442-450 (2014-09-25) Melatonin: a hormone, a tissue factor, an autocoid, a paracoid, and an antioxidant vitamin.Tan DX Journal of Pineal Research, 34(1), 75-78 (2003) Extracellular matrix modulates the biological effects of melatonin in mesenchymal stem cells.Fan He et al.The Journal of endocrinology, 223(2), 167-180 (2014-09-12) Melatonin prevents cell death and mitochondrial dysfunction via a SIRT1-dependent mechanism during ischemic-stroke in mice.Yang Yang et al.Journal of pineal research, 58(1), 61-70 (2014-11-18) The Circadian System Contributes to Apnea Lengthening across the Night in Obstructive Sleep Apnea.Matthew P Butler et al.Sleep, 38(11), 1793-1801 (2015-06-04) Melatonin improves 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