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5-Bromo-2,4-difluoroaniline | CAS:452-92-6
5-Bromo-2,4-difluoroaniline
  • 名称:5-溴-2,4-二氟苯胺 | 5-Bromo-2,4-difluoroaniline
  • CAS号:452-92-6
  • 别名:2,4-Difluoro-5-bromoaniline
  • 分子式:C6H4BrF2N
  • 分子量:208.00
  • EINESC号:

产品描述

物理化学性质

熔点 25-26 ºC
沸点 223 ºC
闪点 89 ºC
密度 1.788

安全数据

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SDS

来源 SDS样本
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Karayannis Analytica Chimica Acta, 442.2, 231-239 (2001) [Effects of garlic oil on 2, 5-HD induced lipid peroxidation damage in rat nerve tissues].Xu-Cong Gao et al.Zhonghua lao dong wei sheng zhi ye bing za zhi = Zhonghua laodong weisheng zhiyebing zazhi = Chinese journal of industrial hygiene and occupational diseases, 26(11), 649-653 (2009-05-27) [Effects of garlic oil on n-hexane metabolized to 2, 5-hexanedione in mice serum].Xu-cong Gao et al.Zhonghua lao dong wei sheng zhi ye bing za zhi = Zhonghua laodong weisheng zhiyebing zazhi = Chinese journal of industrial hygiene and occupational diseases, 27(5), 262-265 (2009-06-23) [The effect of 2,5-hexanedione on nerve growth factor in sciatic nerve of rats and VSC4.1 cell].Qing-Jun Liu et al.Zhonghua yu fang yi xue za zhi [Chinese journal of preventive medicine], 44(1), 18-23 (2010-04-15) Fate of germ cells in 2,5-hexanedione-induced testicular injury. II. Atrophy persists due to a reduced stem cell mass and ongoing apoptosis.E K Allard et al.Toxicology and applied pharmacology, 137(2), 149-156 (1996-04-01) Highly efficient and stereoselective biosynthesis of (2S,5S)-hexanediol with a dehydrogenase from Saccharomyces cerevisiae.Marion Müller et al.Organic & biomolecular chemistry, 8(7), 1540-1550 (2010-03-20) Neurotoxic effect of 2,5-hexanedione on neural progenitor cells and hippocampal neurogenesis.Min-Sun Kim et al.Toxicology, 260(1-3), 97-103 (2009-05-26) The effect of 2,5-hexanedione on myelin protein zero expression, and its mitigation using Ginkgo biloba extract.Lei Zhao et al.Biomedical and environmental sciences : BES, 24(4), 374-382 (2011-11-24) Alternative biomarkers of n-hexane exposure: characterization of aminoderived pyrroles and thiol-pyrrole conjugates in urine of rats exposed to 2,5-hexanedione.M Edite Torres et al.Toxicology letters, 224(1), 54-63 (2014-01-25) New insights into mechanisms of gamma-diketone-induced axonopathy.Desire Tshala-Katumbay et al.Neurochemical research, 34(11), 1919-1923 (2009-05-01) Suppression of radiation-induced testicular germ cell apoptosis by 2,5-hexanedione pretreatment. I. Histopathological analysis reveals stage dependence of attenuated apoptosis.Hideki Yamasaki et al.Toxicological sciences : an official journal of the Society of Toxicology, 117(2), 449-456 (2010-07-10) The effect of 2,5-hexanedione on permeability of blood-nerve barrier in rats.Qingjun Liu et al.Human & experimental toxicology, 29(6), 497-506 (2010-01-07) 2,5-Hexanedione induces human ovarian granulosa cell apoptosis through BCL-2, BAX, and CASPASE-3 signaling pathways.Yan Sun et al.Archives of toxicology, 86(2), 205-215 (2011-09-09) Toxicity and metabolism of the neurotoxic hexacarbons n-hexane, 2-hexanone, and 2,5-hexanedione.D Couri et al.Annual review of pharmacology and toxicology, 22, 145-166 (1982-01-01) Suppression of radiation-induced testicular germ cell apoptosis by 2,5-hexanedione pretreatment. II. Gene array analysis reveals adaptive changes in cell cycle and cell death pathways.Sarah N Campion et al.Toxicological sciences : an official journal of the Society of Toxicology, 117(2), 457-465 (2010-07-10) Molecular alterations underlying the enhanced disruption of spermatogenesis by 2,5-hexanedione and carbendazim co-exposure.Sarah N Campion et al.Reproductive toxicology (Elmsford, N.Y.), 33(3), 382-389 (2012-03-03) Experimental neuropathy produced by 2,5-hexanedione--a major metabolite of the neurotoxic industrial solvent methyl n-butyl ketone.P S Spencer et al.Journal of neurology, neurosurgery, and psychiatry, 38(8), 771-775 (1975-08-01) Escherichia coli kduD encodes an oxidoreductase that converts both sugar and steroid substrates.Agne Tubeleviciute et al.Applied microbiology and biotechnology, 98(12), 5471-5485 (2014-02-11) Sperm mRNA transcripts are indicators of sub-chronic low dose testicular injury in the Fischer 344 rat.Sara E Pacheco et al.PloS one, 7(8), e44280-e44280 (2012-09-07) An improved synthesis of (-)-(2R, 5R)-2, 5-dimethylpyrrolidine.Short RP, et al. The Journal of Organic Chemistry, 54(7), 1755-1756 (1989) The effect of 3,4-dimethyl substitution on the neurotoxicity of 2,5-hexanedione. II. Dimethyl substitution accelerates pyrrole formation and protein crosslinking.D C Anthony et al.Toxicology and applied pharmacology, 71(3), 372-382 (1983-12-01) Suppression of radiation-induced testicular germ cell apoptosis by 2,5-hexanedione pretreatment. III. Candidate gene analysis identifies a role for fas in the attenuation of X-ray-induced apoptosis.Sarah N Campion et al.Toxicological sciences : an official journal of the Society of Toxicology, 117(2), 466-474 (2010-07-10) Comparative covalent protein binding of 2,5-hexanedione and 3-acetyl-2,5-hexanedione in the rat.Anthony P DeCaprio et al.Journal of toxicology and environmental health. Part A, 72(14), 861-869 (2009-06-27) The background of mitochondrial DNA haplogroup J increases the sensitivity of Leber's hereditary optic neuropathy cells to 2,5-hexanedione toxicity.Anna Ghelli et al.PloS one, 4(11), e7922-e7922 (2009-11-26) [Effect of 2,5-hexanedione on myelin protein zero in sciatic nerve and its antibody in serum of rats at different time points].Qingjun Liu et al.Wei sheng yan jiu = Journal of hygiene research, 39(3), 275-278 (2010-06-24) 2,5-hexanedione altered the degradation of low-molecular-weight neurofilament in rat nerve tissues.Fuyong Song et al.Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 50(12), 4277-4284 (2012-09-13) Communication: stabilization of radical anions with weakly bound electron in condensed media: a case study of diacetonyl radical anion.Elizaveta V Saenko et al.The Journal of chemical physics, 135(10), 101103-101103 (2011-09-22) Exposure to 2,5-hexanedione can induce neural malformations in chick embryos.Xin Cheng et al.Neurotoxicology, 33(5), 1239-1247 (2012-07-31) Optimization of a filter-lysis protocol to purify rat testicular homogenates for automated spermatid counting.Sara E Pacheco et al.Journal of andrology, 33(5), 811-816 (2012-01-14) [Effects of garlic oil, age and sex on n-hexane metabolism in rats].Jie Yan et al.Zhonghua lao dong wei sheng zhi ye bing za zhi = Zhonghua laodong weisheng zhiyebing zazhi = Chinese journal of industrial hygiene and occupational diseases, 29(1), 49-52 (2011-05-31) 2,5-hexanedione-induced testicular injury.Kim Boekelheide et al.Annual review of pharmacology and toxicology, 43, 125-147 (2002-12-10) The effect of workload on biological monitoring of occupational exposure to toluene and n-Hexane: contribution of physiologically based toxicokinetic modeling.Irène Sari-Minodier et al.Journal of occupational and environmental hygiene, 6(7), 415-432 (2009-04-23) Role of N-acetylcysteine in protecting against 2,5-hexanedione neurotoxicity in a rat model: changes in urinary pyrroles levels and motor activity performance.M Edite Torres et al.Environmental toxicology and pharmacology, 38(3), 807-813 (2014-10-13) [Effect of 2,5-hexanedione on light-molecular-weight neurofilaments (NF-L) degradation of rat nerve tissues].Chao-shuang Zou et al.Zhonghua lao dong wei sheng zhi ye bing za zhi = Zhonghua laodong weisheng zhiyebing zazhi = Chinese journal of industrial hygiene and occupational diseases, 30(6), 418-422 (2012-08-31) Determination of 2,5-hexanedione in urine by headspace solid-phase microextraction and gas chromatography.Antônio Felipe F Oliveira et al.Journal of analytical toxicology, 33(4), 223-228 (2009-05-28)
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