沸点	158 ºC (743 mmHg)
闪点	43 ºC
密度	1.104
折射率	1.4876-1.4896

危险类别码	R10
安全说明书	S16

来源	SDS样本
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L-ergothioneine modulates oxidative damage in the kidney and liver of rats in vivo: studies upon the profile of polyunsaturated fatty acids.Monica Deiana et al.Clinical nutrition (Edinburgh, Scotland), 23(2), 183-193 (2004-03-20) Rat Kidney Slices for Evaluation of Apical Membrane Transporters in Proximal Tubular Cells.Hiroshi Arakawa et al.Journal of pharmaceutical sciences, 108(8), 2798-2804 (2019-04-09) Functional genomics of novel secondary metabolites from diverse cyanobacteria using untargeted metabolomics.Richard Baran et al.Marine drugs, 11(10), 3617-3631 (2013-10-03) Co-Expression Networks for Causal Gene Identification Based on RNA-Seq Data of Corynebacterium pseudotuberculosis.Edian F Franco et al.Genes, 11(7) (2020-07-18) The functional interplay of low molecular weight thiols in Mycobacterium tuberculosis.C Sao Emani et al.Journal of biomedical science, 25(1), 55-55 (2018-07-13) Water-Soluble Polysaccharide Extracts from the Oyster Culinary-Medicinal Mushroom Pleurotus ostreatus (Agaricomycetes) with HMGCR Inhibitory Activity.Alicia Gil-Ramirez et al.International journal of medicinal mushrooms, 19(10), 879-892 (2017-12-20) Administration of Pure Ergothioneine to Healthy Human Subjects: Uptake, Metabolism, and Effects on Biomarkers of Oxidative Damage and Inflammation.Irwin K Cheah et al.Antioxidants & redox signaling, 26(5), 193-206 (2016-08-05) Preparation of culinary-medicinal king oyster mushroom Pleurotus eryngii-fermented products with high ergothioneine content and their taste quality.Shih-Yu Chen et al.International journal of medicinal mushrooms, 14(1), 85-93 (2012-02-22) Substantial fibrin amyloidogenesis in type 2 diabetes assessed using amyloid-selective fluorescent stainsPretorius E, et al. Cardiovascular Diabetology, 16(1), 141-141 (2017) Comprehensive Examination of the Mouse Lung Metabolome Following Mycobacterium tuberculosis Infection Using a Multiplatform Mass Spectrometry Approach.Miguel Fernández-García et al.Journal of proteome research, 19(5), 2053-2070 (2020-04-15) The biology of ergothioneine, an antioxidant nutraceutical.Irina Borodina et al.Nutrition research reviews, 33(2), 190-217 (2020-02-14) Gut-Resident Lactobacilli Activate Hepatic Nrf2 and Protect Against Oxidative Liver Injury.Bejan J Saeedi et al.Cell metabolism, 31(5), 956-968 (2020-03-28) Effect of ergothioneine on acute lung injury and inflammation in cytokine insufflated rats.John E Repine et al.Preventive medicine, 54 Suppl, S79-S82 (2011-12-27) Ergothioneine protects against neuronal injury induced by β-amyloid in mice.Nae-Cherng Yang et al.Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 50(11), 3902-3911 (2012-08-28) Darcy C Engelhart et al.International journal of molecular sciences, 21(6) (2020-03-19)The SLC22 family of transporters is widely expressed, evolutionarily conserved, and plays a major role in regulating homeostasis by transporting small organic molecules such as metabolites, signaling molecules, and antioxidants. Analysis of transporters in fruit flies provides a simple yet... SAR11 bacteria have a high affinity and multifunctional glycine betaine transporter.Stephen E Noell et al.Environmental microbiology, 21(7), 2559-2575 (2019-05-16) Redox and Thiols in Archaea.Mamta Rawat et al.Antioxidants (Basel, Switzerland), 9(5) (2020-05-10) Xu, J. and Yadan, J.C. The Journal of Organic Chemistry, 60, 6296-6296 (1995) Gut-Resident Lactobacilli Activate Hepatic Nrf2 and Protect Against Oxidative Liver Injury.Bejan J Saeedi et al.Cell metabolism, 31(5), 956-968 (2020-03-28) Water-Soluble Polysaccharide Extracts from the Oyster Culinary-Medicinal Mushroom Pleurotus ostreatus (Agaricomycetes) with HMGCR Inhibitory Activity.Alicia Gil-Ramirez et al.International journal of medicinal mushrooms, 19(10), 879-892 (2017-12-20) Substantial fibrin amyloidogenesis in type 2 diabetes assessed using amyloid-selective fluorescent stains.Etheresia Pretorius et al.Cardiovascular diabetology, 16(1), 141-141 (2017-11-04) Reductive Stress: New Insights in Physiology and Drug Tolerance of Mycobacterium.Parminder Singh Mavi et al.Antioxidants & redox signaling, 32(18), 1348-1366 (2019-10-18) Uptake and protective effects of ergothioneine in human endothelial cells.Rachel W S Li et al.The Journal of pharmacology and experimental therapeutics, 350(3), 691-700 (2014-07-16) Functional benefits of ergothioneine and fruit- and vegetable-derived nutraceuticals: overview of the supplemental issue contents.Okezie I Aruoma et al.Preventive medicine, 54 Suppl, S4-S8 (2012-05-18) Gene cloning and characterization of thiourocanate hydratase from Burkholderia sp. HME13.Hisashi Muramatsu et al.Journal of biochemistry, 167(3), 333-341 (2019-11-15) Quantification of L-ergothioneine in whole blood by hydrophilic interaction ultra-performance liquid chromatography and UV-detection.Salvatore Sotgia et al.Journal of separation science, 36(6), 1002-1006 (2013-02-19) Effect of mushroom diet on pharmacokinetics of gabapentin in healthy Chinese subjects.Dorothy Su Lin Toh et al.British journal of clinical pharmacology, 78(1), 129-134 (2013-10-31) OCTN2-Mediated Acetyl-l-Carnitine Transport in Human Pulmonary Epithelial Cells In Vitro.Johanna J Salomon et al.Pharmaceutics, 11(8) (2019-08-10) Comparative study of contents of several bioactive components in fruiting bodies and mycelia of culinary-medicinal mushrooms.Yu-Chang Lo et al.International journal of medicinal mushrooms, 14(4), 357-363 (2012-01-01) N-Alkyl-α-amino acids in Nature and their biocatalytic preparation.Julia F Hyslop et al.Journal of biotechnology, 293, 56-65 (2019-01-29) Substrate Selectivity Check of the Ergothioneine Transporter.Julia Tschirka et al.Drug metabolism and disposition: the biological fate of chemicals, 46(6), 779-785 (2018-03-14) Evolutionary novelty in gravity sensing through horizontal gene transfer and high-order protein assembly.Tu Anh Nguyen et al.PLoS biology, 16(4), e2004920-e2004920 (2018-04-25) The Aspergillus fumigatus protein GliK protects against oxidative stress and is essential for gliotoxin biosynthesis.Lorna Gallagher et al.Eukaryotic cell, 11(10), 1226-1238 (2012-08-21) Characterization of an L-Carnitine Transport System in Murine Photoreceptor Cell Line.Yuta Ohno et al.Biological & pharmaceutical bulletin, 40(12), 2110-2116 (2017-12-05) Chemical Composition and Medicinal Value of Fruiting Bodies and Submerged Cultured Mycelia of Caterpillar Medicinal Fungus Cordyceps militaris CBS-132098 (Ascomycetes).Jannie Siew Lee Chan et al.International journal of medicinal mushrooms, 17(7), 649-659 (2015-11-13) The effect of ergothioneine on clastogenic potential and mutagenic activity: genotoxicity evaluation.Alexander G Schauss et al.International journal of toxicology, 30(4), 405-409 (2011-07-21) L-Ergothioneine scavenges superoxide and singlet oxygen and suppresses TNF-alpha and MMP-1 expression in UV-irradiated human dermal fibroblasts.Kei Obayashi et al.Journal of cosmetic science, 56(1), 17-27 (2005-03-04) The evolutionary history of the genes involved in the biosynthesis of the antioxidant ergothioneine.Gary W Jones et al.Gene, 549(1), 161-170 (2014-07-30) Darcy C Engelhart et al.International journal of molecular sciences, 21(6) (2020-03-19)The SLC22 family of transporters is widely expressed, evolutionarily conserved, and plays a major role in regulating homeostasis by transporting small organic molecules such as metabolites, signaling molecules, and antioxidants. Analysis of transporters in fruit flies provides a simple yet... SAR11 bacteria have a high affinity and multifunctional glycine betaine transporter.Stephen E Noell et al.Environmental microbiology, 21(7), 2559-2575 (2019-05-16) Effect of the King Oyster Culinary-Medicinal Mushroom Pleurotus eryngii (Agaricomycetes) Basidiocarps Powder to Ameliorate Memory and Learning Deficit in Ability in Aβ-Induced Alzheimer's Disease C57BL/6J Mice Model.Chih-Hung Liang et al.International journal of medicinal mushrooms, 22(2), 145-159 (2020-06-02) Redox and Thiols in Archaea.Mamta Rawat et al.Antioxidants (Basel, Switzerland), 9(5) (2020-05-10) Xu, J. and Yadan, J.C. The Journal of Organic Chemistry, 60, 6296-6296 (1995) Involvement of Sulfur in the Biosynthesis of Essential Metabolites in Pathogenic Fungi of Animals, Particularly Aspergillus spp.: Molecular and Therapeutic Implications.Aimee M Traynor et al.Frontiers in microbiology, 10, 2859-2859 (2020-01-11) Shedding light on ovothiol biosynthesis in marine metazoans.Immacolata Castellano et al.Scientific reports, 6, 21506-21506 (2016-02-27) Comparative study of contents of several bioactive components in fruiting bodies and mycelia of culinary-medicinal mushrooms.Shin-Yi Lin et al.International journal of medicinal mushrooms, 15(3), 315-323 (2013-05-15) Depigmenting Effect of Winter Medicinal Mushroom Flammulna velutipes (Higher Basidiomycetes) on Melanoma Cells.Reiko Nagasaka et al.International journal of medicinal mushrooms, 17(6), 511-520 (2015-09-10) Could Ergothioneine Aid in the Treatment of Coronavirus Patients?Irwin K Cheah et al.Antioxidants (Basel, Switzerland), 9(7) (2020-07-11) Edible mushroom (Flammulina velutipes) extract inhibits melanosis in Kuruma shrimp (Marsupenaeus japonicus).Angel B Encarnacion et al.Journal of food science, 76(1), C52-C58 (2011-05-04) Biosynthesis and isolation of selenoneine from genetically modified fission yeast.Nikolaus G Turrini et al.Metallomics : integrated biometal science, 10(10), 1532-1538 (2018-09-25) The proteobacterial species Burkholderia pseudomallei produces ergothioneine, which enhances virulence in mammalian infection.Akshamal M Gamage et al.FASEB journal : official publication of the Federation of American Societies for Experimental Biology, fj201800716-fj201800716 (2018-06-12) Regioselectivity of the oxidative C-S bond formation in ergothioneine and ovothiol biosyntheses.Heng Song et al.Organic letters, 15(18), 4854-4857 (2013-09-11) Comparative in-silico proteomic analysis discerns potential granuloma proteins of Yersinia pseudotuberculosis.Manisha Aswal et al.Scientific reports, 10(1), 3036-3036 (2020-02-23) Preparation of Chaga medicinal mushroom, Inonotus obliquus-fermented rice using solid-state fermentation and its taste quality and antioxidant property.Shin-Yi Lin et al.International journal of medicinal mushrooms, 14(6), 581-592 (2012-01-01) Effects of cysteine and ergothioneine on post-thawed Merino ram sperm and biochemical parameters.Kenan Coyan et al.Cryobiology, 63(1), 1-6 (2011-04-26) Antioxidant properties of fruiting bodies, mycelia, and fermented products of the culinary-medicinal king oyster mushroom, Pleurotus eryngii (higher Basidiomycetes), with high ergothioneine content.Chih-Hung Liang et al.International journal of medicinal mushrooms, 15(3), 267-275 (2013-05-15) Transporter tandems: precise tools for normalizing active transporter in the plasma membrane.Julia Tschirka et al.The Biochemical journal, 477(21), 4191-4206 (2020-10-20) Ergothioneine and related histidine derivatives in the gas phase: tautomer structures determined by IRMPD spectroscopy and theory.Katrin Peckelsen et al.Physical chemistry chemical physics : PCCP, 19(34), 23362-23372 (2017-08-22) Improvement of joint range of motion (ROM) and reduction of chronic pain after consumption of an ergothioneine-containing nutritional supplement.Kathleen F Benson et al.Preventive medicine, 54 Suppl, S83-S89 (2012-02-22) Importance of the novel organic cation transporter 1 for tyrosine kinase inhibition by saracatinib in rheumatoid arthritis synovial fibroblasts.Saliha Harrach et al.Scientific reports, 7(1), 1258-1258 (2017-04-30) The unusual amino acid L-ergothioneine is a physiologic cytoprotectant.B D Paul et al.Cell death and differentiation, 17(7), 1134-1140 (2009-11-17) Quantification of L-ergothioneine in human plasma and erythrocytes by liquid chromatography-tandem mass spectrometry.Ling-Zhi Wang et al.Journal of mass spectrometry : JMS, 48(3), 406-412 (2013-03-16) L-Ergothioneine improves the developmental potential of in vitro sheep embryos without influencing OCTN1-mediated cross-membrane transcript expressionMishra A, et al. Zygote, 26(2), 149-161 (2018) MicroRNA-33 and SIRT1 influence the coronary thrombus burden in hyperglycemic STEMI patients.Nunzia D'Onofrio et al.Journal of cellular physiology, 235(2), 1438-1452 (2019-07-12) Paramount levels of ergothioneine transporter SLC22A4 mRNA in boar seminal vesicles and cross-species analysis of ergothioneine and glutathione in seminal plasma.D Nikodemus et al.Journal of physiology and pharmacology : an official journal of the Polish Physiological Society, 62(4), 411-419 (2011-11-22) The effect of turmeric (Curcuma longa) extract on the functionality of the solute carrier protein 22 A4 (SLC22A4) and interleukin-10 (IL-10) variants associated with inflammatory bowel diseaseMcCann M, et al. Nutrients, 6(10), 4178-4190 (2014) Reactions of L-ergothioneine and some other aminothiones with2,2'-and 4,4'-dipyridyl disulphides and of L-ergothioneine with iodoacetamide. 2-Mercaptoimidazoles, 2- and 4-thiopyridones, thiourea and thioacetamide as highly reactive neutral sulphur nucleophils.J Carlsson et al.The Biochemical journal, 139(1), 221-235 (1974-04-01) Selenoneine, a novel selenium-containing compound, mediates detoxification mechanisms against methylmercury accumulation and toxicity in zebrafish embryo.Michiaki Yamashita et al.Marine biotechnology (New York, N.Y.), 15(5), 559-570 (2013-05-28) Metabolic footprinting of mutant libraries to map metabolite utilization to genotype.Richard Baran et al.ACS chemical biology, 8(1), 189-199 (2012-10-23) Inhibition of amyloid-induced toxicity by ergothioneine in a transgenic Caenorhabditis elegans model.Irwin K Cheah et al.FEBS letters, 593(16), 2139-2150 (2019-06-19) Examining the health effects and bioactive components in Agaricus bisporus mushrooms: a scoping review.Michelle Blumfield et al.The Journal of nutritional biochemistry, 84, 108453-108453 (2020-07-13) The role of thiols in antioxidant systems.Kathrin Ulrich et al.Free radical biology & medicine, 140, 14-27 (2019-06-16) The bioavailability of ergothioneine from mushrooms (Agaricus bisporus) and the acute effects on antioxidant capacity and biomarkers of inflammation.AuBrei J Weigand-Heller et al.Preventive medicine, 54 Suppl, S75-S78 (2012-01-11) The Neurospora crassa mutant NcΔEgt-1 identifies an ergothioneine biosynthetic gene and demonstrates that ergothioneine enhances conidial survival and protects against peroxide toxicity during conidial germination.Marco H Bello et al.Fungal genetics and biology : FG & B, 49(2), 160-172 (2012-01-03) Submerged cultivation of mycelium with high ergothioneine content from the culinary-medicinal king oyster mushroom Pleurotus eryngii (higher Basidiomycetes) and its composition.Chih-Hung Liang et al.International journal of medicinal mushrooms, 15(2), 153-164 (2013-04-06) Snapshots of C-S Cleavage in Egt2 Reveals Substrate Specificity and Reaction Mechanism.Seema Irani et al.Cell chemical biology, 25(5), 519-529 (2018-03-06) Characterization and engineering control of the effects of reactive oxygen species on the conversion of sterols to steroid synthons in Mycobacterium neoaurum.Wan-Ju Sun et al.Metabolic engineering, 56, 97-110 (2019-09-13) Apoptotic Effect of Taiwanofungus salmoneus (Agaricomycetes) Mycelia and Solid-State Fermented Products on Cancer Cells.Rao-Chi Chien et al.International journal of medicinal mushrooms, 19(9), 777-495 (2017-12-05) Biochemistry: Elusive source of sulfur unravelled.Charles E Melançon Nature, 518(7537), 45-46 (2015-01-22) Kinetics of ergothioneine inhibition of mushroom tyrosinase.Wayne C Liao et al.Applied biochemistry and biotechnology, 166(2), 259-267 (2011-11-10) Requirement of ATM in UVA-induced signaling and apoptosis.Yiguo Zhang et al.The Journal of biological chemistry, 277(5), 3124-3131 (2001-11-28) Metabolic coupling of two small-molecule thiols programs the biosynthesis of lincomycin A.Qunfei Zhao et al.Nature, 518(7537), 115-119 (2015-01-22) Impairment of the carnitine/organic cation transporter 1-ergothioneine axis is mediated by intestinal transporter dysfunction in chronic kidney disease.Yasuyuki Shinozaki et al.Kidney international, 92(6), 1356-1369 (2017-07-30) Multiple organic cation transporters contribute to the renal transport of sulpiride.Liping Li et al.Biopharmaceutics & drug disposition, 38(9), 526-534 (2017-09-20) Genotype-phenotype correlation in primary carnitine deficiency.Emily C Rose et al.Human mutation, 33(1), 118-123 (2011-09-17) Utility of winter mushroom treated by atmospheric non-thermal plasma as an alternative for synthetic nitrite and phosphate in ground ham.Kyung Jo et al.Meat science, 166, 108151-108151 (2020-04-20)

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