
Atropic acid | CAS:492-38-6
Atropic acid
- 名称:2-苯基丙烯酸; 阿托酸 | Atropic acid
- CAS号:492-38-6
- 别名:2-Phenylpropenoic acid
- 分子式:C9H8O2
- 分子量:148.16
- EINESC号:207-753-6
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物理化学性质
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Licochalcone A bound to bovine serum albumin: a spectroscopic, photophysical and structural study.Sandra Monti et al.Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology, 8(6), 805-813 (2009-06-06)
Induction of NAD(P)H:Quinone Oxidoreductase 1 (NQO1) by Glycyrrhiza Species Used for Women's Health: Differential Effects of the Michael Acceptors Isoliquiritigenin and Licochalcone A.Atieh Hajirahimkhan et al.Chemical research in toxicology, 28(11), 2130-2141 (2015-10-17)
Ion Channels Induced by Antimicrobial Agents in Model Lipid Membranes are Modulated by Plant Polyphenols Through Surrounding Lipid Media.Svetlana S Efimova et al.The Journal of membrane biology, 251(4), 551-562 (2018-03-20)
Lonicerin, an anti-algE flavonoid against Pseudomonas aeruginosa virulence screened from Shuanghuanglian formula by molecule docking based strategy.Zhongren Xu et al.Journal of ethnopharmacology, 239, 111909-111909 (2019-04-27)
Comparative trial of moisturizer containing licochalcone A vs. hydrocortisone lotion in the treatment of childhood atopic dermatitis: a pilot study.M Udompataikul et al.Journal of the European Academy of Dermatology and Venereology : JEADV, 25(6), 660-665 (2010-09-16)
Effect of licochalcone A on growth and properties of Streptococcus suis.Huaijie Hao et al.PloS one, 8(7), e67728-e67728 (2013-08-13)
Toxicity and Synergistic Activities of Chalcones Against Aedes aegypti (Diptera: Culicidae) and Drosophila melanogaster (Diptera: Drosophilidae).Aaron D Gross et al.Journal of medical entomology, 54(2), 382-386 (2016-12-25)
Cytochrome P450 inhibition by three licorice species and fourteen licorice constituents.Guannan Li et al.European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences, 109, 182-190 (2017-08-05)
Design, synthesis, and evaluation of bromo-retrochalcone derivatives as protein tyrosine phosphatase 1B inhibitors.Zhiguo Liu et al.Bioorganic & medicinal chemistry letters, 21(12), 3755-3758 (2011-05-11)
Antibacterial activity of licochalcone A against spore-forming bacteria.Ryo-Ichi Tsukiyama et al.Antimicrobial agents and chemotherapy, 46(5), 1226-1230 (2002-04-18)
Licochalcone A inhibits growth of gastric cancer cells by arresting cell cycle progression and inducing apoptosis.Xiu-ying Xiao et al.Cancer letters, 302(1), 69-75 (2011-01-11)
New Synthetic 3-Benzoyl-5-Hydroxy-2H-Chromen-2-One (LM-031) Inhibits Polyglutamine Aggregation and Promotes Neurite Outgrowth through Enhancement of CREB, NRF2, and Reduction of AMPKα in SCA17 Cell Models.Chiung-Mei Chen et al.Oxidative medicine and cellular longevity, 2020, 3129497-3129497 (2020-05-08)
Chalcones enhance TRAIL-induced apoptosis in prostate cancer cells.Ewelina Szliszka et al.International journal of molecular sciences, 11(1), 1-13 (2010-02-18)
Randomized, double-blind, split-side, comparison study of moisturizer containing licochalcone A and 1% hydrocortisone in the treatment of childhood atopic dermatitis.Siriwan Wananukul et al.Journal of the Medical Association of Thailand = Chotmaihet thangphaet, 96(9), 1135-1142 (2013-10-30)
Hepatic metabolism of licochalcone A, a potential chemopreventive chalcone from licorice (Glycyrrhiza inflata), determined using liquid chromatography-tandem mass spectrometry.Lingyi Huang et al.Analytical and bioanalytical chemistry, 409(30), 6937-6948 (2017-11-12)
Anti-obesity potential of Glycyrrhiza uralensis and licochalcone A through induction of adipocyte browning.Hye Eun Lee et al.Biochemical and biophysical research communications, 503(3), 2117-2123 (2018-08-11)
Subinhibitory concentrations of licochalcone A decrease alpha-toxin production in both methicillin-sensitive and methicillin-resistant Staphylococcus aureus isolates.J Qiu et al.Letters in applied microbiology, 50(2), 223-229 (2009-12-23)
Licochalcone A is a potent inhibitor of TEL-Jak2-mediated transformation through the specific inhibition of Stat3 activation.Megumi Funakoshi-Tago et al.Biochemical pharmacology, 76(12), 1681-1693 (2008-10-14)
Structure and properties of licochalcone A-human serum albumin complexes in solution: a spectroscopic, photophysical and computational approach to understand drug-protein interaction.Sandra Monti et al.Physical chemistry chemical physics : PCCP, 10(44), 6597-6606 (2008-11-08)
The fixed structure of Licochalcone A by alpha, beta-unsaturated ketone is necessary for anti-inflammatory activity through the inhibition of NF-kappaB activation.Megumi Funakoshi-Tago et al.International immunopharmacology, 10(5), 562-571 (2010-02-16)
Phytochemical licochalcone A enhances antimalarial activity of artemisinin in vitro.Lokesh C Mishra et al.Acta tropica, 109(3), 194-198 (2008-12-10)
Antitumor and antimetastatic effects of licochalcone A in mouse models.Jin-Kyung Kim et al.Journal of molecular medicine (Berlin, Germany), 88(8), 829-838 (2010-04-13)
Effects of licochalcone A on the bioavailability and pharmacokinetics of nifedipine in rats: possible role of intestinal CYP3A4 and P-gp inhibition by licochalcone A.Jin-Seok Choi et al.Biopharmaceutics & drug disposition, 35(7), 382-390 (2014-06-07)
Licochalcone A prevents adipocyte differentiation and lipogenesis via suppression of peroxisome proliferator-activated receptor γ and sterol regulatory element-binding protein pathways.Hai-Yan Quan et al.Journal of agricultural and food chemistry, 60(20), 5112-5120 (2012-05-09)
Cranberry proanthocyanidins act in synergy with licochalcone A to reduce Porphyromonas gingivalis growth and virulence properties, and to suppress cytokine secretion by macrophages.M Feldman et al.Journal of applied microbiology, 113(2), 438-447 (2012-05-09)
Synergistic antimetastatic effect of cotreatment with licochalcone A and sorafenib on human hepatocellular carcinoma cells through the inactivation of MKK4/JNK and uPA expression.Min-Hua Wu et al.Environmental toxicology, 33(12), 1237-1244 (2018-09-07)
Licochalcone-A, a novel flavonoid isolated from licorice root (Glycyrrhiza glabra), causes G2 and late-G1 arrests in androgen-independent PC-3 prostate cancer cells.Yue Fu et al.Biochemical and biophysical research communications, 322(1), 263-270 (2004-08-18)
Streptococcus suis biofilm: regulation, drug-resistance mechanisms, and disinfection strategies.Yang Wang et al.Applied microbiology and biotechnology (2018-09-14)
Anti-proliferative effect of licochalcone A on vascular smooth muscle cells.Jin-Hee Park et al.Biological & pharmaceutical bulletin, 31(11), 1996-2000 (2008-11-05)
Protective Effects of Licochalcone A Improve Airway Hyper-Responsiveness and Oxidative Stress in a Mouse Model of Asthma.Wen-Chung Huang et al.Cells, 8(6) (2019-06-23)
Guanylate cyclase activator YC-1 potentiates apoptotic effect of licochalcone A on human epithelial ovarian carcinoma cells via activation of death receptor and mitochondrial pathways.Chung Soo Lee et al.European journal of pharmacology, 683(1-3), 54-62 (2012-04-03)
Licochalcone A significantly suppresses LPS signaling pathway through the inhibition of NF-kappaB p65 phosphorylation at serine 276.Jun-ichi Furusawa et al.Cellular signalling, 21(5), 778-785 (2009-01-27)
Licochalcone A inhibits the migration and invasion of human lung cancer cells via inactivation of the Akt signaling pathway with downregulation of MMP-1/-3 expression.Hung-Che Huang et al.Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine, 35(12), 12139-12149 (2014-08-26)
Influence of subinhibitory concentrations of licochalcone A on the secretion of enterotoxins A and B by Staphylococcus aureus.Jiazhang Qiu et al.FEMS microbiology letters, 307(2), 135-141 (2010-04-24)
Licochalcone A Suppresses the Proliferation of Osteosarcoma Cells through Autophagy and ATM-Chk2 Activation.Tai-Shan Shen et al.Molecules (Basel, Switzerland), 24(13) (2019-07-05)
Protective effect of Jie-Geng-Tang against Staphylococcus aureus induced acute lung injury in mice and discovery of its effective constituents.Yining Liu et al.Journal of ethnopharmacology, 243, 112076-112076 (2019-07-12)
In vitro and in vivo osteogenic activity of licochalcone A.Soon Nam Kim et al.Amino acids, 42(4), 1455-1465 (2011-04-07)
Licochalcone a inhibits lipopolysaccharide-induced inflammatory response in vitro and in vivo.Xiao Chu et al.Journal of agricultural and food chemistry, 60(15), 3947-3954 (2012-03-10)
The antiparasitic compound licochalcone a is a potent echinocytogenic agent that modifies the erythrocyte membrane in the concentration range where antiplasmodial activity is observed.Hanne L Ziegler et al.Antimicrobial agents and chemotherapy, 48(10), 4067-4071 (2004-09-25)
Licorice and licochalcone-A induce autophagy in LNCaP prostate cancer cells by suppression of Bcl-2 expression and the mTOR pathway.Yi-Te Yo et al.Journal of agricultural and food chemistry, 57(18), 8266-8273 (2009-08-29)
Effects of licochalcon A on the pharmacokinetics of losartan and its active metabolite, EXP-3174, in rats.J S Choi et al.Die Pharmazie, 68(11), 882-888 (2014-01-02)
Antiangiogenic effect of licochalcone A.Yoon Hee Kim et al.Biochemical pharmacology, 80(8), 1152-1159 (2010-07-20)
[Advance in studies on pharmacological effects of licochalcone A].Hong Zhao et al.Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, 38(22), 3814-3818 (2014-02-25)
Licochalcones suppress degranulation by decreasing the intracellular Ca2+ level and tyrosine phosphorylation of ERK in RBL-2H3 cells.Shota Tanifuji et al.International immunopharmacology, 10(7), 769-776 (2010-04-20)
Preparation and evaluation of 3 m open tubular capillary columns with a zwitterionic polymeric porous layer for liquid chromatography.Li Peng et al.Journal of separation science, 39(19), 3736-3744 (2016-08-12)
Protective Effects of Licochalcone A Ameliorates Obesity and Non-Alcoholic Fatty Liver Disease Via Promotion of the Sirt-1/AMPK Pathway in Mice Fed a High-Fat Diet.Chian-Jiun Liou et al.Cells, 8(5) (2019-05-15)
Glycyrrhiza inflata-derived chalcones, Licochalcone A, Licochalcone B and Licochalcone D, inhibit phosphorylation of NF-kappaB p65 in LPS signaling pathway.Jun-ichi Furusawa et al.International immunopharmacology, 9(4), 499-507 (2009-03-18)
Effects of natural nuclear factor-kappa B inhibitors on anticancer drug efflux transporter human P-glycoprotein.Tomohiro Nabekura et al.Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 70, 140-145 (2015-03-18)
Up-regulation of licochalcone A biosynthesis and secretion by Tween 80 in hairy root cultures of Glycyrrhiza uralensis Fisch.Hai-Chao Zhang et al.Molecular biotechnology, 47(1), 50-56 (2010-07-08)
Effect of licorice compounds licochalcone A, glabridin and glycyrrhizic acid on growth and virulence properties of Candida albicans.Céline Messier et al.Mycoses, 54(6), e801-e806 (2011-05-28)
Chemical profiling and quantification of Gua-Lou-Gui-Zhi decoction by high performance liquid chromatography/quadrupole-time-of-flight mass spectrometry and ultra-performance liquid chromatography/triple quadrupole mass spectrometry.Wen Xu et al.Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 986-987, 69-84 (2015-02-25)
Licochalcone A potently inhibits tumor necrosis factor alpha-induced nuclear factor-kappaB activation through the direct inhibition of IkappaB kinase complex activation.Megumi Funakoshi-Tago et al.Molecular pharmacology, 76(4), 745-753 (2009-07-14)
Licochalcone A, a polyphenol present in licorice, suppresses UV-induced COX-2 expression by targeting PI3K, MEK1, and B-Raf.Nu Ry Song et al.International journal of molecular sciences, 16(3), 4453-4470 (2015-02-25)
Licochalcone A Induced Suicidal Death of Human Erythrocytes.Jasmin Egler et al.Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology, 37(5), 2060-2070 (2015-11-20)
Chinese Herbal Medicine Glycyrrhiza inflataReduces Aβ Aggregation and Exerts Neuroprotection through Anti-Oxidation and Anti-Inflammation.Ya-Jen Chiu et al.The American journal of Chinese medicine, 1-25 (2018-10-05)
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