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4-Diethylamino-2-methylbenzaldehyde | CAS:92-14-8
4-Diethylamino-2-methylbenzaldehyde
  • 名称:4-(二乙氨基)-2-甲基苯甲醛; N,N-二乙基-4-氨基-2-甲基苯甲醛 | 4-Diethylamino-2-methylbenzaldehyde
  • CAS号:92-14-8
  • 别名:N,N-Diethyl-4-amino-2-methylbenzaldehyde
  • 分子式:C12H17NO
  • 分子量:191.27
  • EINESC号:202-130-5

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Autoantibodies enhance agonist action and binding to cardiac muscarinic receptors in chronic Chagas' disease.Ciria C Hernandez et al.Journal of receptor and signal transduction research, 28(4), 375-401 (2008-08-15) Peculiar effects of muscarinic M1, M2, and M3 receptor blockers on cardiac chronotropic function in neonatal rats.N I Ziyatdinova et al.Bulletin of experimental biology and medicine, 154(1), 1-2 (2013-01-19) [Three auxiliary medications in obstetrics. 1955].Luis Andrés Lagarde et al.Ginecologia y obstetricia de Mexico, 78(11), 633-641 (2011-02-09) [Neuromuscular monitoring: methods and machines].Dirk Nauheimer et al.Anasthesiologie, Intensivmedizin, Notfallmedizin, Schmerztherapie : AINS, 43(5), 374-381 (2008-05-09) Peripheral binding site is involved in the neurotrophic activity of acetylcholinesterase.F J Muñoz et al.Neuroreport, 10(17), 3621-3625 (2000-01-05) Subtype-selective blockade of cardiac muscarinic receptors inhibits vagal chronotropic responses in cats.Oleg E Osadchii Pflugers Archiv : European journal of physiology, 455(5), 819-828 (2007-09-28) Branching points of primary afferent fibers are vital for the modulation of fiber excitability by epidural DC polarization and by GABA in the rat spinal cord.Yaqing Li et al.Journal of neurophysiology, 124(1), 49-62 (2020-05-28) Binding of orthosteric ligands to the allosteric site of the M(2) muscarinic cholinergic receptor.Dar'ya S Redka et al.Molecular pharmacology, 74(3), 834-843 (2008-06-17) Use of acetylcholine mustard to study allosteric interactions at the M(2) muscarinic receptor.Hinako Suga et al.The Journal of pharmacology and experimental therapeutics, 327(2), 518-528 (2008-08-07) Stimulus-dependent augmented gamma oscillatory activity between the functionally connected cortical neurons in the primary visual cortex.Vishal Bharmauria et al.The European journal of neuroscience, 41(12), 1587-1596 (2015-04-08) Acetylcholine mediates the release of IL-8 in human bronchial epithelial cells by a NFkB/ERK-dependent mechanism.Mirella Profita et al.European journal of pharmacology, 582(1-3), 145-153 (2008-02-05) Kinetics of inhibition of acetylcholinesterase in the presence of acetonitrile.Markus Pietsch et al.The FEBS journal, 276(8), 2292-2307 (2009-03-19) Investigating the interaction of McN-A-343 with the M2 muscarinic receptor using its nitrogen mustard derivative.Hinako Suga et al.Biochemical pharmacology, 79(7), 1025-1035 (2009-11-17) Transcriptional response to muscarinic acetylcholine receptor stimulation: regulation of Egr-1 biosynthesis by ERK, Elk-1, MKP-1, and calcineurin in carbachol-stimulated human neuroblastoma cellsRossler O, et al. Archives of Biochemistry and Biophysics, 470(1), 93-102 (2008) First gallamine-tacrine hybrid: design and characterization at cholinesterases and the M2 muscarinic receptor.Paul W Elsinghorst et al.Journal of medicinal chemistry, 50(23), 5685-5695 (2007-10-20) Differential effects of "peripheral" site ligands on Torpedo and chicken acetylcholinesterase.J Eichler et al.Molecular pharmacology, 45(2), 335-340 (1994-02-01) Peripheral sensory coding through oscillatory synchrony in weakly electric fish.Christa A Baker et al.eLife, 4, e08163-e08163 (2015-08-05) Acute anal stretch inhibits NMDA-dependent pelvic-urethra reflex potentiation via spinal GABAergic inhibition in anesthetized rats.Sung-Lang Chen et al.American journal of physiology. Renal physiology, 295(4), F923-F931 (2008-07-18) Spinal sensory projection neuron responses to spinal cord stimulation are mediated by circuits beyond gate control.Tianhe C Zhang et al.Journal of neurophysiology, 114(1), 284-300 (2015-05-15) Neuromuscular blocking drugs: discovery and developmentRaghavendra T Journal of the Royal Society of Medicine, 95(7), 363-367 (2002) The impact of orthosteric radioligand depletion on the quantification of allosteric modulator interactions.Vimesh A Avlani et al.The Journal of pharmacology and experimental therapeutics, 325(3), 927-934 (2008-03-07) Translating clinical findings into knowledge in drug safety evaluation--drug induced liver injury prediction system (DILIps).Zhichao Liu et al.PLoS computational biology, 7(12), e1002310-e1002310 (2011-12-24) Local Circuits for Contrast Normalization and Adaptation Investigated with Two-Photon Imaging in Cat Primary Visual Cortex.Andreas J Keller et al.The Journal of neuroscience : the official journal of the Society for Neuroscience, 35(27), 10078-10087 (2015-07-15) Exploration of the orthosteric/allosteric interface in human M1 muscarinic receptors by bitopic fluorescent ligands.Sandrine B Daval et al.Molecular pharmacology, 84(1), 71-85 (2013-04-23) The effect of memantine and levodopa/carbidopa on the responses of phrenic nerve-diaphragm preparations from aged rats.Soha Ali El-Moursy et al.Medical science monitor : international medical journal of experimental and clinical research, 15(11), BR339-BR348 (2009-10-30) Development of a radioligand, [(3)H]LY2119620, to probe the human M(2) and M(4) muscarinic receptor allosteric binding sites.Douglas A Schober et al.Molecular pharmacology, 86(1), 116-123 (2014-05-09) Role of acidic amino acids in the allosteric modulation by gallamine of antagonist binding at the m2 muscarinic acetylcholine receptor.R A Leppik et al.Molecular pharmacology, 45(5), 983-990 (1994-05-01) Long-range neural inhibition and stimulus competition in the archerfish optic tectum.Svetlana Volotsky et al.Journal of comparative physiology. A, Neuroethology, sensory, neural, and behavioral physiology, 205(4), 537-552 (2019-05-28) [Intravenous procaine as analgesic in obstetrics. 1955].Ignacio Lima-Morales Ginecologia y obstetricia de Mexico, 79(2), 97-104 (2011-10-05) An in vitro model for studying neuromuscular transmission in the mouse pharynx.Olle Ekberg et al.Dysphagia, 24(1), 32-39 (2008-04-26) A fluorescence resonance energy transfer-based M2 muscarinic receptor sensor reveals rapid kinetics of allosteric modulation.Monika Maier-Peuschel et al.The Journal of biological chemistry, 285(12), 8793-8800 (2010-01-20) Site-directed mutagenesis reveals two epitopes involved in the subtype selectivity of the allosteric interactions of gallamine at muscarinic acetylcholine receptors.A L Gnagey et al.Molecular pharmacology, 56(6), 1245-1253 (1999-11-26) Chemical genetics reveals a complex functional ground state of neural stem cells.Phedias Diamandis et al.Nature chemical biology, 3(5), 268-273 (2007-04-10) Developing structure-activity relationships for the prediction of hepatotoxicity.Nigel Greene et al.Chemical research in toxicology, 23(7), 1215-1222 (2010-06-18) Cross-talk between transforming growth factor-β₁ and muscarinic M₂ receptors augments airway smooth muscle proliferation.Tjitske A Oenema et al.American journal of respiratory cell and molecular biology, 49(1), 18-27 (2013-03-02) A fluorescence anisotropy assay for the muscarinic M1 G-protein-coupled receptor.Kristin G Huwiler et al.Assay and drug development technologies, 8(3), 356-366 (2010-03-18) Hydrogen Sulfide Mediating both Excitatory and Inhibitory Effects in a Rat Model of Meningeal Nociception and Headache Generation.Christiane Teicher et al.Frontiers in neurology, 8, 336-336 (2017-08-05) A predictive ligand-based Bayesian model for human drug-induced liver injury.Sean Ekins et al.Drug metabolism and disposition: the biological fate of chemicals, 38(12), 2302-2308 (2010-09-17) Regulation of blood flow in the retinal trilaminar vascular network.Tess E Kornfield et al.The Journal of neuroscience : the official journal of the Society for Neuroscience, 34(34), 11504-11513 (2014-08-22) Dexmedetomidine and regulation of splenic sympathetic nerve discharge in aged F344 rats.R M McMurphy et al.Autonomic neuroscience : basic & clinical, 190, 53-57 (2015-03-31) Androgens increase lws opsin expression and red sensitivity in male three-spined sticklebacks.Yi Ta Shao et al.PloS one, 9(6), e100330-e100330 (2014-06-26) Development of a phospholipidosis database and predictive quantitative structure-activity relationship (QSAR) models.Naomi L Kruhlak et al.Toxicology mechanisms and methods, 18(2-3), 217-227 (2008-01-01) A novel fast mechanism for GPCR-mediated signal transduction--control of neurotransmitter release.Yonatan M Kupchik et al.The Journal of cell biology, 192(1), 137-151 (2011-01-05) M2 muscarinic acetylcholine receptors regulate long-term potentiation at hippocampal CA3 pyramidal cell synapses in an input-specific fashion.Fang Zheng et al.Journal of neurophysiology, 108(1), 91-100 (2012-04-12) Superficial layer pyramidal cells communicate heterogeneously between multiple functional domains of cat primary visual cortex.Kevan A C Martin et al.Nature communications, 5, 5252-5252 (2014-10-25) Changes in blood pressure induced by electrical stimulation of the femur in anesthetized rats.Atsuko Suzuki et al.Autonomic neuroscience : basic & clinical, 158(1-2), 39-43 (2010-06-29) Pop-out in visual search of moving targets in the archer fish.Mor Ben-Tov et al.Nature communications, 6, 6476-6476 (2015-03-11) The inhibitory effect of gallamine on muscarinic receptorsClark AL and Mitchelson F British Journal of Pharmacology, 58(3), 323-331 (1976) Role of TNF-α in virus-induced airway hyperresponsiveness and neuronal M₂ muscarinic receptor dysfunction.Zhenying Nie et al.British journal of pharmacology, 164(2b), 444-452 (2011-04-05) Functional and direct binding studies using subtype selective muscarinic receptor antagonists.E L Kunysz et al.British journal of pharmacology, 93(3), 491-500 (1988-03-01) Using a radioalloster to test predictions of the cooperativity model for gallamine binding to the allosteric site of muscarinic acetylcholine M(2) receptors.C Tränkle et al.Molecular pharmacology, 56(5), 962-965 (1999-10-26) Heterotropic cooperativity within and between protomers of an oligomeric M(2) muscarinic receptor.Rabindra V Shivnaraine et al.Biochemistry, 51(22), 4518-4540 (2012-05-04) Rebamipide suppresses mite-induced asthmatic responses in NC/Nga mice.Ikuo Murakami et al.American journal of physiology. Lung cellular and molecular physiology, 309(8), L872-L878 (2015-10-17) Two-state models and the analysis of the allosteric effect of gallamine at the M2 muscarinic receptor.Frederick J Ehlert et al.The Journal of pharmacology and experimental therapeutics, 325(3), 1039-1060 (2008-02-29)
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