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5,11-Dimethyl-6H-pyrido[4,3-b]carbazole | CAS:519-23-3
5,11-Dimethyl-6H-pyrido[4,3-b]carbazole
  • 名称:5,11-二甲基-6H-吡啶并[4,3-b]咔唑; 椭圆玫瑰树碱; 玫瑰树碱 | 5,11-Dimethyl-6H-pyrido[4,3-b]carbazole
  • CAS号:519-23-3
  • 别名:Ellipticine
  • 分子式:C17H14N2
  • 分子量:246.31
  • EINESC号:208-264-0

产品描述

物理化学性质

熔点 313 ºC**
密度 1.257±0.06 g/cm3 (20 º

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High resolution 1H spectra of powdered solids observed by Hahn echo pulse sequence with magic-angle spinning.J Z Hu et al.Solid state nuclear magnetic resonance, 6(1), 85-94 (1996-02-01) Creep-resistant elastomeric networks prepared by photocrosslinking fumaric acid monoethyl ester-functionalized poly(trimethylene carbonate) oligomers.Qingpu Hou et al.Acta biomaterialia, 5(5), 1543-1551 (2009-01-31) The use of differential transverse relaxation to detect mobile species in solids.B C Gerstein et al.Solid state nuclear magnetic resonance, 6(1), 63-71 (1996-02-01) An atom-economical approach to conformationally constrained tricyclic nitrogen heterocycles via sequential and tandem Ugi/intramolecular Diels-Alder reaction of pyrrole.K Paulvannan The Journal of organic chemistry, 69(4), 1207-1214 (2004-02-14) Tolerance of DNA Replication Stress Is Promoted by Fumarate Through Modulation of Histone Demethylation and Enhancement of Replicative Intermediate Processing in Saccharomyces cerevisiae.Faeze Saatchi et al.Genetics, 212(3), 631-654 (2019-05-28) Rapid photo-crosslinking of fumaric acid monoethyl ester-functionalized poly(trimethylene carbonate) oligomers for drug delivery applications.Janine Jansen et al.Journal of controlled release : official journal of the Controlled Release Society, 147(1), 54-61 (2010-07-21) Antiproliferative and cytotoxic profiles of antipsoriatic fumaric acid derivatives in keratinocyte cultures.B Sebök et al.European journal of pharmacology, 270(1), 79-87 (1994-01-03) Fumaric acid derivatives evoke a transient increase in intracellular free calcium concentration and inhibit the proliferation of human keratinocytes.H B Thio et al.The British journal of dermatology, 131(6), 856-861 (1994-12-01) In vitro pharmacokinetics of anti-psoriatic fumaric acid esters.Nicolle H R Litjens et al.BMC pharmacology, 4, 22-22 (2004-10-14) Presystemic metabolism and intestinal absorption of antipsoriatic fumaric acid esters.D Werdenberg et al.Biopharmaceutics & drug disposition, 24(6), 259-273 (2003-09-16) The effect of fumaric acid esters and dithranol on acanthosis and hyperproliferation in psoriasis vulgaris.M Bacharaçh-Buhles et al.Acta dermato-venereologica, 76(3), 190-193 (1996-05-01) Preparation of hydrogels by photo-crosslinking of fumaric acid monoethyl ester (fame) functionalized oligomers.Q Hou et al.Journal of controlled release : official journal of the Controlled Release Society, 101(1-3), 335-337 (2005-03-09) Photo-crosslinked networks prepared from fumaric acid monoethyl ester-functionalized poly(D,L-lactic acid) oligomers and N-vinyl-2-pyrrolidone for the controlled and sustained release of proteins.Janine Jansen et al.Acta biomaterialia, 8(10), 3652-3659 (2012-06-19) Fumaric acid monoethyl ester-functionalized poly(D,L-lactide)/N-vinyl-2-pyrrolidone resins for the preparation of tissue engineering scaffolds by stereolithography.Janine Jansen et al.Biomacromolecules, 10(2), 214-220 (2008-12-19) Treatment of recurrent aphthous stomatitis with fumaric acid esters.Emmanuella Guenova et al.Archives of dermatology, 147(3), 282-284 (2011-03-23) Preparation of biodegradable networks by photo-crosslinking lactide, epsilon-caprolactone and trimethylene carbonate-based oligomers functionalized with fumaric acid monoethyl ester.Dirk W Grijpma et al.Biomaterials, 26(16), 2795-2802 (2004-12-18) Successful treatment of recalcitrant cutaneous sarcoidosis with fumaric acid esters.Ute Nowack et al.BMC dermatology, 2, 15-15 (2002-12-25) [Efficacy and safety profile of fumaric acid esters in oral long-term therapy with severe treatment refractory psoriasis vulgaris. A study of 83 patients].P Altmeyer et al.Der Hautarzt; Zeitschrift fur Dermatologie, Venerologie, und verwandte Gebiete, 47(3), 190-196 (1996-03-01) Treatment of psoriasis with fumaric acid esters: results of a prospective multicentre study. German Multicentre Study.U Mrowietz et al.The British journal of dermatology, 138(3), 456-460 (1998-05-15) Structure-activity relationships of trans-substituted-propenoic acid derivatives on the nicotinic acid receptor HCA2 (GPR109A).J P D van Veldhoven et al.Bioorganic & medicinal chemistry letters, 21(9), 2736-2739 (2010-12-21) Photo-crosslinked biodegradable hydrogels prepared from fumaric acid monoethyl ester-functionalized oligomers for protein delivery.Janine Jansen et al.Macromolecular bioscience, 12(5), 692-702 (2012-03-15) Spectral editing in 13C CP/MAS experiments at high magnetic field.J Z Hu et al.Solid state nuclear magnetic resonance, 6(2), 187-196 (1996-04-01) Krebs-cycle-deficient hereditary cancer syndromes are defined by defects in homologous-recombination DNA repair.Parker L Sulkowski et al.Nature genetics, 50(8), 1086-1092 (2018-07-18) Fumaric acid esters in necrobiosis lipoidica: results of a prospective noncontrolled study.A Kreuter et al.The British journal of dermatology, 153(4), 802-807 (2005-09-27) Treatment of disseminated granuloma annulare with fumaric acid esters.Alexander Kreuter et al.BMC dermatology, 2, 5-5 (2002-03-27) Fumarate analogs act as allosteric inhibitors of the human mitochondrial NAD(P)+-dependent malic enzyme.Ju-Yi Hsieh et al.PloS one, 9(6), e98385-e98385 (2014-06-10) Antipsoriatic effect of fumaric acid derivatives. Results of a multicenter double-blind study in 100 patients.P J Altmeyer et al.Journal of the American Academy of Dermatology, 30(6), 977-981 (1994-06-01) Dimethylfumarate is an inhibitor of cytokine-induced E-selectin, VCAM-1, and ICAM-1 expression in human endothelial cells.M Vandermeeren et al.Biochemical and biophysical research communications, 234(1), 19-23 (1997-05-08) [Therapy of psoriasis with fumaderm preparation].A Zesch Der Hautarzt; Zeitschrift fur Dermatologie, Venerologie, und verwandte Gebiete, 46(12), 875-876 (1995-12-01) Treatment of severe psoriasis with fumaric acid esters: scientific background and guidelines for therapeutic use. The German Fumaric Acid Ester Consensus Conference.U Mrowietz et al.The British journal of dermatology, 141(3), 424-429 (1999-12-03)
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