没有数据	没有数据

没有数据	没有数据

来源	SDS样本
没有数据	没有数据

产品合成路线

更多

名称	CAS号

更多

文章

同行评议文献

Peroxisome proliferator-activated receptor alpha induction of uncoupling protein 2 protects against acetaminophen-induced liver toxicity.Andrew D Patterson et al.Hepatology (Baltimore, Md.), 56(1), 281-290 (2012-02-10) Two Isomeric C16 Oxo-Fatty Acids from the Diatom Chaetoceros karianus Show Dual Agonist Activity towards Human Peroxisome Proliferator-Activated Receptors (PPARs) alphagammaMoldes-Anaya A, et al. Marine drugs, 15(6), 148-148 (2017) Attenuation of acute pancreatitis by peroxisome proliferator-activated receptor-α in rats: the effect on Toll-like receptor signaling pathways.Jun-Li Ding et al.Pancreas, 42(1), 114-122 (2012-06-23) PPAR-alpha activation mediates innate host defense through induction of TFEB and lipid catabolismKim YS, et al. Journal of Immunology, 198(8), 3283-3295 (2017) Detailed transcriptomics analysis of the effect of dietary fatty acids on gene expression in the heart.Anastasia Georgiadi et al.Physiological genomics, 44(6), 352-361 (2012-01-26) A Comparison of the TempO-Seq S1500+ Platform to RNA-Seq and Microarray Using Rat Liver Mode of Action Samples.Pierre R Bushel et al.Frontiers in genetics, 9, 485-485 (2018-11-14) PPAR-alpha activation as a preconditioning-like intervention in rats in vivo confers myocardial protection against acute ischaemia-reperfusion injury: involvement of PI3K-Akt.Táňa Ravingerová et al.Canadian journal of physiology and pharmacology, 90(8), 1135-1144 (2012-07-20) WY-14643, a selective agonist of peroxisome proliferator-activated receptor-alpha, ameliorates lipopolysaccharide-induced depressive-like behaviors by preventing neuroinflammation and oxido-nitrosative stress in miceYang R, et al. Pharmacology, Biochemistry, and Behavior, 153, 97-104 (2017) Proteome analysis identified the PPARγ ligand 15d-PGJ2 as a novel drug inhibiting melanoma progression and interfering with tumor-stroma interaction.Verena Paulitschke et al.PloS one, 7(9), e46103-e46103 (2012-10-11) PPARα agonist Wy14643 suppresses cathepsin B in human endothelial cells via transcriptional, post-transcriptional and post-translational mechanisms.Gabi Reichenbach et al.Angiogenesis, 16(1), 223-233 (2012-10-26) Satellite glial cells promote regenerative growth in sensory neurons.Oshri Avraham et al.Nature communications, 11(1), 4891-4891 (2020-10-01) Topical application of PPARα (but not β/δ or γ) suppresses atopic dermatitis in NC/Nga mice.T Chiba et al.Allergy, 67(7), 936-942 (2012-05-16) Peroxisome proliferator-activated receptor α positively regulates complement C3 expression but inhibits tumor necrosis factor α-mediated activation of C3 gene in mammalian hepatic-derived cells.Denis A Mogilenko et al.The Journal of biological chemistry, 288(3), 1726-1738 (2012-11-22) Functional analyses of the crohn?s disease risk gene LACC1Assadi G, et al. PLoS ONE, 11(12), e0168276-e0168276 (2016) Tertiary alkylamines as nucleophiles in substitution reactions at heteroaromatic halide during the synthesis of the highly potent pirinixic acid derivative 2-(4-chloro-6-(2,3-dimethylphenylamino)pyrimidin-2-ylthio)octanoic acid (YS-121).Matthias Gabler et al.Molecules (Basel, Switzerland), 16(12), 10013-10028 (2011-12-07) Activation of peroxisome proliferator activated receptor alpha ameliorates ethanol induced steatohepatitis in mice.Lingbo Kong et al.Lipids in health and disease, 10, 246-246 (2012-01-03) In vivo imaging reveals selective PPAR activity in the skin of peroxisome proliferator-activated receptor responsive element-luciferase reporter mice.Noura El-Jamal et al.Experimental dermatology, 22(2), 137-140 (2013-02-01) Betulinic acid alleviates endoplasmic reticulum stress-mediated nonalcoholic fatty liver disease through activation of farnesoid X receptors in mice.Ming Gu et al.British journal of pharmacology, 176(7), 847-863 (2019-01-13) Treatment with pharmacological PPARα agonists stimulates the ubiquitin proteasome pathway and myofibrillar protein breakdown in skeletal muscle of rodents.Robert Ringseis et al.Biochimica et biophysica acta, 1830(1), 2105-2117 (2012-10-09) Peroxisome proliferator-activated receptor ɑ (PPARɑ)-cytochrome P450 epoxygenases-soluble epoxide hydrolase axis in ER + PR + HER2- breast cancer.Zdenek Tauber et al.Medical molecular morphology, 53(3), 141-148 (2019-12-12) The UDP-Glycosyltransferase (UGT) Superfamily: New Members, New Functions, and Novel Paradigms.Robyn Meech et al.Physiological reviews, 99(2), 1153-1222 (2019-02-07) Direct transcriptional regulation of human hepatic cytochrome P450 3A4 (CYP3A4) by peroxisome proliferator-activated receptor alpha (PPARα).Maria Thomas et al.Molecular pharmacology, 83(3), 709-718 (2013-01-09) Activation of peroxisome proliferator activated receptor alpha ameliorates ethanol mediated liver fibrosis in mice.Yue-Min Nan et al.Lipids in health and disease, 12, 11-11 (2013-02-08) MDM2 and MDMX promote ferroptosis by PPARα-mediated lipid remodeling.Divya Venkatesh et al.Genes & development, 34(7-8), 526-543 (2020-02-23) Genetic ablation of solute carrier family 7a3a leads to hepatic steatosis in zebrafish during fasting.Qilin Gu et al.Hepatology (Baltimore, Md.), 60(6), 1929-1941 (2014-08-19) Tumor necrosis factor α stimulates endogenous apolipoprotein A-I expression and secretion by human monocytes and macrophages: role of MAP-kinases, NF-κB, and nuclear receptors PPARα and LXRs.Vladimir S Shavva et al.Molecular and cellular biochemistry, 448(1-2), 211-223 (2018-02-15) PPARα and PPARγ regulate the nucleoside transporter hENT1.Trinidad D Montero et al.Biochemical and biophysical research communications, 419(2), 405-411 (2012-02-22) Fenofibrate prevents the disruption of the outer blood retinal barrier through downregulation of NF-κB activity.Marta Garcia-Ramírez et al.Acta diabetologica, 53(1), 109-118 (2015-05-06) Organotypic modeling of human keratinocyte response to peroxisome proliferators.Carmen Zhang et al.Cells, tissues, organs, 196(5), 431-441 (2012-06-09) Cytokine production by infrapatellar fat pad can be stimulated by interleukin 1β and inhibited by peroxisome proliferator activated receptor α agonist.Stefan Clockaerts et al.Annals of the rheumatic diseases, 71(6), 1012-1018 (2012-02-07) Co-treatment with retinyl retinoate and a PPARα agonist reduces retinoid dermatitis.Bora Kim et al.International journal of dermatology, 51(6), 733-741 (2012-05-23) PPARα regulates cholinergic-driven activity of midbrain dopamine neurons via a novel mechanism involving α7 nicotinic acetylcholine receptors.Miriam Melis et al.The Journal of neuroscience : the official journal of the Society for Neuroscience, 33(14), 6203-6211 (2013-04-05) Nuclear receptors agonists exert opposing effects on the inflammation dependent survival of breast cancer stem cells.A Papi et al.Cell death and differentiation, 19(7), 1208-1219 (2012-01-21) Muscle lipogenesis balances insulin sensitivity and strength through calcium signaling.Katsuhiko Funai et al.The Journal of clinical investigation, 123(3), 1229-1240 (2013-02-05) Wy14643 improves vascular function in the aorta of the spontaneously hypertensive rat mainly by activating peroxisome proliferator-activated receptors alpha.Chen Qu et al.European journal of pharmacology, 696(1-3), 101-110 (2012-10-02) Fenofibrate down-regulates renal OCT2-mediated organic cation transport via PPARα-independent pathways.Nithi Asavapanumas et al.Drug metabolism and pharmacokinetics, 27(5), 513-519 (2012-04-05) Activation of PPARα by Wy-14643 ameliorates systemic lipopolysaccharide-induced acute lung injury.Seong Ho Yoo et al.Biochemical and biophysical research communications, 436(3), 366-371 (2013-06-04) Peroxisome proliferator-activated receptor-alpha agonists repress expression of thrombin-activatable fibrinolysis inhibitor by decreasing transcript stability.Yutaka Masuda et al.Thrombosis and haemostasis, 108(1), 74-85 (2012-04-27)

备注