
2'-Chloroacetanilide | CAS:533-17-5
2'-Chloroacetanilide
- 名称:N-(2-氯苯基)乙酰胺 | 2'-Chloroacetanilide
- CAS号:533-17-5
- 别名:N-(2-Chlorophenyl)acetamide
- 分子式:C8H8ClNO
- 分子量:169.61
- EINESC号:208-555-2
产品描述
物理化学性质
熔点 | 85-88 ºC |
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水溶性 | 几乎不溶 |
安全数据
危险品标志 | Xi |
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危险类别码 | R36/37/38 |
安全说明书 | S26;S37/39 |
SDS
来源 | SDS样本 |
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没有数据 | 没有数据 |
产品合成路线
名称 | CAS号 |
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BJOG Editors' Choice.Pierre Martin-Hirsch et al.BJOG : an international journal of obstetrics and gynaecology, 120(3), i-ii (2013-01-16)
Misoprostol modulates cytokine expression through a cAMP pathway: Potential therapeutic implication for liver disease.Leila Gobejishvili et al.Clinical immunology (Orlando, Fla.), 161(2), 291-299 (2015-09-27)
Effects of vaginal versus oral misoprostol to terminate second-trimester pregnancy.S H Yazdani et al.Clinical and experimental obstetrics & gynecology, 39(4), 529-531 (2013-03-01)
Decreased RORC-dependent silencing of prostaglandin receptor EP2 induces autoimmune Th17 cells.David M Kofler et al.The Journal of clinical investigation, 124(6), 2513-2522 (2014-05-09)
[Assessment of efficacy and safety of medical treatment of non-viable first trimester pregnancy].Aneta Zwierzchowska et al.Ginekologia polska, 83(10), 760-765 (2013-02-07)
[The use of prostaglandin F2alpha (Prostin 15M) for terminationof second trimester pregnancy].S Bojinova et al.Akusherstvo i ginekologiia, 52(2), 53-55 (2013-07-03)
Cervical ripening prior to hysteroscopy: is the application of misoprostol useful?S Arena et al.Minerva ginecologica, 63(5), 439-448 (2011-09-20)
Prophylactic compared with therapeutic ibuprofen analgesia in first-trimester medical abortion: a randomized controlled trial.Elizabeth G Raymond et al.Obstetrics and gynecology, 122(3), 558-564 (2013-08-08)
Introduction of misoprostol for the treatment of incomplete abortion beyond 12 weeks of pregnancy in Benin.Sosthène Adisso et al.International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics, 126 Suppl 1, S36-S39 (2014-05-08)
Evaluating misoprostol content in pregnant women with hourly oral administration during labor induction by microElution solid phase extraction combined with liquid chromatography tandem mass spectrometry.Cheng-Han Hung et al.Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 1000, 176-180 (2015-08-08)
Misoprostol for miscarriages. The Medical letter on drugs and therapeutics, 55(1411), 19-20 (2013-03-08)
Termination of second-trimester pregnancy by mifepristone combined with misoprostol versus intra-amniotic injection of ethacridine lactate (Rivanol®): a systematic review of Chinese trials.Shu-Ping Hou et al.Contraception, 84(3), 214-223 (2011-08-17)
Sequential use of mifepristone and misoprostol in treatment of early pregnancy failure appears more effective than misoprostol alone: a retrospective study.Joyce van den Berg et al.European journal of obstetrics, gynecology, and reproductive biology, 183, 16-19 (2014-12-03)
Efficacy and acceptability of a mifepristone-misoprostol combined regimen for early induced abortion among women in Mexico City.Melanie Peña et al.International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics, 127(1), 82-85 (2014-06-25)
Randomized clinical trial between hourly titrated oral misoprostol and vaginal dinoprostone for induction of labor.Abdulrahim A Rouzi et al.American journal of obstetrics and gynecology, 210(1), 56-56 (2013-09-04)
Misoprostol for incomplete first trimester miscarriage.Nathan Hitzeman et al.American family physician, 89(7), 523-524 (2014-04-04)
Sequential use of mifepristone and misoprostol in treatment of early pregnancy failure appears more effective than misoprostol alone: a retrospective study.Joyce van den Berg et al.European journal of obstetrics, gynecology, and reproductive biology, 183, 16-19 (2014-12-03)
Misoprostol modulates cytokine expression through a cAMP pathway: Potential therapeutic implication for liver disease.Leila Gobejishvili et al.Clinical immunology (Orlando, Fla.), 161(2), 291-299 (2015-09-27)
Cervical ripening prior to hysteroscopy: is the application of misoprostol useful?S Arena et al.Minerva ginecologica, 63(5), 439-448 (2011-09-20)
Prophylactic compared with therapeutic ibuprofen analgesia in first-trimester medical abortion: a randomized controlled trial.Elizabeth G Raymond et al.Obstetrics and gynecology, 122(3), 558-564 (2013-08-08)
Effect of a single preoperative dose of sublingual misoprostol on intraoperative blood loss during total abdominal hysterectomy.Jhuma Biswas et al.International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics, 122(3), 244-247 (2013-06-27)
Prostaglandins are essential for cervical ripening in LPS-mediated preterm birth but not term or antiprogestin-driven preterm ripening.Brenda C Timmons et al.Endocrinology, 155(1), 287-298 (2013-11-06)
Continuation of pregnancy after first-trimester exposure to mifepristone: an observational prospective study.N Bernard et al.BJOG : an international journal of obstetrics and gynaecology, 120(5), 568-574 (2013-01-26)
Medical treatments for incomplete miscarriage.James P Neilson et al.The Cochrane database of systematic reviews, 3(3), CD007223-CD007223 (2013-04-02)
Misoprostol prior to hysteroscopy in premenopausal and post-menopausal women. A systematic review and meta-analysis.N P Polyzos et al.Human reproduction update, 18(4), 393-404 (2012-05-01)
Oral misoprostol versus oxytocin in the management of third stage of labour.Saima Aziz et al.JPMA. The Journal of the Pakistan Medical Association, 64(4), 428-432 (2014-05-29)
A report from #BlueJC: should oral misoprostol be used in home births in low-resource countries?J Hussein et al.BJOG : an international journal of obstetrics and gynaecology, 120(9), 1156-1157 (2013-07-11)
Sublingual versus vaginal misoprostol for cervical dilatation 1 or 3 h prior to surgical abortion: a double-blinded RCT.Ingrid Sääv et al.Human reproduction (Oxford, England), 30(6), 1314-1322 (2015-04-04)
Sodium caprate-induced increases in intestinal permeability and epithelial damage are prevented by misoprostol.David J Brayden et al.European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V, 94, 194-206 (2015-06-01)
A trial comparing the use of rectal misoprostol plus perivascular vasopressin with perivascular vasopressin alone to decrease myometrial bleeding at the time of abdominal myomectomy.Sharifa Frederick et al.Fertility and sterility, 100(4), 1044-1049 (2013-07-24)
Is the protocol for induction of labor in singletons applicable to twin gestations?Michael D Wolfe et al.The Journal of reproductive medicine, 58(3-4), 137-142 (2013-04-02)
Sodium caprate-induced increases in intestinal permeability and epithelial damage are prevented by misoprostol.David J Brayden et al.European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V, 94, 194-206 (2015-06-01)
A trial comparing the use of rectal misoprostol plus perivascular vasopressin with perivascular vasopressin alone to decrease myometrial bleeding at the time of abdominal myomectomy.Sharifa Frederick et al.Fertility and sterility, 100(4), 1044-1049 (2013-07-24)
Sublingual versus vaginal misoprostol for cervical dilatation 1 or 3 h prior to surgical abortion: a double-blinded RCT.Ingrid Sääv et al.Human reproduction (Oxford, England), 30(6), 1314-1322 (2015-04-04)
Implementation of misoprostol for postabortion care in Kenya and Uganda: a qualitative evaluation.Joachim Osur et al.Global health action, 6, 1-11 (2013-04-27)
Production of prostaglandin E2 induced by cigarette smoke modulates tissue factor expression and activity in endothelial cells.Patrizia Amadio et al.FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 29(9), 4001-4010 (2015-06-13)
Termination of second-trimester pregnancy by mifepristone combined with misoprostol versus intra-amniotic injection of ethacridine lactate (Rivanol®): a systematic review of Chinese trials.Shu-Ping Hou et al.Contraception, 84(3), 214-223 (2011-08-17)
Should oral misoprostol be used to prevent postpartum haemorrhage in home-birth settings in low-resource countries? A systematic review of the evidence.V A Hundley et al.BJOG : an international journal of obstetrics and gynaecology, 120(3), 277-285 (2012-11-30)
Progress of labor in women induced with misoprostol versus the Foley catheter.Methodius G Tuuli et al.American journal of obstetrics and gynecology, 209(3), 237-237 (2013-05-11)
Effect of misoprostol versus oxytocin during caesarean section: a systematic review and meta-analysis.J Hua et al.BJOG : an international journal of obstetrics and gynaecology, 120(5), 531-540 (2013-01-22)
Should we ban labor induction?Michel Odent Midwifery today with international midwife, (107)(107), 22-23 (2013-10-19)
Misoprostol for labor induction in the second trimester in a woman with previous three cesarean deliveries and an intrauterine death of an anencephaly.A A Rouzi Clinical and experimental obstetrics & gynecology, 40(1), 157-158 (2013-06-04)
New hope: community-based misoprostol use to prevent postpartum haemorrhage.Ndola Prata et al.Health policy and planning, 28(4), 339-346 (2012-08-11)
Combination of Foley bulb and vaginal misoprostol compared with vaginal misoprostol alone for cervical ripening and labor induction: a randomized controlled trial.Jeanine F Carbone et al.Obstetrics and gynecology, 121(2 Pt 1), 247-252 (2013-01-11)
The management and outcomes of placenta accreta, increta, and percreta in the UK: a population-based descriptive study.K E Fitzpatrick et al.BJOG : an international journal of obstetrics and gynaecology, 121(1), 62-70 (2013-08-09)
Randomized clinical trial between hourly titrated oral misoprostol and vaginal dinoprostone for induction of labor.Abdulrahim A Rouzi et al.American journal of obstetrics and gynecology, 210(1), 56-56 (2013-09-04)
Nurse versus physician-provision of early medical abortion in Mexico: a randomized controlled non-inferiority trial.Claudia Diaz Olavarrieta et al.Bulletin of the World Health Organization, 93(4), 249-258 (2015-08-01)
Misoprostol for incomplete first trimester miscarriage.Nathan Hitzeman et al.American family physician, 89(7), 523-524 (2014-04-04)
Mucosal protective agents prevent exacerbation of NSAID-induced small intestinal lesions caused by antisecretory drugs in rats.Hiroshi Satoh et al.The Journal of pharmacology and experimental therapeutics, 348(2), 227-235 (2013-11-21)
Mifepristone-misoprostol dosing interval and effect on induction abortion times: a systematic review.Kate A Shaw et al.Obstetrics and gynecology, 121(6), 1335-1347 (2013-07-03)
Postpartum hemorrhage in the developed world: whither misoprostol?Karen J Gibbins et al.American journal of obstetrics and gynecology, 208(3), 181-183 (2012-08-21)
Novel mechanisms and signaling pathways of esophageal ulcer healing: the role of prostaglandin EP2 receptors, cAMP, and pCREB.Amrita Ahluwalia et al.American journal of physiology. Gastrointestinal and liver physiology, 307(6), G602-G610 (2014-07-26)
Experiences engaging community health workers to provide maternal and newborn health services: implementation of four programs.Jaime Haver et al.International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics, 130 Suppl 2, S32-S39 (2015-06-28)
Advance misoprostol distribution for preventing and treating postpartum haemorrhage.Olufemi T Oladapo et al.The Cochrane database of systematic reviews, 2(2), CD009336-CD009336 (2012-02-18)
Misoprostol in operative hysteroscopy: a systematic review and meta-analysis.Amanda Selk et al.Obstetrics and gynecology, 118(4), 941-949 (2011-09-22)
Reviewer's commentary on 'Continuation of pregnancy after first-trimester exposure to mifepristone: an observational prospective study'.S Cameron BJOG : an international journal of obstetrics and gynaecology, 120(5), 575-575 (2013-04-20)
The role of food for the formation and prevention of gastrointestinal lesions induced by aspirin in cats.Hiroshi Satoh et al.Digestive diseases and sciences, 58(10), 2840-2849 (2013-06-15)
Hysteroscopic Myomectomy of Large Submucous Myomas in a 1-Step Procedure Using Multiple Slicing Sessions Technique.Mohamed Zayed et al.Journal of minimally invasive gynecology, 22(7), 1196-1202 (2015-06-21)
Oral misoprostol in the prevention of uterine bleeding after surgical evacuation of first trimester abortion: a comparative study of three uterotonic agents.T M Aramide et al.Nigerian journal of clinical practice, 17(1), 10-13 (2013-12-12)
Sublingual misoprostol as an adjunct to oxytocin during cesarean delivery in women at risk of postpartum hemorrhage.Picklu Chaudhuri et al.International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics, 128(1), 48-52 (2014-10-04)
Prevention of NSAID-induced gastric ulcer with misoprostol: multicentre, double-blind, placebo-controlled trial.D Y Graham et al.Lancet (London, England), 2(8623), 1277-1280 (1988-12-03)
Misoprostol for postpartum hemorrhage prevention at home birth: an integrative review of global implementation experience to date.Jeffrey Michael Smith et al.BMC pregnancy and childbirth, 13, 44-44 (2013-02-21)
Misoprostol to reduce intraoperative and postoperative hemorrhage during cesarean delivery: a systematic review and metaanalysis.Agustín Conde-Agudelo et al.American journal of obstetrics and gynecology, 209(1), 40-40 (2013-03-20)
Buccal misoprostol compared with synthetic osmotic cervical dilator before surgical abortion: a randomized controlled trial.Deborah Bartz et al.Obstetrics and gynecology, 122(1), 57-63 (2013-06-08)
Misoprostol versus Foley catheter insertion for induction of labor in pregnancies affected by fetal growth restriction.Pearlin R Chavakula et al.International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics, 129(2), 152-155 (2015-02-11)
Postpartum misoprostol for preventing maternal mortality and morbidity.G Justus Hofmeyr et al.The Cochrane database of systematic reviews, 7(7), CD008982-CD008982 (2013-07-17)
Cytotec and the FDA.Ina May Gaskin Midwifery today with international midwife, (107)(107), 8-14 (2013-10-19)
[Developmental toxicity of misoprostol: an update].María Fernanda Cavieres Revista medica de Chile, 139(4), 516-523 (2011-09-01)
Personalized Mapping of Drug Metabolism by the Human Gut Microbiome.Bahar Javdan et al.Cell, 181(7), 1661-1679 (2020-06-12)
A randomized controlled trial on the value of misoprostol for the treatment of retained placenta in a low-resource setting.Heleen J van Beekhuizen et al.International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics, 122(3), 234-237 (2013-06-25)
Reply: To PMID 23659988.Methodius G Tuuli et al.American journal of obstetrics and gynecology, 210(1), 91-92 (2013-08-27)
Evolving therapeutic strategies to improve nonsteroidal anti-inflammatory drug safety.Bill H McCarberg et al.American journal of therapeutics, 22(6), e167-e178 (2014-09-25)
New global guidance supports community and lay health workers in postpartum hemorrhage prevention.Clara Ladi Ejembi et al.International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics, 122(3), 187-189 (2013-06-26)
Misoprostol-induced termination of second-trimester pregnancy in women with a history of cesarean section: a retrospective analysis of 56 cases.Abdulkadir Turgut et al.Ginekologia polska, 84(4), 277-280 (2013-05-25)
Elevated expression levels of matrix metalloproteinase-9 in placental villi and tissue inhibitor of metalloproteinase-2 in decidua are associated with prolonged bleeding after mifepristone-misoprostol medical abortion.Yaling Zhuang et al.Fertility and sterility, 101(1), 166-171 (2013-11-12)
Rectal misoprostol for myomectomy: A randomised placebo-controlled study.Mohamed Abdel-Hafeez et al.The Australian & New Zealand journal of obstetrics & gynaecology, 55(4), 363-368 (2015-07-16)
Mifepristone followed by misoprostol or oxytocin for second-trimester abortion: a randomized controlled trial.Matan Elami-Suzin et al.Obstetrics and gynecology, 122(4), 815-820 (2013-10-03)
A comparison of rectal misoprostol and intravenous oxytocin on hemorrhage and homeostatic changes during cesarean section.Mohammad Reza Fazel et al.Middle East journal of anaesthesiology, 22(1), 41-46 (2013-07-10)
Randomization of two dosing regimens of vaginal misoprostol for cervical ripening and labor induction in a low resource setting.A A Adeniyi et al.Nigerian journal of clinical practice, 17(3), 287-291 (2014-04-10)
Complete chorioamniotic separation and persistence of a yolk sac associated with triploidy.Onur Erol et al.Journal of obstetrics and gynaecology Canada : JOGC = Journal d'obstetrique et gynecologie du Canada : JOGC, 35(10), 914-916 (2013-10-30)
Methods of term labour induction for women with a previous caesarean section.Marta Jozwiak et al.The Cochrane database of systematic reviews, 3(3), CD009792-CD009792 (2013-04-02)
A double-blind randomized controlled trial of mifepristone or placebo before buccal misoprostol for abortion at 14-21 weeks of pregnancy.Rasha Dabash et al.International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics, 130(1), 40-44 (2015-04-22)
Titrated oral misoprostol for augmenting labour to improve maternal and neonatal outcomes.Joshua P Vogel et al.The Cochrane database of systematic reviews, 9(9), CD010648-CD010648 (2013-09-24)
Misoprostol for the prevention and treatment of postpartum hemorrhage.Wendy R Sheldon et al.Expert opinion on investigational drugs, 21(2), 235-250 (2012-01-12)
The use of prophylactic gastroprotective therapy in patients with nonsteroidal anti-inflammatory drug- and aspirin-associated ulcer bleeding: a cross-sectional study.C W Ho et al.Alimentary pharmacology & therapeutics, 37(8), 819-824 (2013-02-26)
How effective are the components of active management of the third stage of labor?Wendy R Sheldon et al.BMC pregnancy and childbirth, 13, 46-46 (2013-02-26)
Postabortion care in Pakistan.Zeba Sathar et al.Issues in brief (Alan Guttmacher Institute), (4)(4), 1-8 (2013-09-07)
PGE2 receptor agonist misoprostol protects brain against intracerebral hemorrhage in mice.He Wu et al.Neurobiology of aging, 36(3), 1439-1450 (2015-01-28)
Sequential use of double-balloon catheter and oral misoprostol versus oral misoprostol alone for induction of labour at term (CRBplus trial): a multicentre, open-label randomised controlled trial.S Kehl et al.BJOG : an international journal of obstetrics and gynaecology, 122(1), 129-136 (2014-10-21)
New anomalies due to methotrexate and misoprostol exposure in early pregnancy.Kate MacDonald et al.International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics, 122(3), 267-268 (2013-06-25)
["Off label" use of some medicinal products. Part II. "Off label" use of misoprostol].M Sirakov Akusherstvo i ginekologiia, 51(3), 50-54 (2012-12-15)
[Misoprostol off label essential for women's health].Kristina Gemzell Danielsson Lakartidningen, 110(46), 2045-2046 (2014-01-02)
Anaphylaxis to buccal misoprostol for labor induction.Corina Schoen et al.Obstetrics and gynecology, 124(2 Pt 2 Suppl 1), 466-468 (2014-07-09)
Medical abortion with mifepristone and home administration of misoprostol up to 63 days' gestation.Mette Løkeland et al.Acta obstetricia et gynecologica Scandinavica, 93(7), 647-653 (2014-04-29)
Enterobacteria-secreted particles induce production of exosome-like S1P-containing particles by intestinal epithelium to drive Th17-mediated tumorigenesis.Zhongbin Deng et al.Nature communications, 6, 6956-6956 (2015-04-25)
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