密度	1.788±0.06 g/cm3 (20 º

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Restoring basal planes of graphene oxides for highly efficient loading and delivery of β-lapachone.Xin Ting Zheng et al.Molecular pharmaceutics, 9(3), 615-621 (2012-01-24) Effects of β-lapachone, a new anticancer candidate, on cytochrome P450-mediated drug metabolism.In Sook Kim et al.Cancer chemotherapy and pharmacology, 72(3), 699-702 (2013-07-24) The encapsulation of β-lapachone in 2-hydroxypropyl-β-cyclodextrin inclusion complex into liposomes: a physicochemical evaluation and molecular modeling approach.Isabella M F Cavalcanti et al.European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences, 44(3), 332-340 (2011-09-06) Effects of β-lapachone on the production of Th1 and Th2 cytokines in C57BL/6 mice.Myungwon Choi et al.Journal of environmental pathology, toxicology and oncology : official organ of the International Society for Environmental Toxicology and Cancer, 31(2), 87-94 (2012-12-12) Light effect on the stability of β-lapachone in solution: pathways and kinetics of degradation.Marcílio S S Cunha-Filho et al.The Journal of pharmacy and pharmacology, 63(9), 1156-1160 (2011-08-11) β-Lapachone ameliorization of experimental autoimmune encephalomyelitis.Jihong Xu et al.Journal of neuroimmunology, 254(1-2), 46-54 (2012-09-27) beta-Lapachone, a novel DNA topoisomerase I inhibitor with a mode of action different from camptothecin.C J Li et al.The Journal of biological chemistry, 268(30), 22463-22468 (1993-10-25) Smart design of intratumoral thermosensitive β-lapachone hydrogels by Artificial Neural Networks.P Díaz-Rodríguez et al.International journal of pharmaceutics, 433(1-2), 112-118 (2012-05-23) β-lapachone significantly increases the effect of ionizing radiation to cause mitochondrial apoptosis via JNK activation in cancer cells.Moon-Taek Park et al.PloS one, 6(10), e25976-e25976 (2011-10-15) NAD(P)H:quinone oxidoreductase 1 (NQO1) in the sensitivity and resistance to antitumor quinones.David Siegel et al.Biochemical pharmacology, 83(8), 1033-1040 (2012-01-03) Temperature-sensitive gels for intratumoral delivery of β-lapachone: effect of cyclodextrins and ethanol.Marcilio S S Cunha-Filho et al.TheScientificWorldJournal, 2012, 126723-126723 (2012-05-26) Preclinical genotoxicology of nor-β-lapachone in human cultured lymphocytes and Chinese hamster lung fibroblasts.Bruno C Cavalcanti et al.Chemical research in toxicology, 24(9), 1560-1574 (2011-08-13) Prevention of salt-induced renal injury by activation of NAD(P)H:quinone oxidoreductase 1, associated with NADPH oxidase.Yong-Hoon Kim et al.Free radical biology & medicine, 52(5), 880-888 (2012-01-10) Beta-lapachone-mediated apoptosis in human promyelocytic leukemia (HL-60) and human prostate cancer cells: a p53-independent response.S M Planchon et al.Cancer research, 55(17), 3706-3711 (1995-09-01) No role of homologous recombination in dealing with β-lapachone cytotoxicity in yeast.Oliver Quevedo et al.Chemical research in toxicology, 24(12), 2106-2108 (2011-11-19) Beta-lapachone, a modulator of NAD metabolism, prevents health declines in aged mice.Jeong-sook Lee et al.PloS one, 7(10), e47122-e47122 (2012-10-17) [Cytotoxicity of beta-lapachone, an naphthoquinone with possible therapeutic use].M Dubin et al.Medicina, 61(3), 343-350 (2001-07-28) An NQO1 substrate with potent antitumor activity that selectively kills by PARP1-induced programmed necrosis.Xiumei Huang et al.Cancer research, 72(12), 3038-3047 (2012-04-26) Peroxiredoxin 1 knockdown potentiates β-lapachone cytotoxicity through modulation of reactive oxygen species and mitogen-activated protein kinase signals.Tiantian He et al.Carcinogenesis, 34(4), 760-769 (2012-12-15) Redox cycling of beta-lapachone and structural analogues in microsomal and cytosol liver preparations.Silvia Fernández Villamil et al.Methods in enzymology, 378, 67-87 (2004-03-25) Inhibition of transcription by dactinomycin reveals a new characteristic of immunogenic cell stress.Juliette Humeau et al.EMBO molecular medicine, 12(5), e11622-e11622 (2020-04-24) Cancer therapy with beta-lapachone.Arthur B Pardee et al.Current cancer drug targets, 2(3), 227-242 (2002-08-22) beta-Lapachone-induced apoptosis is associated with activation of caspase-3 and inactivation of NF-kappaB in human colon cancer HCT-116 cells.Byung Tae Choi et al.Anti-cancer drugs, 14(10), 845-850 (2003-11-05) β-lapachone accelerates the recovery of burn-wound skin.Shih-Chen Fu et al.Histology and histopathology, 26(7), 905-914 (2011-06-02) Endoplasmic reticulum stress-induced JNK activation is a critical event leading to mitochondria-mediated cell death caused by β-lapachone treatment.Hyemi Lee et al.PloS one, 6(6), e21533-e21533 (2011-07-09) Anti-inflammatory and anti-arthritic activities of 3,4-dihydro-2,2-dimethyl-2H-naphthol[1,2-b]pyran-5,6-dione (β-lapachone).Marília Maria Sitônio et al.Inflammation research : official journal of the European Histamine Research Society ... [et al.], 62(1), 107-113 (2012-10-12) β-Lapachone analogs with enhanced antiproliferative activity.Carla Ríos-Luci et al.European journal of medicinal chemistry, 53, 264-274 (2012-05-09) Synthesis of biologically active (-)-dehydroiso-β-lapachone and the determination of its absolute configuration.Tetsutaro Kimachi et al.Chemical & pharmaceutical bulletin, 59(6), 753-756 (2011-06-02) Screening of anti-cancer agent using zebrafish: comparison with the MTT assay.Yigen Li et al.Biochemical and biophysical research communications, 422(1), 85-90 (2012-05-09) NQO1 is a determinant for cellular sensitivity to anti-tumor agent Napabucasin.Gaigai Guo et al.American journal of cancer research, 10(5), 1442-1454 (2020-06-09) Superparamagnetic iron oxide nanoparticles: amplifying ROS stress to improve anticancer drug efficacy.Gang Huang et al.Theranostics, 3(2), 116-126 (2013-02-21) Cellular DNA Topoisomerases Are Required for the Synthesis of Hepatitis B Virus Covalently Closed Circular DNA.Muhammad Sheraz et al.Journal of virology, 93(11) (2019-03-15) Ultrastructural analysis of β-lapachone-induced surface membrane damage in male adult Schistosoma mansoni BH strain worms.André de Lima Aires et al.Experimental parasitology, 142, 83-90 (2014-04-29) Mechanistic studies of cancer cell mitochondria- and NQO1-mediated redox activation of beta-lapachone, a potentially novel anticancer agent.Jason Z Li et al.Toxicology and applied pharmacology, 281(3), 285-293 (2014-12-03) Photosensitization mechanisms of triplet excited state beta-lapachone. A density functional theory study.Liang Shen Natural product communications, 6(11), 1677-1678 (2012-01-10) β-Lapachone induces heart morphogenetic and functional defects by promoting the death of erythrocytes and the endocardium in zebrafish embryos.Yi-Ting Wu et al.Journal of biomedical science, 18, 70-70 (2011-09-23) Synthesis and anti-inflammatory evaluations of β-lapachone derivatives.Chih-Hua Tseng et al.Bioorganic & medicinal chemistry, 21(2), 523-531 (2012-12-13)

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