Salicylanilide | CAS:87-17-2
            
            Salicylanilide
            - 名称:水杨酰苯胺; N-水杨酰苯胺; N-苯基水杨酰胺 | Salicylanilide
 - CAS号:87-17-2
 - 别名:2-Hydroxybenzanilide; 2-Hydroxy-N-phenylbenzamide; N-Phenylsalicylamide
 - 分子式:C13H11NO2
 - 分子量:213.23
 - EINESC号:201-727-8
 
产品描述
物理化学性质
| 熔点 | 136-138 ºC | 
|---|---|
| 水溶性 | 微溶 | 
安全数据
| 危险品标志 | Xi | 
|---|---|
| 危险类别码 | R36/37/38 | 
| 安全说明书 | S26;S37/39 | 
SDS
| 来源 | SDS样本 | 
|---|---|
| 没有数据 | 没有数据 | 
产品合成路线
                | 名称 | CAS号 | 
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                                        Intravascular plasma disposition and salivary secretion of closantel and rafoxanide in sheep.G E Swan et al.Journal of the South African Veterinary Association, 70(2), 75-79 (2000-06-16)
                                        Quality control in generic anthelmintics: is it adequate?J A van Wyk et al.Veterinary parasitology, 72(2), 157-165 (1997-12-24)
                                        Anthelmintic resistance in South Africa: surveys indicate an extremely serious situation in sheep and goat farming.J A Van Wyk et al.The Onderstepoort journal of veterinary research, 66(4), 273-284 (2000-02-26)
                                        Screening of closantel and rafoxanide in animal muscles by HPLC with fluorescence detection and confirmation using MS.Hoi-sze Yeung et al.Journal of separation science, 33(2), 206-211 (2009-12-10)
                                         Veterinary Pharmacology and Therapeutics (2017)
                                        Rafoxanide and Closantel Inhibit SPAK and OSR1 Kinases by Binding to a Highly Conserved Allosteric Site on Their C-terminal Domains.Mubarak A AlAmri et al.ChemMedChem, 12(9), 639-645 (2017-04-04)
                                        Multiple anthelmintic resistance on a goat farm in Kenya.R M Waruiru et al.Veterinary parasitology, 75(2-3), 191-197 (1998-06-24)
                                        Antitumor effects of rafoxanide in diffuse large B cell lymphoma via the PTEN/PI3K/Akt and JNK/c-Jun pathways.Wan He et al.Life sciences, 243, 117249-117249 (2020-01-12)
                                        Determination of closantel and rafoxanide in animal tissues by online anionic mixed-mode solid-phase extraction followed by isotope dilution liquid chromatography tandem mass spectrometry.Shirley Sau Ling Lai et al.Journal of separation science, 34(12), 1366-1374 (2011-05-12)
                                        Discovery of rafoxanide as a dual CDK4/6 inhibitor for the treatment of skin cancer.Xinan Shi et al.Oncology reports, 40(3), 1592-1600 (2018-06-30)
                                        Avermectin inhibition of larval development in Haemonchus contortus--effects of ivermectin resistance.J H Gill et al.International journal for parasitology, 25(4), 463-470 (1995-04-01)
                                        The Hymenolepis diminuta-golden hamster (Mesocricetus auratus) model for the evaluation of gastrointestinal anticestode activity.D A Ostlind et al.The Journal of parasitology, 90(4), 898-899 (2004-09-11)
                                        The efficacy of closantel and rafoxanide against fenbendazole- and levamisole-resistant Haemonchus contortus in small ruminants.R M Waruiru Veterinary research communications, 21(7), 493-497 (1997-11-05)
                                        Quantitative analysis of closantel and rafoxanide in bovine and ovine muscles by high-performance liquid chromatography with fluorescence detection.Hoi-Sze Yeung et al.Journal of AOAC International, 93(5), 1672-1677 (2010-12-15)
                                        Field trial on comparative efficacy of four fasciolicides against natural liver fluke infection in cattle.Bülent Elitok et al.Veterinary parasitology, 135(3-4), 279-285 (2005-11-18)
                                        Development and Optimisation of a Multiresidue Method for the Determination of 40 Anthelmintic Compounds in Environmental Water Samples by Solid Phase Extraction (SPE) with LC-MS/MS Detection.Damien Mooney et al.Molecules (Basel, Switzerland), 24(10) (2019-05-28)
                                        A dual anthelmintic treatment strategic scheme for the control of fasciolosis in dairy sheep farms.Giuseppe Cringoli et al.Parasitology research, 99(6), 700-705 (2006-06-02)
                                        Effect of three anthelmentics on disposition kinetics of florfenicol in goats.M Atef et al.Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 48(12), 3340-3344 (2010-09-25)
                                        Rafoxanide Induces Immunogenic Death of Colorectal Cancer Cells.Antonio Di Grazia et al.Cancers, 12(5) (2020-05-28)
                                        Rafoxanide, an organohalogen drug, triggers apoptosis and cell cycle arrest in multiple myeloma by enhancing DNA damage responses and suppressing the p38 MAPK pathway.Wenqin Xiao et al.Cancer letters, 444, 45-59 (2018-12-26)
                                        Comparative efficacy of different anthelmintics against fenbendazole-resistant nematodes of pashmina goats.H Ram et al.Veterinary research communications, 31(6), 719-723 (2007-02-20)
                                        Anthelmintic resistance of nematodes in communally grazed goats in a semi-arid area of South Africa.F R Bakunzi Journal of the South African Veterinary Association, 74(3), 82-83 (2004-03-20)
                                        Anthelmintic resistance of trichostrongylids in sheep in the highveld of Zimbabwe.J H Boersema et al.Veterinary parasitology, 68(4), 383-388 (1997-03-01)
                                        The Photosensitising Clinical Agent Verteporfin Is an Inhibitor of SPAK and OSR1 Kinases.Mubarak A AlAmri et al.Chembiochem : a European journal of chemical biology, 19(19), 2072-2080 (2018-07-13)
                                        Determination of rafoxanide in plasma using high performance liquid chromatography (HPLC) and in tissue using HPLC-thermospray mass spectrometryBlanchflower J W, et al. Journal of Liquid Chromatography, 13(8), 1595-1609 (1990)
                                        Stability and partitioning of closantel and rafoxanide in ruminal fluid of sheep.G E Swan et al.The Onderstepoort journal of veterinary research, 67(2), 97-103 (2000-10-12)
                                        Differences in the oral bioavailability of three rafoxanide formulations in sheep.G E Swan et al.Journal of the South African Veterinary Association, 66(4), 197-201 (1995-12-01)
                                        An improved thyroid hormone reporter assay to determine the thyroid hormone-like activity of amiodarone, bithionol, closantel and rafoxanide.Kana Matsubara et al.Toxicology letters, 208(1), 30-35 (2011-10-22)
                                        Comparative pharmacokinetics of ivermectin alone and a novel formulation of ivermectin and rafoxanide in calves and sheep.H A El-Banna et al.Parasitology research, 102(6), 1337-1342 (2008-02-26)
                                        Anthelmintic resistance on an organized sheep farm in India.C P Swarnkar et al.Tropical animal health and production, 33(4), 305-312 (2001-07-28)
                                        Glutathione S-transferases as markers of salicylanilide resistance in isolates of Fasciola hepatica.C M Miller et al.International journal for parasitology, 24(4), 533-542 (1994-07-01)
                                        Relative bioavailability of rafoxanide following intraruminal and intra-abomasal administration in sheep.G E Swan et al.Journal of the South African Veterinary Association, 70(2), 71-74 (2000-06-16)
                                    
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            Products protected by valid patents are not offered for sale in countries where the sale of such products constitutes a patent infringement and its liability is at buyer's risk.
Products currently covered by valid US Patents are offered for R&D use in accordance with 35 USC 271 +A13(1).
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