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Uncarine D | CAS:4697-68-1
Uncarine D
  • 名称:恩卡林碱 D | Uncarine D
  • CAS号:4697-68-1
  • 别名:Uncarin D; NSC 113094; 19-Methyl-2-oxo-formosanan-16-carboxylic acid methyl ester
  • 分子式:C21H24N2O4
  • 分子量:368.43
  • EINESC号:

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物理化学性质

密度 1.33

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Ebola drug trials lurch ahead.Kai Kupferschmidt et al.Science (New York, N.Y.), 347(6223), 701-702 (2015-02-14) 5-Formylcytosine alters the structure of the DNA double helix.Eun-Ang Raiber et al.Nature structural & molecular biology, 22(1), 44-49 (2014-12-17) Biochemical basis of immunological and retroviral responses to DNA-targeted cytosine deamination by activation-induced cytidine deaminase and APOBEC3G.Linda Chelico et al.The Journal of biological chemistry, 284(41), 27761-27765 (2009-08-18) From trans-methylation to cytosine methylation: evolution of the methylation hypothesis of schizophrenia.Dennis R Grayson et al.Epigenetics, 4(3), 144-149 (2009-04-28) Inflammation-mediated cytosine damage: a mechanistic link between inflammation and the epigenetic alterations in human cancers.Victoria Valinluck et al.Cancer research, 67(12), 5583-5586 (2007-06-19) Aberrant cytosine hydroxymethylation in hematologic malignancies.Mamiko Sakata-Yanagimoto et al.[Rinsho ketsueki] The Japanese journal of clinical hematology, 54(5), 423-430 (2013-06-04) ATM-p53 pathway causes G2/M arrest, but represses apoptosis in pseudolaric acid B-treated HeLa cells.Guodong Yao et al.Archives of biochemistry and biophysics, 558, 51-60 (2014-06-15) Thermodynamic and phylogenetic insights into hnRNP A1 recognition of the HIV-1 exon splicing silencer 3 element.Carrie Rollins et al.Biochemistry, 53(13), 2172-2184 (2014-03-19) IDH1 mutations is prognostic marker for primary glioblastoma multiforme but MGMT hypermethylation is not prognostic for primary glioblastoma multiforme.Rasime Kalkan et al.Gene, 554(1), 81-86 (2014-12-03) Adenovirus-encoding virus-associated RNAs suppress HDGF gene expression to support efficient viral replication.Saki Kondo et al.PloS one, 9(9), e108627-e108627 (2014-10-03) [Methods for detection of methylated cytosine residues in DNA].S A Smirnikhina et al.Molekuliarnaia biologiia, 43(3), 387-391 (2009-07-29) Versatile ene-thiol photoclick reaction for preparation of multimodal monolithic silica capillary columns.A Marechal et al.Journal of chromatography. 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Section D, Biological crystallography, 70(Pt 9), 2477-2486 (2014-09-10) Environmental epigenetic inheritance through gametes and implications for human reproduction.Yanchang Wei et al.Human reproduction update, 21(2), 194-208 (2014-11-25) Spatial distribution of 5-hydroxymethyl cytosine in rat brain and temporal distribution in striatum.Tingting Zheng et al.Neurochemical research, 40(4), 688-697 (2015-02-04) Aberrant Toll-like receptor 2 promoter methylation in blood cells from patients with pulmonary tuberculosis.Yung-Che Chen et al.The Journal of infection, 69(6), 546-557 (2014-09-15) Analysis of the DNA methylome and transcriptome in granulopoiesis reveals timed changes and dynamic enhancer methylation.Michelle Rönnerblad et al.Blood, 123(17), e79-e89 (2014-03-29) Use of individual retention modeling for gradient optimization in hydrophilic interaction chromatography: separation of nucleobases and nucleosides.Eva Tyteca et al.Journal of chromatography. A, 1368, 125-131 (2014-12-03) Peripheral nerve injury induces persistent vascular dysfunction and endoneurial hypoxia, contributing to the genesis of neuropathic pain.Tony K Y Lim et al.The Journal of neuroscience : the official journal of the Society for Neuroscience, 35(8), 3346-3359 (2015-02-27) Cyclic di-GMP riboswitch-regulated type IV pili contribute to aggregation of Clostridium difficile.Eric Bordeleau et al.Journal of bacteriology, 197(5), 819-832 (2014-12-17) Estetrol attenuates neonatal hypoxic-ischemic brain injury.Ekaterine Tskitishvili et al.Experimental neurology, 261, 298-307 (2014-08-01) Molecular characterization of a Chinese family carrying a novel C4329A mutation in mitochondrial tRNAIle and tRNAGln genes.Yuqi Liu et al.BMC medical genetics, 15, 84-84 (2014-07-25) HSPA1A-independent suppression of PARK2 C289G protein aggregation by human small heat shock proteins.Melania Minoia et al.Molecular and cellular biology, 34(19), 3570-3578 (2014-07-16) Epigenetic profiles as defined signatures of xenobiotic exposure.John P Thomson et al.Mutation research. Genetic toxicology and environmental mutagenesis, 764-765, 3-9 (2013-09-05) Endonuclease G preferentially cleaves 5-hydroxymethylcytosine-modified DNA creating a substrate for recombination.Adam B Robertson et al.Nucleic acids research, 42(21), 13280-13293 (2014-10-31) High-energy chemistry of formamide: a unified mechanism of nucleobase formation.Martin Ferus et al.Proceedings of the National Academy of Sciences of the United States of America, 112(3), 657-662 (2014-12-10) The curious chemical biology of cytosine: deamination, methylation, and oxidation as modulators of genomic potential.Christopher S Nabel et al.ACS chemical biology, 7(1), 20-30 (2011-10-19) Childhood exposure to ambient polycyclic aromatic hydrocarbons is linked to epigenetic modifications and impaired systemic immunity in T cells.K M Hew et al.Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology, 45(1), 238-248 (2014-07-23) Dynamic switching of active promoter and enhancer domains regulates Tet1 and Tet2 expression during cell state transitions between pluripotency and differentiation.Abhishek Sohni et al.Molecular and cellular biology, 35(6), 1026-1042 (2015-01-15) TET enzymatic oxidation of 5-methylcytosine, 5-hydroxymethylcytosine and 5-formylcytosine.Jean Cadet et al.Mutation research. Genetic toxicology and environmental mutagenesis, 764-765, 18-35 (2013-09-21) The performance of BRCA1 immunohistochemistry for detecting germline, somatic, and epigenetic BRCA1 loss in high-grade serous ovarian cancer.J L Meisel et al.Annals of oncology : official journal of the European Society for Medical Oncology, 25(12), 2372-2378 (2014-10-05) Evaluation and comparison of the kinetic performance of ultra-high performance liquid chromatography and high-performance liquid chromatography columns in hydrophilic interaction and reversed-phase liquid chromatography conditions.Huiying Song et al.Journal of chromatography. A, 1369, 83-91 (2014-12-03) Separation of therapeutic peptides with cyclofructan and glycopeptide based columns in hydrophilic interaction liquid chromatography.Yang Shu et al.Journal of chromatography. A, 1390, 50-61 (2015-03-17) DNA cytosine methylation in plant development.Meishan Zhang et al.Journal of genetics and genomics = Yi chuan xue bao, 37(1), 1-12 (2010-02-23) The DNA methylation signature of human TCRαβ+CD4-CD8- double negative T cells reveals CG demethylation and a unique epigenetic architecture permissive to a broad stimulatory immune response.Paul A Renauer et al.Clinical immunology (Orlando, Fla.), 156(1), 19-27 (2014-12-03) A two-step process for epigenetic inheritance in Arabidopsis.Todd Blevins et al.Molecular cell, 54(1), 30-42 (2014-03-25) Prognostic potential of DNA methylation and transcript levels of HIF1A and EPAS1 in colorectal cancer.Agnieszka Anna Rawłuszko-Wieczorek et al.Molecular cancer research : MCR, 12(8), 1112-1127 (2014-05-16) The influence of organic sample solvents on the separation efficiency of basic compounds under strong cation exchange mode.Zhen Long et al.Analytica chimica acta, 872, 77-83 (2015-04-22) DNA polymorphism and epigenetic marks modulate the affinity of a scaffold/matrix attachment region to the nuclear matrix.Natalia P Kisseljova et al.European journal of human genetics : EJHG, 22(9), 1117-1123 (2014-01-23) TLR9 signalling in microglia attenuates seizure-induced aberrant neurogenesis in the adult hippocampus.Taito Matsuda et al.Nature communications, 6, 6514-6514 (2015-03-10) Intravenous administration of retroviral replicating vector, Toca 511, demonstrates therapeutic efficacy in orthotopic immune-competent mouse glioma model.Tiffany T Huang et al.Human gene therapy, 26(2), 82-93 (2014-11-25) Epigenetic tinkering and evolution: is there any continuity in the role of cytosine methylation from invertebrates to vertebrates?M Mandrioli Cellular and molecular life sciences : CMLS, 61(19-20), 2425-2427 (2004-11-05) Incorporation of thio-pseudoisocytosine into triplex-forming peptide nucleic acids for enhanced recognition of RNA duplexes.Gitali Devi et al.Nucleic acids research, 42(6), 4008-4018 (2014-01-16) Evaluation of molecular models for the affinity maturation of antibodies: roles of cytosine deamination by AID and DNA repair.Mala Samaranayake et al.Chemical reviews, 106(2), 700-719 (2006-02-09) Effects of doxorubicin and gemcitabine on the induction of apoptosis in breast cancer cells.Rui-Rui Zheng et al.Oncology reports, 32(6), 2719-2725 (2014-10-02) Photochemistry. Chemiexcitation of melanin derivatives induces DNA photoproducts long after UV exposure.Sanjay Premi et al.Science (New York, N.Y.), 347(6224), 842-847 (2015-02-24) Discovery of bisulfite-mediated cytosine conversion to uracil, the key reaction for DNA methylation analysis--a personal account.Hikoya Hayatsu Proceedings of the Japan Academy. Series B, Physical and biological sciences, 84(8), 321-330 (2008-10-23) Bisulfighter: accurate detection of methylated cytosines and differentially methylated regions.Yutaka Saito et al.Nucleic acids research, 42(6), e45-e45 (2014-01-16) Tet oxidizes thymine to 5-hydroxymethyluracil in mouse embryonic stem cell DNA.Toni Pfaffeneder et al.Nature chemical biology, 10(7), 574-581 (2014-05-20) Cytosine modifications in neurodevelopment and diseases.Bing Yao et al.Cellular and molecular life sciences : CMLS, 71(3), 405-418 (2013-08-06) Adenine suppresses IgE-mediated mast cell activation.Prashanta Silwal et al.Molecular immunology, 65(2), 242-249 (2015-02-24) TET2 gene expression and 5-hydroxymethylcytosine level in multiple sclerosis peripheral blood cells.Calabrese R, Valentini E, Ciccarone F, et al. Biochimica et Biophysica Acta, 1842(7), 1130-1136 (2014) Cytosine methylation and DNA repair.C P Walsh et al.Current topics in microbiology and immunology, 301, 283-315 (2006-03-31) Origin of life. From hell on Earth, life's building blocks.Sid Perkins Science (New York, N.Y.), 346(6215), 1279-1279 (2014-12-17) Genetic mosaicism of a frameshift mutation in the RET gene in a family with Hirschsprung disease.Charlotte M Müller et al.Gene, 541(1), 51-54 (2014-03-13) The performance of BRCA1 immunohistochemistry for detecting germline, somatic, and epigenetic BRCA1 loss in high-grade serous ovarian cancer.J L Meisel et al.Annals of oncology : official journal of the European Society for Medical Oncology, 25(12), 2372-2378 (2014-10-05) DNA cytosine methylation in plant development.Meishan Zhang et al.Journal of genetics and genomics = Yi chuan xue bao, 37(1), 1-12 (2010-02-23) Epigenetic DNA-(cytosine-5-carbon) modifications: 5-aza-2'-deoxycytidine and DNA-demethylation.S K Patra et al.Biochemistry. Biokhimiia, 74(6), 613-619 (2009-08-04) Origin of life. From hell on Earth, life's building blocks.Sid Perkins Science (New York, N.Y.), 346(6215), 1279-1279 (2014-12-17) Cytosine modifications in neurodevelopment and diseases.Bing Yao et al.Cellular and molecular life sciences : CMLS, 71(3), 405-418 (2013-08-06) Adenine suppresses IgE-mediated mast cell activation.Prashanta Silwal et al.Molecular immunology, 65(2), 242-249 (2015-02-24) Temozolomide and pasireotide treatment for aggressive pituitary adenoma: expertise at a tertiary care center.Filippo Ceccato et al.Journal of neuro-oncology, 122(1), 189-196 (2015-01-04) Cidofovir gel as treatment of follicular spicules in multiple myeloma.Sander van Boheemen et al.JAMA dermatology, 151(1), 82-84 (2014-09-05) TET proteins: on the frenetic hunt for new cytosine modifications.Benjamin Delatte et al.Briefings in functional genomics, 12(3), 191-204 (2013-04-30) TET2 gene expression and 5-hydroxymethylcytosine level in multiple sclerosis peripheral blood cells.Calabrese R, Valentini E, Ciccarone F, et al. Biochimica et Biophysica Acta, 1842(7), 1130-1136 (2014) Cytosine methylation and DNA repair.C P Walsh et al.Current topics in microbiology and immunology, 301, 283-315 (2006-03-31) Iron overload accelerates neuronal amyloid-β production and cognitive impairment in transgenic mice model of Alzheimer's disease.Javier Becerril-Ortega et al.Neurobiology of aging, 35(10), 2288-2301 (2014-05-28) Genome-wide DNA methylation as an epigenetic consequence of Epstein-Barr virus infection of immortalized keratinocytes.Christine E Birdwell et al.Journal of virology, 88(19), 11442-11458 (2014-07-25) Thrombin-facilitated efflux of D-[3H]-aspartate from cultured astrocytes and neurons under hyponatremia and chemical ischemia.M Pérez-Domínguez et al.Neurochemical research, 39(7), 1219-1231 (2014-04-08)
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